• Bulletin of the Korean Chemical Society
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• v.30 no.12
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• pp.2905-2908
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• 2009

Immuno-sensing for high accurate and selective sensing was performed by fluorescence spectroscopy and surface plasmon resonance (SPR), respectively. Engineered assembly of two fluorescent quantum dots (QDs) with bovine serum albumin (BSA) and anti-BSA was fabricated in PBS buffer for fluorescence analysis of fluorescence resonance energy transfer (FRET). Furthermore, the same bio-moieties were immobilized on Au plates for SPR analysis. Naturally-driven binding affinity of immuno-moieties induced FRET and plasmon resonance angle shift in the nanoscale sensing system. Interestingly, the sensing ranges were uniquely different in two systems: e.g., SPR spectroscopy was suitable for highly accurate analysis to measure in the range of 10$^{-15{\sim}-10$ng/mL while the QD fluorescent sensing system was relatively lower sensing ranges in 10$^{-10{\sim}-6$ng/mL. However, the QD sensing system was larger than the SPR sensing system in terms of sensing capacity per one specimen. It is, therefore, suggested that a mutual assistance of FRET and SPR combined sensing system would be a potentially promising candidate for high accuracy and reliable in situ sensing system of immune-related diseases.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.7
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• pp.750-753
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• 2016

Quorum sensing (QS) is a bacterium-to-bacterium cell communication mechanism allowing bio-cell network construction but such mechanism is not well defined yet. We construct a QS-based multiple access network (MAN) and then numerically analyse its average uplink channel capacity as well as BER performance over diffusion-based 3-D molecular communication channels.

• Journal of Sensor Science and Technology
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• v.26 no.5
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• pp.342-347
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• 2017

We present a precision instrument amplifier (IA) designed for bio-potential acquisition. The proposed IA employs a capacitively coupled instrument amplifier (CCIA) structure to achieve a rail-to-rail input common-mode range and low gain error. A positive feedback loop is applied to boost the input impedance. Also, DC servo loop (DSL) with pseudo resistors is adopted to suppress electrode offset for bio-potential sensing. The proposed amplifier was designed in a $0.18{\mu}m$ CMOS technology with 1.8V supply voltage. Simulation results show the integrated noise of $1.276{\mu}Vrms$ in a frequency range from 0.01 Hz to 1 KHz, 65dB SNR, 118dB CMRR, and $58M{\Omega}$ input impedance respectively. The total current of IA is $38{\mu}A$. It occupies $740{\mu}m$ by $1300{\mu}m$ including the passive on-chip low pass filter.

• Molecules and Cells
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• v.43 no.6
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• pp.530-538
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• 2020

The Gustatory system enables animals to detect toxic bitter chemicals, which is critical for insects to survive food induced toxicity. Cucurbitacin is widely present in plants such as cucumber and gourds that acts as an anti-herbivore chemical and an insecticide. Cucurbitacin has a harmful effect on insect larvae as well. Although various beneficial effects of cucurbitacin such as alleviating hyperglycemia have also been documented, it is not clear what kinds of molecular sensors are required to detect cucurbitacin in nature. Cucurbitacin B, a major bitter component of bitter melon, was applied to induce action potentials from sensilla of a mouth part of the fly, labellum. Here we identify that only Gr33a is required for activating bitter-sensing gustatory receptor neurons by cucurbitacin B among available 26 Grs, 23 Irs, 11 Trp mutants, and 26 Gr-RNAi lines. We further investigated the difference between control and Gr33a mutant by analyzing binary food choice assay. We also measured toxic effect of Cucurbitacin B over 0.01 mM range. Our findings uncover the molecular sensor of cucurbitacin B in Drosophila melanogaster. We propose that the discarded shell of Cucurbitaceae can be developed to make a new insecticide.

• Journal of agriculture & life science
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• v.53 no.3
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• pp.147-157
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• 2019

In this study, we tried to find out the most appropriate pre-processing method and to verify the feasibility of developing a low-price sensing system for predicting the hardy kiwis sugar content based on VNIRS and subsequent spectral analysis. A total of 495 hardy kiwi samples were collected from three farms in Muju, Jeollabukdo, South Korea. The samples were scanned with a spectrophotometer in the range of 730-2300 nm with 1 nm spectral sampling interval. The measured data were arbitrarily separated into calibration and validation data for sugar content prediction. Partial least squares (PLS) regression was performed using various combinations of pre-processing methods. When the latent variable (LV) was 8 with the pre-processing combination of standard normal variate (SNV) and orthogonal signal correction (OSC), the highest R2 values of calibration and validation were 0.78 and 0.84, respectively. The possibility of predicting the sugar content of hardy kiwi was also examined at spectral sampling intervals of 6 and 10 nm in the narrower spectral range from 730 nm to 1200 nm for a low-price optical sensing system. The prediction performance had promising results with R2 values of 0.84 and 0.80 for 6 and 10 nm, respectively. Future studies will aim to develop a low-price optical sensing system with a combination of optical components such as photodiodes, light-emitting diodes (LEDs) and/or lamps, and to locate a more reliable prediction model by including meteorological data, soil data, and different varieties of hardy kiwi plants.

• Proceedings of the KSRS Conference
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• 1998.09a
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• pp.393-398
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• 1998

• Proceedings of the Korean Vacuum Society Conference
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• 2008.02a
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• pp.132-132
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• 2008

• Journal of the Korean Solar Energy Society
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• v.28 no.6
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• pp.58-63
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• 2008

It is essential to investigate the structure and the main characteristic of Home USN (Ubiquitous Sensor Network) technologies in built ubiquitous environment while designing bio-sensors. For this study, Thermistor elements and Thermopile black body have been selected to implement ubiquitous technologies for bio-sensors and wireless network such as WiBro has been used to transfer sensing data to the BSN (Bio-Sensor Network) gateway. It is certain that efficiency of ubiquitous space design is improved if main components of each specific sensor network are analyzed precisely in digital way and corresponding communication modules are prepared accordingly. Ubiquitous technology, in conclusion, has to be applied not only with systematical mechanism or electronic setting but in human-centered atmosphere as well, keeping with deep consideration for bio-housing service factors in eco-friendly surrounding.

• 한국HCI학회:학술대회논문집
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• 2008.02a
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• pp.13-18
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• 2008

In these days, wearable and mobile physiological sensing devices have been studied according to the increasing interest on the healthy and wellbeing life. However, these sensing devices display just the sensing results, such as heart rate, skin temperature, and its daily records. In this work, we propose the novel type of mobile physiological sensing device which deliver the user comfortable grabbing feeling. In addition, we indicate the personalized physiological signal analysis result which be concluded by the different analysis results according to the person to person. In order to verify this sensing device, we collect the data set from 4 different users during a week and measure the physiological signal such as heart rate, hand temperature, and skin conductance. And we observe the result how the analysis results shows the difference between the users. We expect that this work can be applied in the various health care applications in the near future.

• Journal of Sensor Science and Technology
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• v.31 no.3
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• pp.139-144
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• 2022

Advanced tactile sensors are receiving significant attention in various industries such as extended reality, electronic skin, organic user interfaces, and robotics. The capabilities of advanced tactile sensors require a variety of functions, including position sensing, pressure sensing, and material recognition. Moreover, they should comsume less power and be bio-friendly with human contact. Recently, a tactile sensor based on the triboelectrification effect was developed. Triboelectric tactile sensors have the advantages of wide material availability, simple structure, and low manufacturing cost. Because they generate electricity by contact, they have low power consumption compared to conventional tactile sensors such as capacitive and piezoresistive. Furthermore, they have the ability to recognize the contact material as well as execute position and pressure sensing functions using the triboelectrification effect. The aim of this study is to introduce the progress of research on triboelectrification-based tactile sensors with various functions such as position sensing, pressure sensing and contact material recognition.