• 한국산업융합학회 논문집
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• 제22권3호
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• pp.373-379
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• 2019

Nowadays, the IoT portable electronic devices have become more useful and diverse, so they require various supply voltage levels to operate. This paper presents a DC-DC buck converter with pulse width modulation (PWM) for portable electronic devices. The proposed step-down DC-DC converter consists of passive elements such as capacitors, inductors, and resistors and an integrated chip (IC) for signal control to reduce power consumption and improves ripple voltage with the resolution. The proposed DC-DC converter is simulated and analyzed in PSPICE circuit design platform, and implemented on the prototype PCB board with a Texas Instruments LM5165 IC. The proposed buck converter is showed 92.6% of peak efficiency including a load current range of 4-10 mA, 3.29 mV of the voltage ripple at 5 V output voltage for the supply voltage 12 V. Measured and Simulated power efficiency are made good agreement with each other.

• 대한임상검사과학회지
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• 제47권1호
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• pp.39-45
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• 2015

We investigated whether multiple infections can be used as predictors of progression to carcinogenesis in accordance with the cytological diagnosis in women receiving abnormal cytologic diagnosis as analysis genotype and compared to single infection. HPV prevalence is highest in the age of under 30 years old woman, HPV prevalence is started to lower after 30 years old and started to increase over 60 years old as like a U-shape. The specific HPV genotypes is an important factor because increased single infection and reduced multiple infections and appeared single infection with AC in progressing carcinogenesis. HPV 16 revealed the statistical significance at the single infection in squamous cell lesions, and HPV 18 revealed the statistical significance at the single infection in adenocarcinoma with showed HPV 16, 58, 18, 52-type distribution.

• 식품과학과 산업
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• 제54권3호
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• pp.145-159
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• 2021

Conventional nutrition services involve producer-oriented approaches without considering the differences in the characteristics and circumstances of each individual, whereas personalized nutrition services are consumer-oriented concepts that provide products and services for maintaining optimal health conditions based on the genetic, physiological, and metabolic characteristics of individuals, with these products based on balanced nutrition and healthy living. Currently, methods for evaluating dietary habits, monitoring dietary behaviors, deep phenotyping, and metabotyping via microbiota profiling, as well as methods for predicting big data by using machine learning, have been previously studied in Korea and abroad. With the development of medical technology and the improvement of hygiene, the demand for personalized nutrition and health services for healthier, happier, and more satisfying lives is rapidly increasing. Therefore, based on scientific technologies, attempts are needed to advance these services into global personalized markets and to boost the global competitiveness of countries and companies.

• 한국엔터테인먼트산업학회논문지
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• 제15권3호
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• pp.193-202
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• 2021

본 연구는 4차 산업혁명에 대한 보건계열 학생들의 인식과 교육 요구도를 조사하고, 보건의료 인력을 양성하기 위한 방향설정과 교육방안을 마련하고자 실시하였다. 이에 G도시에 소재한 H대학에 재학중인 보건계열 전공대학생 280명을 대상으로 성별, 학년에 따른 인식과 교육요구도를 비교 분석하였다. 여학생들은 4차 산업혁명에 대해 긍정적으로 인식하였으며, 학년이 낮을수록 전공영역에 미치는 영향에 대해 높은 인식을 나타내었다. 4차 산업혁명에 의한 영향에 대해서는 남학생의 경우 세대차이 심화(p<0.05), 빈부의 격차 심화(p<0.01), 개인정보침해 심화(p<0.05), 기존 일자리의 감소(p<0.05), 인공지능의 남용(p<0.05)과 같은 부정적인 요인에서 높은 것으로 나타났다. 보건계열 학생들은 4차 산업혁명에 대비해 바이오와 의료기기에 관한 교육(22.2%)을 가장 많이 희망하고 있었다. 4차 산업혁명의 영향에 대해 보건계열 학생들이 긍정적으로 인식할수록 교육 요구도가 높게 나타났다(p<0.001). 따라서 보건계열 학생들이 4차 산업혁명시대에 새로운 일자리의 창출과 삶의 질 향상과 같은 긍정적 요인이 향상될 수 있도록 프로그램 개발과 다양한 교육의 실시가 필요하다고 사료된다.

• 센서학회지
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• 제28권5호
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• pp.299-304
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• 2019

Recently, the development of rehabilitation medical technology has resulted in an increased interest in speech therapy equipment. In particular, research on articulation therapy for communication disorders is being actively conducted. Existing methods for the diagnosis and treatment of speech disorders have many limitations, such as traditional tactile perception tests and methods based on empirical judgment of speech therapists. Moreover, the position and tension of the tongue are key factors of speech disorders with regards to articulation. This is a very important factor in the distinction of Korean characters such as lax, fortis, and aspirated consonants. In this study, we proposed a Korean electropalatography (EPG) system to easily measure and monitor the position and tension of the tongue in articulation treatment and diagnosis. In the proposed EPG system, a sensor was fabricated using an AgCl electrode and biocompatible silicon. Furthermore, the measured signal was analyzed by implementing the bio-signal processing module and monitoring program. In particular, the bio-signal was measured by inserting it into the palatal from an experimental control group. As a result, it was confirmed that it could be applied to clinical treatment in speech therapy.

• Fisheries and Aquatic Sciences
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• 제26권6호
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• pp.406-422
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• 2023

Sarcopenia is an age-related, progressive skeletal muscle disorder involving the loss of muscle mass and strength. Previous studies have shown that γ-aminobutyric acid (GABA) from fermented oysters aids in regulatory T cells (Tregs) cell expansion and function by enhancing autophagy, and concomitantly mediate muscle regeneration by modulating muscle inflammation and satellite cell function. The fermentation process of oysters not only increases the GABA content but also enhances the content of branched amino acids and free amino acids that aid the level of protein absorption and muscle strength, mass, and repair. In this study, the effect of GABA-enriched fermented sarco oyster extract (FSO) on reduced muscle mass and functions via Treg modulation and enhanced autophagy in aged mice was investigated. Results showed that FSO enhanced the expression of autophagy markers (autophagy-related gene 5 [ATG5] and GABA receptor-associated protein [GABARAP]), forkhead box protein 3 (FoxP3) expression, and levels of anti-inflammatory cytokines (interleukin [IL]-10 and transforming growth factor [TGF]-β) secreted by Tregs while reducing pro-inflammatory cytokine levels (IL-17A and interferon [IFN]-γ). Furthermore, FSO increased the expression of IL-33 and its receptor IL-1 receptor-like 1 (ST2); well-known signaling pathways that increase amphiregulin (Areg) secretion and expression of myogenesis markers (myogenic factor 5, myoblast determination protein 1, and myogenin). Muscle mass and function were also enhanced via FSO. Overall, the current study suggests that FSO increased autophagy, which enhanced Treg accumulation and function, decreased muscle inflammation, and increased satellite cell function for muscle regeneration and therefore could decrease the loss of muscle mass and function with aging.

• 한국식품저장유통학회지
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• 제18권6호
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• pp.817-823
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• 2011

Angelicae gigas Nakai has been used as a traditional medicine as well as an edible vegetable in South Korea. In this study, the total phenolic and flavonoid content and antioxidants of A. gigas Nakai leaves were examined in vitro via hydroxyl-radical-scavenging activity, reducing power activity, metal chelating assay, and DPPH-free -radical-scavenging assay. Among all the extracts from A. gigas Nakai leaves, the ethanol extract showed the strongest effects in all of the assays. The $EC_{50}$ values for the DPPH-radical-scavenging activities of ethanol, methanol, and water extracts were 31.47, 42.14, and $58.47{\mu}g/mL$, respectively. Among the extracts from A. gigas Kakai leaves, the ethanol extract had the highest levels of total phenolics ($7.84{\pm}1.46$ mg TAN/g) and total flavonoids ($4.23{\pm}0.03$ mg QE/g), which correlated strongly with the individual phenolic-compound (p-hydroxybenzoic acid, vanillin, and trans-ferulic acid) contents. The ethanol extract also showed stronger antioxidant activity than tocopherol in hydroxyl- radical-scavenging activity assay. These results indicate that the ethanol extract of A. gigas Kakai leaves possesses significant antioxidant properties, which suggests its great potential as a functional-food ingredient in the food industry.

• 한국미생물·생명공학회지
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• 제45권1호
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• pp.1-11
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• 2017

본 논문에서는 나노셀룰로오스의 일종으로 최근 가장 주목을 받고 있는 소재인 마이크로피브릴화 셀룰로오스에 대하여 살펴보았다. 마이크로피브릴화 셀룰로오스는 리그노셀룰로오스계 바이오매스의 셀룰로오스에서 유래한 섬유로 풍부하고, 재생가능하며, 지속 가능한 천연 소재의 일종이다. 주로 물리적 전처리에 의해 생성되며, 나노미터에서 마이크로미터에 이르는 다양한 소섬유들의 결합으로 이루어져 있다. 이로 인해 마이크로피브릴화 셀룰로오스는 높은 표면적과, 높은 aspect ratio, 그리고 특이적인 용해성을 가지게 되고, 이는 전통적인 목재 산업 뿐만 아니라, 최신식의 식품/바이오/화학/의료 산업에 이르는 다양한 영역에의 적용 가능성을 보여주는 주요한 원인이 된다. 한편 이러한 응용력에도 불구하고, 아직 마이크로피브릴화 셀룰로오스는 제조 시 필요한 높은 에너지량과 반응성 조절의 어려움 때문에 상업적으로 많은 주목을 받지 못하고 있다. 따라서, 마이크로피브릴화 셀룰로오스의 기질에 대한 특성을 이해 및 구체화하고, 마이크로피브릴화 셀룰로오스의 피브릴화도를 선택하며, 표면의 개량을 선택적으로 조절할 수 있는 시스템을 개발하는 연구가 필요할 것이다. 마이크로피브릴화 셀룰로오스가 향후 우리나라의 산업 전반에 걸쳐 활용될 수 있기를 기대해 본다.

• 시스템엔지니어링학술지
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• 제20권spc1호
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• pp.45-55
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• 2024

Amidst the challenges of the global economy, this paper examines the investment tendencies of professional angel investors, who provide venture capital and management consulting, and explores strategies to revitalize angel investment. According to the research findings, professional angel investors are generally older and more educated than regular angel investors, and they are concentrated in the metropolitan region. Additionally, their investment performance before and after registration remains similar, with investment amounts concentrated between 50 million and 100 million won. Their investment portfolios focus on ICT services, bio/medical, and distribution/service sectors. Based on these findings, policy and institutional support measures are required to revitalize angel investment, including easing registration requirements for professional angel investors, expanding tax benefits related to angel investment, strengthening the provision of information and education related to angel investment, and enhancing angel investment networking. This study is expected to contribute to the revitalization of the venture startup ecosystem and economic growth through the revitalization of angel investment.

• 대한의용생체공학회:의공학회지
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• 제37권5호
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• pp.195-207
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• 2016

This study examined the effectiveness of micro-current stimulation (MCS) to improve the facial skin qualities by performing clinical test. The MCS is generally known that provide healing response in the damaged tissue and pain relief through activating the adenosine triphosphate (ATP) and protein synthesis. In here, we can hypothesize that the improvement of facial skin qualities may occur due to MCS, since the induction of micro-current from outside may enhance the cellular activity according to ATP activation. From the clinical test, our results showed that a variety of evaluating categories, which is able to assess the skin qualities, significantly enhanced due to stimulation of micro-current after 7 and 14 days. Therefore, we can estimate that MCS in human facial skin may be effective to improve the skin qualities.