• 제목/요약/키워드: Biological evaluation

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Fenton 산화법에 의한 매립장 침출수의 생물 분해성 증진에 관한 평가 (Evaluation on Enhanced Biodegradability in Landfill Leachate by Fenton Oxidation)

  • 이병대
    • 한국응용과학기술학회지
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    • 제22권3호
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    • pp.250-256
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    • 2005
  • This study was aimed to investigate treatment feasibility of leachate from D landfill that is located in gyr대ungbuk. From the analytical results of leachate, organic and nonbiodegradable matters were contained in high concentration. Thus chemical treatment was introduced to degrade nonbiodegradable matters in pre or post biological process. Two types of Fenton oxidation were adapted in this study. The first one is pre treatment process before biological treatment. The second one is post treatment process after biological treatment. The optimal conditions of both treatment methods were investigated as follows. In case of pre treatment process, the optimal conditions appeared in $Fe^{+2}/H_2O_2$(mmol/mmol): 0.1, $H_2O_2/CODcr$(mg/mg): 27.0, pH: 3 and reaction time: 2hrs. On the other hand, in case of post treatment process, the optimal conditions appeared in $Fe^{2+}$(mmol/mmol): 0.14, $H_2O_2/COD_{cr}$(mg/mg): 57.4, pH: 3 and reaction time: 1.25hrs. In the above optimal conditions, high COD removal was obtained in pre and post treatment process. Also it can expect that Fenton oxidation converted nonbiodegradable matters into biodegradable matters.

Evaluation of interfacial tension for poly(methyl methacrylate) and polystyrene by rheological measurements and interaction parameter of the two polymers

  • Sung, Y.T.;Seo, W.J.;Kim, Y.H.;Lee, H.S.;Kim, W.N.
    • Korea-Australia Rheology Journal
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    • 제16권3호
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    • pp.135-140
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    • 2004
  • Morphological and rheological properties of the poly(methyl methacrylate) (PMMA) and polystyrene (PS) blends were studied by scanning electron microscopy (SEM) and advanced rheometric expansion system (ARES). From the SEM results, the PMMA-PS blends showed dispersed morphology and the particle size of the dispersed phase was quite small (0.1~0.6 $\mu\textrm{m}$ compared with other immiscible polymer blends. Values of the interfacial tension of the PMMA-PS blend were obtained from the Choi-Schowalter and the Palierne emulsion models using the storage modulus of the PMMA and PS, and found to be 1.0 and 2.0 mN/m, respectively. The interfacial tension between the PMMA and PS was also calculated from the Flory-Huggins polymer-polymer interaction parameter ($\chi$) and found to be from 0.98 to 1.86 mN/m depending on the molecular weight and composition. Comparing the values of the interfacial tension from the Flory-Huggins polymer-polymer interaction parameter and the values measured by oscillatory rheometer, it is suggested that the interfacial tension of the PMMA-PS blend obtained from the polymer-polymer interaction parameter are in good agreement with the values obtained by rheological measurements.

Evaluation of Anti-inflammatory Activities and Mechanisms of Microalga Phaeodactylum tricornutum

  • Kim, Jeong Hwa;Kim, Sang Min;Pan, Cheol-Ho;Choi, Joong-Kook;Lee, Jae Kwon
    • Journal of Applied Biological Chemistry
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    • 제56권2호
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    • pp.61-67
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    • 2013
  • Due to their diversity and abundancy, marine resources have emerged as important biological resources to compensate the limited sources of terrestrial biological materials. Phaeodactylum tricornutum (PT) is one of classical model diatoms most widely studied for its ecology, physiology, biochemistry and molecular biology. In this study, four different PT extracts on lipopolysaccharide (LPS)-stimulated macrophages were compared for anti-inflammatory effect and investigated for the underlying mechanisms. The extracts of PT inhibited nitric oxide production from LPS stimulated RAW 264.7 cells in a dose dependent manner. These extracts also inhibited the expression of mRNA and production of proteins of pro-inflammatory cytokines such as interleukin (IL)-$1{\beta}$, IL-6 and tumor necrosis factor-${\alpha}$. These inhibitory effects were found to be caused by blockage of nuclear factor-${\kappa}B$ activation and phosphorylation of p38 mitogen-activated protein kinases, extracellular signal-regulated kinases 1 and 2 and c-Jun N-terminal kinase.

전문간호사 과정의 기초간호과학 교과목 교육에 대한 실태조사 - 병태생리학, 약리학을 중심으로 - (Survey on the Students' Evaluation and the Administrational Status of Biological Nursing Science Subjects in Advanced Practice Nursing Programs)

  • 이여진;조경숙
    • Journal of Korean Biological Nursing Science
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    • 제13권3호
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    • pp.193-203
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    • 2011
  • Purpose: The purpose of this study was to investigate and compare the level of importance, difficulty, satisfaction, and needs of biological nursing science courses-pathophysiology and pharmacology- among students of Advanced Practice Nursing Programs. Methods: A cross-sectional descriptive study using a self-report questionnaire has been adopted. Participants in this survey were 436 graduate students enrolled in an Advanced Practice Nursing Program. Using SPSS WIN 18.0 program, descriptive statistics, chi-square test, and t-test were conducted. Results: In a pathophysiology course, the students taught by nurse lecturers presented a higher level of importance and satisfaction than those were taught by non-nurse lecturers, but the difference was not significant statistically. In a pharmacology course, the students were taught by nurse lecturers expressed a higher level of satisfaction than those were taught by non-nurse lecturers, but the difference was not significant statistically. The students wanted to improve the quality of courses. Conclusion: According to the findings of this study, we should try to improve the quality of classes and to increase the number of courses taught by nurse-lecturers.

Biofiltration of Air Streams Contaminated Hydrogen Sulfide : Performance Evaluation of Different Carriers

  • Jeong, Gwi-Taek;Lee, Gwang-Yeon;Lee, Kyoung-Min;Cha, Jin-Myoung;Joe, Yong-Il;Park, Don-Hee
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2005년도 생물공학의 동향(XVII)
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    • pp.456-462
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    • 2005
  • The objective of this study was to develop a removal process by which $H_2S$ could be biologically removed from the odoriferous gases generated in the waste food recycling process. In order to develop this process we were first required to select a proper biofilter support protocol. When the selected biofilter equipment was then tested suing a synthetic odoriferous gas containing 600 ppm of $H_2S$, we noted a maximal removal rate of 658 $g-H_2S/m^3{\cdot}hr$, using polypropylene fibrils as supporting materials. Under identical experimental conditions, we obtained a value of 411.2 $g-H_2S/m^3{\cdot}hr$, using polyurethane as a support material. We also conducted a trial in which volcanic stone was utilized as a support material, and in this trial, we logged a maximal 105.1 $g-H_2S/m^3{\cdot}hr$ removal rate. As the result of our experiments, we concluded that polypropylene fibrils constituted the ideal material for the removal of $H_2S$ gas via biological treatment.

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Effect of Temperature Change on the Respiration Characteristics of Vegetables

  • Kawagoe, Yoshinori;Seo, Yasuhisa;Oshita, Sei-Ichi;Sagara, Yasuyuki
    • 한국농업기계학회:학술대회논문집
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    • 한국농업기계학회 1996년도 International Conference on Agricultural Machinery Engineering Proceedings
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    • pp.947-952
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    • 1996
  • The effect of fluctuating temperature on the respiration of vegetables has been investigated. Spinach was selected as the experimental material because of its high respiratory activity and kept under the condition that temperature changed alternately at low and high levels every 4 hours. The low-high level temperature combination was set in $1-10^{\circ}C,{\;}1-20^{\circ}C{\;}and{\;}1-30^{\circ}C$. Respiration was evaluated in terms of quantity of $CO_2$ evolved from spinach. The evolution rate of $CO_2$ was determined by a change in its concentration. The evaluation rate of $CO_2$ followed closely the temperature change. In the temperature combinations at $1-10^{\circ}C{\;}and{\;}1-20^{\circ}C$, the relationship between $CO_2$ evolution rate and temperature was found to be able to express by Arrhenius law, while at $1-30^{\circ}C$, it did not obey the law.

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생태 건강성 평가로서 분자지표에서 군집지표 수준까지의 다양한 변수분석 (Analysis of Various Ecological Parameters from Molecular to Community Levels for Ecological Health Assessments)

  • 이채훈;안광국
    • 생태와환경
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    • 제43권1호
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    • pp.24-34
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    • 2010
  • This study was carried out to analyze some influences on ecological health conditions, threaten by various stressors such as physical, chemical and biological parameters. We collected samples in 2008 from three zones of upstream, midstream and downstream, Gap Stream. We applied multi-metric fish assessment index (MFAI), based on biotic integrity model to the three zones along with habitat evaluations based on Qualitative Habitat Evaluation Index (QHEI). We also examined fish fauna and compositions, and analyzed relations with MFAI values, QHEI values, and various guild types. Chemical parameters such as oragnic matter (BOD, COD), nutrients (TP, $NH_3$-N), coli-form number (as MPN), and suspended solids (SS) were analyzed to identify the relationship among multiple stressor effects. Using the sentinel species of Zacco platypus, the population structures and condition factors were analyzed along with DNA damages related with genotoxicant effects by comet assay. This study using all these parameters showed that stream condition was degraded along the longitudinal gradient from upstream to downstream, and the downstream, especially, was impacted by nutrient enrichment and toxicant exposure from the point source, wastewater treatment plant. Overall results indicated that our approaches applying various parameters may be used as a cause-effect technique in the stream health assessments and also used as a pre-warning tool for diagnosis of ecological degradation.

콜라겐과 무세포진피를 이용한 혼합형 인공피부 개발 및 쥐 모델에서 창상치료 적용 (Application of a Composite Skin Equivalent using Collagen and Acellular Dermal Matrix as the Scaffold in a Mouse Model of Full-thickness Wound)

  • 이동혁;윤진철;이정희;김인섭
    • KSBB Journal
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    • 제29권1호
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    • pp.42-49
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    • 2014
  • The aim of this study was to develop a composite human skin equivalent for wound healing. Collagen type1 and acellular dermal matrix powder were utilized as the scaffold with dermal fibroblasts and keratinocytes for the development of a composite human skin equivalent. Fibroblast maintained the volume of composite skin equivalent and also induced keratinocytes to attach and proliferate on the surface of composite skin equivalent. The composite human skin equivalent had a structure and curvature similar to those of real skin. Balb-C nu/nu mice were used for the evaluation of full-thickness wound healing effect of the composite human skin equivalent. Graft of composite skin equivalent on full-thickness wound promoted re-epithelialization and granulation tissue formation at 9 days. Given the average wound-healing time (14 days), the wound in the developed composite skin equivalent healed quickly. The overall results indicated that this three-dimensional composite human skin equivalent can be used to effectively enhance wound healing.

Evaluation of Benthic Macroinvertebrate Diversity in a Stream of Abandoned Mine Land Based on Environmental DNA (eDNA) Approach

  • Bae, Mi-Jung;Ham, Seong-Nam;Lee, Young-Kyung;Kim, Eui-Jin
    • 생태와환경
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    • 제54권3호
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    • pp.221-228
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    • 2021
  • Recently, environmental DNA (eDNA)-based metabarcoding approaches have been proposed to evaluate the status of freshwater ecosystems owing to various advantages, including fast and easy sampling and minimal habitat disruption from sampling. Therefore, as a case study, we applied eDNA metabarcoding techniques to evaluate the effects of an abandoned mine land located near a headwater stream of Nakdonggang River, South Korea, by examining benthic macroinvertebrate diversity and compared the results with those obtained using the traditional Surber-net sampling method. The number of genera was higher in Surber-net sampling (29) than in the eDNA analysis (20). The genus richness tended to decrease from headwater to downstream in eDNA analysis, whereas richness tended to decrease at sites with acid-sulfated sediment areas using Surber-net sampling. Through cluster analysis and non-metric multidimensional scaling, the sampling sites were differentiated into two parts: acid-sulfated and other sites using Surber-net sampling, whereas they were grouped into the two lowest downstream and other sites using eDNA sampling. To evaluate freshwater ecosystems using eDNA analysis in practical applications, it is necessary to constantly upgrade the methodologies and compare the data with field survey methods.

외상 후 정신 장애의 장해 평가에 대한 정신과 전문가의 일반 의견 (Opinion of Experts about Psychiatric Evaluation after Trauma in Korea)

  • 이병철;류성곤;정한용
    • 생물정신의학
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    • 제15권4호
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    • pp.310-315
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    • 2008
  • Objectives : The evaluation of disability after trauma in psychiatry is relatively subjective compared with other departments. A consensus among evaluators could improve reliability of evaluations. We compared disability rate of common psychiatric disorders without definite brain injury depending on their diagnosis from experienced evaluators in Korea. Methods : A written questionnaire was mailed to each evaluator and the reply was analyzed. The questions included disability rate ranges of postconcussional syndrome, PTSD and depression. Other questions related with admission for evaluation, expected duration of treatment, life expectancy and need of supporting person were also asked. Results : Range of disability rate were from $8.6{\pm}4.5%$ to $26.6{\pm}12.8%$ in postconcussional syndrome, from $10.4{\pm}6.8%$ to $36.4{\pm}13.8%$ in PTSD and from $10.0{\pm}4.6%$ to $30.6{\pm}10.3%$ in depressive disorder. There were lots of diversity in expected duration of treatment with psychiatric disability. Decline of life expectancy and need of supporting person were considered at least 50% of disability. Conclusion : There is much diversity in evaluation of psychiatric disabilities with disability rate and expected duration of treatments even among experienced evaluators. A common consensus among experts may increase reliability of psychiatric evaluations after trauma.

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