• Korea Trade Review
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• v.45 no.5
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• pp.141-159
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• 2020

Container terminals at Gwangyang Port are operated by three container operators: A, B and C. Ultimately, there is consensus that a single operator should operate all terminals so that economies of scale can be achieved even in the operation of the container terminal. Integration between operators has a positive effect on both operators and shipping companies. From the operator's point of view, overlapping fixed costs between operators can be unified, reducing overall costs and utilizing spare facilities. On the other hand, from the viewpoint of the shipping company, it is possible to ensure stable use of the port facilities and always allow berthing, reduce days on demurrage and ship waiting, and provide one-stop service for work. However, existing cases of operators' integration or relocation of terminals remained to estimate the expected effects of alternatives, emphasizing only the financial point of view. The port terminal is a large system, and it is important to consider that it is an aggregate of major logistics facilities and equipment. Moreover, if the estimation can be made by quantifying the expected effect, the justification of the terminals' relocation can be further emphasized. Therefore, it is very important to estimate the expected effect from the viewpoint of systemic operation. Moreover, the need for operators' integration can be further emphasized if it can be estimated through quantification of expected effects. Currently, three alternatives are considered as alternatives to the terminals' relocation, and in this study, the optimal plan was derived for the 3 alternatives by the linear planning model of the minimum shuttle transportation cost in the terminal. The optimal plan is alternative 2, which shows the most advantageous integration effect in terms of expected effects. Alternative 2 integrates the B terminal into the C terminal, and the A terminal operates independently as it is.

• BMB Reports
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• v.40 no.1
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• pp.44-52
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• 2007

Kinesins, as a kind of microtubule-based motor proteins, have a conserved microtubule-binding site in their motor domain. Here we report that two homologous kinesins in Arabidopsis thaliana, KatB and KatC, contain a second microtubule-binding site in their tail domains. The prokaryotic-expressed N-terminal tail domain of the KatC heavy chain can bind to microtubules in an ATP-insensitive manner. To identify the precise region responsible for the binding, a serious of truncated KatC cDNAs encoding KatC N-terminal regions in different lengths, KatC1-128, KatC1-86, KatC1-73 and KatC1-63, fused to Histidine-tags, were expressed in E. coli and affinity-purified. Microtubule cosedimentation assays show that the site at amino acid residues 74-86 in KatC is important for microtubule-binding. By similarity, we obtained three different lengths of KatB N-terminal regions, KatB1-384, KatB1-77, and KatB1-63, and analyzed their microtubule-binding ability. Cosedimentation assays indicate that the KatB tail domain can also bind to microtubules at the same site as and in a similar manner to KatC. Fluorescence microscopic observations show that the microtubule-binding site at the tail domain of KatB or KatC can induce microtubules bundling only when the stalk domain is present. Through pull-down assays, we show that KatB1-385 and KatC1-394 are able to interact specifically with themselves and with each other in vitro. These findings are significant for identifying a previously uncharacterized microtubule-binding site in the two kinesin proteins, KatB and KatC, and the functional relations between them.

• Molecules and Cells
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• v.39 no.5
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• pp.403-409
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• 2016

NME1 is a well-known metastasis suppressor which has been reported to be downregulated in some highly aggressive cancer cells. Although most studies have focused on NME1, the NME1 gene also encodes the protein (NME1L) containing N-terminal 25 extra amino acids by alternative splicing. According to previous studies, NME1L has potent anti-metastatic activity, in comparison with NME1, by interacting with $IKK{\beta}$ and regulating its activity. In the present study, we tried to define the role of the N-terminal 25 amino acids of NME1L in $NF-{\kappa}B$ activation signaling. Unfortunately, the sequence itself did not interact with $IKK{\beta}$, suggesting that it may be not enough to constitute the functional structure. Further construction of NME1L fragments and biochemical analysis revealed that N-terminal 84 residues constitute minimal structure for homodimerization, $IKK{\beta}$ interaction and regulation of $NF-{\kappa}B$ signaling. The inhibitory effect of the fragment on cancer cell migration and $NF-{\kappa}B$-stimulated gene expression was equivalent to that of whole NME1L. The data suggest that the N-terminal 84 residues may be a core region for the anti-metastatic activity of NME1L. Based on this result, further structural analysis of the binding between NME1L and $IKK{\beta}$ may help in understanding the anti-metastatic activity of NME1L and provide direction to NME1L and $IKK{\beta}$-related anti-cancer drug design.

• The Journal of the Korea institute of electronic communication sciences
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• v.4 no.1
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• pp.46-52
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• 2009

This paper design QHA(quadrifilar helical antenna) to receive efficiently Satellite-Digital Multimedia Broadcasting video signal. It is designed as quadrifilar structure with phase variation $0^{\circ}C$, $90^{\circ}C$, $180^{\circ}C$, $270^{\circ}C$ to obtain circular polarization. Upper gap, turn number and height of QHA are varied to obtain optimization dimensions. Optimization dimensions are gap=2.2mm, turn number=0.9, height=42mm and input reflection coefficient is approximately -5.8dB. Designed QHA can be applied to Satellite-DMB terminal.

• Journal of Hospice and Palliative Care
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• v.18 no.4
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• pp.306-313
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• 2015

Purpose: This study was performed to explore factors that influence attitudes toward terminal care in nursing students. Methods: Data were collected using a self-reported questionnaire filled by 175 nursing students at a university in a metropolitan city B. Data were analyzed using descriptive analysis, t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression with the SPSS/WIN 22.0 program. Results: Attitudes toward terminal care in nursing students was significantly correlated with communication competence (r=0.438, P<0.001), spirituality (r=0.374, P<0.001), and gratitude (r=0.318, P<0.001). Communication competence explained 18.7% of the variance in attitudes toward terminal care. Conclusion: The study shows communication competence is an important factor for attitudes toward terminal care in nursing students. Therefore, it is necessary to develop a communication competence enhancement program to foster nursing students with appropriate attitudes toward terminal care.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.5
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• pp.821-831
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• 2006

In this paper we researched on the development methods and design of the B-ISDN protocol embedded Internet-Phone PBX System for the previous telephone exchange and communication. We designed the structure of the user terminal md exchange server of the Internet-Phone PBX System, defined message and data structure for call control, and designed call control message flows between sender and receiver terminal for user's communication.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.05a
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• pp.14-23
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• 2002

Development of oligodendrocytes and the generation of myelin internodes within the spinal cord depends on regional signals derived from the notochord and axonally derived signals. Neuregulin (NRG)-1, localized in the floor plate as well as in motor and sensory neurons, is necessary for normal oligodendrocyte development. Oligodendrocytes respond to NRGs by activating members of the erbB receptor tyrosine kinase family. Here, we show that erbB2 is not necessary for the early stages of oligodendrocyte precursor development, but is essential for proligodendroblasts to differentiate into galactosylcerebroside-positive (GalC+) oligodendrocytes. In the presence of erbB2, oligodendrocyte development is normal. In the absence of erbB2 (erbB2-/-), however, oligodendrocyte development is halted at the proligodendroblast stage with a >10-fold reduction in the number of GalC+ oligodendrocytes. ErbB2 appears to function in the transition of proligodendroblast to oligodendrocyte by transducing a terminal differentiation signal, since there is no evidence of increased oligodendrocyte death in the absence of erbB2. Furthermore, known survival signals for oligodendrocytes increase oligodendrocyte numbers in the presence of erbB2, but fail to do so in the absence of erbB2. Of the erbB2-/- oligodendrocytes that do differentiate, all fail to ensheath neurites. These data suggest that erbB2 is required for the terminal differentiation of oligodendrocytes and for development of myelin.

• Proceedings of the KIEE Conference
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• 1987.07b
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• pp.994-998
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• 1987

We calculated the expected length of jumper wires on MDF(Main Distribution Frame) in case of random jumper assignment, and from the calculated results we considered an optimal method of terminal arrangement and terminal expansion for keeping the length of jumper wires short, where MDF is a large frame-work installed in a telephone office for accommodating the terminals which are used for connecting the outside facilities to the inside facilities of the telephone office. We also showed the jumper saving effect in modular frames.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.51 no.8
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• pp.482-492
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• 2002

This paper deals with overvoltage stresses in the field circuit of synchronous machine connected to HVDC terminal. A load rejection of the HVDC may cause generator in the station to become self-excited, resulting in a severe system overvoltage. This paper shows that violent field current oscillations can be produced by resonance between the machine inductance and the terminal capacitance. As most conventional excitation system do not allow reverses current, new topology of excitation system to allow reverse current is proposed. the proposed system can limit the rate of rise of terminal voltage during conditions of self excitation. Apart from these simulations, the nature(Magnitude and frequency) of the field transient state is explained mathematically. Finally, the EMTDC program is used for the simulation studies.

• The Korean Journal of Food And Nutrition
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• v.4 no.2
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• pp.161-166
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• 1991

The blocked N-terminus and N-terminal sequence of soybean B-amylase were aetermined by analyzing the acidic peptides derived on peptic digestion of the enzyme. The acidic peptides were separated from the digest on a Dowex 50$\times$2 column(1X5cm) and purified by reversed phase-high performance liquid chromatography(RP-HPLC). The major acidic peptide, PEP-1, was a heptapeptlde. The N-terminal 7 amino acid sequence of soybean B-amylase was deduced to be acetyl-Ala-Thf-Ser-Asp-Ser-Asn-Met- from the results of sequence analysis of PEP-1 and amino acid analysis of other acidic peptides.