• 제목/요약/키워드: Angelica genus

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Acetylcholinesterase Inhibitors from Angelica polymorpha Stem

  • Kwon, Yongsoo;Kim, Hyun Pyo;Kim, Myong Jo;Chun, Wanjoo
    • Natural Product Sciences
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    • v.23 no.2
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    • pp.97-102
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    • 2017
  • Fourteen compounds were isolated from the stem of Angelica polymorpha. On the basis of spectral data, these compounds were identified as isoimperatorin (1), phellopterin (2), bergapten (3), xanthyletin (4), cnidilin (5), geijerine (6), (-)-3'-acetyl hamaudol (7), 7-demethylsuberosine (8), dehydrogeijerin (9), (-)-hamaudol (10), (+)-visamminol (11), divaricatol (12), scopoletin (13), and decursidate (14), respectively. Among them, compounds 4-6, 8, 9, 13, and 14 were isolated for the first time from A. polymorpha. Dehydrogeijerin (6) and geijerin (9) were isolated for the first time from genus Angelica. All isolates tested for inhibitory activity against acetylcholinesterae. Compounds 1 to 13 showed acetylcholinesterase inhibitory activity with $IC_{50}$ values ranging from 1.4 to $37.5{\mu}M$.

Cytotaxonomic Studies on the Umbelliferae Plants -Cytological Study on Some Species of Angelica- (미나리과 식물의 세포분류학적 연구 -Angelica 속 식물에 관하여-)

  • Toh, Chung-Ae
    • Korean Journal of Pharmacognosy
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    • v.1 no.1
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    • pp.19-24
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    • 1970
  • A comparative study on 'Dang-gui' and 'Kang-whal' the two species of Angelica growing in Korea was carried out about the morphology and cytology. The somatic chromosome number of Cham dang-gui, Ill dang-gui, Badi-namul was found to be 2N=22. The somatic chromosome number of Kang-whal was found to be 2N=110, that of Chili kang-whal to be 2N=44, that of Mul kang-whal to be 2N=22. Stoma of species of Dang-gui were same in size. Those of Chili kang-whal and Kang-whal were strikingly larger than the other. Chili kang-whal and Kang-whal were verified to be polyploid in the genus Angelica.

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Studies on Essential Oils of Plants of Angelica Genus in Korea(V) -Essential Oils of the Root of Angelica decursiva- (Angelica속 생약의 정유성분에 관한 연구(V) -바디나물의 정유성분-)

  • Chi, Hyung-Joon;Kim, Hyun-Soo
    • Korean Journal of Pharmacognosy
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    • v.24 no.3
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    • pp.192-196
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    • 1993
  • Essential oil of the root of Angelica decursiva(Miq.) Fr. et Sav. (Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain ten monoterpenes such as ${\alpha}-pinene$ (7.0%) etc. Three hydrocarbons, two aldehydes, three sesquiterpenes, two sesquiterpene alcohols, one aromatic compounds, one ketone, isobonyl acetate and two lactones were tentatively identified.

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Didymella acutilobae sp. nov. Causing Leaf Spot and Stem Rot in Angelica acutiloba

  • Gyo-Bin Lee;Ki Deok Kim;Weon-Dae Cho;Wan-Gyu Kim
    • Mycobiology
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    • v.51 no.5
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    • pp.313-319
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    • 2023
  • During disease surveys of Angelica acutiloba plants in Korea, leaf spot symptoms were observed in a field in Andong in July 2019, and stem rot symptoms in vinyl greenhouses in Yangpyeong in April 2020. Incidence of leaf spot and stem rot of the plants ranged from 10 to 20% and 5 to 30%, respectively. Morphological and cultural characteristics of fungal isolates from the leaf spot and stem rot symptoms fitted into those of the genus Phoma. Molecular phylogenetic analyses of two single-spore isolates from the symptoms using concatenated sequences of LSU, ITS, TUB2, and RPB2 genes authenticated an independent cluster from other Didymella (anamorph: Phoma) species. Moreover, the isolates showed different morphological and cultural characteristics in comparison to closely related Didymella species. These discoveries confirmed the novelty of the isolates. Pathogenicity of the novel Didymella species isolates was substantiated on leaves and stems of A. acutiloba through artificial inoculation. Thus, this study reveals that Didymella acutilobae sp. nov. causes leaf spot and stem rot in Angelica acutiloba.

Trends in the development of discriminating between Angelica L. species using advanced DNA barcoding techniques (진보된 DNA barcoding 기술을 이용한 당귀(Angelica)속 식물의 기원 판별 기술에 관한 연구 동향)

  • Lee, Shin-Woo;Shin, Yong-Wook;Kim, Yun-Hee
    • Journal of Plant Biotechnology
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    • v.48 no.3
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    • pp.131-138
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    • 2021
  • We reviewed current research trends for discriminating between species of the Angelica genus, a group of important medicinal plants registered in South Korea, China, and Japan. Since the registered species for medicinal purposes differ by country, they are often adulterated as well as mixed in commercial markets. Several DNA technologies have been applied to distinguish between species. However, one of the restrictions is insufficient single-nucleotide polymorphisms (SNPs) within the target DNA fragments; in particular, among closely-related species. Recently, amplification refractory mutation system (ARMS)-PCR and highresolution melting (HRM) curve analysis techniques have been developed to solve such a problem. We applied both technologies, and found they were able to discriminate several lines of Angelica genus, including A. gigas Nakai, A. gigas Jiri, A. sinensis, A. acutiloba Kitag, and Levisticum officinale. Furthermore, although the ITS region differs only by one SNP between A. gigas Nakai and A. gigas Jiri, both HRM and ARMS-PCR techniques were powerful enough to discriminate between them. Since both A. gigas Nakai and A. gigas Jiri are native species to South Korea and are very closely related, they are difficult to discriminate by their morphological characteristics. For practical applications of these technologies, further research is necessary with various materials, such as dried or processed materials (jam, jelly, juice, medicinal decoctions, etc.) in commercial markets.

Studies on Essential Oils of Plants of Angelica Genus in Korea (IV) -Essential Oils of Angelicae koreanae Radix- (Angelica속 생약의 정유성분에 관한 연구(IV) -강활의 정유성분-)

  • Chi, Hyung-Joon;Kim, Hyun-Soo
    • Korean Journal of Pharmacognosy
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    • v.24 no.2
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    • pp.111-115
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    • 1993
  • Essential oil of the root of Angelica koreana Max. (Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain nine monoterpenes such as ${\alpha}-pinene$(7.0%), camphene, ${\beta}-pinene$, myrcene, ${\alpha}-phellandrene$, ${\Delta}-3-carene$, p-cymene, limonene(2.8%), terpinolene and also found to contain m-cresol(11.6%), citronellol, citral b, methylcinnamate, eudesmol and osthol. 2-Hydroxy-5-methylacetophenone and twelve compounds were tentatively identified.

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Studies on Essential Oil of Plants of Angelica Genus in Korea(III) -Essential Oils of Angelicae dahuricae Radix- (Angelica속 생약의 정유성분에 관한 연구(III) -백지의 정유성분-)

  • Kim, Hyun-Soo;Chi, Hyung-Joon
    • Korean Journal of Pharmacognosy
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    • v.21 no.2
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    • pp.121-125
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    • 1990
  • Essential oil of the root of Angelica dahurica Benth et Hook(Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain eleven monoterpenes such as ${\alpha}-pinene(4.74%),\;campben, {\beta}-pinene,\;myrcene,\;{\alpha}-phellandrene,\;{\delta}-3-carene(39.4%),\;{\alpha}-terpinene,\;{\rho}-cymene,\;{\beta}-phellandrene,\;{\alpha}-terpinene,\;terpinolene\;and\;also\;found\;to\;contain\;4-vinylguaiacol,\;iso-elemicin,\;{\beta}-elemene$, caryophyllene, ligustilide, osthol and seven tentatively identified sesquiterpenes.

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Studies on Essential Oils of Plants of Angelica Genus in Korea (I). -Essential Oils of Angelicae gigantis Radix- (Angelica속 생약의 정유성분에 관한 연구 (I). -참당귀의 정유성분-)

  • Chi, Hyung-Joon;Kim, Hyun-Soo
    • Korean Journal of Pharmacognosy
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    • v.19 no.4
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    • pp.239-247
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    • 1988
  • Essential oil of the root of Angelica gigas Nakai (Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain eleven monoterpenes such as ${\alpha}-pinene,\;camphene,\;{\beta}-pinene,\;myrcene,\;{\alpha}-phellandrene,\;{\Delta}-3-carene,\;{\alpha}-terpinene,\;p-symene,\;limonene,\;{\gamma}-terpinene$ and terpinolene and also found to contain 4-vinylguauacol, myristicin, elemol, ${\beta}-eudesmol,\;{\alpha}-eudesmol,\;four\;sesquiterpenes\;involving\;{\Delta}-elemene$. Four sesquiterpenes and five sesquiterpene alcohols were tentatively identified by comparison of their mass spectra.

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Taxonomical Review for Tilingia tsusimensis (Apiaceae) (대마참나물(Tilingia tsusimensis, 산형과)의 분류학적 재검토)

  • Kim, Muyeol;So, Soonku;Seo, Eunkyoung;Park, Hyerim;Han, Kyeongsuk;Heo, Kweon
    • Korean Journal of Plant Taxonomy
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    • v.37 no.4
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    • pp.529-543
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    • 2007
  • It was revaluated about taxonomical position of the Tilingia tsusimensis (Yabe) Kitagawa (Apiaceae) collected from Mt. Gaya, Mt. Geumo, and Mt. Songni in Korea. Its diagnostic features include slightly dorsally compressed mericarps, acute-prominent ribs, ternate leaves, and dimorphic white petals. It is morphologically similar to Cymopterus and Pimpinella in having ternate leaves. It is distinguished from Cymopterus having asymmerty mericarps, 3-4 mericarp ribs, and winged dorsal ribs. Pimpinella differs in having slightly laterally compressed mericarps without ribs and conspicuous calyx teeth. Also, it looks like Angelica with obsolete calyx teeth and multilayer pericarps, but is distinguished by having its broadly winged lateral ribs and strongly dorsally compressed mericarps. Tilingia tsusimensis formed a monophyletic clade or sister group relationship with a genus Angelica based on ITS sequences. Based on the above observations, we conclude that this plant is here referred to T. tsusimensis (Yabe) Kitagawa.