• Bulletin of the Korean Chemical Society
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• v.33 no.1
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• pp.149-152
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• 2012

The (S)-(+)-decursin and its analogues are reported as potent inhibitors of melanin production in B16 murine melanoma cells. In order to understand the factors responsible for potency as well as inhibition of potency of (S)-(+)-decursin and its analogues, three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed. Since receptor structures are not available, a pharmacophore model was constructed. Using PHASE, we generated 3 different models and selected the seven-site model, which returned excellent statistical values ($r^2$ = 0.9127, $Q^2$ = 0.6878, Pearson-R = 0.9014). Using the generated pharmacophore model, we screened a natural products library and obtained 4'-epi-decursin as the most related compound. 4'-epidecursin is similar to (S)-(+)-decursin, but shows additional interaction possibilities with tyrosinase. The study thus sheds some light on possibility of developing more potent tyrosinase inhibitors.

• Journal of the Korean Home Economics Association
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• v.34 no.2
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• pp.5-30
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• 1996

The purpose of this study is to observe artistic of Expressionism reflected to works of European costume designers by analizing works of seven major representative costume designers in the twentieth century. They are Mariano Fortuny, Paul poiret, Madelene Vionnet, Jean Patou, Jeanne Lanvin, Gabriel Chanel and Elsa Schiaparelli. These designers deployed individual and various creative costume design work with peculiar expresive techniques, which is based on the Expressionism. Although each creative work was made in extremely unique sense, there was comon expressive spirituality I their creative activity. The findings are as follows : 1. Based on the "Medieval-directed characteristic" which arose over all fields of art of those days, a modern and reformative clothing beauty was created by reanalyzing traditional motive. 2 Characteristic of Cubistic Expressionism were described in overall silhouette of clothing and fine decorative element. 3. Fantastic Expressionism, which pursued basic worth from the primitive and ethnic customs, effected costume style of early 20th century and draw such designers as Mariano Fortuny, Leon Bakst, Paul Poiet, Elsa Schiaqarelli to adopt intensive and primary color. And it also gave an impact against traditional concepts by accepting fantastic oriental Exoticism.Exoticism.

• Journal of The Korea Institute of Healthcare Architecture
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• v.13 no.3
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• pp.47-55
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• 2007

The theme of this study is holistic healing environment of children's library and it was researched on the basis of anthroposophy theory of Rudolf Steiner. According to Steiner's theory, human being consists of body, spirit, and soul. Especially, children are sensitive ones, and through synthetic function of 12 kinds of senses, they can be holistically healed (healing of body, spirit, and soul). As the sense independently functions or it is a element that cannot be described, it needs spatial plan to support synthetic function of it. We classified the healing space's meaning of children library by motion (including art and music), reading, & landscape healing activities and analyzed spatial characteristic to support each activity.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.63 no.4
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• pp.226-235
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• 2014

Nowadays, railroads are considered the most efficient form of mass transportation. Furthermore, it is necessary that railroads be paired with state-of-the-art safety equipment. Unfortunately, it is impossible to prevent 100% of accidents that may be caused by system or human errors. In order to prevent future accidents, RAMS activity and Functional Safety Certification are required for new systems that are under development. In this paper we evaluate the necessity of the application of RAMS and the performance of RAMS in the system development process. We also explore the Safety Evaluation Procedure required for RAMS certification.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.12 no.1
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• pp.11-20
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• 2002

The world at the end of the $20^{th}$ Century has become "blue" Indeed, this past decade has witnessed a "blue rush" towards the development of violet-blue-green light emitting diodes (LEDs) and laser diodes (LDs) based on wide bandgap III-Nitride semiconductors. And the hard work has culminated with, first, the demonstration of commercial high brightness blue and green LEDs and of commercial violet LDs, at the very end of this decade. Thanks to their extraordinary properties, these semiconductor materials have generated a plethora of activity in semiconductor science and technology. Novel approaches are explored daily to improve the current optoelectronics state-of-the-art. Such improvements will extend the usage and the efficiency of new light sources (e.g. white LEDs), support the rising information technology age (e.g. high density optical data storage), and enhance the environmental awareness capabilities of humans (ultraviolet and visible photon detectors and sensors). Such opportunities and many others will be reviewed in this presentation.

• Korean Journal of Child Studies
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• v.23 no.4
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• pp.137-152
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• 2002

In response to a growing trend toward downward escalation of public school curriculum, the present study surveyed so-called extracurricular activities in kindergartens and analyzed teacher's perception of these activities. Questionnaires were mailed to 1300 private kindergartens and 1116 responses were received. Major findings were that over 89% of the respondents reported doing extracurricular activities in their kindergartens, mostly using 3-4 different kinds of special activities. The 3 most highly ranked lessons in order of frequency were English, art and physical activity. Whole group time was most often used for extracurricular activities. Kindergarten teachers were concerned with the qualifications of teachers for these activities. Teachers of these extra activities usually have no specialized training or supervised experience working with 3-through 5-year-old children.

• Journal of Microbiology and Biotechnology
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• v.16 no.10
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• pp.1629-1633
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• 2006

Ginsenosides have been regarded as the principal components responsible for the pharmacological and biological activities of ginseng. The transformation of ginsenosides with live lactic acid bacteria transformed ginsenosides Rb2 and Rc into Rd, but the reactions were slow. When the crude enzymes obtained from several lactic acid bacteria were used for transformation, those from Bifidobacterium sp. Int57 exhibited the most potent transforming activity of ginsenosides to compound K. In comparison, a relatively higher level of Rh2 was produced by the enzymes from Lactobacillus delbrueckii and Leuconostoc mesenteroides. These results suggest that it is feasible to develop a specific bioconversion process to obtain specific ginsenosides using the appropriate combination of ginsenoside substrates and specific microbial enzymes.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.520-523
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• 2005

(R)-(-)-PGME amide of diterpene acid (2) was assigned the absolute configuration from NMR correlation experiments. The compound (2) was tested for its growth inhibitory effects against tumor cell lines by the MTT method.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.5
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• pp.2327-2347
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• 2018

Human actions can be recognized from depth sequences. In the proposed algorithm, we initially construct depth, motion maps (DMM) by projecting each depth frame onto three orthogonal Cartesian planes and add the motion energy for each view. The body part of the action (BPoA) is calculated by using bounding box with an optimal window size based on maximum spatial and temporal changes for each DMM. Furthermore, feature vector is constructed by using BPoA for each human action view. In this paper, we employed an ensemble based learning approach called Rotation Forest to recognize different actions Experimental results show that proposed method has significantly outperforms the state-of-the-art methods on Microsoft Research (MSR) Action 3D and MSR DailyActivity3D dataset.

• Journal of Korean Theatre Studies Association
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• no.49
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• pp.101-131
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• 2013

This paper reviews the Insaenggeukjang's history and Insaenggeukjang's play. This paper has been written with a purpose to understand and to examine the members(actors and actresses), the structure, the plays, the performing works, the change process, and the meaning of Insaenggeukjang(life theater) and junggangeug(middle-theater) in 1930s. Insaenggeukjang is Korean theater for the drama in the second half of 1930s. In particular, Insaenggeukjang is a theatrical troupe that led Korean theatrical troupes in 1937 to 1938. This paper intend to examine Insaenggeukjang's history, activity, feature and works. I study Insaenggeukjang and performing works contained in the newspapers and the magazines in 1920-30s, and conference papers and theater-art books published recently.