• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2008년도 Techno-Fair 및 추계학술대회 논문집 전기물성,응용부문
• /
• pp.184-184
• /
• 2008

This paper presents the measurement of the mechanical property of PDMS (Polydimethylsiloxane) elastomer depending on volumetric mixing ratios of base polymer and curing agent and their hyperelastic material models.

• 한국동물학회:학술대회논문집
• /
• 한국동물학회 2003년도 한국생물과학협회 학술발표대회
• /
• pp.173.4-173
• /
• 2003

No Abstract, See Full Text

• Macromolecular Research
• /
• 제17권8호
• /
• pp.603-608
• /
• 2009

Novel ultra-high molecular weight polyethylene (UHMWPE)/zirconia composites were previously prepared by the in situ polymerization of ethylene using a Ti-based Ziegler-Natta catalyst supported on to the surface of zirconia, as a bearing material for artificial joints. Tribological tests revealed that a uniform dispersion of zirconia in UHMWPE markedly increased the wear resistance. The effects of zirconia content on the oxidation behavior of the ${\gamma}$-ray-treated UHMWPE/zirconia composite surfaces were examined. The oxidation index that estimates the oxidation degree as the content of total carbonyl compounds was monitored using Fourier transform infrared spectroscopy-attenuated total reflectance. The changes in the surface composition due to the oxidation were confirmed by electron spectroscopy for chemical analysis. The extent of oxidation decreased with increasing zirconia content, which was attributed to the increased crystallinity as well as the decreased polymer portion of the UHMWPE/zirconia composites.

• 대한의용생체공학회:의공학회지
• /
• 제28권3호
• /
• pp.344-347
• /
• 2007

A interpenetrating polymer network (IPN) hydrogel, composed of chitosan (CS) and poly(diallydimethylammonium chloride) (PDADMAC) was prepared, which exhibited electrical sensitive behavior. The swelling behavior of the CS/PDADMAC SIPN hydrogel was studied by immersion of the gel into various pH buffer solutions, and their stimuli response in electric fields also investigated. In order to clarify the relationship between the equilibrium swelling ratio and bending behavior of the SIPN hydrogels, the state of water in the SIPN hydrogel was also investigated using differential scanning calorimetry (DSC).

• Macromolecular Research
• /
• 제14권6호
• /
• pp.668-672
• /
• 2006

• 폴리머
• /
• 제34권6호
• /
• pp.547-552
• /
• 2010

생분해성 고분자는 제약 및 생명공학 분야에서 많은 관심을 받고 있는 물질로 특히 나노미립구의 형태로 약물전달체의 개발에 널리 이용되고 있다. 본 연구에서는 cyclohexanedimethanol과 oxalyl chloride를 pyridine의 존재 하에서 반응하여 고분자량의 생분해성 퍼옥살레이트 고분자를 합성하고 그 물리화학적 및 생물학적 특성을 조사하였다. 폴리옥살레이트는 분자량이 약 75000 Da 정도인 반결정성 고분자이며 물에서 가수분해가 일어남을 GPC와 NMR로 확인하였다. 소수성의 폴리옥살레이트는 단일유화법으로 나노미립구로 제조될 수 있으며 약물을 포접할 수 있고 아주 우수한 세포안정성을 가졌다. 용이한 합성과 우수한 물리화학적 및 생물학적 특성을 바탕으로 폴리옥살레이트 나노미립구는 약물전달체 개발에 아주 높은 잠재력이 있음을 확인하였다.

• 한국고분자학회지:고분자과학과기술
• /
• 제16권5호
• /
• pp.646-665
• /
• 2005

• 한국고분자학회지:고분자과학과기술
• /
• 제20권5호
• /
• pp.465-471
• /
• 2009

• 폴리머
• /
• 제29권5호
• /
• pp.518-521
• /
• 2005

생분해성 고분자와 수화젤의 약물 전달 시스템과 조직 공학을 포함하는 다양한 생의학적인 응용이 점차 확대되고 있다. 하이드록실 pendant group을 갖고 있는 폴리아미노산의 하나인 PHEA는 뛰어난 생분해성과 우수한 생체적합성을 갖는 고분자로 알려져 있다 PHEA 및 그 유도고분자를 제조하고 이를 다양한 생의학적인 응용에 적용하는 연구가 진행되어 왔다. 본 연구에서는 유기용매에서 가교제인 HMDI를 사용하여 PHEA 수화젤을 제조하였다. PHEA는 아스팔트산의 열 축중합에 의해 합성한 polysuccinimide와 ethanolamine과의 고분자 반응으로부터 제조하였다. 제조한 수화젤에 대한 서로 다른 수용액과 pH용액에서의 팽윤 거동을 조사하였고, SEM을 통한 수화젤의 모폴로지와 가수분해 거동을 관찰하였다.

• Macromolecular Research
• /
• 제12권2호
• /
• pp.219-224
• /
• 2004

In this work, we prepared hydrogels for wound dressing from a mixture of poly(vinyl alcohol) (PVA) and alginate using the $\^$60/Co ${\gamma}$-ray irradiation technique. We examined the physical properties of these hydrogels, including gelation, water absorptivity, and gel strength, to evaluate the applicability of these hydrogels for wound dressings. The biocompatibility of these hydrogels was also evaluated in vitro, in cultures of mouse fibroblasts, and in vivo, by subcutaneous implantation studies in rats. The gel content and strength increased upon increasing the radiation dose and upon decreasing the concentration of alginate. The degree of swelling was inversely proportional to the gel content and strength. The degree of cytotoxicity of the ${\gamma}$-ray-treated hydrogels was ca. 60% compared to the (－) control (serum) after 1 day of incubation. When the incubations were prolonged up to 2 days, the toxicity of all the samples decreased remarkably and reached that of the control. Subcutaneous implantation studies in rats indicated that foreign body reactions occurring around the implanted hydrogels were moderate and became minimal upon increasing the implantation time.