• BMB Reports
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• 제53권9호
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• pp.449-452
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• 2020

The inner ear is a complex and delicate structure composed of the cochlea and the vestibular system. To maintain normal auditory function, strict homeostasis of the inner ear is needed. A proper immune response against infection, thus, is crucial. Also, since excessive immune reaction can easily damage the normal architecture within the inner ear, the immune response should be fine regulated. The exact mechanism how the inner ear's immune response, specifically the innate immunity, is regulated was unknown. Recently, we reported a protein selectively localized in the inner ear during bacterial infection, named cochlin, as a possible mediator of such regulation. In this review, the immunological function of cochlin and the mechanism behind its role within inner ear immunity is summarized. Cochlin regulates innate immunity by physically entrapping pathogens within scala tympani and recruiting innate immune cells. Such mechanism enables efficient removal of pathogen while preserving the normal inner ear structure from inflammatory damage.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2006년도 춘계학술발표대회 논문집
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• pp.99-100
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• 2006

The concept of dental clinic have been changed along the advanced dental science to meet the need of setting up high-technology-digital appliances. As the general idea about the dental clinic has been changed from systematic connection, the expansion of zoning needs to become more accurate and mote detailed. In the spacious waiting room. the interment cafe has been established to supply the information services, and the various multi-imaged channels, which were built in, will relieve the boredom of the waiting time. The formation of water space leads to the effect of humidification and makes parents share visual and auditory sympathy All of the unit-chairs attached cameras in the consultation room enables people to diagnose more quickly and precisely through the computerized system. Partitions have been set of to put it in and to help diagnosis process to be done smoothly in the formational space. The whole atmosphere is intended to be harmony with the natural surroundings in Je-Ju. It will inspire people visiting this clinic to image the deep blue sea in Je-Ju. By using projective non-material a lot, especially material wooden windows and doors, it is believed to create the bright and stable atmosphere. It will lead patients feel comfortable.

• 한국정보통신학회논문지
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• 제4권5호
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• pp.1017-1025
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• 2000

인간의 청각시스템은 두 가지 요소 즉, ITD(Interaural Time Difference)와 IID(Interaural Intensity Difference)를 처리하여 음원의 위치와 추적을 하고 있다. 본 연구에서는 음원의 위치 검출을 위하여 ITD와 IID 뿐만 아니라 이전의 위치 정보를 이용하여 정확한 음원의 방향을 결정할 수 있는 TEPILD(Time Energy Previous Integration Location Detector) 모델을 제안하였다. TEPILD 모델에서 time function generator는 ITD, energy function generator는 IID를 처리할 수 있도록 하였다. 음원은 정현파(500Hz,1kHz, 2kHz, 3kHz), White noise, Pink noise, News, Music으로 하고 음원의 방향은 right, front right, front, front left, left로 하였다. 실험 결과 전체 평균 정확도가99.2로 좋은 결과를 얻을 수 있었으며, TEPILD가 음원 위치 검출기에 이용될 수 있음을 확인하였다.

• 한국소음진동공학회논문집
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• 제18권8호
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• pp.823-831
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• 2008

Since it needs the light computational load and small database, sound source localization method using time delay of arrival(TDOA method) is applied at many research fields such as a robot auditory system, teleconferencing and so on. Researches for time delay estimation, which is the most important thing of TDOA method, had been studied broadly. However studies about factors for time delay estimation are insufficient, especially in case of real environment application. In 1997, Brandstein and Silverman announced that performance of time delay estimation deteriorates as reverberant time of room increases. Even though reverberant time of room is same, performance of estimation is different as the specific part of signals. In order to know that reason, we studied and analyzed the factors for time delay estimation using speech signal and room impulse response. In result, we can know that performance of time delay estimation is changed by different R/D ratio and signal characteristics in spite of same reverberant time. Also, we define the performance index(PI) to show a similar tendency to R/D ratio, and propose the method to improve the performance of time delay estimation with PI.

• 정보통신설비학회논문지
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• 제10권4호
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• pp.143-147
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• 2011

The system using augmented reality can save the time and cost. It is verified in various fields under the possibility of a technology by solving unrealistic feeling in the virtual space. Therefore, augmented reality has a variety of the potential to be used. Generally, multimodal senses such as visual/auditory/tactile feed back are well known as a method for enhancing the immersion in case of interaction with virtual object. By adapting tangible object we can provide touch sensation to users. a 3D model of the same scale overlays the whole area of the tangible object; thus, the marker area is invisible. This contributes to enhancing immersive and natural images to users. Finally, multimodal feedback also creates better immersion. In this paper, sound feedback is considered. By further improving immersion learning augmented reality for children with the initial step learning content is presented. Augmented reality is in the intermediate stages between future world and real world as well as its adaptability is estimated more than virtual reality.

• Clinical and Experimental Pediatrics
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• 제53권1호
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• pp.14-20
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• 2010

Cytomegalovirus (CMV) is currently the most common agent of congenital infection and the leading infectious cause of brain damage and hearing loss in children. Symptomatic congenital CMV infections usually result from maternal primary infection during early pregnancy. One half of symptomatic infants have cytomegalic inclusion disease (CID), which is characterized by involvement of multiple organs, in particular, the reticuloendothelial and central nervous system (CNS). Moreover, such involvement may or may not include ocular and auditory damage. Approximately 90% of infants with congenital infection are asymptomatic at birth. Preterm infants with perinatal CMV infection can have symptomatic diseases such as pneumonia, hepatitis, and thrombocytopenia. Microcephaly and abnormal neuroradiologic imaging are associated with a poor prognosis. Hearing loss may occur in both symptomatic and asymptomatic infants with congenital infection and may progress through childhood. Congenital infection is defined by the isolation of CMV from infants within the first 3 weeks of life. Ganciclovir therapy can be considered for infants with symptomatic congenital CMV infection involving the CNS. Pregnant women of seronegative state should be counseled on the importance of good hand washing and other control measures to prevent CMV infection. Heat treatment of infected breast milk at $72{^{\circ}C}$ for 5 seconds can eliminate CMV completely.

• 한국인터넷방송통신학회논문지
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• 제16권5호
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• pp.111-116
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• 2016

미래창조과학부의 정보격차 실태조사에 따르면 장애인의 스마트폰 보유율은 일반인의 1/3 수준에 머물러 있어 장애인의 정보접근성은 비장애인에 비해 현저히 떨어지는 실정이다. 본 논문은 청각장애인의 모바일 음성 통화를 보다 편리하게 사용할 수 있도록 도와주는 어플리케이션인 CallHelper를 개발하였다. CallHelper는 전화가 오면 자동으로 구동되어 상대방의 전화음성을 텍스트로 실시간 번역하여 모바일 화면에 출력하고, 상대방의 음성에서 감정을 추론하여 이모티콘으로 시각화해서 표시하며, 음성과 번역된 텍스트, 감정을 동시에 저장하여 추후 번역결과를 확인해 볼 수 있도록 하는 어플리케이션이다.

• 말소리와 음성과학
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• 제9권3호
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• pp.67-74
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• 2017

An increase in speech intelligibility has been found in Clear Speech compared to conversational speech. Clear Speech is defined by decreased articulation rates and increased frequency and length of pauses. The objective of the present study was to investigate improvement in immediate speech intelligibility in 10 patients with Parkinson's disease (age range: 46 to 75 years) using Clear Speech. This experiment has been performed using the Phonatory Aerodynamic System 6600 after the participants read the first sentence of a Sanchaek passage and the "List for Adults 1" in the Sentence Recognition Test (SRT) using casual speech and Clear Speech. Acoustic and aerodynamic parameters that affect speech intelligibility were measured, including mean F0, F0 range, intensity, speaking rate, mean airflow rate, and respiratory rate. In the Sanchaek passage, use of Clear Speech resulted in significant differences in mean F0, F0 range, speaking rate, and respiratory rate, compared with the use of casual speech. In the SRT list, significant differences were seen in mean F0, F0 range, and speaking rate. Based on these findings, it is claimed that speech intelligibility can be affected by adjusting breathing and tone in Clear Speech. Future studies should identify the benefits of Clear Speech through auditory-perceptual studies and evaluate programs that use Clear Speech to increase intelligibility.

• 대한치과마취과학회지
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• 제10권1호
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• pp.45-49
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• 2010

Adrenoleukodystrophy (ALD) is a rare X-linked genetic disorder associated with various central nervous system problems and adrenal insufficiency. It is common in childhood and symptoms include loss of previously acquired neurological abilities, seizures, ataxia, Addison's disease as well as degeneration of visual and auditory function. These children frequently require anesthesia during imagining procedure such as MRI or during some surgical procedures like gastrostomy. There is special need for careful management because of numerous anesthetic challenges like difficulty in cooperation, seizure disorders, life-threatening airway obstruction, copious oral secretion and possibility of aspiration. In addition, adrenal involvement and hypofunction must be considered for safe anesthesia management. We report a successful anesthetic management in a patient with ALD for dental procedures.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 컴퓨터소사이어티 추계학술대회논문집
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• pp.243-246
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• 2003

In this paper, we propose a new digital audio watermarking technique with the wavelet transform. The watermark is embedded by eliminating unnecessary information of audio signal based on human auditory system (HAS). This algorithm is an audio watermarking method, which does not require any original audio information in watermark extraction process. In this paper, the masking effect is used for audio watermarking, that is, post-tempera] masking effect. We construct the window with the synchronization signal and we extract the best frame in the window by using the zero-crossing rate (ZCR) and the energy of the audio signal. The watermark may be extracted by using the correlation of the watermark signal and the portion of the frame. Experimental results show good robustness against MPEG1-layer3 compression and other common signal processing manipulations. All the attacks are made after the D/A/D conversion.