• Transactions of the KSME C: Technology and Education
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• v.1 no.1
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• pp.21-26
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• 2013

In this paper, we introduced various 3D printing technology and it's application on tissue engineering and regenerative medicine. Using the 3D printing technology, Korea Institute of Machinery and Materials (KIMM) has developed 3D bio-printing system. Various 3D tissue engineered scaffolds have been fabricated by the 3D bio-printing system. Cell printing system has been also developed and it is the fundamental technology for organ regeneration in tissue engineering and regenerative medicine.

• Journal of Technologic Dentistry
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• v.40 no.3
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• pp.115-123
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• 2018

Purpose: The purpose of this study was establishing process of manufacturing dental prosthesis by using eZIS system(DDS Inc.,Korea). Methods: To evaluate accuracy verification, the test was practiced two ways. First, Comparison of 3D printing models and stone models was practiced by using 3D superimposing software. #36 prepared master model was scanned by eZIS system and three 'Veltz3D' 3D printing models and three 'Bio3D' 3D printing models were manufactured. three stone models were manufactured by conventional impression technique. Second, Fitness test was practiced. the 3D printing models and the stone models was compared by manufacturing same resin crown. #36 prepared master model was scanned 9 times and manufactured (milled) 9 resin crowns by eZIS system. These crowns were cemented three 'Veltz3D' 3D printing models, three 'Bio3D' 3D printing models and three stone models. These crowns were sliced mesiodistal axis and gaps were measured by digital microscope. Results: The average accuracy of Bio3D models were 65.75%. Veltz3D(Hebsiba) models were 60.11% Stone models were 41.00%. Conclusion : This study results showed 3D printing model is similar with stone model. So it was under clinical allow, didn't affect final dental prothesis. There were no significant differences in the appearance of the three types of milling crowns.

• Elastomers and Composites
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• v.52 no.2
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• pp.99-104
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• 2017

Due to the depletion of fossil oil and the increasing oil price, bio-plastic is currently topical. Bio-based plastics are synthesized from plant resources, unlike conventional petroleum-based counterparts. Therefore, the former minimizes global warming and reduces carbon dioxide emission. Fossil polycarbonate (PC)has good mechanical and optical properties, but its synthesis requires bisphenol-A and phosgene gas, which are toxic to humans. To address these problems, the fused deposition 3D printing process (hereafter, FDM) is studied using environmentally-friendly and high-strength bio-based PC. A comparisonof the environmental impact and tensile strength of fossil PC versus bio-based PC is presented herein, demonstrating that bio-based PC is more environmentally-friendly with higher tensile strength than fossil PC. The advantages of bio-based PC are applied in the FDM process for the fabrication of environmentally-friendly baby toys.

• Journal of the Semiconductor & Display Technology
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• v.20 no.3
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• pp.125-130
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• 2021

Scaffold is used to produce bio sensor. Scaffold is required high dimensional accuracy. 3D printer is used to manufacture scaffold. 3D printer can't detect defect during printing. Defect detection is very important in scaffold printing. Real-time defect detection is very necessary on industry. In this paper, we proposed the method for real-time scaffold defect detection. Real-time defect detection model is produced using CNN(Convolution Neural Network) algorithm. Performance of the proposed model has been verified through evaluation. Real-time defect detection system are manufactured on hardware. Experiments were conducted to detect scaffold defects in real-time. As result of verification, the defect detection system detected scaffold defect well in real-time.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.5
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• pp.143-148
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• 2018

3D printing has been expanding beyond the bio/nano field to the automobile and aviation industries. 3D-printing technology has to overcome real problems to have economic value compared to its unlimited usability. Typically, the difference in mechanical strength along the lamination direction requires sufficient research to ensure reliability. In this paper, we study the anisotropic properties of ABS based on the stacking method of FDM 3D printing. Specifically, the mechanical properties of ABS material are determined through a tensile test and 3-point bending test, and the in-plane orthotropic properties are ascertained.

• Journal of Biomedical Engineering Research
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• v.39 no.1
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• pp.22-29
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• 2018

Intervertebral disc(IVD) mainly consists of Annulus fibrosus(AF) and Nucleus pulposus(NP), playing a role of distributing a mechanical load on vertebral body. IVD tissue engineering has been developed the methods to achieve anatomic morphology and restoration of biological function. The goal of present study is to identify the possibilities for creating a substitute of IVD the morphology and biological functions are the same as undamaged complete IVD. To fabricate the AF and NP combine biphasic IVD tissue, AF tissue scaffolds have been printed by 3D bio-printing system with natural biomaterials and NP tissues have been prepared by scaffold-free culture system. We evaluated whether the combined structure of 3D printed AF scaffold and scaffold-free NP tissue construct could support the architecture and cell functions as IVD tissue. 3D printed AF scaffolds were printed with 60 degree angle stripe patterned lamella structure(the inner-diameter is 5mm, outer-diameter is 10 mm and height is 3 mm). In the cytotoxicity test, the 3D printed AF scaffold showed good cell compatibility. The results of histological and immunohistochemical staining also showed the newly synthesized collagens and glycosaminoglycans, which are specific makers of AF tissue. And scaffold-free NP tissue actively synthesized glycosaminoglycans and type 2 collagen, which are the major components of NP tissue. When we combined two engineered tissues to realize the IVD, combined biphasic tissues showed a good integration between the two tissues. In conclusion, this study describes the fabrication of Engineered biphasic IVD tissue by using enable techniques of tissue engineering. This fabricated biphasic tissue would be used as a model system for the study of the native IVD tissue. In the future, it may have the potential to replace the damaged IVD in the future.

• JSTS:Journal of Semiconductor Technology and Science
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• v.7 no.3
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• pp.133-139
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• 2007

Future MEMS systems will be composed of larger varieties of devices with very different functionality such as electronics, mechanics, optics and bio-chemistry. Integration technology of heterogeneous devices must be developed. This article first deals with the current development trend of new fabrication technologies; those include self-assembling of parts over a large area, wafer-scale encapsulation by wafer-bonding, nano imprinting, and roll-to-roll printing. In the latter half of the article, the concept towards the heterogeneous integration of devices and functionality into micro/nano systems is described. The key idea is to combine the conventional top-down technologies and the novel bottom-up technologies for building nano systems. A simple example is the carbon nano tube interconnection that is grown in the via-hole of a VLSI chip. In the laboratory level, the position-specific self-assembly of nano parts on a DNA template was demonstrated through hybridization of probe DNA segments attached to the parts. Also, bio molecular motors were incorporated in a micro fluidic system and utilized as a nano actuator for transporting objects in the channel.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.2
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• pp.351-356
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• 2014

Although the demand for histopathological examinations has been increasing, medical accidents in management of specimens also have been increasing because most of the examinations are processed manually which can cause careless handing, confusing information and mismatching during the procedure. In the future, histopatological examination will be used frequently for handing incurable diseases and verification of new drug. Thus, efficient and error-free management system for handling personalized medical history and test results is infallibly necessary. In this paper, I have proposed an integrated printing system for informatization of histopathological examination that support the u-Healthcare environment based on RFID in near future. The proposed system supports systematization of whole examination process and information of pathological samples. This system will contribute to reduction of costs, improvement of operational efficiency, and mostly fundamental prevention of medical accidents.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.7 s.184
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• pp.168-176
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• 2006

Nowadays, Three dimensional printing (3DP) technique that is one of solid freeform fabrication (SFF) technology has been notable issue, and has been applied by various fields. The SFF system can fabricate three dimensional objects of solid freeform with high speed and low cost using ink jet printing technology. In this research, a SFF system to analyze 3DP process technology is developed. We applied sliding mode control with sliding perturbation observer (SMCSPO) algorithm and minimized position error to the developed SFF system. We analyzed and optimized process variables such as jetted volume, layer thickness, powder bed and so on experimentally. Also. the dimensional error of a developed SFF system is evaluated. Finally, the feasibility of application to bio manufacturing is presented through successful fabrication of teeth and cranium model.

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.05a
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• pp.10.1-10.1
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• 2011

Energy harvesting technologies converting external sources (such as thermal energy, vibration and mechanical energy from the nature sources of wind, waves or animal movements) into electrical energy is recently a highly demanding issue in the materials science community for making sustainable green environments. In particular, fabrication of usable nanogenerator attract the attention of many researchers because it can scavenge even the biomechanical energy inside the human body (such as heart beat, blood flow, muscle stretching, or eye blinking) by converging harvesting technology with implantable bio-devices. Herein, we describe procedure suitable for generating and printing a lead-free microstructured $BaTiO_3$ thin film nanogenerator on plastic substrates to overcome limitations appeared in conventional flexible ferroelectric devices. Flexible $BaTiO_3$ thin film nanogenerator was fabricated and the piezoelectric properties and mechanically stability of ferroelectric devices were characterized. From the results, we demonstrate the highly efficient and stable performance of $BaTiO_3$ thin film nanogenerator and the integration of bio-eco-compatible ferroelectric materials may enable innovative opportunities for artificial skin and energy harvesting system.