• Journal of Haehwa Medicine
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• v.22 no.2
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• pp.155-162
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• 2014

Objective : The purpose of this study was to investigate the effects of acupuncture treatment on frequently adopted acupuncture point and self exercise therapy for lumbar sprain patient Methods : For this study, a retrospective chart review was conducted. Data are derived from lumbar sprain patients who have received hospital treatment in Daejeon Univ. Cheon-Ahn Korean Hospital. All patients were treated with acupuncture treatment on high frequency acupuncture point (BL25, BL23, BL24, GB30, BL40, BL26, BL60, GB34), physical therapy and herbal medicine and self exercise therapy(Swiss ball exercise, Lumbar stabilization exercise.) We measured visual analogue scale(VAS), Oswestry disability index(ODI), Pain threshold twice(pre-treatment and post-treatment) on 1st day and 5 days later. Results : After being treated, lumbar sprain patients were meaningful improved in VAS, ODI, pain threshold The VAS score, ODI score were statistically decreased after treatment and the pain threshold was statistically increased after treatment. Conclusion : In this study, treatment on frequently adopted acupuncture point and self exercise therapy were effective on lumbar sprain patient.

• Journal of Acupuncture Research
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• v.31 no.3
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• pp.91-102
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• 2014

Objectives : This study was done to determine the effect of Korean medical treatment to patient diagnosed as cauda equina syndrome(CES) suffering from both lower limb dysesthesia, saddle dysesthesia, buttock dysesthesia, dysuria, dyschezia and gait disturbance. Methods : A patient with CES was treated with acupuncture, sweet bee venom pharmacopuncture, herbal medicine from February 2 to April 9 at Department of Acupuncture & Moxibustion, Daejeon Korean Hospital of Daejeon University. Patient received acupuncture treatment($CV_1$, $CV_3$, $CV_4$, $CV_6$, $ST_{36}$, $BL_{31}$, $BL_{32}$, $BL_{33}$, $BL_{34}$) 12 times a week, bee-venom pharmacopuncture($BL_{23}$, $BL_{28}$) was conducted twice a week, herbal medicine(Samilsingihwan decoction) was applied to patient thrice a day for nine weeks. The following symptoms were observed saddle, and lower limb dysesthesia, dysuria, dyschezia and gait disturbance. Results : After treatment, dysesthesia, dysuria, dyschezia and gaiting developed good outcome. But anal reflex remained still. Conclusions : Acupuncture, bee-venom pharmacopuncture, herbal medicine combined treatment might be effective to patients with CES.

• Korean Journal of Acupuncture
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• v.23 no.2
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• pp.89-103
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• 2006

Objectives: Recently, the effect of acupuncture has been approved not only in the East but also in the West, so the interest on acupuncture was greatly improved. Especially, functional magnetic resonance imaging(fMRI) was embossed as the study tool for the mechanism of acupuncture noninvasively and many studies on the mechanism of acupuncture using fMRI were carried out. We archived the fMRI study on the brain activity induced by manual acupuncture at BL62(申脈). Methods: The study was the acupuncture at BL62(申脈) and we acquired 9 fMRI results from 6 persons$(age\;20{\sim}30,\;4\;male\;and\;2\;female)$. These studies employed The block design for mapping brain activity and acupuncture was perfomed at BL62(申脈) on the left foot. Results: The brain related motor function was cerebellum, basal ganglia and cerebral cortex and thalamus connected these elements. In the result of this study, the regions of significant activation in the cerebellum was centered on the spinocerebellum in the anterior lobe, so we presumed that this result showed the input of stimulation by the acupuncture on BL62(申脈). But basal ganglia and cerebral cortex showed the regions of significant activation in the left larger than the right and regions of the cerebral cortex was the motor and sensory cortex. Such a result explained that acupuncture at BL62(申脈) could have influence the motor function and acupuncture at left BL62(申脈) could affect the right side through the activation of the left basal ganglia and cerebral cortex. Conclusions: In the theory of crossing needling at collaterals(繆刺論), it the pathogenic factor invaded in the Yang Heel channel(陽?脈) that was one of the eight Extra meridians(奇經八脈), we recognized the disease of the collateral channel and used contralateral BL62(申脈) for treatment of the Yang Heel channel(陽?脈). Moreover the result of this study could bear the construction that acupuncture at the left BL62(申脈) treats the contralateral lesion and this construction is related to the theory of crossing needling at collaterals(繆刺論).

• Journal of Korean Medicine Rehabilitation
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• v.31 no.4
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• pp.49-63
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• 2021

Objectives This study aimed to investigate the trend in treating fracture with acupuncture and to evaluate the quality of case reports. Methods All case reports of fractures treated with acupuncture were extracted from four Korean web databases. We classified these studies by five fracture sites and investigated frequently used meridian and acupoint, outcome measurements, treatment period. And we assessed the quality of the case reports by the STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) guidelines. Results A total of 33 case reports were included. The outcome measurements were divided into six categories, and the outcome measurements used in more than three studies showed improvement in patient symptoms. The mainly used meridians for each fracture site were as follows: chest and abdomen (GB, LR, CV), back (BL, GB), upper limb (LI, TE), lower Limb (GB, ST, BL, SP). The most commonly used acupoints for each fracture site were as follows: chest and abdomen (Ashi points, GB24, GB25, GB26, LR13, LR14, CV16, CV17, CV18, CV19), back (BL23, BL24, BL25, BL26, BL40, BL51, BL52, BL60, GB34), upper limb (LI4, LI10, LI11, TE3), lower limb (GB34, GB40). According to the STRICTA guidelines, more than 54.54% of the reports were found to be 'not reported' or 'not sufficient' in the following categories: 'response sought', 'description of participating acupuncturist', and 'number of needle insertions per subject per session'. Conclusions The meridians and acupuncture points frequently used for acupuncture treatment of fractures were near the fracture site. Future clinical studies involving acupuncture must be reported in accordance with the STRICTA guidelines to improve transparency and uniformity.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.174-181
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• 2006

Objective : Based on the immunological dysfunction in RA and the immunological feature of Clematis mandshurica Maxim. herbal acupuncture solution (CM-HAS), this study examined whether subcutaneous (s.c.) administration of CM-HAS has anti-inflammatory effects on adjuvant arthritis (AA) in the rat. Methods : Complete Freund's adjuvant was used to induce AA in rats. Secondary paw swelling of AA rats was measured, and polyarthritis index was scored. The administration of CM-HAS (2, 5, 10 mg/kg) to the Sinsu-hyul (BL 23) acupuncture point subcutaneously (s.c.) inhibited the inflammatory response and restored the weight of body and immune organs of AA rats. In this study. inhibitory effect of CM-HAS on cyclooxygenase-2 (COX-2) was evaluated. The plant material selected for this study has been used in Korean medicine for the treatment of various diseases that are considered as inflammatory in nature, e.g. asthma, arthritis, rheumatism, fever, edema, infections, snakebite and related inflammatory diseases. Results : There were significant secondary inflammatory reactions in AA rats, accompanied with the simultaneous decrease of body and immune organs weight. The administration of CM-HAS (2, 5, 10 mg/kg, s.c.) improved the above changes significantly. CM-HAS showed inhibitory activity against COX-2, which supports their traditional uses. In this study, aspirin and indomethacin were used to contrast with CM-HAS as the COX-2 inhibitors. Conclusion: The findings of this study may explain at least in part why CM-HAS has been traditionally used for the treatment of inflammatory conditions in traditional Korean and Chinese medicine.

• Korean Journal of Acupuncture
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• v.28 no.1
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• pp.91-100
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• 2011

Objectives : To classify needling or moxibustion-prohibited acupoints in Emergency Formulas Worth a Thousand in Gold (EFWTG) and Supplement to the Formulas Worth a Thousand in Gold (SFWTG). Methods : We found needling or moxibustion-prohibited acupoints in EFWTG and SFWTG, then investigated the influences of needling or moxibustion-prohibited acupoints on A-B Classic of Acupuncture and Moxibustion. Results : In EFWTG, the needling-prohibited points were LI13, ST17, BL56, TE8, CV8, CV15 and GV24. Acupoints needed careful needling were LU2, ST12, KI2, KI7, TE19, GB3 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST8, ST9, ST17, ST32, ST33, BL6, BL30, TE18, TE23, GB33, GB42, CV5, CV15, GV6, GV15, GV16 and GV17. Acupoints needed careful moxibustion were ST7, ST30, TE21 and GB22. In SFWTG, the needling-prohibited points were LU2, LI13, ST12, ST17, ST32, BL56, KI2, KI7, TE8, TE19, GB3, CV8, CV15, GV24 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST7, ST8, ST9, ST17, ST30, ST32, ST33, BL6, BL30, TE18, TE23, GB22, GB33, GB42, CV5, CV15, GV6, GV15, GV16, GV17 and ijung. Conclusions : There were 7 needling-prohibited points, 7 acupoints needed careful needling, 20 moxibustion-prohibited points, and 4 acupoints needed careful needling in EFWTG, and 15 needling-prohibited points and 24 moxibustion-prohibited points in SFWTG. The needling or moxibustion-prohibited acupoints in A-B Classic of Acupuncture and Moxibustion had a strong influence on those in the two literatures.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.3 no.1
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• pp.85-98
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• 1997

Oriental medicine as a candidate for effective cancer treatment recently gain positive concerns in fields of therapeutic oncology. that is why some herbal medicines have been empirically safer in toxicity than anticancer drugs used in western medicine, and to show excellent therapeutic efficacy in human trial. Thus, these effects by clinically applied-herbs have not yet fully demonstrated in experimental tumor model. This study was initiated to evaluate the antitumor effect of Insambaekhaptang as candidate of antitumor-herbal agent against B16 melanoma metastasized into C57BL/6 mice lung. In experiment to test whether Insambaekhaptang can directly kill cancer cells in vitro or not, Insambaekhaptang showed direct killing action in concentration or higher against B16 melanoma cells using MTT assay, and showed lower IC50. Another experiment to know whether Insambaekhaptang can inhibit growth and metastasis of cancer cell or not, Insambaekhaptang significantly inhibited Solid tumor by intraperiperal injected-melanoma and lung metastasis induced by intravenous injected-melanoma in inbred C57BL/6 mice. When quantitative survival time increasing, we could obtain results that increased 113% in treated by Insambaekhaptang. These results show that Insambaekhaptang can inhibit growth of B16 melanoma cells through various biological mechanisms.

• Korean Journal of Ecology and Environment
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• v.42 no.1
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• pp.58-66
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• 2009

The telemetry of eight adult manchurian trouts (Brachymystax lenok tsinlingensis) in the upper part of the Nakdong River, which is the southern limit of distribution of manchurian trout on the Korean peninsula, was used to examine migration patterns and evaluate characteristics of over-wintering and the spawning season between December, 2007 and May, 2008. Based on the tracking data, the tagged fish showed a limited migration between adjacent pools, moving only up to $8.6m\;day^{-1}$ during the winter season (December to February). Hydraulic conditions of over-wintering pool areas were, ca. 1m depth, slow moving surface water with areas of sand and gravel. The migration of tagged individuals was successful, moving up to $96.2m\;day^{-1}$ during the spawning season. Two tagged individuals (BL4, BL6) exhibited upstream migration, whereas others showed downstream movements. The timing of upstream migration of the two individuals was consistent with an increasing phases of water level and discharge. The fishes migrating toward the down stream moved to the wide pool areas downstream, where they spent the summer season for the growth.

• Journal of Acupuncture Research
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• v.23 no.3
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• pp.1-19
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• 2006

Objectives : This study was carried out to determine the effects of Gamidokwalgisaeng-tang(GDS) oral administration and electro-acupuncture at $BL_{52}$ & $GB_{39}$ on the postmenopausal osteoporosis. Methods: In order to study the effects of the Gamidokwalgisaeng-tang(GDS) oral administration and electro-acupuncture at $BL_{52}$, $GB_{39}$ on osteoporotic rats induced by ovariectomy, body weight, femur weight, uterine weight, serum level of osteocalcin, alkaline phosphatase(ALP), cholesterol, triglyceride, estradiol, androstenedione, testosterone and urinary excretions of calcium & phosphorus were measured. Results : 1. Body weight in all experimental group decreased significantly in comparison with ovariectomized group(OVX). 2. The weight of femur compared with body increased significantly in GDS oral administration and combination treatment group in comparison with ovariectomized group(OVX). 3. Uterine endometrial morphology is caused by ovariectomy and the weight of uterus decreased significantly in control and all experimental group in comparison with sham. 4. The serum level of osteocalcin decreased in all experimental group in comparison with OVX, but significantly in electro-acupuncture and combination treatment group. 5. The serum alkaline phosphatase(ALP) activity decreased in electro-acupuncture and combination treatment group in comparison with OVX, but only significantly in electro-acupuncture group. 6. The serum level of cholesterol increased significantly in OVX in comparison with sham and decreased in all experimental group in comparison with OVX, not insignificantly. The serum level of triglyceride increased in all experimental group in comparison with OVX, not insignificantly. 7. Urinary excretions of calcium and phosphorus decreased significantly in all experimental group in comparison with OVX. Conclusion : We suggest that GDS oral administration and electro-acupuncture at $BL_{52}$ & $GB_{39}$ are available for prevention and curing about the postmenopausal osteoporosis.

• Korean Journal of Acupuncture
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• v.28 no.1
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• pp.53-60
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• 2011

Objectives : Cupping therapy has been used as various treatment methods in oriental medicine clinic for a long time. Specially, Cupping stimulation caused skin hyperpigmentation which has been used as diagnosis method for extravasated blood & inner organs functional disease. But it was difficult to quantitatively measure and analyze the interrelation between extravasated blood and skin hyperpigmentation. The aim of this study is to measure the acupoint's RGB and melanin change pattern by stimulating under fixed 80kPa negative pressure and to evaluate the extravasated blood. Methods : To evaluate extravasated blood, 10 acupoints (left/right BL13, BL15, BL18, BL20, BL23) were stimulated by treatment 80kPa negative pressure for 1 minute. And then we measured the acupoints' skin color change patterns using the color meter, followed by RGB analysis and melanin change pattern. Results and Conclusions : We could observe the correlation of the acupoints' skin color condition related with RGB change pattern. All acupoints' color change degree were different. Regardless of acupoints' color degree due to extravasated blood, we observed in common the fact that RGB values decreased after stimulation and steadily increased according to time. We observed that melanin index increased after stimulation and recovered before stimulation-condition after the lapse of time. In other words, we confirmed the correlation between raised color change degree and $L^*a^*$ index change pattern. Therefore we observed the possibility of charting the $L^*a^*$ index following extravasated blood.