An orally disintegrating film (ODF) based on hyaluronic acid (HA) containing vitamin D was developed. The vitamin D content in the ODF was set based on the adequate intake (AI) of vitamin D from 0 to 10 AI (0, 1, 4, 7, and 10AI). The control (0AI) had the highest thickness and showed the longest disintegration time among the samples. The moisture content of the ODFs was significantly lower in those with vitamin D compared to the control. As the amount of vitamin D increased, the water vapor permeability (WVP) of the ODFs decreased, and the opacity significantly increased. The tensile strength was higher in the films containing vitamin D compared to the control films. However, the elongation at the break showed no significant difference among the films. The vitamin D content in the film was reduced by 25.7-44.2% during processing compared to the amount that was originally added. Based on the above results, a new and convenient vitamin D delivery system, an ODF, could be successfully produced.
The purpose of this study is to examine the effects of social withdrawal, depression, aggression, negative parenting attitude as parental factors, friendship as school factors, academic helplessness and smartphone dependence, persistence, etc. on adolescent delinquency experiences as perceived personal factors. was carried out to understand. For this study, first year middle school students in the first year of the Korean Children and Youth Panel Survey (KCPYS 2018) were analyzed. As a result of the study, it was found that depression, aggression, social withdrawal as individual factors of adolescents, negative parenting attitude as parent factors, academic helplessness, negative friendships, smartphone dependence, persistence, etc. as school factors influence delinquent behavior of adolescents. In addition, it was found that smartphone dependence and persistence play a partial mediating role in the process of personal factors, parental factors, and school factors affecting adolescents' delinquency experiences. Based on these results, first, we need to break stereotypes about adolescents and understand the accurate understanding of adolescents' delinquent behaviors and what expectations they have. Second, practical education is required for parents and grandparents for consistent parenting attitudes and effective parenting. Third, a positive self-awareness and correct human relationship formation program should be operated in order to improve the friendship among adolescents. Finally, correct smartphone usage and counseling interventions and prevention programs to alleviate impulsivity are needed.
Journal of Korea Entertainment Industry Association
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v.15
no.4
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pp.45-54
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2021
Jeong Sun-Ah built up her performance career for twenty years with bold and energetic acting and solidified her status as a leading actress of Korean musical since her debut. To benefit from the value of her experience this study performed an in-depth interview with her, applying the Theory of "Projection" and "Back-projection", which are the psychological principles of acting, and derived "acting(entering the roles)" and "de-acting(leaving the roles)" techniques. As result, Her acting mechanism involved emptying her ego, embodying a persona by projecting the role created by intensive exploration of materials like previous performance, film of the same title, original novel, and script, and then getting the ego back by back-projecting through dynamic activities such as overseas travel and dance. She pre-studied the roles by physically visiting sites that are important to the characters. She was unique in that she pursued a difference by changing vocal trainers for each musical production and undertook more intense physical training than vocal practice to achieve powerful singing performance. In most of her works (75%), she suffered from aftereffects such as depression, narcissism, hysteria, and insomnia due to disorder caused by breaking away from the roles. However, she relied on self-help and alternatives are needed in the future such as reinforcement of expert counselling. Jeong Sun-Ah appeared on an average of 1.6 productions per year, practiced for an average of 1.7 months, and performed for an average of 3.9 months with an average of 100 days of break between productions. Her performance record from this research demonstrates her constant preparation and passion, as well as the know-how of reserving and distributing energy. So, it has a valuable implications for acting education and self-management of actors and actress.
The significance of the enactment of the 「Act On The Safety Of And Support For Advanced Regenerative Medicine And Advanced Biological Products」 is to break away from the regulation of the Pharmaceutical Affairs Act and expand patient treatment opportunities through a medical technology approach to regenerative medicine, which is essentially a medical practice called 'transplantation'. However, more than a year after the law was enacted, clinical study has not been activated, with not a single high-risk study approved by the Ministry of Food and Drug Safety being approved. The reason is that despite the legal purpose of expanding patient treatment opportunities, the data requirements for clinical study approval are set in connection with drug development despite the insufficient legal basis, making it difficult for many researchers to meet the data requirements. Prior to the enactment of the Act, submitted data for clinical study on cell therapy products within the Pharmaceutical Affairs Act were cosiderably exempted from quality and non-clinical test data, but with the enforcement of the Advanced Regenerative Bio Act, quality and non-clinical test data are required in accordance with pharmaceuticals when applying for approval of a clinical study plan. To rectify this, when considering the identity of clinical study on advanced regenerative medicine to expand treatment opportunities, recognize that there are limitations in connection with drug development. And it is necessary to preserve the identity of clinical study on advanced regenerative medicine, and on the other hand, in the case of drug product approval, clinical study results should be utilized while specifying usage requirements. Therefore, with the power of the market and the voluntary motive of the clinical researcher, it is necessary to prepare the necessary data by themselves rather than the basic requirements for clinical study approval.
Journal of Korea Entertainment Industry Association
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v.14
no.4
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pp.169-186
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2020
This study selected 127 powerful Korean film producers, directors, and actors whose stable audience drawing power has been proven over the past seven years from 2013 to 2019, and viewed their network through social network analysis(SNA) to explain their power structure. It also explained the changes compared to the results of previous studies conducted on box office hits from 1998 to 2012. The producers who showed the highest audience drawing power over the past seven years were KANG Hae-jung, JANG Won-seok, LEE Eugene, HAN Jae-duk. BONG Joon-ho, KIM Yong-hwa, and RYOO Seung-wan as directors and SONG Kang-ho, HA Jung-woo, and HWANG Jung-min as actors were confirmed to exhibit the most stable audience drawing power. Meanwhile, the network formed by the 127 leading producers, filmmakers, and actors was analyzed based on closeness/ degree/eigenvector/betwenness centrality, and the result discovered a strong network involving JANG Won-seok, HAN Jae-duk, CHO Jin-woong, Don LEE, and HWANG Jung-min. This study is meaningful in that it included producers, the position which has never been discussed in previous local studies to analyze the network influencing star casting, and selected accurate box office hits by checking whether the concerned films actually reached break-even point rather than simply relying on the number of audiences or total revenue they garnered. Nonetheless, it left a hole to be filled in that it did not include the role of the management companies in the network. Therefore, a relevant follow-up discussion would be needed.
Byunghyun Kim;Jundong Kim;GwangYeel Seo;Kyuseok Kim;HaeJeong Nam;YoonBum Kim
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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v.36
no.1
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pp.96-109
/
2023
Objectives : The objective of this study is to predict how future infectious diseases will affect healthcare utilization patterns within korean medicine hospitals and, specifically, departments of ophthalmology, otolaryngology and dermatology of Korean medicine. Methods : We retrospectively analyzed medical records of patients who visited Kyung Hee University Korean Medicine Hospital during Pre COVID-19(from March 1st, 2018 to Feb 29th, 2019) and Post COVID-19(from March 1st, 2019 to Feb 28th, 2022). The data was analyzed by visit type and diagnosed disease code. Results : 1. After the COVID-19 break-out, the number of first visit patients increased but those of revisit patients, total patients, and revisit/first visit ratio decreased in all departments. 2. In Kyung Hee University Korean Medicine Hospital, the decrease rate of the number of total patients diagnosed with diseases of respiratory system(J00-J99) was the highest, while that for diseases of circulatory system(I00-I99) was the lowest. 3. In the department of Ophthalmology and Otolaryngology of Korean Medicine, the decrease rate of the number of total patients with nose disease was the highest, followed by eye disease and ear disease. 4. In the department of Dermatology of Korean Medicine, the number of total patients with dermatitis remained consistent, while the number of total patients with skin appendage disease showed relatively high decrease rate. Conclusions : Severe or chronic diseases showed relatively low decrease rate of the number of total patients. While mild diseases or diseases with high probability of exposure to COVID-19 infection during treatment showed high decrease rate of the number of total patients.
Journal of the Korea institute for structural maintenance and inspection
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v.27
no.4
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pp.23-32
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2023
The seismic performance of buried PE pipes is reported to be favorable due to their exceptional elongation capacity at break. Although a seismic performance evaluation procedure based on the response displacement method has been summarized in Korea for fusion-bonded PE pipes, there is currently no procedure available for mechanically jointed PE pipes. This article aims to present a seismic performance evaluation procedure based on the response displacement method specifically designed for mechanically jointed PE pipes in Korea. When employing the mechanical joining method for PE pipes, it is recommended to adhere to the evaluation procedure established for segment-type pipes. This involves assessing the stress induced by the pipe, the expansion and contraction strain of the joint, and the bending angle of the pipe joint. Furthermore, the coefficient of inhomogeneity of the soil, which is necessary for estimating the axial strain of the ground, is introduced. Additionally, a computation method for determining lateral displacement and reconsolidation settlement in soil susceptible to liquefaction is proposed. As a result of the sensitivity analysis considering the typical soil condition in Korea, the mechanically jointed PE pipe with a certain quality was shown to have good structural seismic safety when soil liquefaction was not considered. This procedure serves as a valuable tool for seismic design and evaluating the seismic performance of mechanically joined buried PE pipes, which are primarily utilized for connecting small-diameter pipes.
The North Korean military's maneuver toward Honam was the fastest maneuver the North Korean army had demonstrated during the Korean War, and it was a threatening attack that forced the Korean and Allied forces to fully adjust the defenses of the Nakdong River. However, when this study analyzed the North Korean military's maneuver toward Honam in terms of indirect approach strategy, there were a number of factors that inevitably led to its failure. In terms of implementing the indirect approach strategy, the North Korean military cited a number of failure factors, including the dispersion of combat forces, the inflexibility of changing the line of operation, the maneuvering of ground forces, and the lack of psychological distaction. However, the North Koreans were preparing for a final "surprise attack," in which the 7th Division, which was following the North Korean 6th Division, took another diversion and attempted to attack in the direction of Tongyeong. With this, the North Koreans intended to break through the Nakdong River defenses and head for Pusan. However, the North Korean attack was ultimately thwarted by the Korean Navy and Marine Corps' Tongyeong Amphibious Operation. With a swift maneuver using the sea as a maneuvering space, the Navy and Marine Corps occupied key points first, creating an advantageous situation and fending off an attack by the North Korean 7th Division. The Navy and Marine Corps' Tongyeong Amphibious Operation finally thwarted the North Korean military's maneuver toward Honam, thus maintaining the Nakdong River defenses.
The Journal of the Convergence on Culture Technology
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v.10
no.2
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pp.419-427
/
2024
This study assessed the potential impact of gas leakage resulting from accidental damage to buried urban gas pipelines during perforating operation near subway construction sites. The risk of explosions due to ignition sources such as static electricity, arising from gas infiltrating the subway construction site through storm sewers and sewage pipes, was evaluated using the ALOHA program. The results of the threat zone calculation, which input various parameters of urban gas pipelines such as length, diameter, and pressure, indicated that the flammable area within the vapor cloud extended from 1.2 to 1.4 km (red zone), the blast area ranged from 0.8 to 1.0 km (yellow zone), and the jet fire extended from 45 to 61 m (red zone). This study demonstrates that within the flammable area of the vapor cloud, a specific combination of concentration and conditions can increase flammability. The blast area may experience explosions with a pressure of 1.0 psi, sufficient to break glass windows. In the event of a jet fire, high temperatures and intense radiant heat exposure lead to rapid fire propagation in densely populated areas, posing a high risk of casualties. The findings are presented in terms of the sphere of influence and threat zone ranges.
An anionic polyurethane dispersions (PUDs) were synthesized from the poly (tetramethylene glycol) (PTMG, Mw = 2000 g/mol), mixed isocyanate of dicyclohexylmethane-4,4'-diisocyanate $(H_{12}-MDI)$ and 4,4'-diphenylmethane diisocyanate (MDI), and dimethylol propionic acid (DMPA) as anionic site, following a prepolymer mixing process. Triethylamine (TEA) was used as a neutralization agent and the ethylenediamine (EDA) as the chain extender of the prepolymer. The effects of the DMPA molar ratio and aromatic diisocyanate content in the mixed isocyanate on the particle size and viscosity of PUD were studied. Also, the mechanical and thermal properties of the PUD cast films were discussed according to the molar ratio of DMPA and aromatic isocyanate content. It was found that the particle size and the viscosity of an anionic PUD decreased with increasing DMPA molar ratio but increased with increasing aromatic isocyanate (MDI) content in the mixed isocyanate at the constant DMPA content. Tensile strength of the PUD cast films increased and elongation at break decreased with increasing DMPA content at the constant mixed isocyanate molar ratios. In thermal degradation temperature of PUD cast films, the effect of DMPA contents was great but the effect of aromatic isocyanate contents at the low DMPA content was very slight respectively.
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