• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1997년도 춘계학술발표회논문집(2)
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• pp.515-519
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• 1997

The purpose of this study is to reduce the fast neutron fluence at the reactor pressure vessel(RPV) and to provide a basis for plant-life extension. In this study, different neutron absorbers were employed in the core outer assemblies of Kori Unit 1 Cycle 14. The modified assemblies were used to calculate fast neutron fluence at the RPV and to evaluate reduction of outer assembly power and total power in core. By comparison with the case of no suppression fixture, the fast neutron fluence of a case with two rows stainless steel around the assembly with natural uranium pins is decreased by 85.8%. It is noted that the modification of outer assembly is more efficient than the previous low leakage loading pattern (LLLP) applied to Kori Unit 1. Also, compared fast neutron fluence in Cycle 1 with Cycle 14, fast neutron fluence at the RPV between Cycle 1 and Cycle 14 is not significantly different. It is found that LLLP applied to the Kori Unit 1 has not contributed to fast neutron fluence reduction at the RPV.

• 대한인간공학회지
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• 제24권2호
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• pp.57-63
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• 2005

Ergonomic intervention techniques were adopted to assess and control potential risk factors of work-related musculoskeletal disorders(WMSDs) in the automated light assembly manufacturing system. Ten different kinds of assembly workstations implemented with a conveyor system and twelve female workers were observed and evaluated with careful video film analysis. Several close examinations using sets of checklists established by qualified safety and health organizations, such as NIOSH, OSHA, and ANSI, were conducted and every workers and staffs in the site participated in the self-report questionnaires and off-line interviews. Typical risk factors and symptoms of the upper extremity musculoskeletal disorders were found and categorized into specific parts of body. To reduce risk factors of WMSDs and improve system productivity new revised workstation standards, physical dimensions, were suggested accordant with anthropometric characteristics of workers and a heuristic decision strategy of rotating shift work schedules according to work contents has proposed to mitigate cumulative physical stress. Finally, ergonomic programs of entire company to prevent WMSDs were structured.

• 품질경영학회지
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• 제38권3호
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• pp.439-448
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• 2010

Since the six sigma strategy was first introduced to Motorola in 1987, it has been taken as an important business strategy to strengthen the competitiveness of leading companies in the global competitiveness environm ent. This paper presents a six sigma project to reduce the cycle time of assembly line in a medium size automotive part company. The project follows a structured methodology of DMAIC cycle which consists of Define, Measure, Analyze, Improve, and Control. A CTQ is determined based on COPQ analysis, and a process map is utilized for identifying process input variables. As a result of the project, two assembly lines are converted to cell line production lines. The cycle times become 55 sec./unit and 64 sec./unit from 64 sec./unit and 83 sec./unit at the beginning of the project, respectively.

• International Journal of Control, Automation, and Systems
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• 제3권3호
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• pp.461-468
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• 2005

This paper proposes a wheel-assembly automation system, which assembles a wheel into a hub of a vehicle hung to a moving hanger in a car manufacturing line. A macro-micro manipulator control strategy is introduced to increase the system bandwidth and tracking accuracy to ensure insertion tolerance. A camera is equipped at the newly designed wheel gripper, which is attached at the center of the end-effector of the macro-micro manipulator and is used to measure position error of the hub of the vehicle in real time. The redundancy problem in the macro-micro manipulator is solved without complicated calculation by assigning proper functions to each part so that the macro part tracks the velocity error while the micro part regulates the fine position error. Experimental results indicate that tracking error satisfies the insertion tolerance of assembly $({\pm}1mm)$, and thus it is verified that the proposed system can be applied to the wheel assembly task on a moving hanger in the manufacturing line.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.308-308
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• 2006

We have demonstrated that the cylindrical micelles self-assembled from coil-rod-coil molecules can be interconnected by addition of a small amount of rod-coil-rod molecule as a bridging agent. Subsequently, these dynamic interconnections lead to stiff bundles composed of cylindrical micelles that are responsible for the formation of a reversible nematic gel. The results described here represent a significant example that dynamic bridging of supramolecular cylinders in aqueous solution can provide a useful strategy to construct one-dimensional nematic structure with three dimensional elastic properties.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.248-248
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• 2006

The notable feature of the Cu(II) coordination polymer investigated here is its ability to self-assemble into a double-stranded helical structure with regular grooves along the helical axis, through the combination of metal-chloride dimeric interactions and repulsive interactions, as an organizing force. It is also remarkable that the double-stranded helices self-organize into a 2-D columnar structure in both the bulk state and aqueous solution. These results represent a unique example that weak metal-ligand bridging interactions can provide a useful strategy to construct stable double-stranded helical nanotubes.

• Structural Engineering and Mechanics
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• 제61권3호
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• pp.335-345
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• 2017

Free vibration analysis for continuous bridge under any number of vehicles is conducted in this paper. Calculation strategy for natural frequency and mode shape is proposed based on Euler-Bernoulli beam theory and numerical assembly method. Firstly, a half-car planar model is adopted; equations of motion and displacement functions for bridge and vehicle are established, respectively. Secondly, the undermined coefficient matrices for wheels, vehicles, intermediate support, left-end support and right-end support are derived. Then, the numerical assembly technique for conventional finite element method is adopted to construct the overall matrix of coefficients for whole system. Finally, natural frequencies and corresponding mode shapes are determined based on iterative method and overall matrix solution. Numerical simulation is presented to verify the effectiveness of the proposed method. The results reveal that the solutions of present method are exact ones. Natural frequencies and associate modal shapes of continuous bridge under different conditions of vehicles are investigated. The influences of vehicle parameters on natural frequencies are also demonstrated.

• 한국경영과학회지
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• 제37권3호
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• pp.39-55
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• 2012

This paper presents an endosymbiotic evolutionary algorithm (EEA) to solve both problems of line balancing and model sequencing in a mixed-model two-sided assembly line (MMtAL) simultaneously. It is important to have a proper balancing and model sequencing for an efficient operation of MMtAL. EEA imitates the natural evolution process of endosymbionts, which is an extension of existing symbiotic evolutionary algorithms. It provides a proper balance between parallel search with the separated individuals representing partial solutions and integrated search with endosymbionts representing entire solutions. The strategy of localized coevolution and the concept of steady-state genetic algorithms are used to improve the search efficiency. The experimental results reveal that EEA is better than two compared symbiotic evolutionary algorithms as well as a traditional genetic algorithm in solution quality.

• BMB Reports
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• 제49권9호
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• pp.459-473
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• 2016

Neurodegenerative diseases (NDs) often involve the formation of abnormal and toxic protein aggregates, which are thought to be the primary factor in ND occurrence and progression. Aged neurons exhibit marked increases in aggregated protein levels, which can lead to increased cell death in specific brain regions. As no specific drugs/therapies for treating the symptoms or/and progression of NDs are available, obtaining a complete understanding of the mechanism underlying the formation of protein aggregates is needed for designing a novel and efficient removal strategy. Intracellular proteolysis generally involves either the lysosomal or ubiquitin-proteasome system. In this review, we focus on the structure and assembly of the proteasome, proteasome-mediated protein degradation, and the multiple dynamic regulatory mechanisms governing proteasome activity. We also discuss the plausibility of the correlation between changes in proteasome activity and the occurrence of NDs.

• KSBB Journal
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• 제13권4호
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• pp.369-377
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• 1998

To analyze the unique aspects of biomolecular processing for monoclonal antibody (MAb) production and secretion, the simple working model based on 3-compartment (endoplasmic reticulum, Golgi apparatus, and extracellular medium) was developed. Based on in vitro MAb assembly experimental results, the kinetic model for MAb assembly in the endoplasmic reticulumn was proposed. The dynamics of MAb assembly and secretion was simulated using methematica program. According to the simulation results, the proposed 3-compartment model provides an efficient means to predict the specific MAb productivity as well as intracompartmental concentrations of MAb in endoplasmic reticulum, Golgi apparatus, and extracellular compartment model. In vivo profiles of MAb intermediates gave good agreements with the simulation profiles predicted by the intracellular compartment model. Furthermore, results of such analysis can help in directing the control strategy for optimum biomolecular processing in a mammalian cell culture system.