• 대한조선학회논문집
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• 제55권4호
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• pp.330-340
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• 2018

In the present works, the High-speed Cavitation Tunnel (HCT) has been designed and manufactured to have the large test section to conduct various supercavitation experiments. The large amount of air ventilated behind a cavitator produces lots of tiny bubbles, which prevent clear observation of supercavitation at the test section. To collect small bubbles effectively, a bubble collecting section of large volume is equipped upstream of the test section. HCT has the test section dimension of $0.3^H{\times}0.3^W{\times}3.0^L\;m^3$ and provides maximum flow speed of 20.4 m/s at the test section. The blockage and Froude effects on the ventilated supercavitation are investigated successfully at the test section. The basic studies such as the supercavitation evolution, drag measurements and cavity shape extraction with air flow rate are also carried out in HCT.

• Journal of Advanced Marine Engineering and Technology
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• 제39권9호
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• pp.947-952
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• 2015

현재 우리나라의 에너지 부족 문제를 해결하기 위하여 정부 주도로 다양한 산악지형에서 풍력발전단지가 건설되고 있다. 하지만 무분별하게 풍력발전단지를 건설 할 경우, 풍력발전기의 도플러 변조로 인하여 주변에 운용되고 있는 군사레이더에 심각한 방해 현상을 야기하여 국가 안보에 심각한 위협이 될 수 있다. 따라서 풍력발전기 작동을 고려한 레이더 신호분석 및 도플러 주파수 분석이 필요하다. 본 논문에서는 이러한 산악지형에 설치된 풍력발전단지로 인한 도플러 주파수 추출 및 분석을 위한 신호처리 기법을 제안한다. 제안된 기법은 산악지형 모델링, 차폐분석, 풍력발전기 운동 모델링 및 레이더 신호 모델링을 기반으로 한 방법이며, 시뮬레이션 결과 산악지형의 형태 및 풍력발전기의 운동에 따라 시변 하는 도플러 주파수를 추출되었다.

• 한국지반공학회논문집
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• 제38권11호
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• pp.7-17
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• 2022

본 연구에서는 중력식 사방댐 후면에 설치된 원통형 강성기둥 구조물의 배치변화가 토석류의 흐름거동 및 충격하중 변화에 미치는 영향을 확인하기 위해, 대책구조물들을 소형수로에 모사한 다음 원통형 구조물의 종방향 배열 수와유로 차단비율을 변화시켜가면서 실내모형실험을 수행하였다. 실험과정에서 대책구조물의 주변 흐름거동을 촬영하고, 중력식 사방댐의 작용하는 토석류의 충격하중을 측정하기 위해, 수로 측면과 상부에는 고속카메라를 설치하였고, 사방댐의 전면에는 로드셀을 설치하였다. 게다가, 글라스 비즈를 이용하여 토석류에 의해 동반되는 큰 직경의 거석들을 수로에 모사하였다. 실험결과, 중력식 사방댐 후면에 원통형 강성기둥 구조물의 설치는 토석류의 충격하중을 크게 감소시키는 것으로 나타났다. 또한, 대책구조물의 유로 차단비율을 증가시키면 거석을 동반한 토석류의 흐름억제를 증가시켜 충격하중을 더욱 감소시키는 것으로 나타났다.

• ETRI Journal
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• 제35권5호
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• pp.775-785
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• 2013

Because of their exclusive features, millimeter wave directive mesh networks can be considered for small cell backhaul support in urban environments. For this purpose, a network of closely spaced stations has been considered with very directive line-of-sight links operating in the 60-GHz band. An attempt is made to evaluate channel response and interference behavior in such a network, taking into account the effect of building blockage. A simple grid of building blocks is considered as the propagation environment, and wave propagation is simulated using 2.5-dimensional (2.5D) ray tracing (2D with ground effect) to calculate the received signal at different nodes in the network. The results are compared with free space predictions and used to evaluate interference at all nodes in the channel and describe certain characteristics of links, such as the delay profile and the correlation length.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2002년도 유체기계 연구개발 발표회 논문집
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• pp.111-115
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• 2002

The objective of this work is to develop improved slip factor model and correction method to predict flow through impeller in forward-curved centrifugal fan by investigating the validity of various slip factor models. Both steady and unsteady three-dimensional CFD analyses were performed with a commercial code tn validate the slip factor model and the correction method. The results show that the improved slip factor model presented in this paper could provide more accurate predictions for forward-curved centrifugal impeller than the other slip factor models since the presented model takes into account the effect of blade curvature. The comparison with CFD results also shows that the improved slip factor model coupled with the present correction method provides accurate predictions for mass-averaged absolute circumferential velocity at the exit of impeller near and above the flow rate of peaktotal pressure coefficient.

• Archives of Pharmacal Research
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• 제25권4호
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• pp.500-504
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• 2002

Propolis, obtained from honeybee hives, has been used in Oriental folk medicine as an anti-inflammatory, anti-carcinogenic, and immunomodulatory agent. There is considerable evidence suggesting that angiogenesis and chronic inflammation are codependent. Blockage of angiogenesis results in an anti-inflammatory effect. Ethanol (EEP) and ether extracts of propolis (REP), and caffeic acid phenethyl ester (CAPE), an active component of propolis, were examined for their anti-angiogenic activities using the chick embryo chorioallantoic membrane (CAM), and the calf pulmonary arterial endothelial (CPAE) cell proliferation, assays. The presence of EEP, REP and CAPE inhibited angiogenesis in the CAM assay and the proliferation of CPAE cells. The results suggest that anti-angiogenic activities of EEP, REP and CAPE are also responsible for their anti-inflammatory effect.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2006년도 하계학술발표대회 논문집
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• pp.132-137
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• 2006

Supercooled type ice slurry system is hard to keep a proper supercooling degree when solution becomes supercooling state. This is the reason of the ice blockage in pipe or cooling part due to an unstable cooling state. In this study, a cooling experiment was performed to pressurized solution in a stationary state. The behaviors during the supercooled aqueous solution were investigated at fixed flow rate of brine and aqueous solution of ethylene glycol 7 mass%. Also the effect to the freezing point of supercooled aqueous solution was investigated to the different pressure 101, 202, 303, and 404 kPa. At results, the pressure of the aqueous solution in the cylinder increased the supercooling degree increased and dissolution of supercooled point decreased.

• 한국환경과학회:학술대회논문집
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• 한국환경과학회 2020년도 정기학술대회 발표논문집
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• pp.219-219
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• 2020

Kaempferol (3,4',5,7-tetrahydroxyflavone), a flavonoid found in beans, broccoli, garlic, etc., has been used in natural medicine as an anti-inflammatory and antioxidant. This experiment was carried out to evaluate the anti-apoptotic effect of kaempferol in 12-O-tetradecanoylphorbol 13-acetate (TPA)-treated Normal Human Dermal Fibroblast (NHDF). Kaempferol inhibited the production of intracellular Reactive Oxygen Species (ROS) induced by TPA in NHDF. Kaempferol significantly blocks the phosphorylation of extracellular signal-regulated kinase responsible for the activation of nuclear factor-kappa B. In addition, kaempferol significantly attenuated the expression of Bax and cleaved caspase-3 as regulated by the phosphorylation of nuclear factor-kappa B during its blockage of TPA-induced apoptotic cell death. These findings suggest that kaempferol protects the apoptotic signaling pathway induced by TPA through modulating intracellular ROS in NHDF.

• The Korean Journal of Pain
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• 제21권3호
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• pp.202-205
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• 2008

Background: Lumbar radicular pain is a frequent and often debilitating event. Although many treatment methods have been described in several studies, the available evidences regarding efficacy is not sufficient enough to draw definitive conclusions on an optimal therapy regime. Pulsed radiofrequency (RF) treatment was found to exert a beneficial effect on intractable radicular pain in individuals. The purpose of this study was to assess the efficacy of pulsed RF of the dorsal root ganglion for chronic lumbar radicular pain. Methods: Twenty five patients with chronic lumbar radicular pain that was refractory to selective nerve root blockage met the inclusion criteria of our study and received pulsed RF treatment. The average numeric rating scale (NRS) for leg pain during usual activities and the Oswestry disability index (ODI) were measured at 1 and 3 months after the procedure. Results: Of the 25 patients accepted for pulsed RF treatment, one dropped out due to a vertebral compression fracture during this study. ODI and NRS showed a positive trend in favor of the pulsed RF treatment. No significant complications were observed during the study period. Conclusions: It appears that pulsed RF treatment of the lumbar spinal dorsal root ganglion may be an effective treatment method for patients suffering from lumbar radicular pain, and who were not responsive to selective nerve root blockage.

• 대한한방내과학회지
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• 제29권1호
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• pp.243-257
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• 2008

Myostatin, a negative regulator of myogenesis, is shown to function by controlling the proliferation of myoblasts. In this study we show that myostatin is an inhibitor of myoblast differentiation and that this inhibition is mediated through Smad 3. To determine MyoD expression by Dodamtang treatment, we compared the expression pattern of $C_{2}C_{12}$ mouse myoblasts that constitutively express myostatin with control cells. In vitro, increasing concentrations of Dodamtang reversibly prevented the myogenic blockage of myoblasts by myostatin expression. ELISA assay, Western and confocal analysis indicated that treatment of Dodamtang to the low serum culture media increased the levels of MyoD leading to the inhibition of myogenic differentiation by myostatin. The stable transfection of $C_{2}C_{12}$ myoblasts with myostatin expressing constructs did rescue MyoD-induced myogenic differentiation. Consistent with this, the treatment of Dodamtang rescued the expression of a MyoD in $C_{2}C_{12}$ myoblasts treated with myostatin. Taken together, these results suggest that induction of MyoD by Dodamtang inhibits myostatin activity and expression via SMAD3 resulting in the rescue of the myoblasts to differentiate into myotubes. Thus we propose that myostatin action by Dodamtang plays a critical role in myogenic differentiation and that the muscular hyperplasia and hypertrophy seen in animals that blockage of functional myostatin is because of deregulated proliferation and differentiation of myoblasts.