• Title/Summary/Keyword: C-Pilot

Search Result 595, Processing Time 0.031 seconds

The Effect of Hinged Ankle-Foot Orthosis on Walking Function in Children With Spastic Diplegic Cerebral Palsy: A Cross-Sectional Pilot Study

  • Kang, Jeong-Hyeon;Kim, Chang-Yong;Ohn, Jin-Moo;Kim, Hyeong-Dong
    • The Journal of Korean Physical Therapy
    • /
    • v.27 no.1
    • /
    • pp.43-49
    • /
    • 2015
  • Purpose: The aim of the current study was to examine the effects of hinged ankle-foot orthosis (HAFO) on walking function in children with spastic diplegic cerebral palsy (CP). Methods: Thirty-two children (mean age: $6.79{\pm}0.35years$, age range: 5-7 years) who were diagnosed with spastic diplegic cerebral palsy participated in the study. Each subject typically walked through 10 meters of a gait platform with markers on the subject's proper body segments and underwent 3-D motion analysis system with and without hinged ankle-foot orthosis. The HAFOs were all custom-made for individual CP children and had plantarflexion stop at $0^{\circ}C$ with no dorsiflexion stop. The interventions were conducted over three trials in each group, and measurements were performed on each subject by one examiner in three trials. 3-D motion analysis system was used to measure gait parameters such as walking velocity, cadence, step-length, step-width, stride-length, and double support period in two conditions. Results: The walking velocity, cadence, step-length, and stride-length were significantly greater for the HAFO condition as compared to the no HAFO condition (p<0.05). However, no significant difference in step-width and double support period was observed between two conditions. Conclusion: These findings suggest that using the HAFO during walking would suggest positive evidence for improving the spatiotemporal parameters of gait in children with spastic diplegic cerebral palsy.

A Study on the Sludge-reduced Sewage Treatment Process Combined with Sludge Solubilization Technique Using Alkalophiles (호알칼리미생물을 이용한 슬러지감량형 하수처리공정 연구)

  • Shin, Kyung-Sook;Kim, Yoon-Seok;Han, Dae-Hoon;Han, Woon-Woo;Rhee, Young-Ha;Hur, Hyung-Woo
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.21 no.6
    • /
    • pp.737-744
    • /
    • 2007
  • Recently, one of the most interesting topic in the field of wastewater treatment is the disposal of excess sludge. The new concept of excess sludge reduction with recirculation of solubilized sludge via effective microorganisms for cell disruption within the wastewater treatment process has been developed in this study. The alkalophiles for degradation of sludge cell wall were isolated as Exiguobacterium sp., which could be more effectively solubilized sludge in the anaerobic condition. The SCOD of solubilized excess sludge by Exiguobacterium sp. was up to about 2,000mg/L and average TN and TP concentration of solubilized component were 117mg/L and 58mg/L, respectively and C/N ratio was more than 17. To investigate the effects of solubilized sludge by alkalophiles on excess sludge reduction and nutrient removal efficiency, the pilot plant of $DF^{(S)}-MBR$ process, combined with membrane bioreactor and sludge solubilization tank, was operated. In the control run(without sludge solubilization), the daily sludge production was about 4.54 kgMLVSS/day. However, in the $DF^{(S)}-MBR$(with sludge solubilization), the daily sludge production was decreased to 1.39kgMLVSS/day. The effluent quality satisfied the effluent regulation in both cases. Furthermore, the $DF^{(S)}-MBR$ showed relatively better TN removal efficiency in spite of high influent loading. So we concluded that the solubilized excess sludge by alkalophiles was effectively degraded in the MBR process as the carbon source and 70% of sludge reduction efficiency can be achieved.

The composition control of ITO/PET by Plasma Emission Monitors (PEM을 이용한 ITO/PET film 조성 제어)

  • 한세진;김용한;김영환;이택동
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 1999.07a
    • /
    • pp.213-213
    • /
    • 1999
  • 현재 LCD용 기판재료는 ITO/glass를 전극으로 사용하고 있다. 그러나 유리기판은 무겁고 깨지기 쉽기 때문에 사용상 곤란한 점이 많다. 최근 flexible하고 가공성 및 생산성이 우수한 플라스틱한 ITO를 성막하여 EL용, Touch panel, plastic LCD용 사용하려는 시도로, roll-to-roll 연속 스퍼터링에 의한 ITO성막공정에 대한 연구가 최근 활발하게 이루어지고 있다. 폴리머는 유리에 비해 Tg 온도가 낮고, 기판으로부터의 수분 및 여러 종류의 가스방출이 심하기 때문에 유리와는 달리 ITO막의 제조에 있어 큰 차이점이 있다. 따라서, 폴리머에 반응성 스퍼터링을 하기 위해서는 표면처리가 중요한 변수가 되며, roll to roll sputter로 ITO 필름을 얻기 위해서는 폭과 길이 방향으로 균일한 막을 얻는 것이 중요하다. 두께 75$\mu\textrm{m}$, 폭 190mm, 길이 400m로 권취된 광학용 Polyethylene terephthalate(PET:Tg:8$0^{\circ}C$)위에 In-10%Sn의 합금타겟과 Unipolar pulsed DC power supply를 사용하여 반응성 마그네트론 스퍼터링 방법으로 0.2m/min의 속도로 연속 스퍼터링 하였다. PET를 Ar/O2 혼합가스로 플라즈마 전처리를 한 후, AFM, XPS를 이용하여 효과를 분석을 하였고, 성막전에 가스방출을 막기 위해 TiO를 코팅하였다. Pilot 연속 생산공정에서 재현성을 위해 PEM(Plasma Emission Monitor)의 optical emission spectroscopy를 이용, 금속과 산화물의 천이구역에서 sprtter된 I/Sn 이온과 산소 이온의 반응에 의한 최적의 플라즈마의 강도값을 입력하여 플라즈마의 radiation을 검출하고, 스퍼터링 공정중 실질적인 in-situ 정보로 이용하였다. PEM을 통하여 In/Sn의 플라즈마 강도변화를 조사하였다. 초기 In/Sn의 플라즈마 강도(intensity)는 강도를 100하여, 산소를 주입한 결과, plasma intensity가 35 줄어들었고, 이때 우수한 ITO 박막을 얻을 수 있었다. Pulsed DC power를 사용하여 아크 현상을 방지하였다. PET 상에 coating 된 ITO 박막의 표면저항과 광투과도는 4-point prove와 spectrophotometer를 이용하여 분석하였고, AES로 박막의 두께에 따른 성분비를 확인하였다. ITO 박막의 광투과도는 산소의 유량과 sputter 된 In/Sn ion의 plasma emission peak에 따라 72%-92%까지 변화하였으며, 저항은 37$\Omega$/$\square$ 이상을 나타내었다. 박막의 Sn/In atomic ratio는 0.12, O/In의 비율은 In2O3의 화학양론적 비율인 1.5보다 작은 1.3을 나타내었다.

  • PDF

Estrogen Receptor Alpha Gene Expression in Breast Cancer Tissues from the Iranian Population - a Pilot Study

  • Hosseini, Arezoo;Gopalan, Vinod;Nassiri, Mohammadreza;Ghaffarzadehgan, Kamran;Aslaminejad, Ali;Ghovvati, Shahrokh;Smith, Robert A.;Lam, Alfred K.Y.
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.20
    • /
    • pp.8789-8791
    • /
    • 2014
  • Estrogen receptor alpha ($ER{\alpha}$) is one of the major sub-types of estrogen receptors. $ER{\alpha}$ plays an important role in cellular proliferation and differentiation, chiefly in mammary tissues. In the present study we aimed to quantify of $ER{\alpha}$ mRNA and protein expression in breast tissues from the Iranian population using a real-time PCR assay. Twenty nine breast tissues including 19 adenocarcinomas and 10 normal controls were recruited from the Iranian population. mRNA extraction and cDNA synthesis were performed from these tissues using commercial kits. $ER{\alpha}$ mRNA and protein expression was quantified using real-time PCR and immunohistochemistry respectively. The results showed high expression of $ER{\alpha}$ mRNA (68%) and protein (53%) in the majority of breast cancer tissues compared to normal breast tissues (p= 0.035). Also, high $ER{\alpha}$ mRNA was associated with tumour size of breast carcinomas. In this study, we first reported the expression of $ER{\alpha}$ in Iranian patients with breast cancers and demonstrated prevalence of the expression to be similar to breast cancers noted in other populations.

Outcome of Daily Cisplatin with Thoracic Chemoradiotherapy in Advanced Non-small Cell Lung Cancer Patients with Comorbid Disorders: a Pilot Study

  • Kiziltan, Huriye Senay;Bayir, Ayse Gunes;Tastekin, Didem;Coban, Ganime;Eris, Ali Hikmet;Aydin, Teoman;Mayadagli, Alparslan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.20
    • /
    • pp.8591-8594
    • /
    • 2014
  • Background: Lung cancer is the most common cancer in males worldwide. The principal mode of treatment in the early stage of non-small cell lung cancer (NSCLC) is surgery. However, five-year survival is only about 15% for all stages. The aim is to investigate the effect of daily low dose cisplatin concurrently with radiation therapy in advanced NSCLC patients with poor performance status. Materials and Methods: Ten patients diagnosed as inoperable Stage IIIB NSCLC with comorbid disease were assessed retrospectively in Bezmialem Vakif University, Faculty of Medicine, Department of Radiation Oncology, between 2011 to 2013. ECOG performance status was between 3 and 4. Cisplatin was administered at $6mg/m^2$ daily, for 5 days a week concurrently with radiotherapy using 160-200 cGy daily fractions, 54 Gy being the lowest and 63 Gy being the highest dose. Results: Complete response at the primary tumour site was obtained in 20% patients. Grade I esophagitis was seen 70 percent of patients, and the grade II haematological toxicity rate was 20 %. Median survival time was 7 months. Conclusions: Median survival time was reasonable, despite the patients ECOG performance status of 3-4, which is similar to groups even without comorbid disorders in comparison to other published papers in the literature. Acceptable toxicity, high response rates and quality of life of patients are the other favourable features.

Reproduction Efficiency and Health Traits in Dorper, White Dorper, and Tsigai Sheep Breeds under Temperate European Conditions

  • Gavojdian, D.;Budai, C.;Cziszter, L.T.;Csizmar, N.;Javor, A.;Kusza, S.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.28 no.4
    • /
    • pp.599-603
    • /
    • 2015
  • The objective of the current pilot study was to evaluate the reproductive performance and health indicators in Dorper, White Dorper, and Tsigai breed ewes managed semi-intensively under European temperate conditions. A total of 544 ewe-year units were observed, with ewes (ranging from 1.5 to 8 years of age) managed under identical rearing conditions for a period of two consecutive production cycles (2012 through 2013 and 2013 through 2014). In general, significant ($p{\leq}0.001$) genotype-related disparities were found in occurrence rates for all health parameters taken into study. Clinical mastitis incidence was significantly lower ($p{\leq}0.05$) in Dorper (9.4%) and White Dorper (10.8%) breeds compared to that of Tsigai ewes (17.4%). Significant differences ($p{\leq}0.05$) for lameness were found between Dorper and Tsigai breeds, with occurrence rates of 8.0% and 2.9%, respectively. Incidence for pneumonia and abortion was not influenced (p>0.05) by the ewes' genotype. Litter size was significantly lower ($p{\leq}0.05$) in White Dorper breed than for Dorper and Tsigai ewes, of 1.21, 1.40, and 1.45, respectively. Conception rates and lambs survival were not affected (p>0.05) by genotype. Results suggest that South African Dorper and White Dorper sheep breeds have adapted well to the specific rearing conditions.

A Study on Difference of Clothing Image Evaluation by Gender (성에 따른 의복이미지 평가의 차이에 관한 연구)

  • 유경숙
    • Journal of the Korean Society of Costume
    • /
    • v.52 no.3
    • /
    • pp.87-98
    • /
    • 2002
  • The purpose of this research is to investigate the difference on c1othing image evaluation in the ratings between men and women. For this study, pilot test was conducted to 50 clothing majored university students to explore the stimulus of 'cute', 'casual', 'sexy', 'elegant', 'intelligent', 'formal', 'romantic', 'individual', 'refined' for the 9 each image styles from the 32 spring wears in fashion magazine $\ulcorner$FARBE$\lrcorner$(March. 2000). On the basis of the preliminary survey, the question items explored the 15 pairs of polar adjectives as seven-point Likert Scale. The main survey was preceded 94 female and 111 man of university students from March 13 to 24 in 2000, twice for 7-days interval. There were significant differences between the two sexes for each style image ratings. It was found that the female was recorded mote ordinary, stable. refined. superior, plain, like than the male for intelligent style. Meanwhile, the intelligent style was evaluated well on in years by female, but male young. The female tended that elegance style was more stable, warm and less young than the male. The cute style was evaluated more light, tender, feminine, young by the female than the male, find the female looked warm while the male cool. The formal style was more stable, unrefined. solid, unfamiliar dislike, old by the female than the male. The casual style was revealed plain and warm by the female while splendor and cool by the male, the female more active, tender, familiar than the male and individual, attractive and poor quality than the female. The sexy style was evaluated more active, good appearance, young than the female, tender than the male and the female dislike a bit while the male like. The female evaluated the refined style for more stable. refined. superior good appearance and nature than the male. The romantic style was evacuated more like, refined, superior, good appearance nature and familiar by the male, but the female a bit unfamiliar. The individual style was revealed that the female evaluated cool and a bit dislike while the male warm and like, and the male more refined, feminine, young than female.

Efficient Usage of Secondary Scramble Code via Optical Repeater in W-CDMA System (W-CDMA 시스템에서 광중계기를 이용한 secondary-스크램블 코드의 효율적 활용방안에 대한 연구)

  • Jeon, Eun-Sung;Park, Jun-Hyo;Yang, Jang-Hoon;Kim, Dong-Ku
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.34 no.8C
    • /
    • pp.731-741
    • /
    • 2009
  • Optical repeater is often installed at the isolated area. Spatial separation makes it possible to reduce the inter-code interference when secondary scrambling codes are used for traffic connected through repeater. In this paper, we propose five secondary scrambling code usage scenarios with the aids of optical repeater to maximize the user capacity. In order to evaluate the performance, dynamic system level simulation is performed. We also propose a base station-repeater switching where each active users can change access points by comparing the channel condition from base station and repeater thorough secondary common pilot channel (S-CPICH) signal to noise-interference ratio (SINR). Moreover, primary-secondary scramble code replacing scheme is proposed which replaces secondary scramble code with primary scramble code when a call using primary scramble code is ended and its corresponding OVSF code is available to users using the secondary scramble code

Performance Improvement of Channel Estimation based on Time-domain Threshold for OFDM Systems (시간영역 문턱값을 이용한 OFDM 시스템의 채널 추정 성능 향상)

  • Lee, You-Seok;Kim, Hyoung-Nam
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.33 no.9C
    • /
    • pp.720-724
    • /
    • 2008
  • Channel estimation in OFDM systems is usually carried out in frequency domain based on the least-squares (LS) method and the minimum mean-square error (MMSE) method with known pilot symbols. The LS estimator has a merit of low complexity but may suffer from the noise because it does not consider any noise effect in obtaining its solution. To enhance the noise immunity of the LS estimator, we consider estimation noise in time domain. Residual noise existing at the estimated channel coefficients in time domain could be reduced by reasonable selection of a threshold value. To achieve this, we propose a channel-estimation method based on a time-domain threshold which is a standard deviation of noise obtained by wavelet decomposition. Computer simulation shows that the estimation performance of the proposed method approaches to that of the known-channel case in terms of bit-error rates after the Viterbi decoder in overall SNRs.

Effect of Oncostatin M on Proliferation and Matrix Synthesis of Dermal Fibroblasts (Oncostatin M이 피부섬유모세포의 증식과 기질생성에 미치는 영향)

  • Chun, Kyung Wook;Lim, Hyung Woo;Han, Seung-Kyu;Kim, Woo Kyung
    • Archives of Plastic Surgery
    • /
    • v.35 no.2
    • /
    • pp.115-120
    • /
    • 2008
  • Purpose: Oncostatin M(OSM) is a multifunctional cytokine that belongs to the interleukin(IL)-6 family. Although there have been a number of studies that focused on the role and mechanism of OSM in various organs and tissues, there are few reports on its effect on wound healing. The final purpose of this project is to evaluate the effect of OSM on wound healing. This pilot study was designed to investigate the effect of OSM on proliferation and matrix synthesis of human dermal fibroblasts, which are the major components of the wound healing. Methods: Excess skin that was obtained from patients who underwent skin grafts, was used for this study. From this material, fibroblasts were isolated and cultured. The cultured fibroblasts were treated with one of four concentrations of OSM. The OSM concentrations used were 0, 50, 100, and 200 ng/ml, respectively. After the OSM treatment, cell proliferation was determined by the MTT assay, collagen synthesis by the C1CP method, GAG levels by the Blyscan Dye method. The parameter levels of each group were compared. Results: OSM treatment increased all the components tested in the study. In particular, cell proliferation, GAG synthesis demonstrated statistically significant increases(p<0.05 in the Mann-Whitney U-test). The highest increase in all the components was obtained at a 100 ng/ml concentration of OSM.Conclusion: The results of the present study indicate that OSM stimulates proliferation and matrix synthesis of human dermal fibroblast and the optimal concentration for wound healing is 100 ng/mL.