• 한국식품영양과학회지
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• 제31권1호
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• pp.149-154
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• 2002

본 연구의 목적은 생약제 및 양파 혼합물의 급여가 비육돈의 성장 및 도체 특성에 미치는 영향을 평가하기 위하여 실시하였다. 3원 교잡종(Durox$\times$Yorkshire$\times$Landrace) 비육돈 72두을 공시하였으며 시험개시시의 체중은 체중은 75.66$\pm$1.86 kg 이었다. 처리구로는 옥수수-대두박 위주의 식이에 NRC(12)의 영양소 요구량에 따라 처리한 구(Control: 기초식이), 대조구 식이내 생약제 및 양파 혼합물을 0.25% 첨가한 구(AGO 0.25: 기초식이+0.25% 생약제 및 양파 혼합물), 대조구 식이내 생약제 및 양파 혼합물을 0.50% 첨가한 구(AGO 0.50: 기초식이 + 0.50% 생약제 및 양파 혼합물)로 3개 처리를 하여 처리당 4반복, 반복당 6마리씩 완전임의 배치하였다. 본 사양시험에 사용한 생약제 및 양파 혼합물은 인삼, 황기 그리고 양파 분말을 함유한 것을 사용하였다. 전체 시험기간 동안, 생약제 및 양파 혼합물의 첨가수준이 증가함에 따라 식이효율 및 등지방 두께가 증가하는 경향을 나타내었으나 유의적인 차이는 보이지 않았다(p>0.05). 도체등급에 있어서는 생약제 및 양파 혼합물의 첨가수준이 증가함에 따라 A등급 출현율이 높은 것으로 평가되었다(linear effect, p<0.01). 대조구 및 AGO 0.50 처리구와 비교하여 AGO 0.25 처리구가 혈청내 총 콜레스테롤 및 LDL+VLDL 콜레스테롤 농도가 낮은 것으로 평가되었으나 유의적인 차이는 보이지 않았다(p>0.05). 도축한 돈육의 등심부의 육색에 있어서 L-$^{*}$ , a-$^{*}$ , b-$^{*}$ 값에 있어서도 유의적인 차이를 보이지 않았다(p>0.05). 생약제 및 양파 혼합물 급여에 따른 증체량 개선 효과로 인해 증체당 식이비는 대조구가 830원, AGO 0.50 처리구가 813원으로 대조구와 비교하여 2.05%의 식이비 절감 효과를 나타내었다. 결론적으로 비육돈 식이내 생약제 및 양파 혼합물의 첨가가 성장 촉진을 갖는 것으로 사료되나 도체특성에는 영향을 미치지 않는 것으로 판단된다.

• Preventive Nutrition and Food Science
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• 제7권3호
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• pp.323-326
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• 2002

Ionizing radiation can be used to sanitize herbs contaminated by various microorganisms. However, health concerns related to irradiation damage to complex molecules in plants necessitate that methods be developed to monitor such damage. To elucidate DNA damage of herbs caused by irradiation, the DNA comet assay was used for Astragalus membranaceus Bunge and Havenia dulcis Thumb, irradiated at 1, 5, 7, and 10 kGy. With increasing irradiation doses, the tails of comets became longer with average tail length increasing from 17 (non-irradiated) to 124 (10 kGy) $\mu$m in Astragalus membranaceus Bunge. Above 7 kGy, some of the tails were separated from the heads of comets. Distribution patterns of the tail length of In comets selected randomly in the irradiated herbs were analyzed to quantify the DNA damage. These results clearly suggest that the DNA comet assay is an effective and inexpensive tool for the detection of irradiation damage to DNA in herbs.

• Natural Product Sciences
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• 제14권2호
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• pp.131-137
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• 2008

From the 70% EtOH extract of the roots of Astragalus membranaceus (Leguminosae), eleven flavonoid derivatives and a lignan, were isolated and identified as liquiritigenin (1), daidzein (2), formononetin (3), sophorophenolone (4), calycosin (5), methylnissolin (6), isomucronulatol (7), isomucronulatol 7-O-glucoside (8), methylnissolin 3-O-glucoside (9), calycosin 7-O-glucoside (10), (+)-syringaresinol O-${\beta}$-D-glucoside (11), and isomucronulatol 7,2'-di-O-glucoside (12), by spectroscopic methods. This is the second report of the isoflavonoid derivatives sophorophenolone (4) and isomucronulatol 7,2'-di-O-glucoside (12) from a natural source, as well as the first report of compounds liquiritigenin (1), daidzein (2) and (+)-syringaresinol O-${\beta}$-D-glucoside (11) from the species A. membranaceus.

• Journal of Applied Biological Chemistry
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• 제49권4호
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• pp.176-179
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• 2006

Electron beam irradiation was applied to examine the microbial growth and qualities of vacuum-packaged Astragalus membranaceus, a Korean medicinal herb. Samples were irradiated at dose of 2, 4, 8, 12, and 16 kGy, respectively. Microbiological data on A. membranaceus showed that populations of total bacteria, yeast and mold, total coliforms were significantly reduced with increase of irradiation dose. Populations of microorganisms in A. membranaceus were decreased by 2-3 log cycles at 8 kGy irradiation. Color measurements showed that electron beam treatment caused negligible changes in Hunter color L, a, and b values of A. membranaceus. Sensory evaluations showed that there were no significant changes among the samples. These results suggest that electron beam irradiated A. membranaceus have better microbial safety and qualities, compared with the non-irradiated control.

• 생약학회지
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• 제27권2호
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• pp.111-116
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• 1996

The components were isolated from the root of Astragalus membranaceus and their structures were characterized as 3,4-methylenedioxypyrrolealdehyde, $7-O-{\beta}-D-glucopyranosyl$ 7, 3'-dihydroxy-4'-methoxy isoflavone and a naphthalene derivative on the basis of spectral and physical methods. $7-O-{\beta}-D-glucopyranosyl$ 7, 3'-dihydroxy-4'-methoxy isoflavone and the naphthalene compound showed protective effect on $CC_{l4}-induced$ cytotoxicity in primary cultured rat hepatocytes.

• Advances in Traditional Medicine
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• 제7권5호
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• pp.569-572
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• 2008

The root of Astragalus membranaceous (AM) has been used to treat edema and arthritis in the traditional Korean medicine. To elucidate the anti-inflammatory and anti-nociceptive effects of ethanol extract of AM, the carrageenan-induced paw edema using a plethysmometer and thermal hypersensitivity using the plantar test were measured. Ibuprofen was used as a control drug. Pretreatment with AM (400 mg/kg p.o.) significantly reduced paw edema, compared to the carrageenan-treated rats. In the plantar test, the thermal withdrawal latency in AM-treated group was significantly increased than the carrageenan-treated group. The results indicate that AM could have be the anti-inflammatory and anti-nociceptive properties.

• 한국약용작물학회지
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• 제22권2호
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• pp.91-97
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• 2014

The contents of index components in 5 medicinal crops cultivated at different heights in Andong area. The contents of allantoin in Dioscorea batatas Decne and catalpol in Rehmannia glutinosa Liboschitz were not different by cultivation heights (100 ~ 200m). But the contents of index components in Astragalus membranaceus and Angelica acutiloba Kitagawa were higher in samples cultivated at elevated heights. At 700 m of heights, the contents of formononetin and astragaloside I in Astragalus membranaceus were 1.20 and $201.2{\mu}g/g$, respectively. The contents of decursin and nodakenin in Angelica acutiloba Kitagawa were 68.3 and 4.20 mg/g, respectively. Thus Astragalus membranaceus and Angelica acutiloba Kitagawa are recommended to be cultivated in higher altitude.

• 대한화학회지
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• 제7권3호
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• pp.207-210
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• 1963

"Astragalus Membranaceus Bunge", which is a medical herb, grows wild in Manchuria and Korea, is cultivated today in Korea. Any literature about the organic components of "Astragalus Membranaceus Bunge" has been extracted with methanol referring to a literature of "Panax Ginseng C.A. Meyer" and two kinds of colorless crystals were obtained. After recrystallization in absolute alcohol, the melting point has been measured. The one kind was $181-182^{\circ}C$ and the others, $184-186{\circ}C$ respectively. It does not contain nitrogen, sulfur and halogen. By Liebermann's reaction, the one kind was not a carbohydrate but might be a Saponin. Through paper chromatography, taste, melting point, spectrophotometry, and elemental analysis, it was concluded that the other was Sucrose. It has been notified that the compound can be crystallized at the proper temperature, purity, and concentration of the solution and also solvent system.

• Journal of Plant Biology
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• 제24권1호
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• pp.27-30
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• 1981

한국의 신분류군 식물에 대하여 3신종, 2변종과 1품종을 다음과 같이 발표하는 바이다. Astragalus koraiensis Y. Lee 정선황기 ; A. nakaianus Y. Lee 제주황기; Commelina minor Y. Lee & Oh Y. 애기닭의장풀: Cirsium rhinoceros Nakai var. albiflorum Y. Lee 흰바늘엉겅퀴 ; Tripterospermum japonicum (Sieb. & Zucc.) Max. va. albiflorum Y, Lee 흰덩굴용담 Adenophora remotiflora (Sieb. & Zucc.) Maq. form. albiflora Y. Lee 흰모시대.

• 약학회지
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• 제49권1호
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• pp.11-19
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• 2005

The root of Astragalus membranaceus (Leguminosae) has been used in traditional chinese prescriptions for strengthning the superficial resistance, promoting pus discharge and tissue regeneration, diuretis and alleviating edema. Lipid peroxidation has been suggested as a major cause of atherosclerosis, cancer, liver disease, and the aging process. In order to investigate the anti-lipid peroxidation activity, Astragali Radix was extracted with $80\%$ MeOH and fractionated with hexane, $CH_{2}Cl_2$, EtOAc, BuOH and Water. The antilipid peroxidation activities of them were determined by human erythrocyte ghost and $CCl_4$-induced lipid peroxidation. $CH_{2}Cl_2$ and EtOAc fractions, especially, isoflavonoids, 7,2'-dihydroxy-3',4'-dimethoxyisoflavan-7-O-${\beta}$-D-glucoside and calyco sin-7-O-${\beta}$-D-glucoside from EtOAc fraction showed anti-lipid peroxidation activities.