• 환경생물
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• 제22권2호
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• pp.321-328
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• 2004

The effects of Di (2-ethylhexyl) phthalate (DEHP) on the fourth instar larvae of Chironomus riparius were tested in the laboratory. Employing a waterreplacement exposure setup, chironomids were subjected to various concentrations. In the most treatments mortality reached a statistically significant difference from the control conditions. As DEHP concentrations were increased, the rates of emerged adults decreased. Sex ratio was unaffected with little deviation from a 1:1 relationship (except in 1 and $30\mu{g}\;L^{-1})$. The developmental stages was delayed at low concentration (0.3 and $1\mu{g}\;L^{-1})$. Generally the emergent period was different between males and females, and the first emergent day of males was faster than females. The body shape of female adults was larger than males. Differences between males and females were found in body volume, body length and body width. In addition, the body volume showed the significant difference between controls and treatments, and those especially well observed females.

• 한국방사선학회논문지
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• 제11권2호
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• pp.79-85
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• 2017

본 연구에서는 유방촬영검사에서 사전조사 관전압과 실제조사 관전압 편차에 따른 원인분석을 유방압박두께, 유방크기, 체질량지수와 연관하여 규명하고 개선책을 찾고자 하였다. 국민건강보험공단에서 실시하는 유방촬영 검진자 중 40세 이상 여자 377명을 대상으로 조사하였다. 유방촬영검사에서 상하방향촬영에 의한 영상을 참고하여 의료영상저장정보시스템으로 전송되어진 선량 보고서(dose report)의 파라메타 중 사전조사 관전압과 실제조사 관전압의 편차에 따른 유방압박두께, 유방크기, 체질량지수를 분석하였다. 결과로는 유방압박두께가 얇을수록, 유방크기가 작을수록, 체질량지수가 작을수록 관전압 편차가 크게 나타났다. 결론적으로 유방촬영검사에서 유방압박두께와 유방크기에 따른 관전압 설정을 하기 위해 우리나라 실정에 맞는 유방촬영기기의 최소 관전압이 재설정 되어야 할 것이며, 또한 유방압박두께가 얇은 환자나 유방크기가 작은 환자를 검사할 경우 정확한 조사조건 매뉴얼을 만들어 검사함으로서 촬영조건의 편차를 줄여 방사선피폭 경감과 좋은 영상의 화질을 만드는데 노력해야 할 것으로 사료된다.

• 생명과학회지
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• 제25권2호
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• pp.151-157
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• 2015

Zebrafish는 약리학 연구에 널리 사용되는 실험 동물 중 하나이다. Oxytetracycline은 넓은 항균 범위를 가지는 항생제로써 단백질 합성을 억제하여 정균 작용을 가진 항생제이다. 본 연구의 목적은 OTC에 노출이 되었을 때 zebrafish에게서 나타나는 행동변화와 내분비계의 변화를 관찰하였다. OTC (50, 100 or 200 mg/l)에 노출된 zebrafish의 행동변화를 확인하기 위해 novel tank test와 open field test를 진행하였다. 또한 내분비계의 변화를 확인하기 위하여 whole-body cortisol의 수치를 cortisol kit를 이용하여 측정하였다. Novel tank test 결과 상층부에서 머문 시간과 부동 시간에서 OTC를 약욕하였을 때 통계적으로 유의성이 있는 증가현상이 확인되었다. 반면에, 총 이동거리, 과행동 시간, 유영 속도 그리고 상하 변위에서 OTC를 약욕하였을 때 통계적으로 유의성 있는 감소 현상이 확인되었다. Open field test 결과 부동시간에서 OTC를 약욕 하였을 때 통계적으로 유의성 있는 증가 현상이 확인 되었다. 그러나 OTC를 약욕 하였을 때 총 이동거리, 움직인 시간, 유영 속도에서 통계적으로 유의성이 있는 감소 현상이 확인 되었다. Whole-body cortisol에서는 zebrafish에게 약욕을 하였을 때 증가하는 경향이 관찰되었다. 이러한 결과를 통하여 OTC가 zebrafish에게 화학적 스트레스로 작용한 것으로 사료된다.

• 성인간호학회지
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• 제22권5호
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• pp.466-476
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• 2010

Purpose: The purpose of this study was to examine the under-reporting rate and related factors after blood and body fluid (BBF) exposure among hospital employees. Methods: Fifteen hundred l employees were conveniently sampled from ten university and acute care hospitals. The survey questionnaire consisted of 37 items. Data were collected from September 10 to November 30, 2008. Results: The survey response rate was 88.7%. The 47.9% (638/1,331) of hospital employees were exposed to BBF and the mean number of exposure was $4.7{\pm}5.942$ within the previous year. Under-reporting rate after BBF exposure was 69.4% (443/638). By multi-variate logistic regression analysis, the exposure number, exposure type, infectious disease and hospital were independently related to the under-reporting of BBF among hospital employees. Conclusion: The under-reporting rate after being exposed to blood and body fluids was relatively high. To address this problem, educational programs are needed to decrease the under-reporting rate for healthcare workers. Further, it might be helpful if other factors related to under-reporting be investigated in future studies.

• The Korean Journal of Physiology and Pharmacology
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• 제2권6호
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• pp.677-685
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• 1998

To investigate the effects of neonatal stress on behavior and neurochemistry, rats were exposed to the footshock stress on postnatal day (PND) 14 or PNDs 14 and 21. Rats were exposed to uncontrollable electric shocks delivered to the floor with a constant current (0.8 mA) for 5 sec period. Daily sessions consisted of 60 trials on a random time schedule with an average of 55 sec. The first exposure to footshocks on PND 14 decreased body weight gain for 1 day. However, the second exposure to footshocks on PND 21 did not affect body weight gain. Exploratory activity was measured by exposing a rat to a novel environment 24 h after experience of footshocks. Similar to the body weight changes, a decreased activity was noted after the first exposure to footshocks, while no changed activity was noted after the second exposure to footshocks. However, the Bmax value of $5-HT_{2A/2C}$ receptors in the cortex decreased by the second exposure to footshocks, but not by the first exposure to footshocks. Moreover, an autoradiographic study revealed that the density of $[^3H]dexamethasone$ binding in hippocampus decreased in rats exposed to footshocks 4 times during PND $14{\sim}20.$ These results suggest that the uncontrollable footshock stress changes 5-hydroxytryptamine and glucocorticoid receptor systems acutely and that the repeated exposure to the same stress may not elicit behavioral alterations by the compensatory activity of young brain although changes in some neurochemistry exist.

• 한국환경보건학회지
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• 제44권4호
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• pp.370-379
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• 2018

Objectives: Bisphenol A (BPA) has been extensively used in a variety of consumer products, resulting in widespread non-occupational human exposure. It is often detected in the human body. Studies have reported many health effects associated with endocrine and metabolic disruptions, including obesity, diabetes, hypertension, and cardiovascular diseases. This study was performed to explain the relationship between BPA exposure and obesity in the Korean adult population. Methods: The second stage of the Korean National Environmental Health Survey (KoNHES) was conducted from 2012 to 2014 with 6,478 persons participating. Using the results of the survey, we analyzed the exposure levels for BPA and the influence on obesity of BPA. Results: In model 1, the volume-based measure concentration of BPA, total, female and the 30s to 60s age group were positively related with BMI. In model 2, creatinine adjusted as a covariate and positive associations for BPA with BMI were observed in the female group and was marginally significantly associated in low body weight group. In model 3, creatinine adjusted (g/g-creatinine), BPA exposure, and BMI were positively related with sex, in females, and there was a marginally significant association with the low body weight group in the BMI categories. BMI was significantly associated with BPA in the female group in all three models. Conclusion: This study added further evidence that exposure to EDCs, include bisphenol A, is related with obesity among the general population. Given the environmental health concerns over BPA, it is necessary to develop comprehensive measures to reduce BPA exposure.

• Journal of Trauma and Injury
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• 제25권4호
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• pp.241-246
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• 2012

Purpose: The objective of this study was to investigate the appropriateness of the cross table lateral cervical X-ray used in the emergency department for severely traumatized Korean patients. Methods: Patients visiting our institution from May 2011 to May 2012, who had injury severity score (ISS) > 15 and who received a cervical X-ray in the emergency department, were included in this study. Data including demographics, ISS score, GCS score, and place where the x-ray was taken were collected to evaluate their relationship with appropriate coverage of the cervical X-ray. The appropriateness of a cervical cross lateral view X-ray was evaluated using exposure of the basion, and the opisthion, as well as the distal level of exposure. Results: Fifty-two patients were included in this study. The identification rate of the basion was 79.2%, and the identification rate of the opisthion was 88.7%. Complete exposure of C7/T1 was accomplished in 3.8% of the patients. The ISS was higher for X-ray taken in the trauma bay, but the range of exposure showed no difference between the places where the X-rays taken. Patients who had exposure of C 5/6 or more had lower body weight and body mass index (BMI) compared with unexposed patients. Conclusion: In severely traumatized Korean patients, the adequacy of the cross table lateral cervical X-ray was inappropriate in most cases. No difference was observed in the exposure range between the places where the X-rays were taken, and patients with less exposure showed higher body weight and higher BMI.

• Safety and Health at Work
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• 제5권1호
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• pp.17-22
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• 2014

Background: Health care professionals (HCPs) are at high risk of contracting blood-borne infections due to their occupational exposure to blood and body fluids (BBFs). The incidence of these infections among HCPs are higher in low income countries such as Ethiopia. The aim of the study was to investigate the extent of occupational exposure to BBFs and its associated factors among HCPs in Bahir Dar town, Ethiopia. Methods: A cross-sectional study was used from October 1, 2012 to October 30, 2012. Three hundred and seventeen HCPs were included in the study using a simple random sampling technique. The data were collected using a structured questionnaire and analyzed using SPSS version 16. Bivariate and multivariate analyses were used to identify the factors related to exposure to BBFs. Results: Two hundred and nine (65.9%) HCPs were exposed to BBFs in the past year, of which 29.0% were needlestick injuries. Work experience [adjusted odds ratio (AOR) 4.13, 95% confidence interval (CI) 1.56-10.91], inconsistent use of gloves (AOR 1.98, 95% CI 1.04-3.43), and not complying with standard precautions (AOR 1.80, 95% CI 1.00-3.22) were the factors associated with occupational exposure to BBFs. Conclusion: A high proportion of HCPs was exposed to BBFs in this study. Occupational exposure to BBFs was determined by the use of gloves and not complying with standard precautions. Ensuring the availability of gloves, training about standard precautions, and motivation of HCPs to implement standard precautions should be emphasized to avoid such exposures.

• Journal of Radiation Protection and Research
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• 제34권2호
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• pp.55-64
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• 2009

In a pressurized heavy water reactor (PHWR), radiation workers who have access to radiation controlled areas submit their urine samples to health physicists periodically; internal radiation exposure is evaluated by the monitoring of these urine samples. Internal radiation exposure at PHWRs accounts for approximately 20 $\sim$ 40% of total radiation exposure; most internal radiation exposure is attributed to tritium. Carbon-14 is not a dominant nuclide in the radiation exposure of workers, but it is one potential nuclide to be necessarily monitored. Carbon-14 is a low energy beta emitter and passes relatively easily into the body of workers by inhalation because its dominant chemical form is radioactive carbon dioxide ($^{14}CO_2$). Most inhaled carbon-14 is rapidly exhaled from the worker's body, but a small amount of carbon-14 remains inside the body and is excreted by urine. In this study, a method for dual analysis of tritium and carbon-14 in urine samples of workers at nuclear power plants is developed and a method for internal dose assessment using its excretion rate result is established. As a result of the developed dual analysis of tritium and carbon-14 in urine samples of radiation workers who entered the high radiation field area at a PHWR, it was found that internal exposure to carbon-14 is unlikely to occur. In addition, through the urine counting results of radiation workers who participated in the open process of steam generators, it was found that the likelihood of internal exposure to either tritium or carbon-14 is extremely low at pressurized water reactors (PWRs).

• 한국의류학회지
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• 제28권11호
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• pp.1395-1403
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• 2004

Exposure and Concealment have been continued as important way to express fashion and theme as well, especially in women fashion. Exposure can make themselves attractive, and concealment emphasizes this way of being attractive by exposure. Besides the temptable effect of exposure, the ideology which put women next men in society has made a prominence on the fact exposure is significant theme in women fashion. It means that women's image of 'Being seen as Object' (this can be explained by relation passive between active) in society has driven female emphasize in using and focusing on exposure to be attractive. Also the other important thing in women fashion has been considered is concealment. The fact that society has demand women more chaste duty in detail may have meaningful thing in the condition that instigates women take off being attractive to the subject, considering ideology, men. Therefore attractive femininity has to be suggested by virtue and temptation, it is common sense that looking just shallow or too strict are far from criteria of ideal beauty. Namely, the concept for exposure coexists with concealment not only constructively but also naturally in fashion. Technique that can be accentuate for effective exposure differently from method to show unilaterally is needed, and this technique can promote new fashion. And according to the theory of Freud, women means' Absence (lacking penis)', this female's Lack Image induces male castration complex therefore 'Fetishistic Look' which transfers something phallic into specific things or parts of body is adopted, sort of object cathexis. This is revealed as some parts of women body are diverted into object for sexual love, symbolic equivalent. For example, women's parts like legs or breast are remarked as erotogenic zone and as time goes, when no more the zone are felt sexual by exposure, other somewhere felt mysterious (felt something sexual) used to be stressed by exposing. As it were, it can be possible that exposing part on women body (sexual part) moved as time passed because of what previously stated. Especially, the concept of exposure and concealment in women fashion should explain not only from a point of view of style for the beautifulness but also from wearer's immanent intention, further more relationship with ideology. About the present situation becoming bolder in women fashion, it is said that women express confidence as the position of women is elevated higher socially, the more women get freedom. But if we consider this psychoanalysis opinion mentioned ahead, the possibility can not be excluded that the exposure can get emphasizing according as the need of feminine modesty gets decreasing from ideal femininity society, men want. This study about exposure and concealment was made progressed through the theory of Freud who originated psychoanalysis, presented many theories. But nowadays contradictions are being brought up against Freud's theory including conventional philosophy like male chauvinism and adjust studies get suggested. Hereupon, there may be limitation in making no allowance of contradiction and following his theory.