• Journal of Pharmacopuncture
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• v.9 no.1
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• pp.121-126
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• 2006

Objective : The purpose of the study was to observe local reactions of BV and BVP skin test, and to compare those between BV and BVP. Methods : We performed BV or BVP Skin test to 42 patients, and then we measured wheal and erytherma on skin test area by digital caliper after 15 minutes. Results : 1. In BV Skin test, the mean size of wheals was $l0.l0{\pm}0.78mm$ and the mean size of erythermas was $29.85{\pm}6.23mm$. 2. In BVP Skin test, the mean size of wheals was $7.05{\pm}3.20mm$ and the mean size of erythermas was $19.58{\pm}7.62mm$. 3. The local reactions of BVP Skin test decreased significantly(P<0.01) than those of BV skin test.

• Journal of Pharmacopuncture
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• v.9 no.3 s.21
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• pp.79-88
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• 2006

Objectives : This systematic review summarizes the existing evidence on anti-tumor herbal acupuncture in South Korea. Methods : Literature searches were conducted in four databases. All studies of anti-tumor herbal acupuncture which has been published in South Korea until May, 2006 were included. Data were extracted according to pre-defined criteria by two independent reviewers. Results : We found 73 papers related to anti-tumor herbal acupuncture in South Korea. Seventy of seventy-three papers are trial research and only three papers are clinical research. Herb materials which were used in those papers are Bee-venom, Wild-ginseng, Ginseng, Houttuynia cordata Thunb, Lonicerae Flos, Carthami Tinctorii Juglans sinensis, Euphorbiae Radix, Ecliptae Herba, Crotonis Semen, Juglans sinensis, Armeniaceae Amarum, so on. From those papers, Anti-tumor herbal acupunctures are effective to tumor cell line and tumor in vivo. Clinical research papers reported that Anti-tumor herbal acupunctures are useful to improve cancer related symptoms and quality of life(QOL) of cancer patients. Conclusions : From the above results, we make sure of that anti-tumor herbal acupuncture is useful therapeutics for cancer patients. If we conceive complex-herb materials and carry out more advanced research, Anti-tumor Herbal Acupuncture is one of those major therapeutics to improve clinical symptoms and quality of life(QOL) of cancer patients.

• Journal of Acupuncture Research
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• v.29 no.1
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• pp.47-59
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• 2012

목적 : 이 연구는 봉독이 사람의 난소암 세포인 SKOV3와 PA-1에서 death receptor의 발현을 높여 세포자멸사를 촉진함으로써 암세포의 성장을 억제하는지 밝히고자 하였다. 방법 : 난소암의 세포자멸사의 관찰에는 DAPI, TUNEL staining assay를 시행하였으며, 세포자멸사 조절 단백질의 변동 관찰에는 western blot analysis를 시행하였고, 난소암 세포에서 death receptor의 변화를 관찰하기 위해 RT-PCR analysis를 시행하였다. 결과 : 1. DAPI, TUNEL staining assay 결과, 봉독은 투여량에 따라 세포자멸사의 유도를 통해 SKOV3와 PA-1 난소암세포의 증식을 억제하였고, 세포자멸사와 동반하여 DR4와 DR6의 발현이 두 암세포 모두에서 증가하였고, DR3의 출현은 PA-1 세포에서 증가하였다. 2. Death Receptor의 발현 증가에 따라 caspase-3, 8, 9 and Bax를 포함하는 세포자멸사 촉진 단백질의 발현이 동반하여 상승하였고 JAK2, STAT3의 인산화와 Bcl-2의 발현은 억제되었다. 3. siRNA 처리 시 봉독에 의한 DR3, DR4, DR6 발현증가와 STAT3의 활성억제가 역전되었다. 결론 : 이러한 결과는 봉독이 난소암 세포에서 DR3, DR4, DR6의 증가와 JAK2/STAT3 pathway의 억제를 통하여 세포자멸사를 유발한다는 것을 시사하며, 난소암의 예방과 치료에 효과적으로 활용될 수 있을 것으로 기대된다.

• Journal of Acupuncture Research
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• v.35 no.2
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• pp.52-60
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• 2018

Background: This was a retrospective review of published articles reporting acupuncture and moxibustion treatment of peroneal nerve palsy. Methods: On-line database searches were carried out using; Cochrane Library, Pubmed, CNKI, NDSL and OASIS to find articles reporting acupuncture and moxibustion treatment for peroneal nerve palsy. Duplicate articles and studies that were not relevant to the topic were excluded, along with review articles and commentaries. Results: 20 studies were selected, 18 clinical case studies (47 patients) and 2 randomized controlled trials (154 patients). Intervention treatments included acupuncture, moxibustion, bee-venom (BV), pharmacopuncture, electroacupuncture and acupotomy. Surprisingly, although peroneal nerve palsy is not a very rare disease, only 2 studies out of 20 carried out a randomized controlled trial. Conclusion: Although studies to date report the efficacy of acupuncture and moxibustion treatment in peroneal nerve palsy patients, the absence of objective evaluation and the absence in the reporting of side-effects remains an issue.

• Journal of Korean Medicine Rehabilitation
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• v.25 no.3
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• pp.27-36
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• 2015

Objectives The aim of this review is to analyze research trends on the Korean medical treatment and study of fracture. Methods We searched 38 studies related treatment of fracture via Korean medicine web databases. We classified these studies by three types (experimental reports, case reports and retrospective reports) and researched how to treat the patient of fracture. Results 38 studies were published since 1993 and published every year since 2004 to 2013. There were 8 experimental reports, 20 case reports and 10 retrospective reports. Most of these studies were effective to treat of fracture. Bee venom treatment and Hua-Tuo-Jia-Ji-Xue acupuncture treatment were more effective than general treatment. Conclusions These results suggest that Korean medicine is effective treatment to fracture and we need continuously agonize and research more effective therapy method.

• Journal of Korean Medicine Rehabilitation
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• v.23 no.4
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• pp.261-268
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• 2013

This study was performed to report the case of Korean medical treatment for the Patulous Eustachian tube patient with headache. The patient was treated by acupuncture, herbal medicine, bee venom injection, needle-embedding therapy, chuna therapy, release of cranial base and sacro-occipital therapy. Korean medical treatment was administered during 3 weeks. The improvement of clinical symptoms was evaluated by VAS (visual analogue scale) and SF-36 (36-Item Short Form Healthy Survey Instrument). After treatment, most symptoms decreased, headache VAS score changed 10 to 6 and tinnitus VAS score changed 10 to 5. Also, most SF-36 scores increased. Our study suggested that Korean medical treatments are effective in the patient with Patulous Eustachian tube. And further studies are required to identify underlying mechanism of treatment.

• Journal of Korean Medicine Rehabilitation
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• v.26 no.4
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• pp.127-136
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• 2016

The purpose of this study is to report a clinical progress of fibromyalgia syndrom patient treated by Korean Medicine treatment. The patient was treated with acupuncture, acupotomy, pharmacopuncture (Bee venom, Hwangryun, Hominis Placental), herbal medicine, moxibustion, cupping treatment. We measured Visual Analogue Scale (VAS), American College of Rheumatology Preliminary Diagnostic Criteria (ACR, 2010), Fibromyalgia Impact Qustionnaire (FIQ), and observed the change in body temperature using Digital Infrared Thermal Imaging (DITI). After Korean Medicine treatment, pain was controlled and VAS, ACR, FIQ were decreased. The result showed that Korean Medicine treatment is effective in fibromyalgia syndrome.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.9 no.2
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• pp.21-33
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• 2014

Objectives : This study was to report the improvement of the patient with multiple sclerosis treated by Korean Medical treatment. Methods : The patient diagnosed as multiple sclerosis treated by acupuncture, bee venom pharmacupuncture, chuna manual therapy, and herbal medicine. To evaluate the effects of korean medicine, we used manual muscle test(MMT), the standard for assessment of the effect of stroke treatment, functional system(FS), visual analog scale(VAS). Results : 1. The patient's pain and optic dysfunction were reduced by the above therapy. 2. There was no change in manual muscle test(MMT), but there was mild improvement in finger joints function in the standard for assessment of the effect of stroke treatment. 3. In functional system(FS) scale, there was enhancement in optic function within a range. And there was improvement in expanded disability statue scale(EDSS) from 4.0 to 3.0. 4. In visual analog scale(VAS), there was considerable improvement from 9 to 6. Conclusions : The korean medical treatment was reduced pain and optic dysfunction.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.2
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• pp.55-65
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• 2019

Objectives : The aim of this study was to report the improvements in pain that a woman experienced after receiving Korean medicine treatments for the pain associated with core decompression surgery due to avascular necrosis (AVN) of both femur heads. Methods : The patient was diagnosed as having AVN in both femur heads and underwent core decompression surgery. After operation, she had pain on her right inguinal region and her range of motion (ROM) was restricted. She was treated with Korean medicine including, herbal medicine, acupuncture, Chuna Manual Therapy and bee venom acupuncture (BV). This study was measured by using the Visual Analogue Scale (VAS) and the ROM scale. Results : After conservative treatment, the patient's pain was reduced and ROM was increased. Daily living quality had improved. Conclusions : In this case, Korean conservative medicine therapy with Chuna Manual Therapy had a positive effect on the symptoms after core decompression surgery due to avascular necrosis of the femur head.

• Journal of Acupuncture Research
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• v.32 no.3
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• pp.229-236
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• 2015

Objectives : The purpose of this study is to report the clinical effect of Korean medical treatment on a spinal cord tumor. Methods : We treated a patient who was diagnosed with a spinal cord tumor. We used acupuncture, bee venom pharmacopuncture, herbal medicine, moxibustion and physical therapy; the patient was evaluated using the visual analogue scale(VAS) and given an International Standards for Neurological Classification of Spinal Cord Injury(ISNCSCI) score. Results : VAS decreased and ISNCSCI score increased meaningfully. Conclusions : According to these results, this report possibly suggests that Korean medical treatment could be a helpful choice for treating a spinal cord tumor.