• Title/Summary/Keyword: Burst speed

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Preparation of Polycaprolactone Microcapsules by Membrane Emulsification Method and Its Drug Release Properties (막유화법에 의한 생분해성 Polycaprolactone 마이크로캡슐의 제조와 약물방출 특성)

  • Youm, Kyung-Ho;Yun, Tae-Ho;Kim, Kong-Soo;Cho, Suh-Hyeong
    • Membrane Journal
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    • v.17 no.1
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    • pp.67-79
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    • 2007
  • Uniform microcapsules containing ionic model drugs were prepared by controlling various conditions of emulsification procedure using a lab-scale membrane emulsification system with a SPG (Shirasu porous glass) tubular membrane. We observed the effects of various emulsification parameters [concentration and molecular weight of polycaprolatone (PCL) polymer, transmembrane pressure and emulsifier concentration in disperse phase and continuous phase, stirring speed] on the mean size and size ditribution of microcapsules containing lidocaine hydrochloride (cationic drug), sodium salicylate (nonionic drug) and 4-acetaminophen (anionic drug) used as a model drugs. Also, release characteristics of a model drugs from PCL microcapsules were investigated. Controlling membrane emulsification parameters, uniform PCL microcapsules with about $5\;{\mu}m$ of the mean size were finally prepared. The release rate and the burst effect of microcapsules were decreased in condition of the acidic solution, but it was increased in condition of the base solution.

The Probability of Solar Proton Events (SPEs) depending on solar and interplanetary type II bursts

  • Youn, Sae-Poom;Moon, Young-Jae;Park, Jin-Hye
    • Bulletin of the Korean Space Science Society
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    • 2011.04a
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    • pp.28.4-29
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    • 2011
  • Solar Proton Events (SPEs, ${\geq}\;10\;cm^{-1}s^{-1}sr^{-1}$ with >10 MeV) are very important for space weather forecasting. It is well known that they are associated with solar flares and/or CME-driven shocks. Especially, the CME-driven shocks have been observed as solar and interplanetary type II bursts. In this study, we estimated the occurrence probability of SPEs depending on three groups: (1) metric, (2) decameter-hectometric (D-H), and (3) meter-to-kilometric (m-to-km) type II bursts. For this work, we used SPEs and all available type II burst data in 1996-2004. The primary findings of this study are as follows. First, the majority (77%) of the m-to-km type II bursts are associated with SPEs and its probability is noticeably higher than D-H type II bursts probability strongly depend on longitude: eastern (0%), center(45%), and western (33%) for X-class associated metric type II bursts, eastern (15%), center (55%), and western (50%) for X-class associated D-H type II bursts, eastern (17%), center (77%), and western (64%) for X-class associated m-to-km type II bursts. Third, for m-to-km type II bursts, the SPE probability increases with CME speed: 400km/s${\leq}$V <1000km/s (36%), 1000km/s ${\leq}$V<1500km/s (40%), 1500km/s${\leq}$V (66%). Finally, we expect that these results will be used for setting up more reasonable solar proton event forecasting models.

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Electrical Resistivity Methods in Korea (한국의 전기비저항탐사)

  • Kim, Hee-Joon
    • Economic and Environmental Geology
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    • v.39 no.4 s.179
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    • pp.473-483
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    • 2006
  • Although application of electrical methods in Korea began with observation of self potentials before World War II, the methods were developed slowly by the beginning of 1980's when a major burst of development activity took place. DC resistivity methods are applied in Korea more to geotechnical problems rather than to environmental ones unlike other developed countries. As with every other branch of technology, the evolving speed of the silicon chip and of streaming data to hard disk has revolutionized data collection and noise reduction processing. The last two decades saw major advances in data collection, processing, and interpretation of electrical data. Development of smooth-model two-dimensional (2D) resistivity inversion is one of the most visible changes to geophysical interpretation of the last 40 years and is now routinely applied to apparent resistivity data. The ability to represent resistivities in section rather than pseudosection view has revolutionized interpretation. Although calculation of sensitivities for general electromagnetic problems require numerous forward modelings, DC resistivity methods can enjoy computational efficiencies if sources and receivers occupy the same position, and previously intractable 3D inversion is now becoming available.

Design of MAC Algorithm Supporting Adaptive Transmission Rate on VANET (VANET에서 적정 전송속도를 지원하는 MAC 설계)

  • Park, Sanghyun;Kim, Nam-Il
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.11
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    • pp.132-138
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    • 2012
  • VANET(Vehicular Ad-hoc Network), standardization of IEEE 802.11p specification is in process. 802.11 MAC protocol grants all nodes equal opportunity to acquire channel without regard to their bit-rates, making it possible for lower bit-rate nodes to occupy communication channel for a fair amount of time thus keeping the higher bit-rate nodes from acquiring connection channel which downward-equalize the overall network performance. Also with the 802.11p MAC protocol, the probability of collision occurring increases as the number of nodes grow. The proposed algorithm is a new MAC protocol that guarantees nodes with acquired channel a firm priority over other nodes for a fixed amount of time with TXOP concept added to 'packet burst' according to the current transmitting speed. This newly designed algorithm allows the construction of wireless network with enhanced network throughput, decreased probability of collisions as well as providing the means to grant each node a fair chance of acquiring connection according to their channel conditions. The algorithm sets the CW's (Contention Window) width wider than the standard's and modulates the continuous transmitting threshold value depending on channel acquired time, thus improving the overall performance of the network.

Development and Verification of Digital EEG Signal Transmission Protocol (디지털 뇌파 전송 프로토콜 개발 및 검증)

  • Kim, Do-Hoon;Hwang, Kyu-Sung
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38C no.7
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    • pp.623-629
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    • 2013
  • This paper presents the implementation result of the EEG(electroencephalogram) signal transmission protocol and its test platform. EEG measured by a dry-type electrode is directly converted into digital signal by ADC(analog-to-digital converter). Thereafter it is transferred DSP(digital signal processor) platform by $I^2C$(inter-integrated circuit) protocol. DSP conducts the pre-processing of EEG and extracts feature vectors of EEG. In this work, we implement the $I^2C$ protocol with 16 channels by using 10 or 12-bit ADC. In the implementation results, the overhead ratio for the 4 bytes data burst transmission measures 2.16 and the total data rates are 345.6 kbps and 414.72 kbps with 10-bit and 12-bit 1 ksps ADC, respectively. Therefore, in order to support a high speed mode of $I^2C$ for 400 kbps, it is required to use 16:1 and $(8:1){\times}2$ ratios for slave:master in 10-bit ADC and 12-bit ADC, respectively.

PLGA particles and half-shells prepared by double emulsion method: characterization and release profiles of ranitidine (이중 유제 방법으로 제조된 PLGA 미립자들과 반구체:특성과 라니티딘(ranitidine)의 방출 양상)

  • Nam, Dae-Sik;Kim, Seong-Cheol;Kang, Soo-Yong;Odonchimeg, Munkhjargal;Shim, Young-Key;Lee, Woo-Kyoung
    • Journal of Pharmaceutical Investigation
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    • v.38 no.2
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    • pp.99-104
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    • 2008
  • PLGA micro/nano particles encapsulating ranitidine as a hydrophilic model drug were prepared by the double-emulsion solvent evaporation method. Surface morphology investigation by scanning electron microscope (SEM) showed that the emulsification by sonication could produce nanoparticles, whereas microparticles were prepared using high speed homogenizer. Moreover, while nanohalf-shell structure instead of spherical nanoparticle could be produced by adding poloxamer into oil phase (MC) with PLGA 504H, the addition of poloxamer didn't change particle shape in case of PLGA 502H. On the other hand, microparticle with poloxamer had more surface pores than those without poloxamer. The size and polydispersity (PDI) of particles were determined by particle size analyzer. Effective diameters of particles were in the range of $400{\sim}800\;nm$ and $1200{\sim}3300\;nm$ in case of nanoparticles and microparticles, respectively. Encapsulation efficiencies were in the range of $1.2{\sim}2.9%$. The addition of poloxamer produced the particles with higher encapsulation efficiency. In vitro release study in phosphate buffer (pH 7.4) at $37^{\circ}C$ showed common large initial burst release. However, the relative slower release profile could be observed in case of microparticles. Poloxamer addition increased the release rate, which was thought to be related to the increased surface area of particles.

Study on DPSAM Turbo TCM in Time-Selective Fading Channels (시간 선택적 페이딩 채널 환경에서 DPSAM Turbo TCM에 관한 연구)

  • Kim, Jeong-Su
    • Journal of the Korea Society of Computer and Information
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    • v.18 no.11
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    • pp.107-113
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    • 2013
  • Mobile mobility and data reliability should be guaranteed as well as amounts of data services are essential in the era of smart media. In order to improve the reliability of high-speed data, strong channel coding and modulation techniques are required. In this paper, the structure of Turbo TCM decoder, applying high-order modulation techniques and the DPSAM method which improves performances in time-selective fading channels in the case of burst errors are suggested through the optimal decoding method and iteration decoding so as to improve bandwidth efficiency in Turbo Codes with excellent encoding gain. The proposed method in comparison with the existing method is that 3dB is superior in case that BER is $10^{-2}$ and the number of iterations is 3. In addition, the function is improved at approximately 6dB in case that BER is $10^{-3}$ and the number of iterations is 7. The proposed method requires additional bandwidth; however, the bandwidth loss can be overcome through Turbo TCM technology on the additional bit rate from the bandwidth loss.

Effects of Starvation and Delayed Feeding on Growth and Survival of Pacific Cod Gadus macrocephalus Larvae (대구, Gadus macrocephalus, 자어의 첫 섭식 시 기아와 늦은 먹이 공급이 성장과 생존에 미치는 영향)

  • Shin, Min-Gyu;Lee, So-Gwang;Jeon, Hae-Ryeon;Joo, Jae-Hyeong;Gwak, Woo-Seok
    • Korean Journal of Ichthyology
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    • v.31 no.1
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    • pp.7-15
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    • 2019
  • The present study aimed to investigate the influence of starvation on growth, survival and swimming ability of Pacific cod Gadus macrocephalus larvae. Notochord length, musculature height, body depth, gut height and volume of yolk of reared larvae were measured to determine the growth parameters. A significant difference was observed in all morphometric characteristics before 15 DAH (days after hatching). Body depth and volume of yolk of unfed larvae were significantly smaller than those of fed larvae from 9 DAH (P<0.05). Almost all yolk in fed group was consumed at 11 DAH. Survival and growth of larvae were observed to determine the effect of delayed initial feeding (2 DAH, 3 DAH, 4 DAH, unfed). All larvae in the unfed group died by 15 DAH and the larvae in other experimental groups survived until the end of the experiment to 21 DAH. Survival rate was not significantly different between the 2 DAH group ($17.5{\pm}4.27%$) and the 3 DAH group ($20.5{\pm}1.5%$) at 21 DAH (P>0.05). However, there was a significant difference in survival rate between the 3 DAH group and the 4 DAH group ($11.7{\pm}1.52%$) (P<0.05). There was no significant difference in notochord length among the groups fed from 2 DAH, 3 DAH and 4 DAH at 21 DAH (P>0.05). The swimming ability in fed group gradually increased in both cruising and burst swimming speeds, while those abilities in unfed group gradually decreased after reaching the peak at 6 DAH in both cruise ($18.7{\pm}6.56mm/s$) and burst swimming speed ($43.5{\pm}12.65mm/s$).

A architecture and control method of Streaming Packet Scheduler at 100bps for Guaranteed QoS of Internet and Broadcasting Services (인터넷 및 방송서비스의 QoS 보장을 위한 10Gbps급 스트리밍 패킷 스케줄러 구조 및 제어방법)

  • Kim Kwang-Ok;Park Wan-Ki;Choi Byeoun-Chul;Kwak Dong-Yong
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.41 no.1
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    • pp.23-34
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    • 2004
  • This paper presents architecture and control method of packet scheduler to guarantee QoS of high quality streaming services in high-speed packet-switched networks. Since streaming services need far more stringent QoS requirements than the typical sort of burst data applications, they should be guaranteed minimum bandwidth and end-to-end delay bound to each flow, regardless of the behavior of other flows. To meet these requirements, a packet scheduler isolate a flow from the undesirable effects of other flows and provides end-to-end delay guarantees for individual flow and divides stringently the available link bandwidth among flows sharing the link. Until now, many vendors are developing traffic management chips running at 10Gbps, but most of chips have drawbacks to support high quality streaming services. In this paper, we investigate the drawbacks of commercial TM chips and traffic characteristic of streaming services and present implementation frameworks of the proposed packet scheduler. Finally, we analyze the simulation results of the proposed scheduler.

Selection of Cultivars and Organic Solvents to Improve Fruit Set of Greenhouse Watermelon during Cold Period (저온기 시설수박 착과율 증진을 위한 품종 및 화분분리 유기용매 선발)

  • Lim, Chae-Shin
    • Journal of Bio-Environment Control
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    • v.19 no.3
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    • pp.147-152
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    • 2010
  • Poor fruit set during winter period is one of the biggest problem in plastic tunnel watermelon cultivation. Hand pollination is inevitable to maximize fruit set of the winter watermelon. Productivity and viability of pollen grain and organic solvents for pollen storage were investigated. All cultivars produced more than 10 mg/flower except for 'Kumchun' cultivar. Pollen amount per flower were 13.8 mg in 'Bok' and 12.1 mg in 'Speedkul'. Germination rate of pollen grains incubated at $30^{\circ}C$ right after soaking in pentane solvent were 76% in 'Kumchun' as the lowest and 92% in 'Apollokul' as the highest. The pollen of 'Bok' showed the highest germination rate by 75% after a 15-day storage in pentane. All cultivars showed their pollen germination rate below 25% after a 24-day storage. Among the cuitivars, speed of pollen tube growth in vitro were relatively lower in 'Kumchun' and 'Sambokkul' by below $50\;{\mu}m/hr$. Pollen tube of these cultivars tended to burst during its elongation on the medium. Pollen stored 24 hrs in organic solvents showed 45, 39, 34, 23, and 19% of germination in pentane, ethyl ether, n-hexane, ethyl acetate, and acetone, respectively. Compared with light condition, pollen viability was higher in darkness during pollen storage in organic solvents. Pollen grain was susceptible to the organic solvent. The viability of pollen grains seems to be influenced greatly by duration of soaking pollen in organic solvent and the polarity of solvents. Organic solvent damages surface of pollen grain and extent of damage was varied by the solvents.