• Title/Summary/Keyword: Beta Coefficient

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Study of the Percutaneous Absorption, Stability and Physicochemical Properties of $OMP-{\beta}-CD$ Inclusion Complex ($OMP-{\beta}-CD$ 포접화합물의 물리화학적 성질, 안정성 및 피부 투과 실험)

  • Lee, Sang-Young;Lee, Gye-Won;Choi, Hyun-Soon;Jee, Ung-Kil
    • Journal of Pharmaceutical Investigation
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    • v.27 no.4
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    • pp.271-277
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    • 1997
  • Because omeprazole(OMP) is very unstable in aqueous condition, $OMP-{\beta}-CD$, the inclusion complex of OMP and ${\beta}-cyclodextrin({\beta}-CD)$ was made and physicochemical properties of it were compared with those of OMP. Skin permeability of OMP and $OMP-{\beta}-CD$ in propylene glycol vehicle and the reciprocal action of ${\beta}-CD$ with various enhancers were examined through hairless mouse. Adhesive patches were prepared with polyisobutylene and the skin permeability and stability of OMP were investigated. The inclusion complex showed higher solubility and lower partition coefficient than OMP itself. DMSO, 1-methyl 2-pyrrolidone and sodium cholate had an enhancing effect. However ethanol and polysorbate 80 hardly showed the enhancing effect of OMP. When sodium lauryl sulfate and sodium cholate as enhancer were added in patch, the former case showed higher permeability of OMP.

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Mixing Rules of Young's Modulus, Thermal Expansion Coefficient and Thermal Conductivity of Solid Material with Particulate Inclusion

  • Hirata, Yoshihiro;Shimonosono, Taro
    • Journal of the Korean Ceramic Society
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    • v.53 no.1
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    • pp.43-49
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    • 2016
  • This analyzed a Young's modulus (E), a thermal expansion coefficient (TEC, ${\beta}$) and a thermal conductivity (${\kappa}$) of the material with simple cubic particulate inclusion using two model structures: a parallel structure and a series structure of laminated layers. The derived ${\beta}$ equations were applied to calculate the ${\beta}$ value of the W-MgO system. The accuracy was higher for the series model structure than for the parallel model structure. Young's moduli ($E_c$) of sintered porous alumina compacts were theoretically related to the development of neck growth of grain boundary between sintered two particles and expressed as a function of porosity. The series structure model with cubic pores explained well the increased tendency of $E_c$ with neck growth rather than the parallel structure model. The thermal conductivity of the three phase system of alumina-mullite-pore was calculated by a theoretical equation developed in this research group, and compared with the experimental results. The pores in the sintered composite were treated as one phase. The measured thermal conductivity of the composite with 0.5-25% porosity (open and closed pores) was in accordance with the theoretical prediction based on the parallel structure model.

Development of Lactose-hydrolyzed Milk with Low Sweetness Using Nanofiltration

  • Choi, S.H.;Lee, S.-B.;Won, H.-R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.6
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    • pp.989-993
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    • 2007
  • A lactose-hydrolyzed milk with low sweetness was developed using nanofiltration. Raw milk was treated with 0.03% ${\beta}$-galactosidase at $4^{\circ}C$ for 24 h to hydrolyze lactose partially. The resultant lactose-hydrolyzed milk containing 0.43% lactose was then concentrated using a nanofiltration membrane to reach concentration factor of 2.13. The concentration factors and coefficients of retention of milk components in nanofiltration were determined. The concentration factor of milk fat was 2.20 which was the highest of the milk components. The coefficient of retention of calcium and riboflavin was 0.96 and 0.76, respectively. However, the coefficient of retention of glucose, galactose, and sodium was 0.21, 0.15, and 0.22, respectively. Raw milk was treated with 0.1% ${\beta}$-galactosidase at $4^{\circ}C$ for 40 h to hydrolyze lactose fully and then concentrated to reach a concentration factor of 1.6 by using nanofiltration. The concentrated milk was reconstituted with water. The lactose-hydrolyzed milk had sweetness similar to milk. The compositional ratios of crude protein, calcium, sodium, and riboflavin of lactose-hydrolyzed nanofiltrated milk to those of raw milk were 99%, 97%, 77%, and 80%, respectively. This study showed that nanofiltration of lactose-hydrolyzed milk to remove galactose and glucose did not cause significant loss of calcium. The lactose-hydrolyzed nanofiltrated milk contained 0.06% lactose and had sweetness similar to milk.

Comparison of Three Binomial-related Models in the Estimation of Correlations

  • Moon, Myung-Sang
    • Communications for Statistical Applications and Methods
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    • v.10 no.2
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    • pp.585-594
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    • 2003
  • It has been generally recognized that conventional binomial or Poisson model provides poor fits to the actual correlated binary data due to the extra-binomial variation. A number of generalized statistical models have been proposed to account for this additional variation. Among them, beta-binomial, correlated-binomial, and modified-binomial models are binomial-related models which are frequently used in modeling the sum of n correlated binary data. In many situations, it is reasonable to assume that n correlated binary data are exchangeable, which is a special case of correlated binary data. The sum of n exchangeable correlated binary data is modeled relatively well when the above three binomial-related models are applied. But the estimation results of correlation coefficient turn to be quite different. Hence, it is important to identify which model provides better estimates of model parameters(success probability, correlation coefficient). For this purpose, a small-scale simulation study is performed to compare the behavior of above three models.

On Estimating Good Reliability Coefficient when the Test is Split into Several Formats of Subtests and Standardizing the Raw Score, whose Distribution is Departed from Normality. (부문항이 분할된 고사에서 우량한 신뢰도 계수추경과 그 평가치 분포의 정규화)

  • 홍석강
    • The Mathematical Education
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    • v.41 no.1
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    • pp.109-126
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    • 2002
  • In this thesis. we estimated the good reliability coefficient ${\beta}$$\sub$k/ that is unbiased, consistent and more efficient than Cronbach's ${\alpha}$$\sub$k/ in splitting of a test into several formats of subtests and several properties of ${\beta}$$\sub$k/ are also represented. The tables of coefficients of skewness and kurtosis are represented to test the significance of departures from normality. We got the cumulative normal plots of z'from the distribution which is departed from normality using the Bock's approximation procedure and we finally enumerated the transformed standardized scores z'and a new raw score X' which enable us to proceed further evaluation procedures depending on our assessment policy.

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A Sediment Concentration Distribution Based on a Revised Prandtl's Mixing Theory

  • Jung, Kwan-Sue
    • Korean Journal of Hydrosciences
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    • v.8
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    • pp.1-17
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    • 1997
  • Prandtl's mixing length theory was modified to obtain a power velocity distribution in which the coefficient and the exponent are variable over a range from : $$ A simple suspended-sediment concentration distribution was developed from the modified velocity distribytion : $ With nominal values of $\beta$=1.0, $\kappa$=0.4 and visual accumulation tube values of the fall velocity, the comparison between the theory and field measurements by the USGS on the Rio Grande is fair. Doubling the value of the exponent results in a good comparison. Further researches are needed for choosing the values of $\beta$, $\kappa$, and fall velocity values, and consideration on the effects of large-scale turbulence and secondary flows are necessary for them. In a pragmatic sense, on any gaging sites the close analysis of very detailed measurements can establish its specific coefficient and exponent.

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Phase Transformation and Thermoelectric Properties of Fe0.92Mn0.08Si2 Prepared by Mechanical Alloying (기계적 합금화로 제조된 Fe0.92Mn0.08Si2의 상변화 및 열전 특성)

  • Kim, Young-Seob;Cho, Kyung-Won;Kim, Il-Ho;Ur, Soon-Chul;Lee, Young-Geun
    • Korean Journal of Materials Research
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    • v.13 no.5
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    • pp.292-296
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    • 2003
  • In an attempt to enhance phase transformation and homogenization of Mn-doped $FeSi_2$, mechanical alloying of elemental powders was applied. Cold pressing and sintering in vacuum were carried out to produce a dense microstructure, and then isothermal annealing was employed to induce a phase transformation to the $\beta$-$FeSi_2$semiconductor. Phase transitions in this alloy system during the process were investigated by using XRD, EDS and SEM. As-milled powders after 100 h of milling were shown to be metastable state. As-sintered iron silicides consisted of untransformed mixture of $\alpha$-$Fe_2$$Si_{5}$and $\varepsilon$-FeSi phases. $\beta$-$FeSi_2$phase transformation was induced by subsequent isothermal annealing at $830^{\circ}C$, and near single phase of $\beta$-$FeSi_2$was obtained after 24 h of annealing. Thermoelectric properties in terms of Seebeck coefficient, and electrical conductivity were evaluated and correlated with phase transformation. Seebeck coefficient electrical resistivity and hardness increased with increasing annealing time due to $\beta$ phase transformation.

Effects of Oral Health Impact Profile (OHIP) on Depression and Quality of Life among Community-dwelling Korean Elderly Persons (노인의 구강건강 영향지수가 우울과 삶의 질에 미치는 영향)

  • Lee, Hung Sa;Kim, Chunmi
    • Research in Community and Public Health Nursing
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    • v.23 no.3
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    • pp.338-346
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    • 2012
  • Purpose: The purpose of this study was to examine the association between oral health impact profile, depression and quality of life among community-dwelling elderly persons in South Korea. Methods: The design of this research was cross-sectional descriptive study. The participants were 266 community-dwelling individuals aged 65 and older. Data were collected from November 20 to December 20, 2011. The measurements for assessing the subjects' oral health, depression, quality of life were OHIP-14, GDS-SF and QOL. Data were collected using self-administered or interviewer-administered questionnaires. Collected data were analyzed using descriptive statistics, Pearson's correlation coefficient and stepwise multiple regression. Results: The participants' mean age was 77.68, and 86.5% were female, 42.9% were living-alone elders. Pearson's correlation coefficient analysis found that oral health impact profile was significantly associated with depression (r=-.622, p<.001), QOL (r=-.400, p<.001), number of disease (r=.298, p<.001), age (r=.198, p=.002), education (r=-.149, p=.015), eating habit (r=.185, p=.003). The QOL was explained 54.7% by depression (${\beta}$=-.619), oral health impact profile (${\beta}$=-.127), number of benefited welfare service (${\beta}$=.235), perceived health (${\beta}$=-.327), eating habit (${\beta}$=-.094) using stepwise multiple regression analysis. Conclusion: These results indicate that the intervention program of oral health promotion for community-dwelling elders is needed from now on.

Empirical Study on Effects of Disk Shape Filler Content and Orientation on Thermal Expansion Coefficient of PP Composites (판상형 충전제의 함량과 배향에 따른 PP복합체의 열팽창계수 영향 연구)

  • Lee, Yong-Hyun;Jeoung, Sun-Kyoung;Hwang, Hyo-Yeon;Lee, Seung-Goo;Lee, Kee-Yoon
    • Polymer(Korea)
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    • v.36 no.3
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    • pp.281-286
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    • 2012
  • Experimental study was performed regarding the effects of disc-like filler orientation and contents on the coefficient of thermal expansion (CTE) of polypropylene composites using the three dimensional ellipsoids ($a_1$ > $a_2$ > $a_3$) analyzed by two aspect ratios(${\rho}_{\alpha}=a_1/a_3$and ${\rho}_{\beta}=a_1/a_2$). Measured data were compared with the theoretical approaches proposed by Lee et al. Mica and talc were useed as disk-like fillers in the composites. As experimental results, ${\alpha}_{11}/{\alpha}_m$ decreased down to ca. 0.56 with mica content of 20 wt% and the aspect ratios, ${\rho}_{\alpha}=13.5$, ${\rho}_{\beta}=1.8$. However, ${\alpha}_{33}/{\alpha}_m$ increased to more than 1. In the case of talc, ${\alpha}_{11}/{\alpha}_m$ decreased to ca. 0.63 with 20 wt% and ${\rho}_{\alpha}=3.7$, ${\rho}_{\beta}=1.4$. Finally, the longitudinal CTEs (${\alpha}_{11}$) of polypropylene composites decreased as filler contents increased, but normal CTE (${\alpha}_{33}$) increased in the low filler contents like the theory.

The Effect of Department of Emergency Medical Service Students' Knowledge and Attitudes toward Tuberculosis Infection Prevention Behaviors (응급구조학과 학생들의 결핵에 대한 지식 및 태도가 결핵감염 예방행위에 미치는 영향)

  • Moon, Sung-Mo;Kim, Duk-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.259-266
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    • 2019
  • This study aimed to identify factors that had an influence on preventive behaviors of Emergency Medical Service students against tuberculosis to promote their preventive behavior. The subjects of the study were 314 students studying emergency medical service from one 4-year college and two 3-year colleges in Jeollabukdo and they were researched with the use of a questionnaire from June 25, to July 6, 2018. For a statistical analysis of the data obtained, this study used SPSS 18.0 and conducted a t-test, an ANOVA, a Pearson's correlation coefficient and a multi-regression test to analyze the data. Pearson's correlation coefficient analysis showed that the preventive behavior levels was significantly correlated with knowledge of tuberculosis (r = 0.268, p <0.001) and attitude (r = 0.394, p<0.001). As results of the multi-regression test, the higher the knowledge of tuberculosis(${\beta}=0.152$, p<0.001) and the higher the attitude(${\beta}=0.052$, p<0.001), the higher the preventive behavior levels. In addition, Students who have experienced tuberculosis in their own or relative's relatives have a high level of prevention behavior(${\beta}=-0.186$, p=0.001). Therefore, it is suggested that organized and consistent education programs to promote knowledge on tuberculosis, change negative perception on it and improve preventive behavior levels should be developed and provided.