• Journal of Electrical Engineering and Technology
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• v.10 no.3
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• pp.1138-1143
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• 2015

Effects of fabrication process variations on impedance of microelectrodes integrated on a neural probe were examined through equivalent circuit modeling and SPICE simulation. Process variation and the corresponding range were estimated based on experimental data. The modeling results illustrate that the process variation induced by metal etching process was the dominant factor in impedance variation. We also demonstrate that the effect of process variation is frequency dependent. Another process variation that was examined in this work was the thickness variation induced by deposition process. The modeling results indicate that the effect of thickness variation on impedance is negligible. This work provides a means to predict the variations in impedance values of microelectrodes on neural probe due to different process variations.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.05a
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• pp.405-407
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• 2008

Body fat measures a large number places body because error is oversized that measure in single specification region to measure body whole body fat degree by non-invasive optical method and bio-electrical impedance method. Use LED source of light that center wavelength is 660nm wavelength and measure at same time by BIA(Bio-electrical Impedance Analysis) method And then photo-electricity method calculate fat correlation formula.

• Journal of Power System Engineering
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• v.13 no.1
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• pp.65-71
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• 2009

To address the need for new intelligent sensing, this paper introduces nano sensors made of carbon nanotube (CNT) composites and presents their preliminary experiments. Having smart material properties such as piezoresistivity, chemical and bio selectivity, the nano composite can be used as smart electrodes of the nano sensors. The nano composite sensor can detect structural deterioration, chemical contamination and bio signal by means of its impedance measurement (resistance and capacitance). For a structural application, the change of impedance shows specific patterns depending on the structural deterioration and this characteristic is available for an in-situ multi-functional sensor, which can simultaneously detect multi symptoms of the structure. This study is anticipated to develop a new nano sensor detecting multiple symptoms in structural, chemical and bio applications with simple electric circuits.

• Journal of Biomedical Engineering Research
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• v.32 no.3
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• pp.207-217
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• 2011

Electrode impedances are measured to quantitatively characterize the electrode-electrolyte or cell-electrode interfaces. In the case of high-density microelectrode arrays(MEAs) that have been developed for brainmachine interface applications, the characterization process becomes a repeating and time-consuming task; a system that can perform the measurement and analysis in an automated fashion with accuracy and speed is required. However, due to the large number of channels, parasitic capacitance and off-capacitance components of the switching system become the major factors that decreased the accuracy for the measurement of high impedance microelectrodes. Here we investigated the implementation of automatic impedance measurement system with analyzing the causes of possible measurement-related problems in multichannel switching configuration. Based on our multi-channel measurement circuit model, we suggest solutions to the problems and introduce a novel impedance measurement scheme using electro-mechanical relays. The implemented measurement system could measure |Z| < 700 $k{\Omega}$ of impedance in - 10% errors, which can be widely applicable to high density neural recording MEAs.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1977-1978
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• 2008

In this paper, we compare performance of common-mode rejection between a differential and a non-differential amplifier system with two electrodes. A differential amplifier system is constant for common-mode rejection ratio(CMRR) on the frequency domain. But a non-differential amplifier's CMRR is determined by $Z_{FB}/Z_e$ ($Z_{FB}$ ; feedback impedance, $Z_e$; electrode impedance). There is trade-off between a non-differential amplifier's CMRR and its differential input impedance. And a non-differential amplifier system has some advantages for a bio-potential measurement with two electrodes because a designer can control the impedance between the body and system's common.

• Journal of Korea Society of Industrial Information Systems
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• v.18 no.6
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• pp.9-16
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• 2013

Bio-impedance measurement system(BMS) is non-invasive and easy to implement a measurement method that allows determining the water content of a patient. The measurement conditions, the hardware specifications and the configurations of BMS devices must be well chosen in order to get correct and reproducible results. BMS was then conducted for the limbs and the thoracic using a lock-in amplifier and LabView control system with a frequency range of 1kHz-100kHz. From both the measurement data and the simulation results, we verified that the parameters in the proposed equivalent model and the trend of impedance variation according to the multi-frequency of applied current source are similar to those of human body. We believe that the real-time BMS developed in this study is highly reliable and applicable to the research on the clinical characteristics of the human being's impedance.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.12
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• pp.1671-1674
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• 2014

This paper presents a frequency-dependent cell impedance analysis chip for use in cancer and normal cell discrimination. The previous cell impedance analysis chips for flowing cells cannot allow enough time for cell-to-electrode contact to monitor frequency-dependent impedance response. Another type of the previous cell impedance analysis chips for the cells clamped by membranes need complex sample control for making stable cell-to-electrode contact. We present a new impedance analysis chip using the microchamber array, on which a PDMS cover is placed to make stable cell-to-electrode contact for the individual cell trapped in each microchamber; thus achieving frequency-dependent single-cell impedance analysis without complex sample control. Compared to the normal cells, the magnitude of NHBE cells is $60.07{\sim}97.41k{\Omega}$ higher than A549 cells in the frequency range of 95.6 kHz~2MHz and the phase of NHBE is $3.96^{\circ}{\sim}20.8^{\circ}$ higher than A549 cells in the frequency range of 4.37 kHz~2MHz, respectively. It is demonstrated experimentally that the impedance analysis chip performs frequency-dependent cell impedance analysis by making stable cell-to-electrode contact with simple sample control; thereby applicable to the normal cell and cancer cell discrimination.

• Proceedings of the IEEK Conference
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• 2003.07c
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• pp.2887-2890
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• 2003

This paper describes the possibility of analyzing gait pattern from the variation of the lower leg electrical impedance. This impedance is measured by the four-electrode method. Two current electrodes are applied to the thigh, knee, and foot, and two potential electrodes are applied to the lateral, medial, and posterior position of lower leg. The correlation coefficients of the joint angle and the impedance change from human leg movement was obtained using electrogoniometer and 4ch impedance measurement system developed in this study. We found the optimal electrode position for ankle, knee and hipjoint movements based on high correlation coefficient, least interference, and maximum magnitude of impedance change. The correlation coefficients of the ankle, knee, and the hip movements -0.87, 0.957 and 0.80. respectively. From such features of the lower leg impedance, it has been made clear that different movement patterns exhibit different impedance patterns and impedance level. This system showed possibility that lower leg movement could be easily measured by impedance measurement system with a few skin-electrodes.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2006.05a
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• pp.693-696
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• 2006

In this study, we made the system to measure variation of blood flow using bio-electrical impedance analysis method. The system, which could measure variation of impedance according to pressure change by artificial pressure, consists of pressure measurement and impedance measurement by 4-electrode method. Pressure measurement splits into semiconducting pressure sensor and electronic circuit for processing output signal. In addition, impedance measurement splits into constant current source circuit and lock-in amplifier for detection impedance signal. We experimented feature of impedance measurement using standard resistance to evaluate the system characteristic. As well as, we experimented to estimate variation of blood flow by measuring impedance and blood flow resistance ratio using mean arterial pressure and variation of blood flow with experimental group. As result of this study, blood flow resistance ratio and variation of blood flow were definitely in inverse proportion and were -0.96776 as correlation coefficient by correlation analysis.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.21 no.8
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• pp.776-781
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• 2008

In this study, ubiquitous health care system attaching in chair to monitor ECG for health care was developed at the unconsciousness state. The system conveniently and simple measured ECG at non-consciousness. We measured the contact impedance to skin-electrode of metal mesh electrodes of the system. Contact impedance enable the electrode to use for ECG measurement. The results are that the impedance of the metal mesh electrodes according to sizes is low when the size is 4$cm^2$. As the result, when the size of the metal mesh electrode is 4$cm^2$, the electrode is fit for ECG measurement. We can acquired by positing the arm on the metal mesh electrode. The ECG signal was detected using a high-input-impedance bio-amplifier, and then passed filter circuitry. The measured signal transmitted to a PC through the bluetooth wireless communication and monitored. Data of the non-constrained ECG system attaching in chair is noise-data when comparing metal mesh electrode with the Ag/Agcl electrode but the data is significant to monitor ECG for check the body state.