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http://dx.doi.org/10.13066/kspm.2012.7.1.037

The Effects of Training in Exercise Rehabilitation on Depressive mood, BPSD in Elderly with Alzheimer's Disease  

Cho, Sung-Hyoun (Department of Physical Therapy, Boram Care Hospital)
Kim, Cheol-Yong (Department of Physical Therapy, Ulsan Science College)
Publication Information
Journal of the Korean Society of Physical Medicine / v.7, no.1, 2012 , pp. 37-47 More about this Journal
Abstract
Purpose : The purpose of this study is to examine the effects of training in exercise rehabilitation on depressive emotion, behavioral and psychological symptoms(BPSD) caused by Alzheimer's disease elders. Methods : The subjects of this study were 34 patients with Alzheimer's disease over 65 and assigned randomly into one of two groups, each with 17 people. The experimental group was treated by training in exercise rehabilitation executed 60 minutes, 3 times a week for 8 weeks. The results of the experiment were analyzed using samples t-test along with averages and standard deviations as the statistical methods for data analyses. Results : The results of this study were as follows. First, the experimental group showed statistically significant improvements in the areas of depressive emotion(SGDS) compared to control group. Second, the experimental group showed statistically significant improvements in the severity of behavioral and psychological symptoms and subjective degrees of pain of care givers(NPI-Q) compared to control group. Conclusion : Based on the results of this study, training in exercise rehabilitation have an effect on depressive mood and BPSD in elderly with Alzheimer's disease.
Keywords
Exercise rehabilitation; Depressive mood; Psychological-Behavioral symptoms;
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1 McKhann G, Drachman D, Folstein M et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology. 1984;34(7):939-44.   DOI
2 Morris JC, Storandt M, Miller JP et al. Mild cognitive impairment represents early-stage Alzheimer disease. Arch Neurol. 2001;58(3):397-405.
3 O'Connor PJ, Aenchbacker III LE, Dishman RK. Physical activity and depression in the elderly. J Aging & Physical Activity. 1993;1(1):34-58.   DOI
4 Prince JA, Zetterberg H, Andreasen N et al. APOE epsilom 4 allele is associated with reduced cerebrospinal fluid levels of a beta 42. Neurology. 2004;63(11): 2116-228.
5 Raggi A, Iannaccone S, Marcone A et al. The effects of a comprehensive rehabilitation program of Alzheimer's disease in a hospital setting. Behav Neurol. 2007;18(1):1-6.   DOI
6 Ransford CP. A role for amines in the antidepressant effect of exercise: a review. Med Sci Sports Exerc. 1982; 14(1):1-10.
7 Sadock BJ, Sadock VA. Comprehensive textbook of Psychiatry. 8th ed. New York. Lippincott Williams and Wilkins. 2005:3671-83.
8 Snowden M, Sato K, Roy-Byrne P. Assessment and treatment of nursing home residents with depression or behavioral symptoms associated with dementia: A review of the literature. J Am Geriatr Soc. 2003;51(9):1305-17.   DOI   ScienceOn
9 Tallis R, Fillit HM. Brocklehurst's Textbook of Geriatric Medicine. 6th ed. Churchill & Livingstone. 2003.
10 Teri L, Gibbons LE, McCurry SM et al. Exercise plus behavioral management in patients with Alzheimer disease: A randomized controlled. JAMA. 2003;290(15):2015-22.   DOI   ScienceOn
11 Yesavage J. Differential diagnosis between depression and dementia. Am J Med. 1993;94(5):23-28.
12 Yesavage JA, Brink L, Rose TL et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiat Res. 1983; 17(1):37-49.
13 Williams CL, Tappen RM. Effect of exercise on mood in nursing home residents with Alzheimer's disease. AM J Alzheimer Dis Other Demen. 2007;22(5):389-97.   DOI
14 Williams CL, Tappen RM. Exercise training for depressed older adults with Alzheimer's disease. Aging Ment Health. 2008; 12(1):72-80.   DOI   ScienceOn
15 대한노인정신의학회. 한국형 치매 평가검사. 서울. 학지사. 2003.
16 김상윤. 경도인지장애의 임상소견. 대한치매학회지. 2003;2(2):96-100.
17 김설향. 치매노인을 위한 신체자극 운동프로그램 개발. 한국사회체육학회지, 2005; 25:503-15.
18 김영숙. 회상을 적용한 집단미술치료프로그램이 치매노인의 인지기능, 우울과 삶의 질에 미치는 효 과. 경북대학교 대학원. 박사학위논문. 2004.
19 김혜순, 이여진, 박광희 등. 인지건강증진 프로그램이 노인의 인지기능, 우울 및 삶의 질에 미치는 효과. 한국콘텐츠학회. 2010;10(8):227-39.
20 대한신경정신의학회. 치매-일찍 알고 밝게 살자. 서울. 조선일보사. 2002.
21 대한치매학회. 치매 임상적 접근. 서울. 아카데미아. 2006.
22 박현숙. 치매노인의 인지기능, 일상생활능력 및 평형성에 대한 운동프로그램의 유용성. 서울기술과 학대학교 대학원. 석사학위 논문. 2009.
23 이은희, 이정화. 몬테소리 프로그램이 치매노인의 인지기능, 우울, 대인관계 및 일상생활 수행능력 에 미치는 영향 연구. 한국노인복지학회. 2005; 30:237-61.
24 배재남. DSM-III-R 주요 우울증에 대한 geriatric depression scale의 정확 진단도. 서울대학교 대학원. 석사학위 논문. 1996.
25 보건복지가족부. 치매노인유병률조사. 2008.
26 연병길, 서국희, 류성곤 등. 정상노인 및 노인 치매 환자와 우울증 환자의 삶의 질 비교. 노인정신의학. 1999;3(2):157-64.
27 조맹제, 배재남, 서국희 등. DSM-III-R 주요우울증에 대한 한국어판 Geriatric depression scale(GDS) 의 진단적 타당성 연구. 신경정신의학. 1999;38 (1):48-63.
28 Alexopoulos GS. New concepts for prevention and treatment of late-life depression. Am J Psychiatry. 2001;158(6):835.   DOI   ScienceOn
29 Arkin SM. Elder Rehab: A student- supervised exercise program for Alzheimer's patients. Gerontologist. 1999;39(6):729-35.   DOI
30 Bartels SJ, Clark RE, Peacock WJ et al. Medicare and medicaid costs for schizophrenia patients by age cohort compared with costs for depression, dementia and medically ill patients. Am J Geriat Psychiat. 2003;11(6):648-57.   DOI
31 Blumenthal JA, Babyak MA, Moore KA et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159 (19):2349-56.
32 Bondareff W. Neuropathology of psychotic symptoms in Alzheimer's disease. Int Psychogeriatr. 1996;8 (3):233-7.   DOI   ScienceOn
33 Carpenter B, Ruckdeschel K, Ruckdeschel, H et al. R-E-M psychotherapy: A manualized approach for long-term care residents with depression and dementia. Clin Gerontol. 2002;25:25-49.
34 Fiatarone MA, O''Neill EF, Ryan ND et al. Exercise training and nutritional supplementation for physical frailty in very elderly people. New Engl J Med. 1994;330(25):1769-75.   DOI   ScienceOn
35 Cedazo-Minguez A, Popescu O., Blanco-Millian JM et al. Apolipoprotein E and beta-amyloid regulation of glycogen synthase kinase-3beta. J Neurochem. 2003;87(5):1152-64.   DOI   ScienceOn
36 Chung JA, Cummings JL. Neurobehavioral & neuropsychiatric symptoms in Alzheimer's disease: Characteristrics and treatment. Neurol Clin. 2000;18(4):829-46.   DOI
37 Corey-Bloom J. Alzheimer's disease. American academy of neurology. Continuum Dementia. Pliladelphia. PA. 2004;10(1): 29-47.
38 Forsell Y, Jorm AF, Winblad B. Outcome of Depression in Demented and Non-demented Elderly: Observations from a three-year follow-up in a community- based study. Int J Geriatr Psych. 1994;9(1):5-10.   DOI   ScienceOn
39 Frisoni GB, Padovani A, Wahlund LO. The predementia diagnosis of Alzheimer disease. Alz Dis Assoc Dis. 2004;18(2):51-53.   DOI   ScienceOn
40 Hui JS, Wilson RS, Bennett DA et al. Rate of cognitive decline and mortality in Alzheimer's disease. Neurology. 2003;61(10):1356-61.   DOI   ScienceOn
41 Jhoo JH, Kim KW, Huh Y et al. Prevalence of dementia and its subtypes in an elderly urban Korean population: results from the Korean Longitudinal Study on Health and Aging(KLoSHA). Dement Geriatr Cogn. 2008;26(3):270-76.   DOI   ScienceOn
42 Kaufer DI, Cummings JL, Ketchel P et al. Validation of the NPI-Q, a Brief Clinical Form of the Neuropsychiatric Inventory. J Neuropsych Clin N. 2000;12(2):233-9.   DOI
43 Larson EB, Wang L, Brown JD et al. Exercise is associated with reduced risk for incident dementia among persons 65years of ages or order. Ann Intern Med. 2006;144(2):73-81.   DOI   ScienceOn
44 Kawas C, Gray S, Brookmeyer R et al. Age-specific incidence rates of Alzheimer's disease: The Baltimore Longi- tudinal Study of Aging. Neurology. 2000;54(11):2072-77.   DOI   ScienceOn
45 Knopman DS, DeKosky ST, Cummings J et al. Practice parameter: Diagnosis of Demetia. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56(9):1143-53.   DOI   ScienceOn
46 Knopman D, Donohue JA, Guttreman EM. Patterns of care in the early stages of Alzheimer's disease: Impairments to timely diagnosis. J Am Geriatr Soc. 2000;48(3):300-4.   DOI   ScienceOn
47 Labbe EE, Welsh MC, Delaney D. Effects of consistent aerobic exercise on the psychological functioning of women. Percept Mot Skills. 1988; 67(3):919-25.   DOI   ScienceOn
48 Linda E, Carlson BB, Sherwin HM. Relat- ionships between Dehydroepiandrosterone sulfate(DHEAs) and cortisol(CRT) plasma levels and everyday memory in Alzheimer's disease patients compared to healthy controls. Horm Behav. 1999;35(3): 254-63.   DOI   ScienceOn
49 Low LF, Brodaty H, Draper B. A Study of premorbid personality and behavioral and psychological symptoms of dementia in nursing home residents. Int J Geriatr Psych. 2002;17(8): 779-83.   DOI   ScienceOn
50 Mather AS, Rodriguez C, Guthrie MF et al. Effects of exercise on depressive symptoms in older adults with poorly responsive depressive disorder. Brit J Psychiat. 2002;180(5):411-5.   DOI   ScienceOn
51 Mathews RM, Clair AA, Kosloski K. Keeping the beat: Use of rhythmic during exercise activities for the elderly with dementia. Am J Alzheimers Dis Other Demens. 2001;16(6):377-80.   DOI