• JSTS:Journal of Semiconductor Technology and Science
• /
• v.17 no.2
• /
• pp.294-301
• /
• 2017

This paper presents a low power ${\Sigma}{\Delta}$ modulator for an implantable chip to acquire a bio-signal such as EEG, DBS, and EMG. In order to reduce a power consumption of the proposed fourth order modulator, two op-amps utilized for the first two integrators are reconfigured to drive the second two integrators. The KT/C noise reduction circuit in the first two integrators is employed to enhance SNR of the modulator. The proposed circuit was fabricated in a 0.18 um CMOS n-well 1 poly 6 metal process with the active chip core area of $900um{\times}800um$ and the power consumption of 830 uW. Measurement results were demonstrated to be SNDR of 76 dB, DR of 77 dB, ENOB of 12.3 bit at the input frequency of 250 Hz and the clock frequency of 256 kHz. FOM1 and FOM2 were measured to be 41 pJ/step and 142.4 dB, respectively.

• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.05
• /
• pp.263-266
• /
• 1997

The purpose of this paper is the development of Integrated Bio-signal Management System. (IBMS) using the network. IBMS is the system to manage the medical signals that measured from the each independent medical measurement system module. Each has a LAN Card. We developed the Network Application using Socket Library. Also, we developed the Graphic User Interface software for IBMS using Visual C++ on Windows 95.

• Journal of Korea Multimedia Society
• /
• v.18 no.5
• /
• pp.652-662
• /
• 2015

It is necessary to develop small, implantable bio-telemetry systems which can measure and transmit patients' bio-signals from internal body to external receiver. When measuring bio-signals, like electrical bio-signals, acoustic bio-signal measurement has also a big clinical usefulness. But, sound signal has larger frequency bandwidth than any other bio-signals. When considering these issues, a wireless telemetry system which has rapid data transmission rate proportional to wide frequency bandwidth is necessary to be developed. The bluetooth module is used to overcome the data rate limitation caused by the large frequency bandwidth. In this paper, a novel multimedia bluetooth biotelemetry system was developed which consists of transmitter module located in the body and receiver device located outside of the body. The transmitter consists of microphone, bluetooth, and wireless charging device. And the receiver consists of bluetooth and codec system. The sound inside the skin is captured by microphone and sent to receiver by bluetooth while charging. The wireless charging system constantly supplies the electric power to the system. To verify the performance of the developed system, an in vitro experiment has been performed. The results show that the proposed biotelemetry system has ability to acquire the sound signals under the skin.

• Journal of Magnetics
• /
• v.11 no.4
• /
• pp.189-194
• /
• 2006

The recent development of bio-conjugated magnetic nanoparticles offers many opportunities for applications in the field of biomedicine. In particular, the use of magnetic nanoparticles for biosensing has generated widespread research efforts following the progress of various magnetic field sensors. Here we demonstrate substrate-free biosensing approaches based on the Brownian rotation of ferromagnetic nanoparticles suspended in liquids. The signal transduction is through the measurement of the magnetic ac susceptibility as a function of frequency, whose peak position changes due to the modification of the hydrodynamic radius of bio-conjugated magnetic nanoparticles upon binding to target bio-molecules. The advantage of this approach includes its relative simplicity and integrity compared to methods that use substrate-based stray-field detectors.

• Korean Journal of Optics and Photonics
• /
• v.20 no.3
• /
• pp.182-188
• /
• 2009

The surface plasmon resonance ellipsometer (SPRE), using a multiple air injection system with an extraction of air system, has been proposed and developed to minimize measurement error of signals due to diffusion of reagent into running buffer. Since the diffusion of reagent into running buffer affects the refractive index of the running buffer by changing the concentration, characteristics of binding between various bio-molecules don't appear clearly in measurement results. The diffusion between running buffer and reagent can be blocked by using an air bubble injection system. An extraction of air system is used to remove the noise signal due to unnecessary air bubbles flowing in a channel. Reliability of measurement results has been improved by using the valve system.

• Proceedings of the IEEK Conference
• /
• 2009.05a
• /
• pp.357-359
• /
• 2009

In this paper, the 2.4GHz doppler radar system consisting of the doppler radar module and a baseband module were designed to detect heartbeat and respiration signal without direct skin contact. A bio-radar system emits continuous RF signal of 2.4GHz toward human chest, and then detects the reflected signal so as to investigate cardiopulmonary activities. The heartbeat and respiration signals acquired from quadrature signal of the doppler radar system are applied to the pre-processing circuit, amplification circuit, and the offset circuit of the baseband module. ECG(electrocardiogram) and reference respiration signals are measured simultaneously to evaluate the doppler radar system. As a result, the respiration signal of doppler radar signal is detected to 1m without complex digital signal processing. The sensitivity and calculated from I/Q respiration signal were $98.29{\pm}1.79%$, $97.11{\pm}2.75%$, respectively, and positive predictivity were $98.11{\pm}1.45%$, $92.21{\pm}10.92%$, respectively. The sensitivity and positive predictivity calculated from phase and magnitude of the doppler radar were $95.17{\pm}5.33%$, $94.99{\pm}5.43%$, respectively. In this paper, we confirmed that noncontact real-time heartbeat and respiration detection using the doppler radar system has the possibility and limitation.

• Proceedings of the KSME Conference
• /
• 2004.11a
• /
• pp.1540-1545
• /
• 2004

Measurement of concentration fields in a micro-channel is the crucial technology in the area of Lab-on-a-chip to be used for various bio-chemical applications. It is wel-known that the only possible way to measure the concentration field in the micro-channel is using micro-LIF(Laser Induced Fluorescence) method. However, an accurate concentration field at a given cross plane in a micro-channel has not been made so far due to the limit of light illumination. The present study demonstrates a novel method to provide an ultra thin laser sheet beam having 5 microns thickness by a micro focus laser line generator. Nile Blue A was used as fluorescent dye for LIF measurement. The laser sheet beam illuminates an exact plane of concentration measurement in the micro-channel to increase the signal to noise ratio and reduce the depth uncertainty considerably.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2022.05a
• /
• pp.41-43
• /
• 2022

In order to prevent and block infectious diseases caused by the recent COVID-19 pandemic, non-contact biometric information acquisition and analysis technology is attracting attention. The invasive and attached biometric information acquisition method accurately has the advantage of measuring biometric information, but has a risk of increasing contagious diseases due to the close contact. To solve these problems, the non-contact method of extracting biometric information such as human fingerprints, faces, iris, veins, voice, and signatures with automated devices is increasing in various industries as data processing speed increases and recognition accuracy increases. However, although the accuracy of the non-contact biometric data acquisition technology is improved, the non-contact method is greatly influenced by the surrounding environment of the object to be measured, which is resulting in distortion of measurement information and poor accuracy. In this paper, we propose a context-based bio-signal modeling technique for the interpretation of personalized information (image, signal, etc.) for bio-information analysis. Context-based biometric information modeling techniques present a model that considers contextual and user information in biometric information measurement in order to improve performance. The proposed model analyzes signal information based on the feature probability distribution through context-based signal analysis that can maximize the predicted value probability.

• Progress in Medical Physics
• /
• v.5 no.2
• /
• pp.35-43
• /
• 1994

Electromagnetic wave may induce effect and damage on the bio-body, either by electric fields of magnetic fields. We measure electrophysiological changs in rabbit's brain exposed to 2.45GHz micro wave(power density 40mW/cm$^2$) which distance 30cm from the source. In order to process the bio-electrical signal (EEG), used pre-amplifier module with self-made and Digtal analyzer computer system. Spectal analysis of the EEG showed variable power in the frequency range(1～30Hz) through each exposure time(10min, 20min, 30min) before and after. In effectively measured by the bio-electrical signal processing and can found threshold of minmal permissible exposure and lethal exposure.

• Journal of Radiation Protection and Research
• /
• v.32 no.1
• /
• pp.27-34
• /
• 2007

In this paper, We are evaluated about bio-signal between general workers and nuclear medicine workers which is more radiation exposure relatively. In order to reciprocal evaluated two group, we experimented nuclear medicine workers in Chung-Buk National University Hospital at department of nuclear medicine and worker in Chon-Nam National University Hospital at CT room, general radiographic room, medical recording room, receipt room, general office room. Used of experimental Equipments as follows, for a level of radiation measurement by pocket dosimeter which made by Arrow-Tech company, for heart rate and blood pressure measurement by TONOPORT V which made by GE medical systems company, for heat flux and skin temperature and energy expenditure measurement by Armband senseware 2000 which made by Bodymedia company. Result of experiment obtains as follows: 1) Individual radiation exposure is recorded 3.05 uSv at department of nuclear medicine and order as follows CT room, general radiograpic room, medical recording room, receipt room, general office room. Department of nuclear medicine more 1.5 times than other places. 2) Radiation accumulated dose is not related to Heat flux, Skin temperature, Energy expenditure. 3) Blood pressure is recorded equal to nuclear medical workers, general officer, general people about systolic blood pressure and diastolic blood pressure. Compared to blood pressure between nuclear medical works which is more radiation exposure and other workers was not changed. Consequently, more radiation exposed workers at nuclear medicine field doesn't have hazard.