• Title/Summary/Keyword: Asymptotes

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The Effect of Histamine on the Disappearance Rate of $D_2O$ from the Arterial Blood of Rabbits (토끼 동맥혈로 부터의 $D_2O$ 소실률에 대한 히스타민의 영향)

  • Kim, Kyong-Tai;Shin, Dong-Hoon
    • The Korean Journal of Physiology
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    • v.1 no.1
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    • pp.23-32
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    • 1967
  • Disappearance rate of injected $D_2O$ from the arterial blood as well as the effect of histamine on the rate were studied in rabbits. The concentrations of $D_2O$ in the serial arterial samples obtained through a Polyethylene tubing inserted into the carotid artery were assayed by the freezing point elevation method of Reaser. At zero time 3 ml of isotonic $D_2O$ in normal saline was injected into the jugular vein and at the same time serial sampling of arterial blood started. The serial sampling interval was either 7.7 sec or 12.3 sec. In the histamine treated animals histamine diphosphate (0,5 mg of histamine base) was injected intravenously 30 minutes prior to the zero time. The following results were obtained. 1. $D_2O$ concentration in arterial plasma water, x, was empirically obtained by the sum of 2 exponential terms of time, $x=Ae^{-k1t}+Be^{-k2t},$ and its theoretical basis was sought. The first term of the right member of the equation was regarded to be attributable to the compartment P which possessed instantaneous exchange of water with plasma. The second term was postulated to represent the poorly exchangeable compartment. 2. The constant A of the equation was evaluated as 4,37% and 14.3% in the control and histamine treated groups, respectively. B was 1.19% in the control and 0.849% in histamine treated animals. 3. The disappearance rates determined were; $k_1=0.0519{\pm}0.0221\;sec^{-1}\;K_2=0.00454{\pm}0.00247\;sec^{-1}$ in the control group. $k_1=0.1137{\pm}0.0290\;sec^{-1}\;K_2=0.00499{\pm}0.00204\;sec^{-1}$ in the histamine group. 4. In the histamine treated animals the disappearance rate of the first term was larger than that of the control animals, suggesting an enlarged size of the rapidly exchangeable compartment with regard to the plasma water. On the other hand the constant B was decreased by histamine administration, suggesting a distribution of $D_2O$ in an enlarged volume. This view was also made clear by comparing the apparent asymptotes to which the concentration curves of $D_2O$ approached in respective groups. The asymptotes in the histamine treated group showed lower values.

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COSMIC RAY ACCELERATION AT COSMOLOGICAL SHOCKS

  • KANG HYESUNG;JONES T. W.
    • Journal of The Korean Astronomical Society
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    • v.37 no.5
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    • pp.405-412
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    • 2004
  • Cosmological shocks form as an inevitable consequence of gravitational collapse during the large scale structure formation and cosmic-rays (CRs) are known to be accelerated at collisionless shocks via diffusive shock acceleration (DSA). We have calculated the evolution of CR modified shocks for a wide range of shock Mach numbers and shock speeds through numerical simulations of DSA in 1D quasi-parallel plane shocks. The simulations include thermal leakage injection of seed CRs, as well as pre-existing, upstream CR populations. Bohm-like diffusion is assumed. We show that CR modified shocks evolve to time-asymptotic states by the time injected particles are accelerated to moderately relativistic energies (p/mc $\ge$ 1), and that two shocks with the same Mach number, but with different shock speeds, evolve qualitatively similarly when the results are presented in terms of a characteristic diffusion length and diffusion time. We find that $10^{-4} - 10^{-3}$ of the particles passed through the shock are accelerated to form the CR population, and the injection rate is higher for shocks with higher Mach number. The CR acceleration efficiency increases with shock Mach number, but it asymptotes to ${\~}50\%$ in high Mach number shocks, regardless of the injection rate and upstream CR pressure. On the other hand, in moderate strength shocks ($M_s {\le} 5$), the pre-existing CRs increase the overall CR energy. We conclude that the CR acceleration at cosmological shocks is efficient enough to lead to significant nonlinear modifications to the shock structures.

Numerical characterizations of a piezoelectric micromotor using topology optimization design

  • Olyaie, M. Sadeghbeigi;Razfar, M.R.
    • Smart Structures and Systems
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    • v.11 no.3
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    • pp.241-259
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    • 2013
  • This paper presents the optimum load-speed diagram evaluation for a linear micromotor, including multitude cantilever piezoelectric bimorphs, briefly. Each microbeam in the mechanism can be actuated in both axial and flexural modes simultaneously. For this design, we consider quasi-static and linear conditions, and a relatively new numerical method called the smoothed finite element method (S-FEM) is introduced here. For this purpose, after finding an optimum volume fraction for piezoelectric layers through a standard numerical method such as quadratic finite element method, the relevant load-speed curves of the optimized micromotor are examined and compared by deterministic topology optimization (DTO) design. In this regard, to avoid the overly stiff behavior in FEM modeling, a numerical method known as the cell-based smoothed finite element method (CS-FEM, as a branch of S-FEM) is applied for our DTO problem. The topology optimization procedure to find the optimal design is implemented using a solid isotropic material with a penalization (SIMP) approximation and a method of moving asymptotes (MMA) optimizer. Because of the higher efficiency and accuracy of S-FEMs with respect to standard FEMs, the main micromotor characteristics of our final DTO design using a softer CS-FEM are substantially improved.

Evaluation of three-dimensional cole-cole parameters from spectral IP data

  • Yang Jeong-Seok;Kim Hee Joon
    • 한국지구물리탐사학회:학술대회논문집
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    • 2003.11a
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    • pp.383-389
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    • 2003
  • Clay minerals show a distinct induced-polarization phenomenon, which is one of the most important factors for predicting groundwater flow and contaminant transport. This paper presents a step-by-step process to estimate Cole-Cole parameters from spectral induced-polarization (IP) data measured on the surface of three-dimensional earth. First, the inversion of low-frequency resistivity survey data is made to identify the dc resistivity ${\rho}_dc$ of a volume having IP effects. The other parameters, chargeability m, time constant $\tau$, and frequency dependence c, are sought for the polarizable volume. Next, using multi-frequency data, c can be obtained as high or low asymptotes of the slope of log phase vs. log frequency. Further, for low m, intrinsic $\tau$ is approximated by apparent one, ${\tau}_a$, which is derived from the relation ${{\omega}{\tau}}_a$=1 at an angular frequency $\omega$, where the imaginary component of spectral IP data has an extreme value. Finally, to obtain intrinsic m a two-step linearized procedure has been derived. For a body of given $\tau$ and c, forward modeling with a progression of m values yields a plot of observed vs. intrinsic imaginary components for a frequency. Since this plot is essentially linear, to extract the intrinsic imaginary component is quite simple with an observed value. Using the plot of intrinsic imaginary component vs. m, intrinsic m is determined. We present a synthetic example to illustrate that the Cole-Cole parameters can be recovered from spectral IP data.

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MYLLER CONFIGURATIONS IN FINSLER SPACES. APPLICATIONS TO THE STUDY OF SUBSPACES AND OF TORSE FORMING VECTOR FIELDS

  • Constantinescu, Oana
    • Journal of the Korean Mathematical Society
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    • v.45 no.5
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    • pp.1443-1482
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    • 2008
  • In this paper we define a Myller configuration in a Finsler space and use some special configurations to obtain results about Finsler subspaces. Let $F^{n}$ = (M,F) be a Finsler space, with M a real, differentiable manifold of dimension n. Using the pull back bundle $({\pi}^{*}TM,\tilde{\pi},\widetilde{TM})$ of the tangent bundle $(TM,{\pi},M)$ by the mapping $\tilde{\pi}={\pi}/TM$ and the Cartan Finsler connection of a Finsler space, we obtain an orthonormal frame of sections of ${\pi}^{*}TM$ along a regular curve in $\widetilde{TM}$ and a system of invariants, geometrically associated to the Myller configuration. The fundamental equations are written in a very simple form and we prove a fundamental theorem. Important lines in a Finsler subspace are defined like special lines in a Myller configuration, geometrically associated to the subspace: auto parallels, lines of curvature, asymptotes. Torse forming vector fields with respect to the Cartan Finsler connection are characterized by means of the invariants of the Frenet frame of a versor field along a curve, and the new notion of torse forming vector fields in the sense of Myller is introduced. The particular cases of concurrence and parallelism in the sense of Myller are completely studied, for vector fields from the distribution $T^m$ of the Myller configuration and also from the normal distribution $T^p$.

Topology Optimization for Large-displacement Compliant Mechanisms Using Element Free Galerkin Method

  • Du, Yixian;Chen, Liping
    • International Journal of CAD/CAM
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    • v.8 no.1
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    • pp.1-10
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    • 2009
  • This paper presents a topology optimization approach using element-free Galerkin method (EFGM) for the optimal design of compliant mechanisms with geometrically non-linearity. Meshless method has an advantage over the finite element method(FEM) because it is more capable of handling large deformation resulted from geometrical nonlinearity. Therefore, in this paper, EFGM is employed to discretize the governing equations and the bulk density field. The sensitivity analysis of the optimization problem is performed by incorporating the adjoint approach with the meshless method. The Lagrange multipliers method adjusted for imposition of both the concentrated and continuous essential boundary conditions in the EFGM is proposed in details. The optimization mathematical formulation is developed to convert the multi-criteria problem to an equivalent single-objective problem. The popularly applied interpolation scheme, solid isotropic material with penalization (SIMP), is used to indicate the dependence of material property upon on pseudo densities discretized to the integration points. A well studied numerical example has been applied to demonstrate the proposed approach works very well and the non-linear EFGM can obtain the better topologies than the linear EFGM to design large-displacement compliant mechanisms.

The SIMP-SRV Method for Stiffness Topology Optimization of Continuum Structures

  • Zhou, Xiangyang;Chen, Liping;Huang, Zhengdong
    • International Journal of CAD/CAM
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    • v.7 no.1
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    • pp.41-49
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    • 2007
  • In density-based topology optimization, 0/1 solutions are sought. Discrete topological problems are often relaxed with continuous design variables so that they can be solved using continuous mathematical programming. Although the relaxed methods are practical, grey areas appear in the optimum topologies. SIMP (Solid Isotropic Microstructures with Penalization) employs penalty schemes to suppress the intermediate densities. SRV (the Sum of the Reciprocal Variables) drives the solution to a 0/1 layout with the SRV constraint. However, both methods cannot effectively remove all the grey areas. SRV has some numerical aspects. In this work, a new scheme SIMP-SRV is proposed by combining SIMP and SRV approaches, where SIMP is employed to generate an intermediate solution to initialize the design variables and SRV is then adopted to produce the final design. The new method turned out to be very effective in conjunction with the method of moving asymptotes (MMA) when using for the stiffness topology optimization of continuum structures for minimum compliance. The numerical examples show that the hybrid technique can effectively remove all grey areas and generate stiffer optimal designs characterized with a sharper boundary in contrast to SIMP and SRV.

DETAILED EXAMINATION OF INVERSE-ANALYSIS PARAMETERS FOR PARTICLE TRAPPING IN SINGLE CHANNEL DIESEL PARTICULATE FILTER

  • Jung, S.C.;Park, J.S.;Yoon, W.S.
    • International Journal of Automotive Technology
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    • v.8 no.2
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    • pp.165-177
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    • 2007
  • Predictions of diesel particulate filtration are typically made by modeling of a particle collection, and providing particle trapping levels in terms of a pressure drop. In the present study, a series of single channel diesel particulate filter (DPF) experiments are conducted, the pressure traces are inversely analyzed and essential filtration parameters are deducted for model closure. A DPF filtration model is formulated with a non-linear description of soot cake regression. Dependence of soot cake porosity, packing density, permeability, and soot density in filter walls on convective-diffusive particle transportation is examined. Sensitivity analysis was conducted on model parameters, relevant to the mode of transition. Soot cake porosity and soot packing density show low degrees of dispersion with respect to the Peclet number and have asymptotes at 0.97 and $70\;kg/m^3$, respectively, at high Peclet number. Soot density in the filter wall, which is inversely proportional to filter wall Peclet number, controls the filtration mode transition but exerts no influence on termination pressure drop. The percolation constant greatly alters the extent of pressure drop, but is insensitive to volumetric flow rate or temperature of exhaust gas at fixed operation mode.

Topology optimization with functionally graded multi-material for elastic buckling criteria

  • Minh-Ngoc Nguyen;Dongkyu Lee;Joowon Kang;Soomi Shin
    • Steel and Composite Structures
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    • v.46 no.1
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    • pp.33-51
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    • 2023
  • This research presents a multi-material topology optimization for functionally graded material (FGM) and nonFGM with elastic buckling criteria. The elastic buckling based multi-material topology optimization of functionally graded steels (FGSs) uses a Jacobi scheme and a Method of Moving Asymptotes (MMA) as an expansion to revise the design variables shown first. Moreover, mathematical expressions for modified interpolation materials in the buckling framework are also described in detail. A Solid Isotropic Material with Penalization (SIMP) as well as a modified penalizing material model is utilized. Based on this investigation on the buckling constraint with homogenization material properties, this method for determining optimal shape is presented under buckling constraint parameters with non-homogenization material properties. For optimal problems, minimizing structural compliance like as an objective function is related to a given material volume and a buckling load factor. In this study, conflicts between structural stiffness and stability which cause an unfavorable effect on the performance of existing optimization procedures are reduced. A few structural design features illustrate the effectiveness and adjustability of an approach and provide some ideas for further expansions.

Optimal Design of the Tractrix Die Used in the DDI Process for Manufacturing CG Pressure Vessels (CNG 압력용기 제작을 위한 D.D.I. 공정의 Tractrix 다이 최적설계)

  • Lee, Kwang O;Sim, Hyeon Dae;Kwak, Hyo seo;Kim, Chul
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.10
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    • pp.879-886
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    • 2016
  • Tractrix dies, used in the deep drawing process, can be used to form CNG pressure vessels without a blank holder. Previous studies had only applied tractrix profiles to perform the first deep drawing process of DDI; but an optimal design of the tractrix die that focuses on improving die life and reducing production cost has not been performed yet. In this study, finite element analyses of deep drawing processes were conducted according to heights of the tractrix die by using translating asymptotes. In addition, researchers analyzed von-Mises stresses at the part of stress concentration of the die according to the forming punch loads in order to propose an optimal tractrix die design.