The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지
DOI QR코드

DOI QR Code

A Case Report on the Use of Heart Rate Variability and the Treatment Effect of Bunshimgi-eum on Autonomic Dysfunction After Cerebral Infarction

뇌경색 후 발생한 자율신경 장애에 대해 심박변이도로 살펴본 분심기음의 효과 증례보고 1례

  • Jun-seok Kim (Dept. of Korean Internal Medicine of Cardiovascular and Neurologic Diseases, College of Korean Medicine, Daegu Haany University) ;
  • Ji-hyeon Kang (Dept. of Korean Internal Medicine of Cardiovascular and Neurologic Diseases, College of Korean Medicine, Daegu Haany University) ;
  • Seo-hyun Kim (Dept. of Korean Internal Medicine of Cardiovascular and Neurologic Diseases, College of Korean Medicine, Daegu Haany University) ;
  • Chae-eun Kim (Dept. of Korean Internal Medicine of Cardiovascular and Neurologic Diseases, College of Korean Medicine, Daegu Haany University) ;
  • Na-yeon Kim (Dept. of Korean Internal Medicine of Hepatology, College of Korean Medicine, Daegu Haany University) ;
  • Woo-seok Jang (Dept. of Korean Internal Medicine of Cardiovascular and Neurologic Diseases, College of Korean Medicine, Daegu Haany University)
  • 김준석 (대구한의대학교 부속 대구한방병원 심계내과학교실) ;
  • 강지현 (대구한의대학교 부속 대구한방병원 심계내과학교실) ;
  • 김서현 (대구한의대학교 부속 대구한방병원 심계내과학교실) ;
  • 김채은 (대구한의대학교 부속 대구한방병원 심계내과학교실) ;
  • 김나연 (대구한의대학교 부속 대구한방병원 간계내과학교실) ;
  • 장우석 (대구한의대학교 부속 대구한방병원 심계내과학교실)
  • Received : 2023.02.24
  • Accepted : 2023.03.31
  • Published : 2023.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

Background: The aim of this study is to investigate the use of heart rate variability on a stroke patient with autonomic dysfunction and the effectiveness of Bunshimgi-eum. Case report: The patient showed autonomic dysfunction, including chest discomfort, 煩燥 (sweating, anxiety, insomnia, nausea, lightheadedness), and abdomen discomfort (dyspepsia, heartburn) after ischemic stroke. She was treated with a herbal medicine (Bunshimgi-eum) through complex Korean medicine treatment. The effect was evaluated using heart rate variability (HRV), Mini-Mental State Examination-DS (MMSE-DS), mean pulse rate, and subjective percentage of symptoms. After treatment, the HRV score, MMSE-DS score, and subjective percentage of symptoms improved, and the pulse rate decreased from the upper boundary value. Discussion: The results suggest that HRV may be useful in evaluating stroke patients with autonomic dysfunction and that Bunshimgi-eum is suitable for treatment.

Keywords

References

  1. Chidambaram H, Korhai G, Prasanna KS, Chitrambalam P. Assessment of Autonomic Dysfunction in Acute Stroke Patients at a Tertiary Care Hospital. JCDR 2017;11(2):28-31. https://doi.org/10.7860/JCDR/2017/24740.9431
  2. Agnieszka Z, Jerzy S. Methods of evaluation of autonomic nervous system function. AMS 2010;6(1):11-8.
  3. Anne MD, Greg F. Effects of Stroke on the Autonomic Nervous System. Compr Physiol 2015;5(3):1241-63.
  4. Jeong HJ, Park KJ. Clinical Applications of Heart Rate Variability in Neurological Disorders. J Korean Neurol Assoc 2017;35(1):1-7. https://doi.org/10.17340/jkna.2017.1.1
  5. Alvares GA, Quintana DS, Hickie IB, Guastella AJ. Autonomic nervous system dysfunction in psychiatric disorders and the impact of psychotropic medications: a systematic review and meta-analysis. J Psychiatry Neurosci 2016;41(2):89-104. https://doi.org/10.1503/jpn.140217
  6. Kim YW, Park CI, Song WW, Jang JH. Autonomic Nervous Function Analysis of Geriatric Stroke Patients Using 24-hour Heart Rate Variability. Korean J Clin Geri 2015;6(2):236-42.
  7. Won WY, Lee CU. Pharmacological treatment of psychiatric disorders of the elderly. J Korean Med Assoc 2010;53(11):972-83. https://doi.org/10.5124/jkma.2010.53.11.972
  8. Xhyheri B, Manfrini O, Mazzolini M, Pizzi C, Bugiardini R. Heart Rate Variability Today. Progress in Cardiovascular Diseases 2012;55(3):321-31. https://doi.org/10.1016/j.pcad.2012.09.001
  9. Han JW, Kim TH, Jhoo JH, Park JH, Kim JL, Ryu SH, et al. A Normative Study of the Mini-Mental State Examination for Dementia Screening (MMSE-DS) and Its Short form (SMMSE-DS) in the Korean Elderly. Journal of Korean Geriatric Psychiatry 2010;14(1):27-37.
  10. Zhao M, Guan L, Wang Y. The Association of Autonomic Nervous System Function With Ischemic Stroke, and Treatment Strategies. Front Neurol 2020;10:1-14. https://doi.org/10.3389/fneur.2019.01411
  11. Kim HJ, Kim BK, Kim WI. Comparative Study of Acute Dyspepsia, Functional Dyspepsia, Organic Dyspepsia by HRV(Heart Rate Variability). J of Orienta Neuropsychiatry 2010;21(2):75-85.
  12. Korpelainen JT, Sotaniemi KA, Huikuri HV, Myllyla VV. Abnormal Heart Rate Variability as a Manifestation of Autonomic Dysfunction in Hemispheric Brain Infarction. Stroke 1996;27(11):2059-63. https://doi.org/10.1161/01.STR.27.11.2059
  13. Kim SH. Review on Current Status of Use and Measurement Condition of Heart Rate Variability in Clinical Study of Korean Medicine. The Journal of Korean Acupuncture & Moxibustion Medicine Society 2012;29(5):127-37.
  14. Choi SO, Park SY, Jeong HJ, Jang SY, Ahn SY, Kim KM, et al. Clinical Study on Relationship betwen Patern Identifcations and Heart Rate Variabilty. Korean J Oriental Physiology & Pathology 2013;27(3):318-26.
  15. Lee SH, Kim EJ, Park YC, Koh YJ, Nam DW. Effect of Acupuncture Stimulation on Heart Rate Variability in Stroke Patients. The Journal of Korean Acupuncture & Moxibustion Medicine Society 2006;23(1):135-43.
  16. Lee IW, Shin AS, Kim NH, Kim HM, Shim SR, Kim MK, et al. Clinical Study of Characteristics of Heart Rate Variability in Stroke Patients. The Korean Journal of Joongpoong 2010;11(1):1-8.
  17. Yoon SK, Kwon SW, Seo YR, Park JY, Im JW, Park JY, et al. The Effects of LI4, TE3, TE5 and LI11 Moxibustion on Radial Artery Blood Flow and Heart Rate Variability in Stoke Patients with Hemiplegia. J Korean Oriental Med 2011;32(5):50-65.
  18. Lee JH. Essential Formulae in Oriental Medicine with Illustrations(圖說漢方診療要方). Wonju: Uibang Publishing Company; 2007, p. 377-9.
  19. Kim RS, Lee CH, Lee JM, Cho JH, Jang JB, Lee KS. Neuroprotective Effects of Bunsimgieum. The Journal of Oriental Obstetrics & Gynecology 2009;22(2):119-31.
  20. Lim JW, Jung IC, Lee SR. The Efects of BunSimGiEumGami-Bang(Fenxinqiyinjiameifa ng)on Serotonin of P815 cell. J of Oriental Neuropsychiatry 2011;22(2):147-62.
  21. Jeon YY, Park CG, Park CS, Lee SY, Yoon HD, Shin WC. An Experimental Study of Effect on ECV 304 Cells, Platelet Rich Plasma and Rats treated with L-NAME by Boonsimgieum extract. Korean J Oriental Int Med 2005;26(1):182-98.
  22. Bang JK. The study on the Paeoniae Radix Alba's efficacy in Sanghanron(傷寒論) prescription. J Oriental Medical Classics 2010;23(1):47-58.
  23. Kim IR, Kim HC, Park SJ, Park JH, Seo BI, Seo YB, et al. Bonchohak. Seoul: Yeongnimsa; 2004, p. 231, 397, 458, 646.
  24. Park EK, Shim ES, Jung HS, Sohn NW, Sohn YJ. Effects of Chongmyung-tang, Polygalae Radix and Acori Graminei Rhizoma on Aβ Toxicity and Memory Dysfunction in Mice. Korean J Orient Int Med 2008;29(3):608-20.
  25. Meridians & Acupoints Compilation Committee of Korean medical Colleges. 7th rev. Details of Meridians & Acupoints(Volume 1) A guidebook for college students. Daejeon: JongRyeoNaMu Publishing Co.; 2016, p. 24, 579, 615, 616.
  26. Hwang MS. Study on the Treatment Mechanism of Back-Shu Points for Organ Dysfunction. Korean J Acupunct 2016;33(3):95-101. https://doi.org/10.14406/acu.2016.019