• Title/Summary/Keyword: AtPR4

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A Study on the Perception of English Rhythm and Intonation Structure by Korea University Students (대학생의 영어 리듬과 억양구조 인식에 대한 연구)

  • Park Joo-Hyun
    • Proceedings of the KSPS conference
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    • 1997.07a
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    • pp.92-114
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    • 1997
  • This study is aimed to grasp the actual problems of the perception of English rhythm and intonation structure by Korean University students who have studied English in the secondary schools for the past six years, and to establish the systems of English rhythm and intonation structure for the Korean students of English. For this study, the listening test is provided, and 100 students are chosen as the subjects of the study. The noticeable findings are summarized as follows: (1) Koreans perceive the words stress comparatively well in nonsense words, unfamiliar place names, and familiar word. (2) Koreans do not perceive the isochrony of English rhythm well enough. The perception of the sentence stress is very unstable, especially in the sentence involved in polysyllabic words, compound words, and 'emphatic stress' pr 'contrastive stress'(or in the different rhythmic patterns). (3) Koreans do not perceive the nucleus well enough. The perception of the nucleus is more stable in content words than in function words, at the end of a sentence than in the middle of a sentence, and in monosyllabic words than in the polysyllabic words. (4) Koreans do not perceive the boundary(or pause) of intonation group well enough. The perception of the pause is unstable in the long or complex sentence. (5) Koreans discriminate the meaning of English word stress comparatively well, especially in disyllabic words. But the discrimination is somewhat unstable in polysyllabic words and between 'adjective' and 'verb' (6) Koreans' discrimination of the intonation meaning is below the level. Koreans do not perceive the differences of intonation meaning according to the pitch accent or the focus. In conclusion, the writer will propose the procedures for the teaching of rhythm and intonation in the following order: word stress drill longrightarrowstressed and reduced syllables drilllongrightarrowrhythm group drilllongrightarrowthe varying rhythm drilllongrightarrowsentence stress drilllongrightarrownucleus drill longrightarrowintonation group drilllongrightarrowlong utterance drill of more than two intonation group.

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The Extracts of Kalopanax pictus Nakai. for Inhibitory Effects on HIV-1 and Its Essential Enzymes (Human Immunodeficiency Virus Type Ⅰ에 대한 음나무 추출물의 억제활성)

  • Yu Young Beob;Shim Bum Sang;Ahn Kyoo Seok;Choi Seung Hoon;Park Jong Cheol;Miyashiro H.;Hattori M.
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.4
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    • pp.1129-1133
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    • 2004
  • For the purpose of developing new anti-HIV agents from natural sources, the extracts of Kalopanax pictus were tested for their inhibitory effects on HIV-1 replication and its essential enzymes as the reverse transcriptase (RT). protease and α-glucosidase. In the assay of HIV-1-infected human T-cell line, water extracts of stem and leafstalk inhibited the HIV-1-induced cytopathic effects with Ie (inhibitory concentration) of 25 and 50㎍/㎖, respectively. Moreover water extracts (100㎍/㎖) of stem and leafstalk showed strong activity of 80% and 90% on anti-HIV-1 RT using Enzyme Linked Oligonucleotide Sorbent Assay (ELOSA) method. In the HIV-1 protease inhibition assay, aqueous stem extract inhibited the activity of the enzyme to cleave an oligopeptide, resembling one of the cleavage sites in the viral polyprotein which can only be processed by HIV-1 protease with 58%, but no glucosidase inhibitory activities. We found out this result, for these samples it is possible that the inhibition of the viral replication in vitro is due to the inhibition at least one of RT and protease. It would be of great interest to identify the compounds which are responsible for this inhibition, since all therapeutically useful agent up to date are RT, PR and α-glucosidase inhibitors.

Properties of MFS capacitors with various gate electrodes using $LiNbO_3$ferroelectric thin film ($LiNbO_3$ 강유전체 박막을 이용한 MFS 커패시터의 게이트 전극 변화에 따른 특성)

  • 정순원;김광호
    • Journal of the Korean Vacuum Society
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    • v.11 no.4
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    • pp.230-234
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    • 2002
  • Metal-ferroelectric-semiconductor(MFS) capacitors by using rapid thermal annealed $LiNbO_3$/Si structures were successfully fabricated and demonstrated nonvolatile memory operations of the MFS capacitors. The C-V characteristics of MFS capacitors showed a hysteresis loop due to the ferroelectric nature of the $LiNbO_3$thin film. The dielectric constant of the $LiNbO_3$film calculated from the capacitance in the accumulation region in the capacitance-voltage(C-V) curve was about 25. The gate leakage current density of MFS capacitor using a platinum electrode showed the least value of $1{\times}10^{-8}\textrm{A/cm}^2$ order at the electric field of 500 kV/cm. The minimum interface trap density around midgap was estimated to be about $10^{11}/cm^2$.eV. The typical measured remnant polarization(2Pr) value was about 1.2 $\mu\textrm{C/cm}^2$, in an applied electric field of $\pm$ 300 kv/cm. The ferroelectric capacitors showed no polarization degradation up to about $10^{10}$ switching cycles when subjected to symmetric bipolar voltage pulse in the 500 kHz.

A study on the effects of behavior intention and satisfaction by festival service quality (지역축제 서비스품질이 만족도와 행동의도에 미치는 영향 연구)

  • An, Tai-Gi
    • Journal of the Korea Convergence Society
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    • v.8 no.11
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    • pp.279-285
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    • 2017
  • This study was conducted based on the evaluation items of the Ministry of Culture, Sports and Tourism as an index. Based on the previous researches of various researchers, hypotheses were set up to survey the visitors who participated in the bamboo festival. As a result of the study, three factors of the festival service quality factors (hardware, promotion, guidance, and program) were studied through factor analysis. As a result of the study, it was confirmed that PR and. Also, the event program had a significant effect on the revisit inquiry of the festival at .446. The effect of festival satisfaction on repeat visits and recommendation results. Beta (${\beta}$) values were found to be correlated with return visit (.584) and recommendation (.651). We will present the factors that need to be maintained through the World Bamboo Expo and the Festival of Damyang, identify the visitors' needs to visit again, and suggest some suggestions for Daelim's tourism industry, the fourth industry and eco-industry.

Inhibitory Effects of Actinidia arguta on HIV-1 Reverse transcriptase, HIV-1 Protease and alpha-glucosidase in vitro and in silico (다래나무 추출물의 HIV-1 효소억제활성과 구조활성상관(QSAR)예측)

  • Yu, Young-Beob
    • The Korea Journal of Herbology
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    • v.21 no.4
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    • pp.115-121
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    • 2006
  • Objectives : For the purpose of developing new anti-HIV agents from natural sources, the extracts of Actinidia arguta were tested for their inhibitory effects on essential enzymes as the reverse transcriptase (RT), protease and ${\alpha}-\;glucosidase$. And we predicted inhibition activity of major compounds of Actinidia arguta using Quantitative Structure Activity Relationships (QSAR). Methods : In this assay the activity of HIV-1 reverse transcriptase is measured as the formation of a strand of copy-DNA (cDNA) using RNA as a template. The activity of HIV-1 protease is measured as the cleavage of an oligopeptide by HIV-1 protease. Results : In the anti-HIV-1 RT using Enzyme Linked Oligonucleotide Sorbent Assay (ELOSA) method, water extracts (100ug/ml) of stem and leaf showed strong activity of 93.9% and 91.9%, respectively. In the HIV-1 protease inhibition assay, aqueous stem extract inhibited the activity of the enzyme to cleave an oligopeptide, resembling one of the cleavage sites in the viral polyprotein which can only be processed by HIV-1 protease with 56.8%. In the ${\alpha}-glucosidase$ inhibition assay, aqueous stem extract showed activity of 73.1%. Conclusion : We found out this result, for these samples it is possible that the inhibition of the viral replication in vitro is due to the inhibition at least one of RT and ${\alpha}-glucosidase$. It would be of great interest to identify the compounds which are responsible for this inhibition, since all therapeutically useful agent up to date are RT, PR and ${\alpha}-glucosidase$ inhibitors.

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Electrical Properties and Stability of ZPCCD-Based Varistors with Sintering Time (소결시간에 따른 ZPCCD계 바리스터의 전기적 특성 및 안정성)

  • Nahm, Choon-Woo;Park, Jong-Ah;Yoo, Dea-Hoon;Suh, Hyoung-Kwon
    • Journal of the Korean Ceramic Society
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    • v.42 no.7 s.278
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    • pp.490-496
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    • 2005
  • The electrical properties and stability of the varistors composed of ZnO-Pr$_{6}$O$_{11}$-CoO-Cr$_{2}$O$_{3}$-Dy$_{2}$O$_{3}$ system were investigated with sintering time in the range of 1$\~$3 h at 1350$^{\circ}C$ . As the sintering time was increased, the varistor voltage and leakage current increased, but the nonlinear exponent decreased. The varistors sintered for 1 h exhibited excellent nonlinearity, with a nonlinear exponent of 55.3 and a leakage current of 0.1 $\mu$A, whereas presented relatively low stability. The varistors sintered for 2 h exhibited not only high nonlinear exponent of 46.3, low leakage current of 0.3 $\mu$A, low dielectric dissipation factor of 0.0431, but also the highest stability, in which the variation rates of varistor voltage, nonlinear exponent, leakage current, dielectric constant, and dielectric dissipation factor were -3.0$\%$, -4.1$\%$, +3056.2$\%$, +5.1$\%$, and -12.5$\%$, respectively, after DC accelerated aging stress state of 0.95 V$_{1ma}$/150$^{\circ}C$/24 h. On the whole, the nonlinearity and stability of these varistors are greatly affected by the sintering time.

Comparative study of application method of OSMU(One-source Multi-use) in digital contents creation (디지털 영상콘텐츠의 원소스 멀티유스(One-Source Multi-Use) 제작방식 비교 연구)

  • Choi, Jeung-Il
    • Journal of Digital Contents Society
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    • v.9 no.4
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    • pp.551-560
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    • 2008
  • The basic strategy of OSMU(One-source Multi-use) in digital image is a marketing that applying one source to other genres for leverage based on that cross-referencing in different genre enabled that one material(one-source) has synergy effect when reproduced to various products(multi-use) as cultural sources are available through on-line and digital format. Recently, according to the characteristics of culture industry with Window Effect, many culture contents such as movies, games, animations and characters are carefully planned at its design stage to get the maximum effect. Especially, the fact that one leading-trend source makes it easier to produce additional products with the least cost is observed and it enables organized management which resulted in low marketing and PR cost. This paper confirmed that OSMU strategy in Korea mainly get started from online to offline comparing to Japan and USA.

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A FLOW AND PRESSURE DISTRIBUTION OF APR+ REACTOR UNDER THE 4-PUMP RUNNING CONDITIONS WITH A BALANCED FLOW RATE

  • Euh, D.J.;Kim, K.H.;Youn, Y.J.;Bae, J.H.;Chu, I.C.;Kim, J.T.;Kang, H.S.;Choi, H.S.;Lee, S.T.;Kwon, T.S.
    • Nuclear Engineering and Technology
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    • v.44 no.7
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    • pp.735-744
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    • 2012
  • In order to quantify the flow distribution characteristics of APR+ reactor, a test was performed on a test facility, ACOP ($\underline{A}$PR+ $\underline{C}$ore Flow & $\underline{P}$ressure Test Facility), having a length scale of 1/5 referring to the prototype plant. The major parameters are core inlet flow and outlet pressure distribution and sectional pressure drops along the major flow path inside reactor vessel. To preserve the flow characteristics of prototype plant, the test facility was designed based on a preservation of major flow path geometry. An Euler number is considered as primary dimensionless parameter, which is conserved with a 1/40.9 of Reynolds number scaling ratio. ACOP simplifies each fuel assembly into a hydraulic simulator having the same axial flow resistance and lateral cross flow characteristics. In order to supply boundary condition to estimate thermal margins of the reactor, the distribution of inlet core flow and core exit pressure were measured in each of 257 fuel assembly simulators. In total, 584 points of static pressure and differential pressures were measured with a limited number of differential pressure transmitters by developing a sequential operation system of valves. In the current study, reactor flow characteristics under the balanced four-cold leg flow conditions at each of the cold legs were quantified, which is a part of the test matrix composing the APR+ flow distribution test program. The final identification of the reactor flow distribution was obtained by ensemble averaging 15 independent test data. The details of the design of the test facility, experiment, and data analysis are included in the current paper.

A Grounded Approach to Dietary Experiences in College Women (여대생의 다이어트 경험에 관한 근거이론적 접근)

  • Lee, Jeong-Seop;Kim, Byoung-Hee;Jeong, Hyeon-Cheol;Lee, Seoung-Eun
    • Women's Health Nursing
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    • v.7 no.4
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    • pp.596-609
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    • 2001
  • This research is intended to study the dietary experiences by college women to promote women's health through the proper diet. The approach method was used grounded theory. The participants were selected 3 colleges in Seoul, Inchon, and Cheongju. The selected 15 women were college students who had a history of dietary experiences or who were on the way of diet at the time of the start of this research. The data were collected from August 2001 to October 2001. Data collecting method was a Focus Group Interview. The data were analysed by the Strauss and Corbin's method(1966). The results were showed that the 236 concepts in the dietary experiences were gathered into 48 sub-categories, eventually being integrated into 17 higher categories. 'Esthetic self-pursuit' is the core phenomenon of the dietary experiences. Such phenomenon is due to subjects physical problems, sense of comparison and desire of weight-loss. In the circumstantial context, the esthetic self-pursuit phenomenon is enhanced by social opinions, aesthetic senses, and the recognition of self-control. The interaction strategy of the esthetic self-pursuit can be intensified and sustained by will power, supporting systems, and accessibility. Through the dietary experiences, the body changes positive or negative figures. Following the sense of success or failure, the diet are sustained or abandoned accordingly. Therefore for the application of promoting health, an intervention strategy should be created a collect organized diet program in a social level not a private level.

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Disease Free Survival among Molecular Subtypes of Early Stage Breast Cancer between 2001 and 2010 in Iran

  • Najafi, Behrouz;Anvari, Saeid;Roshan, Zahra Atrkar
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5811-5816
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    • 2013
  • Background: Breast cancer is the most common cancer among women. Molecular subtypes are important in determining prognosis. This study evaluated five-year disease-free survival among four molecular subtypes in patients with early stages of breast cancer. Materials and Methods: In this retrospective descriptive-analytical study, information on patients with breast cancer between 2001-2010 was evaluated. Five hundred ninety two patients in the early stages of breast cancer (stages 1 and 2) were selected to undergo anthracycline-based chemotherapy. Relapse, death or absence (censor) were considered as the end of the study. Patients based on ER, PR and HER-2 expression were divided into four subtypes (luminal A, luminal B, HER-2 enriched and triple negative). Information based upon questionnaire was analysed. To show the patients survival rate, life table and Kaplan-Meyer methods were used, and for comparing mean survival among different groups, the Log-Rank test was utilized. Results: Mean age at diagnosis was $47.9{\pm}9.6$. Out of the 592 patients, 586 were female (99%) and 6 were male (1%). Considering breast cancer molecular subtypes, 361 patients were in the luminal A group (61%), 49 patients in the luminal B group (8.3%), 48 patients in the HER-2 enriched group (8.1%) and 134 in the triple negative group (22.6%). Mean disease-free survival was 53.7 months overall, 55.4 months for the luminal A group, 48.3 months for the luminal B group, 43 months for the HER-2enriched group and 54.6 months for the triple negatives. Disease free survival differed significantly among the molecular subtypes (p value=0.0001). Conclusions: The best disease-free survival rate was among the luminal A subgroup and the worst disease-free survival rate was among the HER-2 enriched subgroup. Disease free survival rate in the HER-2 positive groups (luminal B and HER-2 enriched) was worse than the HER-2 negative groups (luminal A and triple negative).