• Title/Summary/Keyword: Biological information

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Full-Length Enriched cDNA Library Construction from Tissues Related to Energy Metabolism in Pigs

  • Lee, Kyung-Tai;Byun, Mi-Jeong;Lim, Dajeong;Kang, Kyung-Soo;Kim, Nam-Soon;Oh, Jung-Hwa;Chung, Chung-Soo;Park, Hae-Suk;Shin, Younhee;Kim, Tae-Hun
    • Molecules and Cells
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    • v.28 no.6
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    • pp.529-536
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    • 2009
  • Genome sequencing of the pig is being accelerated because of its importance as an evolutionary and biomedical model animal as well as a major livestock animal. However, information on expressed porcine genes is insufficient to allow annotation and use of the genomic information. A series of expressed sequence tags of 5' ends of five full-length enriched cDNA libraries (SUSFLECKs) were functionally characterized. SUSFLECKs were constructed from porcine abdominal fat, induced fat cells, loin muscle, liver, and pituitary gland, and were composed of non-normalized and normalized libraries. A total of 55,658 ESTs that were sequenced once from the 5′ ends of clones were produced and assembled into 17,684 unique sequences with 7,736 contigs and 9,948 singletons. In Gene Ontology analysis, two significant biological process leaf nodes were found: gluconeogenesis and translation elongation. In functional domain analysis based on the Pfam database, the beta transducin repeat domain of WD40 protein was the most frequently occurring domain. Twelve genes, including SLC25A6, EEF1G, EEF1A1, COX1, ACTA1, SLA, and ANXA2, were significantly more abundant in fat tissues than in loin muscle, liver, and pituitary gland in the SUSFLECKs. These characteristics of SUSFLECKs determined by EST analysis can provide important insight to discover the functional pathways in gene networks and to expand our understanding of energy metabolism in the pig.

On-Line music score recognition by DPmatching (DP매칭에 의한 On-Line 악보인식)

  • 구상훈;이병선;김수경;이은주
    • Proceedings of the Korea Society of Information Technology Applications Conference
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    • 2002.11a
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    • pp.502-511
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    • 2002
  • 컴퓨터의 기술적 발전은 사회 여러 분야에 막대한 영향을 끼쳤다. 그중 악보 인식분야에도 커다란 영향을 주었다 그러나, On-line 상에서 그린 악보를 실시간으로 정형화된 악보형태로 변환하는 처리에 대한 연구가 미흡하여 이에 대한 연구가 필요하다. 본 논문에서는 실시간으로 악보를 인식하고, 사용자의 편의를 도모하기 위해 DP(Dynamic Programming) 매칭법을 이용한 On-Line 악보인식에 관한 방법을 제안하였다. 본 연구에서는 실시간으로 입력되는 악상기호를 인식하기 위해, 가장 유효한 정보인 악상 기호내의 방향, x, y 좌표를 이용하여 벡터형태로 추출한 후 음표와 비음표(쉼표, 기타기호)의 두개의 그룹으로 나누어진 표준패턴과의 DP매칭을 통해 인식한다. 먼저 tablet을 통해 실시간으로 악상 기호를 입력할 때 생기는 x, y좌표를 이용하여, 펜의 움직임에 대한 16방향 부호화를 수행한다. 음표와 비음표를 구분하기 위한 시간을 줄이고자 16방향 부호화를 적용하치 않고 사사분면부호화를 적용한다. 음표를 약식으로 그릴 경우 음표 머리에 해당하는 부분의 좌표는 삼사분면에 분포하고, 폐곡선의 음표일 경우에는 좌표가 사사분면에 고르게 나타난다. 폐곡선을 제외한 음표의 머리는 폐곡선과 같은 조건이면서 입력받은 y좌표값들 중에서 최소값과 최대값을 구한 다음 2로 나눈 값을 지나는 y좌표의 개수가 임의의 임계값 이상이면 음표로 판단한다. 위 조건을 만족하지 않을 경우 비음표로 취급한다. 음표와 비음표를 결정한 다음, 입력패턴과 표준패턴과의 DP매칭을 통하여 벌점을 구한다. 그리고 경로탐색을 통해 벌점에 대한 각각의 합계를 구해 최소값을 악상기호로 인식 하였다. 실험결과, 표준패턴을 음표와 비음표의 두개의 그룹으로 나누어 인식함으로써 DP 매칭의 처리 속도를 개선시켰고, 국소적인 변형이 있는 패턴과 특징의 수가 다른 패턴의 경우에도 좋은 인식률을 얻었다.r interferon alfa concentrated solution can be established according to the monograph of EP suggesting the revision of Minimum requirements for biological productss of e-procurement, e-placement, e-payment are also investigated.. monocytogenes, E. coli 및 S. enteritidis에 대한 키토산의 최소저해농도는 각각 0.1461 mg/mL, 0.2419 mg/mL, 0.0980 mg/mL 및 0.0490 mg/mL로 측정되었다. 또한 2%(v/v) 초산 자체의 최소저해농도를 측정한 결과, B. cereus, L. mosocytogenes, E. eoli에 대해서는 control과 비교시 유의적인 항균효과는 나타나지 않았다. 반면에 S. enteritidis의 경우는 배양시간 4시간까지는 항균활성을 나타내었지만, 8시간 이후부터는 S. enteritidis의 성장이 control 보다 높아져 배양시간 20시간에서는 control 보다 약 2배 이상 균주의 성장을 촉진시켰다.차에 따른 개별화 학습을 가능하게 할 뿐만 아니라 능동적인 참여를 유도하여 학습효율을 높일 수 있을 것으로 기대된다.향은 패션마케팅의 정의와 적용범위를 축소시킬 수 있는 위험을 내재한 것으로 보여진다. 그런가 하면, 많이 다루어진 주제라 할지라도 개념이나 용어가 통일되지 않고 사용되며 검증되어 통용되는 측정도구의 부재로 인하여 연구결과의 축적이 미비한 상태이다. 따라서, 이에 대한 재고와 새로운 방향 모색이 필요하다고 사료된다.로 사료되며, 임신관련 cytokine에 대한 다양한 연구가 요구되고 있다.₂/Hf(Variable)/Si 계에서 HfO₂ 박막이 Si 기판위에 직접 증착되면, 순수 HfO₂ 박막의

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Design of Low Power 4th order ΣΔ Modulator with Single Reconfigurable Amplifier (재구성가능 연산증폭기를 사용한 저전력 4차 델타-시그마 변조기 설계)

  • Sung, Jae-Hyeon;Lee, Dong-Hyun;Yoon, Kwang Sub
    • Journal of the Institute of Electronics and Information Engineers
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    • v.54 no.5
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    • pp.24-32
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    • 2017
  • In this paper, a low power 4th order delta-sigma modulator was designed with a high resolution of 12 bits or more for the biological signal processing. Using time-interleaving technique, 4th order delta-sigma modulator was designed with one operational amplifier. So power consumption can be reduced to 1/4 than a conventional structure. To operate stably in the big difference between the two capacitor for kT/C noise and chip size, the variable-stage amplifier was designed. In the first phase and second phase, the operational amplifier is operating in a 2-stage. In the third and fourth phase, the operational amplifier is operating in a 1-stage. This was significantly improved the stability of the modulator because the phase margin exists within 60~90deg. The proposed delta-sigma modulator is designed in a standard $0.18{\mu}m$ CMOS n-well 1 poly 6 Metal technology and dissipates the power of $354{\mu}W$ with supply voltage of 1.8V. The ENOB of 11.8bit and SNDR of 72.8dB at 250Hz input frequency and 256kHz sampling frequency. From measurement results FOM1 is calculated to 49.6pJ/step and FOM2 is calculated to 154.5dB.

Human Identification using EMG Signal based Artificial Neural Network (EMG 신호 기반 Artificial Neural Network을 이용한 사용자 인식)

  • Kim, Sang-Ho;Ryu, Jae-Hwan;Lee, Byeong-Hyeon;Kim, Deok-Hwan
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.4
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    • pp.142-148
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    • 2016
  • Recently, human identification using various biological signals has been studied and human identification based on the gait has been actively studied. In this paper, we propose a human identification based on the EMG(Electromyography) signal of the thigh muscles that are used when walking. Various features such as RMS, MAV, VAR, WAMP, ZC, SSC, IEMG, MMAV1, MMAV2, MAVSLP, SSI, WL are extracted from EMG signal data and ANN(Artificial Neural Network) classifier is used for human identification. When we evaluated the recognition ratio per channel and features to select approptiate channels and features for human identification. The experimental results show that the rectus femoris, semitendinous, vastus lateralis are appropriate muscles for human identification and MAV, ZC, IEMG, MMAV1, MAVSLP are adaptable features for human identification. Experimental results also show that the average recognition ratio of method of using all channels and features is 99.7% and that of using selected 3 channels and 5 features is 96%. Therefore, we confirm that the EMG signal can be applied to gait based human identification and EMG signal based human identification using small number of adaptive muscles and features shows good performance.

Analysis of River Disturbance using a GIS (I) (GIS기법을 이용한 하천 교란 실태의 분석(I))

  • Park, Eun-Ji;Kim, Kye-Hyun;Lee, On-Kil
    • Journal of Korea Spatial Information System Society
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    • v.10 no.2
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    • pp.81-93
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    • 2008
  • Current re-arrangement of river and waterway has been made uniformly ignoring characteristics of individual rivers thereby aggravating artificial river restructuring. Subsequently this severely affects the rivers' physical, chemical, and biological phenomenon. On the contrary, quantitative techniques to evaluate the aftermath of artificial river disturbance such as uprising of river bed, intrusion of foreign fisheries, and changes of ecological habitats are not available. To establish such quantitative techniques, analysis of river changes to evaluate the major causes of the river disturbance and its impacts is essential. Therefore, this study mainly focused on proposing a method which can be applied for the development of techniques to investigate river disturbance according to the major factors for the domestic rivers using airphotos and GIS techniques. For the analysis, the study area on the downstream of the river was selected and airphotos of the area were converted into GIS format to generate 'shape' files to secure waterways, river banks, and auxiliary data required for analyzing river disturbance. Trend analysis of the waterway sinuosity and changes of the flow path leaded to detailed verification of the river disturbance for specific location or time period, and this enabled to relatively accurate numbers representing sinuosity of the waterway and relevant changes. As the major results from the analysis, the relocation of waterways and the level of river sinuosity were quantified and used to verify the impacts on the stability of the waterways especially in the downstream of the dam. The results from this study enabled effective establishing proper measures against waterways' unstability, and emphasized subsequent researches for identifying better alternatives against river disturbances.

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A design of fuzzy pattern matching classifier using genetic algorithms and its applications (유전 알고리즘을 이용한 퍼지 패턴 매칭 분류기의 설계와 응용)

  • Jung, Soon-Won;Park, Gwi-Tae
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.33B no.1
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    • pp.87-95
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    • 1996
  • A new design scheme for the fuzzy pattern matching classifier (FPMC) is proposed. in conventional design of FPMC, there are no exact information about the membership function of which shape and number critically affect the performance of classifier. So far, a trial and error or heuristic method is used to find membership functions for the input patterns. But each of them have limits in its application to the various types of pattern recognition problem. In this paper, a new method to find the appropriate shape and number of membership functions for the input patterns which minimize classification error is proposed using genetic algorithms(GAs). Genetic algorithms belong to a class of stochastic algorithms based on biological models of evolution. They have been applied to many function optimization problems and shown to find optimal or near optimal solutions. In this paper, GAs are used to find the appropriate shape and number of membership functions based on fitness function which is inversely proportional to classification error. The strings in GAs determine the membership functions and recognition results using these membership functions affect reproduction of next generation in GAs. The proposed design scheme is applied to the several patterns such as tire tread patterns and handwritten alphabetic characters. Experimental results show the usefulness of the proposed scheme.

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A DNA Index Structure using Frequency and Position Information of Genetic Alphabet (염기문자의 빈도와 위치정보를 이용한 DNA 인덱스구조)

  • Kim Woo-Cheol;Park Sang-Hyun;Won Jung-Im;Kim Sang-Wook;Yoon Jee-Hee
    • Journal of KIISE:Databases
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    • v.32 no.3
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    • pp.263-275
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    • 2005
  • In a large DNA database, indexing techniques are widely used for rapid approximate sequence searching. However, most indexing techniques require a space larger than original databases, and also suffer from difficulties in seamless integration with DBMS. In this paper, we suggest a space-efficient and disk-based indexing and query processing algorithm for approximate DNA sequence searching, specially exact match queries, wildcard match queries, and k-mismatch queries. Our indexing method places a sliding window at every possible location of a DNA sequence and extracts its signature by considering the occurrence frequency of each nucleotide. It then stores a set of signatures using a multi-dimensional index, such as R*-tree. Especially, by assigning a weight to each position of a window, it prevents signatures from being concentrated around a few spots in index space. Our query processing algorithm converts a query sequence into a multi-dimensional rectangle and searches the index for the signatures overlapped with the rectangle. The experiments with real biological data sets revealed that the proposed method is at least three times, twice, and several orders of magnitude faster than the suffix-tree-based method in exact match, wildcard match, and k- mismatch, respectively.

Optical Multi-Normal Vector Based Iridescence BRDF Compression Method (광학적 다중 법선 벡터 기반 훈색(暈色)현상 BRDF 압축 기법)

  • Ryu, Sae-Woon;Lee, Sang-Hwa;Park, Jong-Il
    • Journal of KIISE:Computer Systems and Theory
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    • v.37 no.3
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    • pp.184-193
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    • 2010
  • This paper proposes a biological iridescence BRDF(Bidirectional Reflectance Distribution Function) compression and rendering method. In the graphics technology, iridescence sometimes is named structure colors. The main features of these symptoms are shown transform of color and brightness by varying viewpoint. Graphics technology to render this is the BRDF technology. The BRDF methods enable realistic representation of varying view direction, but it requires a lot of computing power because of large data. In this paper, we obtain reflection map from iridescence BRDF, analyze color of reflection map and propose representation method by several colorfully concentric circle. The one concentric circle represents beam width of reflection ray by one normal vector. In this paper, we synthesize rough concentric by using several virtually optical normal vectors. And we obtain spectrum information from concentric circles passing through the center point. The proposed method enables IBR(image based rendering) technique which results is realistic illuminance and spectrum distribution by one texture from reduced BRDF data within spectrum.

Vegetation Water Status Monitoring around China and Mongolia Desert using Satellite Data (위성자료를 이용한 중국과 몽골 사막주변의 식생수분상태 모니터링)

  • Lee, Ga-Lam;Kim, Young-Seup;Han, Kyoung-Soo;Lee, Chang-Suk;Yeom, Jong-Min
    • Journal of the Korean Association of Geographic Information Studies
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    • v.11 no.4
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    • pp.94-100
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    • 2008
  • Recently, global warming for climate system is a crucial issue over the world and it brings about severe climate change, abnormal temperature, a downpour, a drought, and so on. Especially, a drought over the earth surface accelerates desertification which has been advanced over the several years mainly originated from a climatic change. The objective of this study is to detect variation of vegetation water condition around China and Mongolia desert by using satellite data having advantage in observing surface biological system. In this study, we use SPOT/VEGETATION satellite image to calculate NDWI (Normalized Difference Water Index) around study area desert for monitoring of status of vegetation characteristics. The vegetation water status index from remotely sensing data is related to desertification since dry vegetation is apt to desertify. We can infer vegetation water status using NDWI acquired by NIR (Near infrared) and SWIR (Short wave infrared) bands from SPOT/VGT. The consequence is that NDWI decreased around desert from 1999 to 2006. The areas that NDWI was decreased are located in the northeast of Mongolian Gobi desert and the southeast of China Taklamakan desert.

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Evolution of Agrometeorology at the Global Level (농업기상학의 역사)

  • Sivakumar, M.V.K.
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.6 no.2
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    • pp.127-139
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    • 2004
  • Agricultural meteorology has advanced during the last 100 years from a descriptive to a quantitative science using physical and biological principles. The agricultural community is becoming more aware that using climate and weather information will improve their profitability and this will no doubt increase the demand for agrometeorological services. Hence it is timely that the needs and perspectives for agrometeorology in the 21$^{21}$ Century are grouped under two major headings: agrometeorological services for agricultural production and agrometeorological support systems for such services. Emphasis must be placed on the components of such support systems comprising of data, research, policies and training/education/extension. As Monteith (2000) mentioned, food supplies ultimately depend upon the skill with which farmers ran exploit the potential of good weather and minimize the impact of bad weather. Recent developments in instrumentation, data management systems, climate prediction, crop modelling, dissemination of agrometeorological information etc., provide agrometeorologists the tools necessary help the farmers improve such skills. The future for operational applications of agricultural meteorology appears bright and such applications could contribute substantially to promote sustainable agriculture and alleviate poverty.