• 핵의학기술
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• 제18권1호
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• pp.62-68
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• 2014

치료 후 I-131 SPECT/CT는 잔류 갑상선 위치확인 및 전이유무를 판단하기 위하여 시행된다. 잔류 갑상선에 집적이 심한 경우 영상은 ringing artifact에 의하여 왜곡된다. 본 연구는 ringing artifact를 제거하고 영상의 질을 향상시키기 위한 적절한 post-filter의 적용에 대하여 제시하고자 한다. 본 실험은 hollow sphere와 아크릴통으로 구성된 phantom을 사용하여 SPECT/CT Discovery 670 (GE Healthcare, USA) 장비로 수행하였다. I-131용액을 hollow sphere에 184, 46, 9.2, 2.3 MBq/cc, 아크릴통에 46 kBq/cc을 각각 주입하였고 sphere 대 background의 비를 4000:1, 1000:1, 200:1, 50:1로 설정하였다. 데이터는 다음과 같은 조건으로 획득하였다(HEGP collimator 사용, Attenuation collection 적용, scan time 40 secs/frame, step angle 6도, scan mode non circular, evolution 적용과 미적용). 획득된 데이터는 OSEM (iteration 2, subset 10) 방식으로 재구성하였다. Post-filer의 사용에 따른 이미지의 변화를 보기 위해 3가지의 다른 post-filer들이 사용되었다(butterworth filter cut-off: 0.38, 0.43, 0.48, 0.53, 0.58, hanning filter cut-off: 0.8, 0.85, 0.9, 0.95, 1, gaussian FWHM: 3, 3.4, 4, 4.5, 5). 각각의 데이터는 MRIcro를 사용하여 contrast ratio, background variability를 분석하였고 e.soft ROI tool을 사용하여 FWHM값을 구하였다. Evolution을 적용한 경우, 모든 결과에서 contrast ratio값이 높게 나타났다. Evolution을 적용하지 않은 경우 star artifact 등 왜곡이 발생하였고 영상의 질이 현저히 낮아짐을 확인할 수 있었다. 4000:1, 1000:1, 200:1의 경우, butterworth filter 사용 시 ringing artifact가 발생하였으며 cut-off값이 커질수록 artifact가 감소하였다. Hanning filter를 사용한 경우 ringing artifact는 발생하지 않았다. Contrast ratio와 FWHM값이 butterworth filter나 hanning filter 적용 시 우수하였다. Gaussian filter경우 contrast ratio와 FWHM값에서 저조한 결과를 얻을 수 있었다. 50:1의 경우, 모든 경우에서 ringing artifact가 발생하지 않았다. Butterworth filter를 적용한 경우 가장 높은 contrast ratio와 가장 우수한 FWHM값을 나타내었다. 본 논문을 통하여 I-131 SPECT에서 ringing artifact가 발생 할 경우(thyroid remnant를 포함) hanning filter를 사용하여 영상을 재구성하고, ringing artifact가 발생하지 않을(remnant thyroid를 포함하지 않음) 경우 butterworth filter를 사용하여 재구성하는 것이 바람직하다는 사실을 알 수 있었다.

• 스트레스연구
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• 제26권4호
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• pp.305-311
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• 2018

화병은 뚜렷한 스트레스 사건과 관련되어 가슴의 답답함, 열감, 치밀어 오름, 억울하고 분한 감정 등이 나타나는 증후군이다. 본 논문에서는 화병에 대한 황련해독탕의 임상시험 결과를 교감신경의 활성도를 반영한다고 알려져 있는 심박변이도의 저주파(0.04~0.15 Hz) 영역 값을 중심으로 분석하여 다음과 같은 결과를 얻었다. 첫째, 황련해독탕 시험군에서 초기 심박변이도 저주파 값이 클수록 불면 증상의 개선 정도가 작게 나타났다. 둘째, 위약과 비교했을 때, 황련해독탕은 복용 7일 후 심박변이도 저주파 값을 유의하게 감소시켰다. 셋째, 화병 증상 중 가슴이 답답함, 치밀어 오름, 분노가 심박변이도 저주파 값과 유의미한 상관성이 있었다. 이를 바탕으로 심박변이도는 화병 환자를 평가할 때 유용할 것이라고 기대된다.

• 대한한방내과학회지
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• 제19권2호
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• pp.7-16
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• 1998

Background and Purpose The increasing evidence for neurally mediated cardiac damage and sudden death has focused attention on the central autonomic control of cardiac function. Power spectral analysis of heart rate variability(HRV) can detect autonomic consequences of stroke. We performed power spectral analysis of heart rate variability from 24-hour holter recording to identify cerebral hemispheric lateralization and gender effect in cardiac autonomic control. Methods Data were obtained from 24-hour holter recordings in 30 consecutive patients with hemispheric brain infarction in the subacute phase. We analysed the time domain and frequency domain measures of HRV and ST segment by hemispheric lateralization and Gender. Results ST segment was depressed in women compared with man. There was no statistically significant differences between right and left hemisphere stroke patients in any standard index of HRV and ST segment changes. Conclusions These data are partial consistent with evidence from the recent literature that two cerebral hemispheres and gender have a differential influence on the nature and severity of cardiac dysfunction. We think the prospective and definite study was necessary.

• Clinics in Orthopedic Surgery
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• 제10권4호
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• pp.462-467
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• 2018

Background: Significant discrepancy exists between anatomical plate designs and the anatomy of the native distal radius, which may be attributable to considerable morphometric variations in the volar aspect of the distal radius. We aimed to evaluate the degree of variability in the morphometry of the distal radius and identify factors associated with this variability. Methods: We measured the volar surface angle (VSA) of the intermediate and lateral columns and the volar surface width (VSW) in the distal radius from three-dimensional computed tomography scans acquired from 81 cadaveric forearms. These morphometric parameters were compared between the lateral and intermediate columns, between males and females, and between Koreans and Caucasians. Caucasian morphometric data were obtained and pooled from the previous studies. The coefficient of variation was used to assess the variability of the parameters and Cohen's d to estimate the effect size of the difference between groups. Results: The average VSA of the lateral column was $22^{\circ}{\pm}6^{\circ}$, and that of the intermediate column was $29^{\circ}{\pm}8^{\circ}$ in Koreans (p < 0.001). The variability was high for both VSAs. The VSA of the intermediate column was significantly larger in males than in females (p < 0.001) and in Caucasians than in Koreans (p < 0.001). The average VSW of distal radius was $30{\pm}3mm$ at the watershed line, and it became narrower proximally. The VSW was significantly larger in males than in females (p < 0.001) and in Koreans than in Caucasians (p < 0.001). The effect sizes of the difference for the VSA and VSW between sexes, races and columns were medium to large. Conclusions: Considerable variability exists in the morphometry of the volar distal radius, with sex, race, and column as contributing factors. These results suggest that surgeons should carefully choose an anatomical volar locking plate with appropriate angulation characteristics for each patient to achieve patient-specific alignment of the distal radius.

• 한방안이비인후피부과학회지
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• 제24권3호
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• pp.65-73
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• 2011

Background : There are findings indicating that the autonomic nervous system (ANS) is affected negatively in atopic dermatitis (AD). Heart rate variability (HRV) is a tool to examine ANS. But, studies investigation the relationship between AD and HRV is rare. Objective : The aim of this study was to investigate the correlation between atopic dermatitis severity and HRV and to find out the role of ANS in AD. Methods : Retrospective chart review was performed. The Severity Scoring Atopic Dermatitis (SCORAD) index and HRV parameter was investigated and analyzed. Results : There were 55 patients (25males and 30 females) who met the criteria. Objective SCORAD had significant positive correlation with HRT and Subjective SCORAD had significant negative correlation with SDNN, TP and VLF. Intensity item of SCORAD index had negative correlation with most HRV parameters, but TP, LF and LF/HF ratio had significant positive correlation with dryness. Conclusion : This study supports the concept that atopic dermatitis is a stress-responsive disorder and involves autonomic nervous system dysfunction.

• Ocean and Polar Research
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• 제41권3호
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• pp.121-133
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• 2019

Natural variability associated with a variety of large-scale climate modes causes regional differences in sea level rise (SLR), which is particularly remarkable in the Pacific Ocean. Because the superposition of the natural variability and the background anthropogenic trend in sea level can potentially threaten to inundate low-lying and heavily populated coastal regions, it is important to quantify sea level variability associated with internal climate variability and understand their interaction when projecting future SLR impacts. This study seeks to identify the dominant modes of sea level variability in the tropical Pacific and quantify how these modes contribute to regional sea level changes, particularly on the two strong El $Ni{\tilde{n}}o$ events that occurred in the winter of 1997/1998 and 2015/2016. To do so, an adaptive data analysis approach, Ensemble Empirical Mode Decomposition (EEMD), was undertaken with regard to two datasets of altimetry-based and in situ-based steric sea levels. Using this EEMD analysis, we identified distinct internal modes associated with El $Ni{\tilde{n}}o$-Southern Oscillation (ENSO) varying from 1.5 to 7 years and low-frequency variability with a period of ~12 years that were clearly distinct from the secular trend. The ENSO-scale frequencies strongly impact on an east-west dipole of sea levels across the tropical Pacific, while the low-frequency (i.e., decadal) mode is predominant in the North Pacific with a horseshoe shape connecting tropical and extratropical sea levels. Of particular interest is that the low-frequency mode resulted in different responses in regional SLR to ENSO events. The low-frequency mode contributed to a sharp increase (decrease) of sea level in the eastern (western) tropical Pacific in the 2015/2016 El $Ni{\tilde{n}}o$ but made a negative contribution to the sea level signals in the 1997/1998 El $Ni{\tilde{n}}o$. This indicates that the SLR signals of the ENSO can be amplified or depressed at times of transition in the low-frequency mode in the tropical Pacific.

• 한국대기환경학회지
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• 제17권3호
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• pp.277-288
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• 2001

Continuous atmospheric CO$_2$measurements measured during the 1 year(1998.8∼1999.8) at Korea Global Atmosphere Watch Observatory (KGAWO) in Anmyeon-do are analyzed by the selecting method which is recommended by WDCGG to get background CO$_2$. This method can reject data based on two criteria: the instability of CO$_2$ concentration within 1 hour from hourly standard deviation (hourly variability$\leq$ 0.6 ppm first selection) and the large changes in the CO$_2$ concentration from one hour to the nex(∼$\leq$0.3 ppm, second selection). We could obtain hourly background CO$_2$ of 37% in first selection and 20% in second selection during the l year. That are a little less than those of Ryori station in Japan. especially, the cases of background CO$_2$ which is selected were few during the summer. That is caused by affection of vegetation and anthropogenic source. After the selecting methods are applied, the cases which is selected for easterly wind decrease remarkably according to the analysis of wind direction about continuous CO$_2$ .That was affected by anthropogenic source from the east area.

• 대한한방내과학회지
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• 제44권1호
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• pp.66-76
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• 2023

Background: The aim of this study is to investigate the use of heart rate variability on a stroke patient with autonomic dysfunction and the effectiveness of Bunshimgi-eum. Case report: The patient showed autonomic dysfunction, including chest discomfort, 煩燥 (sweating, anxiety, insomnia, nausea, lightheadedness), and abdomen discomfort (dyspepsia, heartburn) after ischemic stroke. She was treated with a herbal medicine (Bunshimgi-eum) through complex Korean medicine treatment. The effect was evaluated using heart rate variability (HRV), Mini-Mental State Examination-DS (MMSE-DS), mean pulse rate, and subjective percentage of symptoms. After treatment, the HRV score, MMSE-DS score, and subjective percentage of symptoms improved, and the pulse rate decreased from the upper boundary value. Discussion: The results suggest that HRV may be useful in evaluating stroke patients with autonomic dysfunction and that Bunshimgi-eum is suitable for treatment.

• 한국지구과학회지
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• 제40권3호
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• pp.240-258
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• 2019

태풍, 집중호우, 대설은 매년 우리나라에서 치명적인 손실을 초래한다. 따라서 정기적인 관측을 통하여 이러한 현상의 발생 가능성을 미리 알 수 있다면, 사회적으로 큰 유익을 제공할 수 있을 것이다. 우리나라는 삼면이 바다로 둘러싸여 있고, 해수면온도가 태풍, 집중호우, 대설 발달에 직 간접적으로 영향을 미치므로, 이 논문에서는 위험기상과 관련하여 나타나는 해수면온도 변동성의 특성을 조사하였다. 우리나라에서 발생하는 집중호우는 서울경기 부근 및 서해안을 중심으로, 그리고 남해안을 중심으로 분포하였다. 대설은 주로 동해안지역(이하 영동 대설)과 남서부 지역(호남형 대설)에서 발생하였다. 위험기상 종류 및 주요 발생지역에 따라 해수면온도 변동성이 조금씩 다르게 나타났으며, 집중호우 발생 시에 진도-제주도-이어도-중국 상하이 방향으로 이어지는 해역에서 해수면온도 변동성이 크게 나타났다. 대설 발생 시, 대설형태와 상관없이, 제주도 남쪽 해상에서 해수면온도 변동성이 작은 영역이 관측되었으며, $130^{\circ}E$, $39^{\circ}N$ 부근 동해상에서 강한 해수면온도 변동성이 나타났다. 해수면온도 변동성이 큰 지역은, 대기-해양 상호작용 메커니즘을 연구하는 기초자료로 사용될 수 있을 뿐만 아니라, 배경대기 에어로졸 관측영역 결정에도 활용될 것이다.

• International Journal of Contents
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• 제8권4호
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• pp.95-102
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• 2012

In this paper, we present a technique to extract the title areas from book cover images. A typical book cover image may contain text, pictures, diagrams as well as complex and irregular background. In addition, the high variability of character features such as thickness, font, position, background and tilt of the text also makes the text extraction task more complicated. Therefore, we propose a two steps efficient method that uses Histogram of Oriented Gradients and color information to find the title areas. Firstly, text localization is carried out to find the title candidates. Finally, refinement process is performed to find the sufficient components of title areas. To obtain the best result, we also use other constraints about the size, ratio between the length and width of the title. We achieve encouraging results of extracted title regions from book cover images which prove the advantages and efficiency of the proposed method.