• Title/Summary/Keyword: Behavioral Experiment

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Effects of Psychotropic Agents on Motor Activity in Mice (향정신성약물이 마우스 자발운동에 미치는 영향)

  • Woo, Haing-Won
    • The Korean Journal of Pharmacology
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    • v.11 no.1 s.17
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    • pp.55-60
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    • 1975
  • An animal which is placed in a new environment displays a complex behavioral pattern consisting of locomotion, grooming and rearing. This behavioral pattern is influenced by endogenous and exogenous stimuli, such as hormonal secretion, level of neurohumoral transmitters, drugs and light. It is widely known that the most tranquilizers depressed spontaneous motor activity although their mechanisms of action were different, while antidepressants stimulated except imipramine which showed various action. Until the present time, the hole-board apparatus, which gives rather subjective data, has been used extensively to study the effects of drugs on general activity and exploratory behavior in mice. Recently a new apparatus for mobility measurements, called a 'Selective Activity Meter' has been introduced. This instrument supposedly produces more objective data on activity and behavior. The purpose of the present experiment was to study the influence of psychotropics on motor activity using the Selective Activity Meter. In the experiment, various psychotropic agents such as major tranquilizers(chlorpromazine, haloperidol); minor tranquilizers(meprobamate, diazepam); and antidepressants(amphetamine, imipramine) were used. In each experiment, the drug was administered to five mice and their activity was recorded. Each experiment was run five or more times and the results are based on the mean of each trial. The results are summarized as follows: 1. The group of mice treated with chlorpromazine showed markedly inhibited motor activity in comparison with controls and the inhibitory action of chlorpromazine was shown to be more intense than any of the other drugs used in the test. Haloperidol administration yielded similar results until 60 minutes, but mice showed less inhibition of motor activity than with chlorpromazine after 90 minutes. 2. In the group treated with diazepam, there was strong inhibition of motor activity until 30 minutes, but after 60 minutes the mice showed less inhibition than with chlorpromazine. In the meprobamate group, motor activity was inhibited in a manner similar to that of other tranquilizers, but the inhibition was less than that of diazepam. 3. In the group treated with imipramine, the inhibition developed gradually after ten minutes. 4. The effects of amphetamine did not appear until 30 minutes after administration, but then there was a significant increase in the motor activity.

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The Effects of a Cognitive Behavioral Gratitude Program on Gratitude Disposition and Happiness for Elementary School Students (인지행동적 감사프로그램이 초등학생의 감사성향과 행복감에 미치는 효과)

  • Yun, Hae-Jeong;Cho, Bung-Hwan
    • The Korean Journal of Elementary Counseling
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    • v.10 no.1
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    • pp.1-17
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    • 2011
  • The purpose of this study was to review of the psychology experiment researches in gratitude and the definition of gratitude, the effects of gratitude on happiness and mental health was examined. And examine the effectiveness of the cognitive behavioral gratitude program on gratitude disposition and happiness for elementary school students. The subject group consists of 2 classes from the 5th grade at G elementary school in Daejeon. For the experimental group, total 10 sessions of a cognitive behavioral gratitude program were applied once a week for 10 weeks, while there's no special treatment to the control group, The result were as follows. Cognitive behavioral gratitude program is shown to very effective in improving on gratitude disposition and happiness for elementary school students.

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The Effects of Time Management Behavioral Therapy Program on Self-Esteem, Stress Coping of School Maladjusted Adolescents (시간관리 행동치료 프로그램이 학교부적응 청소년들의 자아존중감, 스트레스 대처에 미치는 효과)

  • Yi, Yeon-Duk;Hwang, Gi-Chul
    • Journal of Digital Convergence
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    • v.11 no.10
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    • pp.517-526
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    • 2013
  • This study was conducted to investigate the effects of time management behavioral therapy program on self-esteem, stress coping of school maladjusted adolescents. Experiment was conducted with 8 school maladjusted adolescents who were helped in living facilities. Time management behavioral therapy was applied to adolescents 16 weeks. To achieve the purpose of this study, self-esteem scale and stress coping scale were analyzed and compared before and after intervention. The results of this study were as follows: School maladjusted adolescents showed the significant increase in self-esteem. and School maladjusted adolescents showed the significant increase in active and passive coping of stress by intervention. It was proven to have positive effects on stress coping by intervention in a short time. Through the results of this study, time management behavioral therapy program was proven to have positive effects on self-esteem, stress coping of school maladjusted adolescents.

Studies on the Behavioral Pharmacology of the Antidepressant Effect of Polygala japonica Houtt (영신초(靈神草)의 항우울 효과에 대한 행동약리학적 연구)

  • Lee, Eun-Kyung;Chung, Dae-Kyoo
    • Journal of Oriental Neuropsychiatry
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    • v.22 no.2
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    • pp.129-146
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    • 2011
  • Objectives : The purpose of this study was to characterize the putative antidepressant and antianxiolytic effects of the 70% ethanol extract of Polygala japonica(EEPJ) using animal's behavioral experiment in mice. Methods : The effect of EEPJ on the anxioty and depressive disorder was investigated via mice's behavioral experiment like Elevated plus-maze, Horizontal wire test, Open field test, Forced swimming test, Tail suspension test, and it was happen via any mechanism by WAY 100635, a 5-HT1A receptor antagonist and by Flumazenil, a GABAA antagonist Results : 1. In the EPM, single treatments of the EEPJ(200 and 400mg/kg) had usefully antianxiolytic effects versus vehicle, which was medicated via the serotonergic nervous system. 2. In the HWT, single treatments of the EEPJ were no changes in the myorelaxant effects versus vehicle. 3. In the OFT, single treatments of the EEPJ were no changes in the locomotor activity versus vehicle. 4. In the FST, single treatments of the EEPJ(50mg/kg) significantly reduced the immobility time versus vehicle. 5. In the TST, single treatments of the EEPJ(50mg/kg) significantly reduced the immobility time versus vehicle. Conclusions : These results indicate that EEPJ is an effective antidepressant and antianxiolytic activity in mice, and it might be usefully applied for prevention and treatment of depressive disorder through evolutive study like development of various experimental models.

Prefrontal alpha EEG Asymmetry and Interior Color Affect Based on Types of Behavioral and Affective System (행동·감정체계 유형에 따른 전전두엽 알파파 비대칭 특성 및 실내공간 색채감정)

  • Ha, Ji-Min;Park, Soobeen
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.9
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    • pp.55-66
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    • 2018
  • This study aims to propose color affective model of indoor space by evaluating subjects' physiological responses according to the types of behavioral and affective system. 99 subjects(44 females, 55 males) in their 20s, who had no disorders in visual perception, participated in the experiment. To categorize the subjects based on behavioral and affective system, BAS/BIS scale and Affective scale were used. Color stimuli were composed of five basic colors and three tones: vivid, pale and dull tone of R, Y, G, B, P. For physiological experiment, right and left prefrontal alpha activity was measured to analyze prefrontal EEG asymmetry. Participants were exposed to fifteen color stimuli for 20 seconds each other under the positive and negative emotional condition in a research room with the natural light blocked. The results and conclusion of this study are as follows. Along with factors of behavioral and affective system, cluster analysis was carried out and four types were classified. Type A had high BAS sensitivity, especially high 'drive' trait, and showed high levels of 'anxiety' and 'anger'. Type B had low BAS sensitivity, especially low 'fun seeking' and low 'drive' trait, and showed low levels of 'anxiety' as well as low levels of 'happiness'. Type C had low BIS sensitivity and showed high levels of 'happiness' and low levels of 'sadness'. Type D had high BIS sensitivity and showed high levels of 'lethargy' and 'sadness'. As a result of EEG signal analysis of color stimuli, Type B, Type C, and Type D showed significant differences in prefrontal alpha asymmetry under the negative emotional stimuli. Type B showed more left prefrontal activation in the spaces with pale R and dull G. Type C showed more left prefrontal activation in the spaces with vivid Y and B, pale R, and dull R, G, P. Type D showed more left prefrontal activation in the spaces with vivid Y and P, pale R, Y, P, and dull R, Y, G, B, P. The group of high BAS sensitivity was not influenced by color stimuli under the emotional conditions, whereas the group of high BIS sensitivity was affected by color stimuli under the negative emotional conditions. They showed left prefrontal activation when they were exposed the spaces with vivid, pale, dull tones of Y and P wall.

The Effects of Training in Exercise Rehabilitation on Depressive mood, BPSD in Elderly with Alzheimer's Disease (운동재활훈련이 알츠하이머 노인의 우울정서와 정신행동증상에 미치는 효과)

  • Cho, Sung-Hyoun;Kim, Cheol-Yong
    • Journal of the Korean Society of Physical Medicine
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    • v.7 no.1
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    • pp.37-47
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    • 2012
  • Purpose : The purpose of this study is to examine the effects of training in exercise rehabilitation on depressive emotion, behavioral and psychological symptoms(BPSD) caused by Alzheimer's disease elders. Methods : The subjects of this study were 34 patients with Alzheimer's disease over 65 and assigned randomly into one of two groups, each with 17 people. The experimental group was treated by training in exercise rehabilitation executed 60 minutes, 3 times a week for 8 weeks. The results of the experiment were analyzed using samples t-test along with averages and standard deviations as the statistical methods for data analyses. Results : The results of this study were as follows. First, the experimental group showed statistically significant improvements in the areas of depressive emotion(SGDS) compared to control group. Second, the experimental group showed statistically significant improvements in the severity of behavioral and psychological symptoms and subjective degrees of pain of care givers(NPI-Q) compared to control group. Conclusion : Based on the results of this study, training in exercise rehabilitation have an effect on depressive mood and BPSD in elderly with Alzheimer's disease.

Effects of Red Ginseng on Exercise Capacity and Peripheral Fatigue in Mice

  • Kim, Daehyun;Lee, Byounggwan;Kim, Heejin;Kim, Mikyung
    • Physical Therapy Rehabilitation Science
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    • v.10 no.2
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    • pp.175-184
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    • 2021
  • Objective: Fatigue can decrease both quality of life and work efficiency. Ginseng is one of the most popular herbal treatments for improving personal health, with applications in treating fatigue. However, the exact mechanisms of anti-fatigue effects are still unclear. Thus, we investigated the effect of red ginseng powder (RGP) on exercise capacity and peripheral fatigue using both behavioral and molecular experiments in mice. Design: Four-groups behavioral and molecular experiment. Methods: Male 6-weeks-old ICR mice were treated with distilled water, 100, and 200 mg/kg RGP for 5 days via oral administration. The exercise capacity of each animal group was measured by locomotor activity, rota-rod, hanging wire, and cold swimming tests. Additionally, after performing the treadmill to induce fatigue, lactate expression and molecular experiments were investigated using mice gastrocnemius. Results: Mice treated with RGP exhibited increased exercise capacity in the behavioral tests. Additionally, RGP induced a dose-dependent decrease in lactate levels after high-intensity exercise, and Monocarboxylate transporter (MCT) 4 expression increased in groups treated with RGP. However, there was no significant change in MCT1. Conclusions: These results suggest that RGP exerts several anti-fatigue properties by lower lactate and improved exercise capacity. Increased MCT4 expression may also affect lactate transport. Thus, this study suggests that the anti-fatigue properties of RGP might be associated with MCT4 activity.

A Case Study on Engineering Experiment Lesson Using on-line pre-Learning for Improvement of Self-regulated Learning Ability (온라인 사전학습을 적용한 공학 실험 수업에서 자기조절학습 능력 개선 사례 연구)

  • Kang, Moon-sang
    • Journal of Engineering Education Research
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    • v.18 no.5
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    • pp.59-66
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    • 2015
  • In the on-line pre-learning which is applied in this study, on line pre-learning, in-class, post-learning are circulated together in the same experiments. The on-line pre-learning has been tried to 136 students in A junior college in Seoul for 3 years. The effects of their self-regulated learning are as follows. First, the self-regulated learning ability has increased by 0.42 point. The point after the self-regulated learning and before it is 3.24 and 3.66 respectively. Second, cognitive regulation, motivational regulation and behavioral regulation have also increased. Out of them, cognitive control has increased the most. Metacognitive strategy is higher than cognitive strategy. In conclusion, the result shows that the on-line pre-learning is helpful to develop the self-regulated learning ability and it is also suitable to teaching-learning method for junior college.

Effect of Feet Cooling and Feet Warming on the Behavioral Temperature Regulation (족부의 냉각과 가온이 행동성 체온조절에 미치는 영향)

  • Jeong, Woon-Seon
    • The Korean Journal of Community Living Science
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    • v.18 no.4
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    • pp.681-686
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    • 2007
  • This study was conducted to investigate the effects of the thermally different states of human feet on temperature regulation in winter season. Five healthy female students of age 20 volunteered as subjects to participate in the study. Physiological responses such as rectal temperature and skin temperatures as well as subjective responses of thermal comfort and thermal sensation were observed. Preferred clothing and preferred temperature were also evaluated in terms of behavioral temperature regulation. The results obtained through the experiment were statistically analyzed using paired t test. Rectal temperature was decreased greater (p<.01) and mean skin temperature was maintained higher (p<.01) in feet wanning than in feet cooling. Results of preferred clothing were coincident with those of general thermal sensation. There was a higher tendency to prefer temperature in feet wanning than feet cooling in the morning. It was concluded that keeping feet skin temperature lower in the early morning and higher in the late evening would be effective in terms of regulating circadian rhythm of core temperature.

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How Background Music Affects Consumer Perception of Waiting Time? -A Mediating Role of Emotions-

  • Park, Jee-Sun;Stoel, Leslie D.
    • Journal of Fashion Business
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    • v.22 no.3
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    • pp.16-29
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    • 2018
  • The present study examines whether consumers' perception of waiting time and their behavioral intentions are influenced by the presence of background music in an online shopping environment. In particular, this study aims to explain the underlying mechanism for the effects of background music on consumers' perceived wait and behavioral intentions toward the online retailer by proposing the mediating role of emotions drawing on the Stimulus-Organism-Response (S-O-R) framework. A lab experiment was employed to test the hypotheses. A total of 102 college students were used for data analyses. Results show that the presence of music has a significant impact on participants' emotions, perceived waiting time, and approach behavior. Moreover, the findings show that pleasure and the perceived waiting time serve as mediators in the relationship between the presence of music and approach behavior. Implications of the model for theory, practice, and further research are discussed.