• The Korean Journal of Physiology and Pharmacology
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• 제16권6호
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• pp.379-386
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• 2012

The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic morphine withdrawal in rats. Male rats were exposed to chronic, intermittent, escalating morphine (10~50 mg/kg) for 10 days. After the last morphine injection, depression- and anxiety-like beahvior associated with morphine discontinuation persisted for at least three days during withdrawal without any change in ambulatory activity. Daily BER administration significantly decreased immobility in the forced swimming test and increased open-arm exploration in the elevated plus maze test. BER administration also significantly blocked the increase in hypothalamic CRF expression and TH expression in the locus coeruleus (LC) and the decrease in hippocampal brain-derived neurotrophic factor (BDNF) mRNA expression. Taken together, these findings demonstrated that BER administration significantly reduced morphine withdrawal-associated behaviors following discontinuation of repeated morphine administration in rats, possibly through modulation of hypothalamic CRF and the central noradrenergic system. BER may be a useful agent for treating or alleviating complex withdrawal symptoms and preventing morphine use relapses.

• International journal of advanced smart convergence
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• 제12권4호
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• pp.20-25
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• 2023

Increasing demand for increasing higher data rate in order to solve computationally tasks timely and connecting many user equipment simultaneously have requested researchers to develop novel technology in the area of mobile communications. Intelligent reflecting surface (IRS) have been enabling technologies for commercialization of the fifth generation (5G) networks and the sixth generation (6G) systems. In this paper, we investigate a bit-error rate (BER) analysis on IRS technologies for non-orthogonal multiple access (NOMA) systems. First, we derive a BER expression for IRS-NOMA systems with Rician fading channels. Then, we validate the BER expression by Monte Carlo simulations, and show numerically that BER expressions are in good agreement with simulations. Moreover, we investigate the BER of IRS-NOMA systems with Rician fading channels for various numbers of IRS elements, and show that the BERs improve as the number of IRS elements increases.

• The Korean Journal of Physiology and Pharmacology
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• 제22권2호
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• pp.183-192
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• 2018

Post-traumatic stress disorder (PTSD) is a trauma-induced psychiatric disorder characterized by impaired fear extermination, hyperarousal, anxiety, depression, and amnesic symptoms that may involve the release of monoamines in the fear circuit. The present study measured several anxiety-related behavioral responses to examine the effects of berberine (BER) on symptoms of anxiety in rats after single prolonged stress (SPS) exposure, and to determine if BER reversed the dopamine (DA) dysfunction. Rats received BER (10, 20, or 30 mg/kg, intraperitoneally, once daily) for 14 days after SPS exposure. BER administration significantly increased the time spent in the open arms and reduced grooming behavior during the elevated plus maze test, and increased the time spent in the central zone and the number of central zone crossings in the open field test. BER restored neurochemical abnormalities and the SPS-induced decrease in DA tissue levels in the hippocampus and striatum. The increased DA concentration during BER treatment may partly be attributed to mRNA expression of tyrosine hydroxylase and the DA transporter in the hippocampus, while BER exerted no significant effects on vesicular monoamine transporter mRNA expression in the hippocampus of rats with PTSD. These results suggest that BER had anxiolytic-like effects on behavioral and biochemical measures associated with anxiety. These findings support a role for reduced anxiety altered DAergic transmission and reduced anxiety in rats with PTSD. Thus, BER may be a useful agent to treat or alleviate psychiatric disorders like those observed in patients with PTSD.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제6권10호
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• pp.2493-2508
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• 2012

The performance of a MIMO system with adaptive modulation (AM) and space-time coding over Ricean fading channels for perfect and imperfect channel state information (CSI) is presented. The fading gain value is partitioned into a number of regions by which the modulation is adapted according to the region the fading gain falls in. Under a target bit error rate (BER) constraint, the switching thresholds for AM are given. Based on these results, we derive the calculation formulae of the theoretical spectrum efficiency (SE) and average BER. As a result, closed-form SE expression and accurate BER expression are respectively obtained. Besides, using the approximation of complementary error function, a tightly closed-form approximation of average BER is also derived to simplify the calculation of accurate theoretical BER. Computer simulation shows that the theoretical SE and BER are in good agreement with the corresponding simulation, and the approximate BER is also close to the accurate one. The results show that the AM scheme in Ricean fading channel provides better SE than that in Rayleigh fading channel due to the direct-path propagation, and has performance degradation in SE and BER for imperfect CSI.

• ETRI Journal
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• 제29권6호
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• pp.707-715
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• 2007

In-phase/quadrature (I/Q) imbalances, which are generated by non-ideal transceiver components, are inevitable physical phenomena that cause the performance of practical communication systems to be degraded. In this paper, we provide a new closed-form expression for the bit error rate of hierarchical M-ary phase shift keying with I/Q phase and amplitude imbalances and analyze the effect of I/Q imbalances on BER performance over an additive white Gaussian noise channel.

• International Journal of Internet, Broadcasting and Communication
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• 제13권4호
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• pp.39-47
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• 2021

Lempel-Ziv coding is one of the most famous source coding schemes. The output of this source coding is usually a non-uniform code, which requires additional source coding, such as arithmetic coding, to reduce a redundancy. However, this additional source code increases complexity and decoding latency. Thus, this paper proposes the optimal maximum a-posteriori (MAP) receiver for non-uniform source non-orthogonal multiple access (NOMA) with symmetric superposition coding (SSC). First, we derive an analytical expression of the bit-error rate (BER) for non-uniform source NOMA with SSC. Then, Monte Carlo simulations demonstrate that the BER of the optimal MAP receiver for the non-uniform source improves slightly, compared to that of the conventional receiver for the uniform source. Moreover, we also show that the BER of an approximate analytical expression is in a good agreement with the BER of Monte Carlo simulation. As a result, the proposed optimal MAP receiver for non-uniform source could be a promising scheme for NOMA with SSC, to reduce complexity and decoding latency due to additional source coding.

• International Journal of Internet, Broadcasting and Communication
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• 제14권2호
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• pp.23-29
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• 2022

To improve spectrum and energy efficiency in the fifth generation (5G) wireless channels, intelligent reflecting surface (IRS) transmissions have been envisioned, possibly towards the sixth generation (6G) networks. In this paper, we analyze the bit-error rate (BER) performance of intelligent reflecting surface (IRS) assisted non-orthogonal multiple access (NOMA) systems. First, we derive a closed-form expression of the BER in terms of Q functions. Then we analyze the BER improvement of the IRS NOMA system over the conventional NOMA system with respect to the power allocation. Furthermore, we also demonstrate numerically the BER improvement of the IRS NOMA network over the conventional NOMA network in respect of the number of reflecting devices.

• 한국정보통신학회논문지
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• 제9권5호
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• pp.951-957
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• 2005

다중 사용자 간섭을 고려한 BPSK 데이터 변조 방식을 갖는 초광대역(Ultra-Wide Bandwidth, UWB) 시간 도약(time hopping, TH) 다중 통신 시스템의 정확한 비트 오율(bit error rate: BER)을 계산하는 방법을 제시하였다. UWB-TH BPSK 신호는 약간의 수정을 통하여 기존의 DS-CDMA 신호와 유사함을 보였다. 또한 다중 사용자 간섭(multiple user interference, MUI)는 특성 함수 기법을 이용하여 정확하게 기술하였다. 이들을 바탕으로 TH-BPSK 다중 통신 시스템의 BER을 정확히 계산하였다. 또한, MUI에 대한 기존의 가우시안 근사에 비하여 상당히 정확한 결과를 얻을 수 있는 간단한 근사식을 함께 제시하였다. 본 논문에서 제시한 BER 계산식의 정확성 및 타당성은 시뮬레이션 결과와 비교함으로써 확인하였다.

• 한국전자통신학회논문지
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• 제15권5호
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• pp.881-888
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• 2020

본 논문에서는, 상호작용 이동통신 사용자의 비직교 다중접속에서 강채널 사용자의 저하된 BER 성능을 향상하기 위해 음수의 상관관계 계수 B2S 사상을 제안한다. 먼저, 음수의 상관관계 계수 B2S 사상 수신기의 BER의 폐쇄형 표현식을 유도하고, 이상적인 완벽한 SIC 수신기와 양수의 상관관계 계수 수신기의 BER과 비교하여, B2S 수신기의 BER이 향상되었음을 보여준다. 또한, 이론적인 분석에 기초하여 SNR 이득을 구하여 음수의 상관관계 계수 B2S 사상 수신기의 성능 우수성을 입증한다.

• 한국전자통신학회논문지
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• 제15권5호
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• pp.865-872
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• 2020

5G 이동통신 네트워크에서, 비직교 다중접속은 채널 용량을 높일 수 있는 기술로 각광받고 있다. 비직교 다중접속에서는, 다수 사용자가 채널 자원을 공유하여 신호를 동시에 전송 가능하다. 최근, 강 채널에 대해, 상호 작용 이동통신 사용자의 성능이 비상호작용 이동통신 사용자 비해, 저하되는 연구가 보고되었다. 본 논문에서는, 이러한 문제를 해결하기 위해 ML 수신기를 제안한다. 먼저, ML 수신기의 BER의 폐쇄형 표현식을 유도하고, 이상적인 완벽한 SIC 수신기의 BER과 비교하여, ML 수신기의 BER이 향상되었음을 보여준다. 또한, 이론적인 분석에 기초한 모의실험을 진행하고 ML 수신기의 성능 우수성을 입증한다.