• Korean Journal of Veterinary Research
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• v.29 no.2
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• pp.51-57
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• 1989

This study was performed to investigate the toxicity of ochratoxin A (OA) to the chromosomes of $K_{562}$ tumor cell-line in vitro. The results of this experiment were as follows: 1) Chromosomes of $K_{562}$tumor cell-line resulted in pseudotriploidy on the control group. Chromosomes of $K_{562}$ tumor cell-line treated with OA resulted in heteroploidy compared with the control group. The mean number of chromosomes in the karyotype of the control group (60) were 7 in the A group, 5 in the B group, 20 in the C+X group, 7 in the D group, 9 in the E group, 6 in the F group, and 6 in the G+Y group respectively. The number of chromosomes were increased as follows: Treating with $0.7{\mu}M$ OA, the number of chromosomes were increased one in E and F group, two in G+Y group compared with control group. In treated with $1.5{\mu}M$ OA, the increasing number of chromosome was one in E and F group. In treated with $3{\mu}M$ OA, E and F group was increased one and G+Y group were increased two chromosomes compared with control group. But in treated with $6{\mu}M$ OA, the number of chromosome in G+Y group was decreased one. 2) $K_{562}$ tumor cell line treated with OA showed Philadelphia-Chromosome in the long arm of the G group karyotype chromosome. The rate of chromosome aberration in $K_{562}$ tumor cell-line treated with OA was 77% in $0.7{\mu}M$ OA group, 71% in $1.5{\mu}M$ OA group, 82% in $3{\mu}M$ OA group and 94% in $6{\mu}M$ OA group respectively. The rate of chromosome aberration of $K_{562}$ tumor cell-line treated with OA was high in the high dose level of OA, and chromosome aberration of $K_{562}$ tumor cell-line treated with OA showed deletion, minute, dicentric-chromosome and translocation in the long arm of the C-group karyotype. As a result of this study, the toxicity of OA showed deletion, minute, dicentric-chromosome and translocation in the long arm of the C-group karyotype, and then, the toxicity of OA resulted in the damage to RNA and protein synthesis in $K_{562}$ tumor cell-line, and the C-group karyotype of $K_{562}$ tumor cell-line was target of the toxicity of OA.

• The Korean Journal of Pain
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• v.26 no.1
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• pp.51-56
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• 2013

Background: The C-arm fluoroscope is an essential tool for the intervention of pain. The aim of this study was to investigate the radiation exposure experienced by the hand and chest of pain physicians during C-arm fluoroscopy-guided procedures. Methods: This is a prospective study about radiation exposure to physicians during transforaminal epidural steroid injection (TFESI) and medial branch block (MBB). Four pain physicians were involved in this study. Data about effective dose (ED) at each physician's right hand and left side of the chest, exposure time, radiation absorbed dose (RAD), and the distance from the center of the X-ray field to the physician during X-ray scanning were collected. Results: Three hundred and fifteen cases were included for this study. Demographic data showed no significant differences among the physicians in the TFESIs and MBBs. In the TFESI group, there was a significant difference between the ED at the hand and chest in all the physicians. In physician A, B and C, the ED at the chest was more than the ED at the hand. The distance from the center of the X-ray field to physician A was more than that of the other physicians, and for the exposure time, the ED and RAD in physician A was less than that of the other physicians. In the MBB group, there was no difference in the ED at the hand and chest, except for physician D. The distance from the center of the X-ray field to physician A was more than that of the other physicians and the exposure time in physician A was less than that of the other physicians. Conclusions: In conclusion, the distance from the radiation source, position of the hand, experience and technique can correlate with the radiation dose.

• Animal cells and systems
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• v.2 no.1
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• pp.113-116
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• 1998

A cDNA clone coding for ribosomal protein 46 (rp46) which is a component of 60S ribosomal large subunit has been identified from Drosophila melanogaster. A cDNA clone encoding S. cerevisiae rp46 was used as a probe to screen a Drosophila larvae cDNA library. The DNA sequence analysis revealed that the cDNA coding for Drosophils rp46 contains a complete reading frame of 153 nucleotides coding for 51 amino acids. The deduced amino acid sequence showed 71-75% homology with those of other eukaryotic organisms. Northern blot analysis showed that about 1-kb rp46 transcripts are abundant throughout fly development. Whole mount embryonic mRNA in situ hybridization also showed no preferential distribution of the transcripts to any specific region. The chromosomal in situ hybridization revealed that the identified gene is localized at position 60C on the right arm of the second polytene chromosome with a possibility of single copy.

• Proceedings of the Korean Information Science Society Conference
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• 2001.10c
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• pp.94-96
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• 2001

저전력 시스템에 대한 연구는 회로 수준에서부터 응용 소프트웨어 수준에 이르기까지 다양한 각도에서 이루어지고 있다. 본 연구에서 는 특히 운영 체제 수준, 즉 $\mu$C/OS-II(MicroC/OS-II) 커널 코드의 다양한 함수들에 대한 에너지 소비값을 추출하며 이 결과를 바탕으로 운영체재의 각 모듈별 에너지 소비를 분석한다. 이를 위하여 ARM7TDMI 마이크로 콘트롤러를 이용하여 제작된 시스템에 $\mu$C/OS-IIl 운영체제를 이식하고 SES(SNU Energy Scanner)툴을 이용하여 수행된 운영체제 코드의 각 모듈 즉 태스크 관리, 인터럽트 처리, IPC등에 대한 에너지 소비를 얻고 이 결과를 분석한다.

• The Korean Journal of Zoology
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• v.33 no.2
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• pp.217-221
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• 1990

The chromosomal analyses of Dendmcopos major hondoensis and D. leucotos Ieucotos(Picidae:Piciformes) in Korea were performed by conventional Giemsa staining and C-banding method. The diploid number of two species was 2n=90-92 and arm number was AN= 92-96.The conventional karyotypes were very similiar but distribution of constitutive heterochromatin were differ in the first chromosome. The second and several pairs of macro-telocentric chromosbmes have telomeric constitutive heterochromatin.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.7
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• pp.1653-1660
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• 2010

In this study, change of body surface temperature was measured using Digital Infrared Thermographic Imaging(DITI) to check muscle fatigue recovery & muscle pain control by magnetic stimulations. For clinical trials, subjects were divided into 3 groups : non stimulation group(NSG), electrical stimulation group(ESG) and micro magnetic stimulation group(MSG). In result, temperature differences between left and right arm surfaces were measured as much as $0.86{\pm}0.43^{\circ}C$(n=96) after the exercise, $0.78{\pm}0.12^{\circ}C$ after the electrical stimulation and $0.1{\pm}0.39^{\circ}C$ after the micro magnetic stimulation. Also after 3days, temperature differences between left and right arm surfaces were measured as much as $0.3{\pm}0.14^{\circ}C$ in the NSG, $0.05{\pm}0.21^{\circ}C$ in the ESG and $0.03{\pm}0.21^{\circ}C$ in the MSG. These data showed that the lowest temperature difference between left/right body surface was measured in MSG.

• Journal of the Korean Society of Safety
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• v.21 no.3 s.75
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• pp.53-58
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• 2006

Following a Mediterranean fruit fly outbreak in South Australia, a bait spray program involving the pesticides like malathion(MAL) was carried out. During the application, dermal exposure was considered for the pest controllers wearing PVC gloves. However there is a lack of information about PVC glove performance like break through times and permeation rates with MAL, therefore, a new analytical method for HPLC-UV was developed. A standard permeation test cell was used in this study. From the results of this study, more than 96% solubility of MAL was provided at 30% isopropyl alcohol in distilled water as a collecting media. However, there was significant decomposition of MAL when the solutions were kept at over $50^{\circ}C$ for 2-3 hours. As a mobile phase, 50% acetonitrile water solution (pH 6.0) gave the greater sensitivity compared with other compositions of acetonitrile solution. The arm section of the gloves had shorter breakthrough times and higher permeation rates compared with the palm. There was no malathion solution breakthrough up to 24 hours using the 1% MAL working strength solution. When the temperature was changed from $22{\pm}1^{\circ}C\;to\;37{\pm}1^{\circ}C$, the breakthrough times were decreased by 14.5% on palm and 37.5% on arm, and permeation rates were increased significantly. The findings of this study indicate that further investigations on used gloves, periods of use and varying working conditions like tasks and seasons should be carried out to assess potential worst case scenarios.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.13 no.2
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• pp.293-298
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• 2009

In this contribution, a 193-bit elliptic curve cryptography coprocessor was implemented on an FPGA board. Optimized algorithms and numerical expressions which had been verified through C program simulation, should be analyzed again with HDL (hardware description language) such as Verilog, so that the verified ones could be modified to be applied directly to hardware implementation. The reason is that the characteristics of C programming language design is intrinsically different from the hardware design structure. The hardware IP which was double-checked in view of hardware structure together with algoritunic verification, was implemented on the Altera CycloneII FPGA device equipped with ARM9 microprocessor core, to a real chip prototype, using Altera embedded system development tool kit. The implemented finite field calculation IPs can be used as library modules as Elliptic Curve Cryptography finite field operations which has more than 193 bit key length.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.11 s.176
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• pp.45-50
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• 2005

In this study, the casting/forging process was applied in manufacturing a low control arm, in order to prove that application of casting/forging process to Al6061 is likely to get the effect of light weight compared with existing steel products and to reduce the cost of materials. Firstly, In order to set up the optimum casting condition of the forging material, Al6061, casting experiments were carried out by controlling pouring temperature of the aluminum for casting, mold temperature, and pouring time. $700^{\circ}C$ pouring temperature, $300^{\circ}C$ mold temperature and 10-second pouring time were taken into account as the optimum casting conditions. With respect to a hot forging test, it is practiced on the basis of a temperature of materials, strain rate, and reduction rate so as to observe each microstructure and examine strain-stress curve simultaneously; examine tensile test and hardness test; eventually set up the optimum hot forging condition. A hot forging test, tensile test, hardness experiment, and microstructure observation were carried out on condition of $70\%$ reduction rate, $500^{\circ}C$ temperature of materials, and 1 strain rate. As a result of those experiments, 330MPa tensile strength, $16.4\%$ elongation, and 122.8Hv hardness were recorded. In oder to get a sound preform which has no unfitting cavity and less flash, two preforms were proposed on the basis of volume rate of the final product; the optimum volume rate of preform for the low control arm was $115\%$. In conclusion, it is confirmed that using the forging material rather than casting materials in casting/forging process is likely to get more superior mechanical properties. Compared with Al6061, performed by means of general forging, moreover, cast/forged Al6061 can not only stimulate productivity by reducing production processes, but cut down the cost of materials by reusing forging scraps.

• Korean Journal of Breeding Science
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• v.42 no.2
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• pp.163-168
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• 2010

This study was carried out to determine the chromosomal localization of the 5S and 18S-26S ribosomal DNA(rDNA) genes by means of fluorescence in situ hybridization(FISH) techniques, and the constitutive heterochromatin detected by means of Gimsa C-banding technique in rye(Secale cereale L.). The somatic chromosomes number was 2n=14. The karyotype consists of four pairs of metacentrics(chromosomes 1, 2, 3, and 7) and three pairs of submetacentrics(chromosomes 4, 5, and 6). Secondary constrictions appeared in the short arm of chromosome 1. The 5S rDNA genes have been located on two pairs of chromosomes 1 and 5, and 18S-26S rDNAs genes have been located on one pair of chromosome 1. 5S rDNA genes were detected on the distal region of the secondary constrictions in nucleolus organizer regions(NOR) in chromosome 1, and other detected on the intercalary region in the short arm of chromosome 5.