• Title/Summary/Keyword: BC3A

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Efficacy and Safety of Intraveous Iron Sucrose in the Perioperatively Anemic Patients of Gastrectomy (위 절제 수술 전후 빈혈 환자에 있어 철수크로오스의 유효성 및 안전성)

  • Yoo, Moon-Won;Cho, Jae-Jin;Lee, In-Kyu;Ahn, Hye-Seong;Jeong, Sang-Ho;Lee, Hyuk-Joon;Kim, Hyung-Ho;Lee, Kuhn-Uk;Yang, Han-Kwang
    • Journal of Gastric Cancer
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    • v.8 no.1
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    • pp.35-39
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    • 2008
  • Purpose: This study was aimed to evaluate the efficacy and safety of of intravenous iron sucrose ($Venoferrum^{(R)}$) for treating the perioperative anemic gastrectomy patients. Materials and Methods: From September 2006 to February 2007 at Seoul National University Hospital, the gastrectomy patients who displayed perioperative anemia (7.0 g/dl $\leq$ hemoglobin levels (Hb) < 11.0 g/dl) and who were admitted or visited the outpatient clinic of the Department of surgery, were divided into two groups. The preoperative (${\leq}\;2{\sim}3$ weeks before gastrectomy) or postoperative ($\geq$ 1 month after gastrectomy) patients without evidence of acute bleeding were included into Group 1. The immediate postoperative (< 1 month after gastrectomy) patients with stable vital signs were included into Group 2. The age, gender, diagnosis, Hb, hematocrit (Hct), mean corpuscular volume (MCV), serum ferritin (SF), total iron binding capacity (TIBC), serum iron and reticulocyte counts (RC) were evaluated before and after intravenous iron sucrose administration. The adverse effects of drugs were investigated. Results: The number of patients of group 1 and group 2 was 79 and 46, respectively. In group 1, there was a statistically significant difference in the Hb, Hct, MCV, SF, RC and TIBC with each mean change of 1.3 g/dl, 4.1%, 3.1ft, 195 ng/ml, 0.2% and -86.4 ug/dl, respectively. In group 2, there was a statistically significant difference in the Hb, Hct, MCV, SF and RC with each mean change of 1.8 g/dl, 6.1%, 3.4fl, 260 ng/ml and 0.3%, respectively. Two patients (1.6%) suffered local thrombophlebitis as an adverse effect. Conclusion: Intravenous iron sucrose for the perioperative anemia of gastrectomy patients was efficacious in the short period without significant adverse effects.

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Optimum Level of Protein and the Possibility of Replacement of Fish Meal by Soybean Meal in Feeds for Fleshy Shrimp, Penaeus chinensis (대하 (Penaeus chinensis)의 단백질요구량과 단백질원으로서 대두박의 이용)

  • KIM Hyun Jun;HUR Sung Bum
    • Journal of Aquaculture
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    • v.6 no.3
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    • pp.173-186
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    • 1993
  • In order to substitute soybean meal for fish meal, the protein requirement of fleshy shrimp was examined and then the effect of soybean meal supplemented with cuttlefish oil was studied. Different contents of protein in prepared diet had significant effects on the survival rate and growth of fleshy shrimp (P<0.05). With regard to protein content ranging from $25\%\;to\;50\%,\;40\%$ protein showed the best survival rate and fastest growth. The percent survival rates of fleshy shrimp fed diets containing protein levels of 25, 30, 35, 40, 45 and $50(\%)$ were $74.0^d,\; 82.0^{cd},\;91.0^b,\;97.0^a,\;93.0^{ab},\;and\;88.0^{bc}\%(P< 0.05).$ The optimum protein requirements for postlarvae (13-84 mg) and juvenile (0.9-8.1g) were calculated by the broken line method as $40.4\%\;and\;39.9\%$. When soybean meal was substituted $(up\;to\;76\%)$ for fish meal in the prepared diet, the performance' gradually suffered with the increase of soybean meal content, but when cuttlefish oil was added to soybean meal, survival rates were improved with $2.5\%$ cuttlefish oil supplement.

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Effects of Ballet Program Training of Royal Academy of Dance on Body Composition, Physical Fitness and Bone Mineral Density in College Women (로얄 아카데미 발레댄스 프로그램 수행이 여자 대학생의 신체조성, 체력 및 골밀도에 미치는 영향)

  • Kim, Jong-Won;Lee, Mi-Ran;Lee, Kyung-Hee;Kim, Hyung-Jun;Choi, Mun-Ki;Kim, Do-Yeon;Kim, Tae-Un
    • Journal of Life Science
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    • v.19 no.8
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    • pp.1093-1103
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    • 2009
  • The purpose of this study was to analyze the effects of ballet program training at the Royal Academy of dance (RAD) on body composition (BC), physical fitness (PF) and bone mineral density (BMD) in college women. The subjects for this study were 14 females aged 19 to 22, who were divided into the Experimental group (n=7, EG) and the Control group (n=7, CG). The RAD ballet program training was done by 7 subjects (EG), 60 minutes per day, three times a week for 12 weeks. The TBF and %fat significantly decreased and LBM increased in the Experimental group, but all the variables of Body composition in the Control group did not significantly changed. The AMS, Sit ups, STF, SLJ CFB and 1,200 m R & W in the EG significantly increased, but 1,200 m R & W in the CG decreased. The lumbar vertebra (LV), femoral neck (FN), greater trochanter (GT) and ward's triangle (WT) did not significantly change in the EG, but LV, GT and WT in the CG decreased. There was no significant difference in osteopenia for EG, but there were increases in GT and WT for the CG. There was significant correlation between BMDs and body weight, TBF, LBM, %fat, BMI, AMS. There was significant correlation between LV and FN and LV and whole body. In conclusion, regular and continuous RAD training was effective in improving the body composition, physical fitness and bone mineral density. Consequently, RAD training will be effective for preventing osteopenia and osteoporosis, and for improving the health-related fitness for college and middle-aged women.

Hypothermia Effect on Apoptotic Neuronal Death in Traumatic Brain Injury Model

  • Yoo, Do-Sung;Lee, Soon-Kyu;Huh, Pil-Woo;Han, Young-Min;Rha, Hyung-Kyun;Kim, Dal-Soo
    • Journal of Korean Neurosurgical Society
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    • v.38 no.3
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    • pp.215-220
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    • 2005
  • Objective : Many researchers believe that the hypothermia shows neuro-protective effect on brain injury. To understand the molecular mechanism of the hypothermic treatment, this study investigated its effects on the expression of cell death or survival related proteins such as p53, Bcl-2 and Bax in the rat traumatic brain injury[TBI] model. Methods : Twenty rats [Spraque Dawley, $200{\sim}250g$] were subjected to the brain injury of moderate severity [$2.4{\sim}2.6atm$] using the fluid percussion injury device and five rats were received only same surgery as controls. During 30minutes after the brain injury, the hypothermia group was maintained the body temperature around $34^{\circ}C$ while the control group were maintained that of $36^{\circ}C$. Five rats in each group were sacrificed 12h or 24h after brain injury and their brain sections was analyzed for physical damages by H-E stains and the extent of apoptosis by TUNEL assay and immunohistochemical stains. The tissue damage after TBI was mainly observed in the ipsilateral cortex and partly in the hippocampus. Results : Apoptosis was observed by TUNEL assay and the Bax protein was detected in both sample which harvested 12h and 24h after TBI. In the hypothermia treatment group, tissue damage and apoptosis were reduced in HE stains and TUNEL assay. In hypothermia treatment group rat shows more expression of the Bcl-2 protein and shows less expression of the Bax protein, at both 12h and 24h after TBI. Conclusion : These results show that the hypothermia treatment is an effective treatment after TBI, by reducing the apoptotic process. Therefore, it could be suggested that hypothermia has a high therapeutic value for treating tissue damages after TBI.

Estimating Climate Pollutants Emissions and Service Demands considering Socio-economic Change: Residential·Commercial Sector, Transportation Sector, Industrial Sector (사회경제 변화를 고려한 서비스 수요 및 기후변화 유발물질 배출량 예측: 가정·상업부문, 교통부문, 산업부문을 중심으로)

  • Park, Jin-Han;Lee, Dong-Kun;Lee, Mi-Jin;Park, Chan;Jung, Tae-Yong;Kim, Sang-Kyun;Hong, Sung-Chul;Baek, So-Jin;Lee, Jang-Hoon
    • Journal of Climate Change Research
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    • v.6 no.4
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    • pp.291-302
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    • 2015
  • Vulnerability due to climate change depends on the concentration of carbon dioxide emissions over several upcoming decades. The objective of this study is to estimate the concentration of greenhouse gases and air pollutants in 2100, while also accounting for expected socio-economic changes in Korea. First, we intend to prepare scenarios for possible socioeconomic changes in Korea: business as usual (BAU), high growth and low growth. Secondly, we aim to predict services demands in residential?commercial sector, transportation sector, industrial sector for each scenarios. Finally, the emissions of LLGHG and SLCP will be estimated on the basis of the predicted service demands. The study results project that in Korea, LLGHG emissions will be approximately $660Mt\;CO_2\;eq$. and SLCP emissions will be approximately 3.81 Mt, -including black carbon (BC) by 2100. The transportation and industrial sectors are the major source for LLGHG emissions, and the residential and commercial sector serve as the SLCP source. Later, additional studies on the cost and benefit of mitigation should be carried out by comparing the reduced use of materials that cause climate change as a result of reduction policies and the socioeconomic cost.

A Study on DNA Polymorphism of the Bovine c-KIT Receptor Gene (소 c-KIT Receptor 유전자의 다형성에 관한 연구)

  • Jang, Y.S.;Kim, T.H.;Yoon, D.H.;Park, E.W.;Lee, H.W.;Lee, H.K.;Cheong, I.C.
    • Journal of Animal Science and Technology
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    • v.44 no.6
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    • pp.653-660
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    • 2002
  • We considered KIT gene as a candidate gene for the white-spotting pattern in cattle. This study was carried out to detect genetic variation of c-KIT receptor gene and to investigate association between the mutation and the white-spotting pattern in cattle. PCR-RFLP analysis within intron 6 of c-KIT receptor gene were performed with 8 cattle breeds including Hanwoo, Angus, Brown Swiss, Charolais, Hereford, Holstein, Limousin and Simmental. When PCR product of approximately 2,440 bp including intron 6 of c-KIT receptor gene was sequenced, four nucleotide substitutions were found within intron 6 of the bovine c-KIT receptor gene. In PCR-RFLP analysis, three alleles (A, B and C), two alleles (A and B) and two alleles (A and B) at each locus were identified by MspⅠ, BsrBⅠ and NdeⅠ, respectively. Although frequencies of allele at each locus were different among cattle breeds, we could not get any evidence related with white or white spotting phenotypes in these mutations on intron 6 of c-KIT receptor gene. However, we can not entirely exclude the possibility that c-KIT receptor gene is responsible for white spotting phenotype in cattle. Thus, further studies need to detect other mutations in c-KIT receptor gene and to test association of those mutations and coat color phenotypes in cattle.

Geological Structure and Deformation History in the Gwangju area, Gyeonggi-do, Korea (경기도 광주시 일대의 지질구조와 변형사)

  • Lee Hee-Kwon;Kim Man-Kwang
    • The Journal of the Petrological Society of Korea
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    • v.14 no.2 s.40
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    • pp.108-115
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    • 2005
  • Gyeonggi metamorphic complex in the Gwangju area include banded biotite gneiss and quartzofeldspathic gneiss. Detailed structural analysis suggests that structural elements in the study area were formed by at least five phase of deformations. Penetrative compositional foliations(S1) formed in the banded gneiss during the first metamorphism and deformation (D1). After intrusion of plutonic rocks, the second deformation (D2) produced S2 foliations in the banded gneiss and quartzofeldspathic gneiss during the second metamorphism. D3 structures are represented by isoclinal folds (F3) whose axial surfaces are parallel to S3 foliations. The N-S oriented shortening (D4) was accommodated by closed upright F4 fold with about 100m of axial surface separation. F4 fold is refolded by regional F5 folding resulting in different orientation and fold style of F4 fold according to the position of F5 fold. The F4 fold with tight interlimb angle is subparallel to the axial surface (north-south) of F5 fold in the core of the F5 fold. In contrast the F4 fold trends northeast in the western limb and northwest in the eastern limb of F5 fold. The interlimb angle is larger in the limbs than that in the core of F5 fold. The trace of foliations is constrained by mainly F4 and F5 folds. Joint fanning around fold is developed in the limbs of F5 fold and bc joints are dominant in the hinge area of F5 fold. A strike-slip fault had developed in tile central part of the study area after F5 folding. The orientation of joint and foliation is rotated anticlockwise about $15^{\circ}$ by the landslide occurred during the Quaternary.

Effects of Dropwort Powder on the Quality of Castella (미나리가루의 첨가가 Castella의 품질에 미치는 영향)

  • Park, Sang-Jun;Lee, Kwang-Suck;An, Bye-Lyung
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.6
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    • pp.834-839
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    • 2007
  • This study was designed to determine the optimal ratio of dropwort powder in castella by adding the powder at levels of 0, 3, 6, 9, and 12% respectively. The properties of the castella were analyzed by specific gravity, specific volume, color determinations, texture properties and sensory evaluation. The Specific gravity increased with increasing amount of dropwort powder. However, the specific volume decreased with increasing dropwort powder. For the color values, as more dropwort powder was added, the L-value decreased. The castella with 9% dropwort powder had a higher hardness, gumminess, and chewiness. A sensory panel perceived that the external and internal color of the castella become darker with the dropwort powder substitution and the grain size decreased with increasing amount dropwort powder, while sweet taste showed no significant difference. The order of overall preference was DP 9>DP 6>DP 12>CON>DP 3. Therefore, the substitution of 9% of wheat flour with dropwort powder was recommended in the production of castella.

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Study on the Distributional Characteristics and Classification of Quaternary Monogenetic Volcanoes in Jeju Island, Korea (제주도에 분포하는 제4기 단성화산체의 형태적 분류 및 분포 특성 연구)

  • Lee, Jeong-Hyun;Yun, Sung-Hyo
    • The Journal of the Petrological Society of Korea
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    • v.21 no.4
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    • pp.385-396
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    • 2012
  • Jeju island is the biggest volcanic island in Korea and there are over 455 Quaternary monogenetic volcanoes, of which approximately 373 volcanoes(82.0%) are cinder cones. Other volcanic forms in the island include sharp-pointed lava cone without crater(9 volcanoes; 2.0%), shield volcanoes(27 volcanoes; 5.9%), tuff rings(17 volcanoes; 3.7%), tuff cones(3 volcanoes; 0.7%), a maar(1 volcano; 0.2%) and lava domes(25 volcanoes; 5.5%). The monogenetic volcanoes include 15 small nested cinder cones(aloreum). The monogenetic volcanoes are more abundant in the eastern part of the island than in the western part. If the main cause of the weathering such as precipitation affected the shape of the monogenetic volcanoes, more monogenetic volcanoes(BC, CC, DC, etc.) are supposed to be present in the southern part that have more precipitation than in the northern part. But the distribution of the monogenetic volcanoes shows no difference between the southern and the northern parts. So we suggest that the difference of the climatic conditions did not affect the distribution or the shape of cinder cones. Tuff rings, tuff cones and a maar are distributed beneath the island or in the low-altitude areas along the shore although cinder cones are distributed in the interior of the island. This means that the volcanic activity which formed the monogenetic volcanoes resulted from either phreatomagmatic eruption or magmatic (hawaiian or strombolian) eruptions depending on the reaction with water (underground water or shallow waters). The distribution of the monogenetic volcanoes according to the altitude shows that 253(55.6%) volcanoes occur in low-lying coastal areas at an altitude below 300 m, 110(24.2%) in a middle mountainous area at an altitude between 300~600 m and 92(20.2%) in a high mountainous area at an altitude above 600 m. So more than half of monogenetic volcanoes are distributed in low-lying coastal areas.

Embryonic and Larval Development of Slender Catfish, Silurus microdorsalis Mori, 1936, Endemic to Korea (한국 고유종 미유기(Silurus microdorsalis Mori, 1936)의 난 발생 및 자치어 형태발달)

  • Kang-Rae Kim;Yeong-Ho Kwak;Mu-Sung Sung;Heon Yang;Seong-Jang Cho;Bong Han Yun;In-Chul Bang
    • Korean Journal of Ichthyology
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    • v.35 no.2
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    • pp.91-100
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    • 2023
  • The early life history of Silurus microdorsalis living in Jahocheon Stream was studied by observing egg and morphological development. Live fish were captured in June 2018, then reared in a circulating filtration system under a 14L : 10D photoperiod with a water temperature of 18℃. To artificially induce spawning, females were injected with 0.5 mL of Ovaprim (Syndel, Nanaimo, BC, Canada) per kg of body weight, and males were injected with 10,000 IU/kg body weight of human chorionic gonadotropin. Approximately 15 h later, eggs were artificially inseminated by the dry method. Mature eggs were light pale yellow, which separated them from immature eggs. Fertilized eggs were 2.16±0.06 mm (n=8) in diameter and fully hatched at 181 h after fertilization. The fertilization rate was 63.1±2.2%, and 10.0±3.7% of the embryos were malformed at 18℃. The rates of development were 181 h at 18℃, 109 h at 21℃, and 76 h at 24℃. The larval size immediately after hatching was 4.64±0.22 mm (n=8), and the larvae displayed negative phototaxis at 1 day after hatching. The total larval length on 7 days after hatching was 12.47±0.53 mm, with 25~30 basal anal fin rays and 14~16 basal caudal fin rays observed. The total larval length was 14.13±0.51 mm on 9 days after hatching, and approximately 90% of the black endoplasmic reticulum was deposited on the head and body. The dorsal fin had formed, and a single basal body was observed. On 15 days after hatching, the total larval length was 16.69±0.31 mm; the number of basal caudal fin rays (18 poles) was an integer because 2 dorsal fin basal rays and 60~63 anal fin basal rays were observed. The total larval length was 28.96±1.10 mm on 50 days after hatching; the numbers of caudal fins (n=18), dorsal fins (n=3), pectoral fins (n=11), and anal fin basal rays (n=67~73) were integers.