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Phytochemical Studies on Astragalus Root (2);Flavonoids and a Lignan  

Lee, Eun-Ju (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Yean, Min-Hye (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Jung, Hye-Sil (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kim, Ju-Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kang, Sam-Sik (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Publication Information
Natural Product Sciences / v.14, no.2, 2008 , pp. 131-137 More about this Journal
Abstract
From the 70% EtOH extract of the roots of Astragalus membranaceus (Leguminosae), eleven flavonoid derivatives and a lignan, were isolated and identified as liquiritigenin (1), daidzein (2), formononetin (3), sophorophenolone (4), calycosin (5), methylnissolin (6), isomucronulatol (7), isomucronulatol 7-O-glucoside (8), methylnissolin 3-O-glucoside (9), calycosin 7-O-glucoside (10), (+)-syringaresinol O-${\beta}$-D-glucoside (11), and isomucronulatol 7,2'-di-O-glucoside (12), by spectroscopic methods. This is the second report of the isoflavonoid derivatives sophorophenolone (4) and isomucronulatol 7,2'-di-O-glucoside (12) from a natural source, as well as the first report of compounds liquiritigenin (1), daidzein (2) and (+)-syringaresinol O-${\beta}$-D-glucoside (11) from the species A. membranaceus.
Keywords
Astragalus membranaceus; Leguminosae; flavonoid; lignan;
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Times Cited By KSCI : 6  (Citation Analysis)
Times Cited By SCOPUS : 3
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