• Journal of Society of Preventive Korean Medicine
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• v.17 no.3
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• pp.91-102
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• 2013

Objective : This study aimed to evaluate the relation ship between depression and anxiety, self esteem, BMI, blood types, blood pressure, scoliosis of spine. Method : We analyzed the results Health examination of 5619 university students (included BDI, BAI, SES, BMI, Blood Types, Blood Pressure, X-ray of whole spine). All the data were analyzed statistically by descriptive statistics, t-test, ANOVA and regression analysis. Result : Female's BMI score and BAI score are higher than Male's. And Senior Group showed higher score than Freshman Group. There were positive correlation between BAI, and BDI. but negative correlation between SES, Blood Pressure and BDI. BMI, Blood types and Scoliosis of spine were not related to depression. Conclusion : There were correlation between BAI, SES, Blood Pressure and BDI. It is necessary to study about depression with many other effective factors of various psychological and physical subjects.

• Design & Manufacturing
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• v.12 no.2
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• pp.57-62
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• 2018

In diabetics, daily blood glucose testing is generally required at home, and thus, performing blood collection several times a day using a blood line is essential. Blood collection in the home and in the hospital is a source of pain and is the second most common cause of infection. In blood collecting device generally consists of four major parts: inner-case, outer case, main shaft and triger, and the most import part among those for necessary functionality is the main shaft. Filling time and injection pressure, filling balance, strain-rate analysis of change based on availability of the product. The Moldflow of FEM simulation is used for the analysis of injection molding process. In this study, aims to create a technique for injection molding and manufacturing of a main shaft of a high-performance blood-collecting apparatus capable of automatically extracting a lancet to relieve pain through depth control of the lancet.

• The Journal of the Korea Contents Association
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• v.15 no.3
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• pp.272-279
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• 2015

Recently, studies about various natural extracts to help control blood glucose has been in progress. Avena sativa is well known to have various physilogical effects. Especially, ${\beta}$-glucan has effect about lowering blood glucose level and prevent cardiovascular dz and adult dz related to obesity. In this study we evaluated the effect of Down and control (BM pharmaceutical) which is consist of commercialized Avena sativa fextracts on blood glucose and cholesterol, 6weeks, randomized, double-blind, placebo-controlled trials. The results show not significantly different in all blood index test group from control group, but in glycated albumin decreased 50.33% for test group, decreased 37.91% for control group, in triglyceride decreased 7.51% for test group, increased 3.98 for control group and we can observed Avena sativa has blood glucose and triglyceride lowering effect in some.

• Journal of Korean Academy of Nursing
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• v.28 no.4
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• pp.980-991
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• 1998

The purpose of this study was to examnin the effect of slow stroke back massage(SSBM) on anxiety and immune response in patients undergoing open heart surgery and to compare the effect of 5-minutes with 10-minutes SSBM. Among the sixty-four patient subjects, twenty-one were one experimental group receiving massage for 10-minutes, twenty for the other experimental group receiving massage for 5-minutes and twenty-three for the control group. Subjects were admitted at Hospitals in Inchon and Puchon for open heart surgery. This study was carried out from October 10, 1997 to May 10, 1998. The levels of anxiety were measured by the Visual Analogue Scale(VAS), Trait anxiety scale, systolic and diastolic blood pressure, pulse rate, blood cortisol and the levels of immune response were measured by the blood T-lymphocyte and Natural killer cell. Study measurements were taken before and after SSBM on the 1st post operative day. Data were analyzed using x$^2$ test, oneway ANOVA, paired t-test, t-test and Pearson product moment correlation. The results were summarized as follows : 1. After SSBM, VAS anxiety level, systolic and diastolic blood pressure and pulse rate of the experimental group were decreased significantly than those measurements before the SSBM. After SSBM, significant difference in the VAS anxiety level, systolic blood pressure and pulse rate between the experimental and control groups were found. 2. After SSBM, the blood cortisol of the experimental and control groups were increased significantly compared with before SSBM. But the significant difference in blood cortisol between the two groups was not found. 3. After SSBM, the blood T-lymphocyte percentages of the experimental and control groups were decreased signigicantly and blood Natural killer cell percentages of the two groups were increased compared with before SSBM. But significant difference in blood T-lymphocyte and Natural killer cell percentages between the two groups was not found. 4. Significant difference in VAS anxiety level, systolic and diastolic blood pressure, pulse rate, blood cortisol, blood T-lymphocyte and Natural killer cell percentages between SSBM for 5 minutes and SSBM for 10 minutes were not found. Based upon the results, this study concludes that the slow stroke back massage for 5 minutes is a useful intervention that decreases anxiety and produces relaxation in patients undergoing open heart surgery.

• Journal of Digital Convergence
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• v.12 no.12
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• pp.405-415
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• 2014

The purpose of this study is to investigate the knowledge and recognition about blood donation and satisfaction, look for ways to promote the idea that effective, was trying to get the plan to provide the basis for the expanding population of voluntary and continuous blood donation. A survey was from May 9, 2012 to May 24, 2012 and total 636 copies were used as final study data. The data collected analyzed with SPSS win 21.0 using descriptive methods, frequency analysis, chi-square test, t-test, ANOVA. The results were as follows. First, the rates of the blood donors were higher in the men, in the age group from 20 to 29, in the students and in the group that received college or higher education. Second, as for the knowledge and recognition of the blood donors on blood donation, many replied they didn't know well about it. Concerning satisfaction level, they gave higher marks to satisfaction with related service than with blood donation itself. Third, the necessity of sustained blood donation promotion and education was pointed out. TV was most preferred, followed by ads on the street and ads on the subway. To expedite an increase in the blood-doner population, prolonged education and promotion are required to change the way that people in general look at blood donation, and a variety of rewards should be provided for blood donors.

• Journal of Microbiology and Biotechnology
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• v.25 no.2
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• pp.255-267
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• 2015

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic debilitating disease affecting ruminants worldwide. In the present study, we aimed to determine the major gene networks and pathways underlying the immune response to MAP infection using whole-blood cells, as well as provide the potential transcriptional markers for identifying the status of MAP infection. We analyzed the transcriptional profiles of whole-blood cells of cattle identified and grouped according to the presence of MAP-specific antibodies and the MAP shed by them. The grouping was based on the results obtained by ELISA and PCR analyses as follows: i) Test1 group: MAP-negative results obtained by ELISA and positive results obtained by PCR; ii) Test2 group: MAP-positive results obtained by ELISA and negative results obtained by PCR; iii) Test3 group: MAP-positive results obtained by ELISA and positive results obtained by PCR; iv) uninfected control: MAP-negative results obtained both by ELISA and PCR analysis. The results showed down-regulated production and metabolism of reactive oxygen species in the Test1 group, activation of pathways related to the host-defense response against MAP (LXR/RXR activation and complement system) in the Test2 and Test3 groups, and anti-inflammatory response (activation of IL-10 signaling pathway) only in the Test3 group. Our data indicate a balanced response that serves the immune-limiting mechanism while the host-defense responses are progressing.

• Korean Journal of Agricultural Science
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• v.11 no.2
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• pp.303-314
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• 1984

In order to study the safety of ginseng ingested as a food substance, rats were fed ginseng added feed (subgroup 1: 0.625g/kg feed; subgroup 2: 1.25g/kg feed; subgroup 3: 2.5g/kg feed) for periods up to 6 months. Growth rates, blood composition, blood cell counts, and histopathological studies were carried out on both the control and test animals to study the effect of ingested ginseng. Following results were obtained: 1. The growth rates of the test and control animals were similar with the exception of the subgroup 3 in the 2-month fed animals who had a lower weight gain, and the subgroup 2 in the 4-month fed group who had a higher weight gain than the controls. 2. Liver, spleen, kidney, brain, lung and heart weights were similar between the test and the controls. 3. RBC, WBC, hematocrit, and hemoglobin values were similar between the test and control animals. the blood composition determination showed a similar level of alkaline phosphatase, triglyceride, total cholesterol, S-GOT, free cholesterol between the test and controls. However, free fatty acid, total lipid and S-GPT levels decreased while phospholipid, total protein, and HDL-cholesterol levels tended to increase. 4. Fl, F2 generations showed no abnormai values in blood count, organ weight and external appearance. 5. No histopathological differences were observed between the test and control animals even after a long-term administration of ginseng. However, there was evidence that ginseng promotes hematopoiesis in test animals. 6. These results suggest that ginseng is not only safe as a food substance but may indeed strengthen the body and help-prevent diseases of old age.

• Archives of Plastic Surgery
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• v.38 no.4
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• pp.369-375
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• 2011

Purpose: Many hemostatic agents and dressings have been tested with variable degree of success. Chitosan has a positive charge, it attracts red blood cells, which have a negative charge. Our goal is to test the efficacy of new developed chitosan-based hemostatic materials in providing durable hemostasis in a high-flow arterial wound model. Methods: We compared each group with SD rats motality tests and in vitro blood compatibility test by blood clotting index (BCI). We devided the SD rats into 6 groups (N =15) by type of hemostatic agents. A: 100% nonwoven chitosan (degree of the deacetylation: 90%). B: 50% N-acetylation on nonwoven of chitosan gel (degree of the deacetylation: 50%). C: 60% N-acetylation on nonwoven of chitosan ge (degree of the deacetylation: 40%)l. D: Cutanplast$^{(R)}$. E: HemCon$^{(R)}$ F: Gauze. In vivo test, a proximal arterial injury was created in unilateral femoral arteries of 90 anesthetized SD rats. Each materials was made same size and thickness then applied to the injury site for 3 minutes. In vitro test, we compared each group with BCI in human blood. Results: In vivo test, group A showed lower motality rate of 46% than any other groups, Group B and C showed lower motality rate of 60% than group D and E's motality rate of 66%. In vitro test, BCI of group A ($30.6{\pm}1.2$) and B ($29.3{\pm}1.0$) were showed nearly about group D ($29.1{\pm}1.8$) and E ($27.4{\pm}1.6$). Group C ($37.1{\pm}2.0$) showed higher BCI than group A and B, it means group C decreased blood clotting. Conclusion: In conclusion, this study suggests a newly developed chitosan-based hemostatic materials induced durable hemostasis and increased blood clotting, and are considered as effective biologic hemostatic agents.

• Proceedings of the KOSOMBE Conference
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• v.1991 no.05
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• pp.89-93
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• 1991

The purpose of this reserch is to design the blood cell counting instrument which can measure the number of RBC(Red Blood Cell) and WBC(White Blood Cell) including many other blood component. The proposed method uses the electrical impedence method and the new discrimination method wi th DSP chip and software algorithm. The system consist of control unit, blood cell discrimination unit, hemoglobin spectrometer, post detect ion processor unit, and IBM-PC interface unit. In this paper, the discrimination system has been implemented using digital signal processor, which result in the reduction of system hardware and cost. The system is helpful in providing necessary clinical test for screen test and quality control of hematology.

• Biomedical Science Letters
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• v.16 no.1
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• pp.25-32
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• 2010

Sprague-Dawley(SD) rats were orally administered with $N^G$-nitro-L-arginine methyl ester(L-NAME) which inhibits or blocks the production of nitric oxide from L-arginine in vascular endothelial cells and vessel tissue to statistically examine the effects of nitric oxide on some physiological changes such as blood pressure and heart rate, and to confirm the apoptosis induced by the suppressed nitric oxide activity in some related organs under light microscope. Systolic blood pressure significantly increased 28.5% by the chronic treatment of L-NAME for 8 weeks (P<0.001), no significant difference, however, was observed in heart rate between the control group and the L-NAME-treated group regardless of their age. Hematoxylin-eosin staining showed some histological alterations only in kidney among the examined organs; heart, liver, pancreas, and adrenal gland from the L-NAME-treated group. TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) test showed a strong positive reaction, representing that the chronic treatment of L-NAME facilitates apoptosis, in the cortex and medulla of kidney, but not any significance detectable in the other organs. These results conclude that chronic treatment of L-NAME significantly increases blood pressure, and that the followed inhibition of nitric oxide synthesis occurs a typical inducement of apoptosis in kidney.