• Journal of Periodontal and Implant Science
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• 제51권3호
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• pp.147-162
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• 2021

Purpose: This systematic review and meta-analysis was conducted to assess the effects of glycine powder air-polishing (GPAP) in patients during supportive periodontal therapy (SPT) compared to hand instrumentation and ultrasonic scaling. Methods: The authors searched for randomized clinical trials in 8 electronic databases for relevant studies through November 15, 2019. The eligibility criteria were as follows: population, patients with chronic periodontitis undergoing SPT; intervention and comparison, patients treated by GPAP with a standard/nozzle type jet or mechanical instrumentation; and outcomes, bleeding on probing (BOP), patient discomfort/pain (assessed by a visual analogue scale [VAS]), probing depth (PD), gingival recession (Rec), plaque index (PI), clinical attachment level (CAL), gingival epithelium score, and subgingival bacteria count. After extracting the data and assessing the risk of bias, the authors performed the meta-analysis. Results: In total, 17 studies were included in this study. The difference of means for BOP in patients who received GPAP was lower (difference of means: -8.02%; 95% confidence interval [CI], -12.10% to -3.95%; P<0.00001; I²=10%) than that in patients treated with hand instrumentation. The results of patient discomfort/pain measured by a VAS (difference of means: -1.48, 95% CI, -1.90 to -1.06; P<0.001; I²=83%) indicated that treatment with GPAP might be less painful than ultrasonic scaling. The results of PD, Rec, PI, and CAL showed that GPAP had no advantage over hand instrumentation or ultrasonic scaling. Conclusions: The findings of this study suggest that GPAP may alleviate gingival inflammation more effectively and be less painful than traditional methods, which makes it a promising alternative for dental clinical use. With regards to PD, Rec, PI, and CAL, there was insufficient evidence to support a difference among GPAP, hand instrumentation, and ultrasonic scaling. Higher-quality studies are still needed to assess the effects of GPAP.

• Nuclear Engineering and Technology
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• 제52권4호
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• pp.721-733
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• 2020

In nuclear engineering, the occurrence of critical heat flux (CHF) is complicated for rod bundle, and it is much more difficult to predict the CHF when it is in natural circulation under motion condition. In this paper, the dryout-type CHF is investigated for the rod bundle in a natural circulation loop under rolling motion condition based on the coupled analysis of subchannel method, a one-dimensional system analysis method and a CHF mechanism model, namely the three-fluid model for annular flow. In order to consider the rolling effect of the natural circulation loop, the subchannel model is connected to the one-dimensional system code at the inlet and outlet of the rod bundle. The subchannel analysis provides the local thermal hydraulic parameters as input for the CHF mechanism model to calculate the occurrence of CHF. The rolling motion is modeled by additional motion forces in the momentum equation. First, the calculation methods of the natural circulation and CHF are validated by a published natural circulation experiment data and a CHF empirical correlation, respectively. Then, the CHF of the rod bundle in a natural circulation loop under both the stationary and rolling motion condition is predicted and analyzed. According to the calculation results, CHF under stationary condition is smaller than that under rolling motion condition. Besides, the CHF decreases with the increase of the rolling period and angular acceleration amplitude within the range of inlet subcooling and mass flux adopted in the current research. This paper can provide useful information for the prediction of CHF in natural circulation under motion condition, which is important for the nuclear reactor design improvement and safety analysis.

• 한국터널지하공간학회 논문집
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• 제12권3호
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• pp.275-283
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• 2010

최근 터널의 정보화 설계시공이 중요시 되어지고 있다. 암반에는 절리, 단층, 균열, 층리, 단열 등의 불연속면이 많이 포함되어 있다. 따라서, 암반 불연속면이 터널의 거동을 좌우하고 있다. 본 연구에서는 터널의 정보화 설계시공을 위한 키블럭 해석기법을 제안하고, 초대단면 터널현장에 적용했다. 제안한 해석기법은 불연속면의 연속성을 고려하여, 블록의 형상에 관계없이 모든 형상의 블록이 인식 가능하여 복잡한 굴착면에 적용가능하다. 터널현장에서의 해석결과를 비교 검토하여, 본 연구에서 개발한 터널의 정보화 설계시공을 위한 키블럭 해석기법의 타당성과 적용성에 대한 검증을 하였다.

• Plant Biotechnology Reports
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• 제5권1호
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• pp.71-77
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• 2011

Drought and salinity are the most important abiotic stresses that affect the normal growth and development of plants. Glycine betaine is one of the most important osmolytes present in higher plants that enable them to cope with environmental stresses through osmotic adjustment. In this study, a betaine aldehyde dehydrogenase (BADH) gene from spinach under the control of the stress-induced promoter rd29A from Arabidopsis thaliana was introduced into potato cultivar Gannongshu 2 by the Agrobacterium tumefaciens system. Putative transgenic plants were confirmed by Southern blot analysis. Northern hybridization analysis demonstrated that expression of BADH gene was induced by drought and NaCl stress in the transgenic potato plants. The BADH activity in the transgenic potato plants was between 10.8 and 11.7 U. There was a negative relationship (y = -2.2083x + 43.329, r = 0.9495) between BADH activity and the relative electrical conductivity of the transgenic potato plant leaves. Plant height increased by 0.4-0.9 cm and fresh weight per plant increased by 17-29% for the transgenic potato plants under NaCl and polyethylene glycol stresses compared with the control potato plants. These results indicated that the ability of transgenic plants to tolerate drought and salt was increased when their BADH activity was increased.

• Nuclear Engineering and Technology
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• 제53권3호
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• pp.763-775
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• 2021

The thermal hydraulic performances of Steam Generator (SG) under both steady and transient operation conditions are of great importance for the safety and economy in nuclear power plants. In this paper, based on our self-developed SG thermal hydraulic analysis code STAF (Steam-generator Thermalhydraulic Analysis code based on Fluent), an improved new version STAF-CT (fully Coupling and Transient) is developed and introduced. Compared with original STAF, the new version code STAF-CT has two main functional improvements including "Transient" and "Fully Three Dimensional Coupling" features. In STAF-CT, a three dimensional energy transferring module is established which can achieve energy exchange computing function at the corresponding position between two sides of SG. The STAF-CT is validated against the international benchmark experiment data and the results show great agreement. Then the U-shaped SG in AP1000 nuclear power plant is modeled and simulated using STAF-CT. The results show that three dimensional flow fields in the primary side make significant effect on the energy source distribution between two sides. The development of code STAF-CT in this paper can provide an effective method for further SG high fidelity research in the nuclear reactor system.

• 한국정보처리학회논문지
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• 제7권6호
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• pp.1874-1885
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• 2000

When a receiver of ciphertext message can not decrypt a message because he has lost his private-key, the private-key of receiver and session-key of the message should be recovered. In this paper, we developed an Encapsulation based Key Recovery System (EKRS). EKRS is a new key encapsulation based key recovery system which is characterized by secretly choice of KRA, randomized target keys. n-way recovery type, and useful for commercial key recovery. EKRS is formally specified by a pictorial model, an Extended Cryptographic Timed Petri Net (ECTPN). Secure information flow and reachability of a session-key are verified by using reachability graph of ECTPN. EKRS, executing over a Public Key Infrastructure, can be used as a security solution in Web based applications such as CALS, EC an EDI.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5749-5754
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• 2015

Cervical carcinoma is the main cause of cancer-related mortality in women and is correlated with more than 15 risk cofactors, including infection of cervical cells with high-risk types of HPV (hrHPV). Indeed, both aberrant methylation of the RASSF1A promoter and hrHPV infection are often observed in cervical carcinomas. The purpose of our meta-analysis was to evaluate the role of RASSF1A promoter methylation and hrHPV infection in cervical cancer. Our meta-analysis involved 895 cervical cancer patients and 454 control patients from 15 studies. Our results suggested that RASSF1A promoter hypermethylation increased the risk of cervical cancer (OR=9.77, 95%CI=[3.06, 31.26], P=0.0001, $I^2=78%$). By grouping cases according to cancer subtypes, we found that HPV infection was higher in cervical squamous cell carcinomas (SCCs) than in cervical adenocarcinomas/adenosquamous cancers (ACs/ASCs) (OR=4.00, 95%CI=[1.41, 11.30], P=0.009, $I^2=55%$). Interestingly, HPV infection tended to occur in cervical cancers with relatively low levels of RASSF1A promoter methylation (OR=0.59, 95%CI=[0.36, 0.99], P=0.05, I2=0%). Our study provides evidence of a possible interaction between HPV infection and RASSF1A promoter methylation in the development of cervical cancers.

• 한국조리학회지
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• 제23권5호
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• pp.58-66
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• 2017

The purpose of this study was to assess priority of educational needs for the development of curriculum based on key competencies of NCS for departments related to culinary arts in a 2-year college. In order to achieve this objective, the survey has been distributed to cooks working in hotel restaurants or restaurant companies by social network service and a total of 360 responses were analyzed excluding 18 responses. The collected surveys were analysed by using paired t-test, Borich's needs analysis and the locus for focus analysis. The results of this study were as follows. First, the difference between the level of importance and present level about key competencies recognized by cooks working in restaurant company was statistically significant in 9 fields of key competencies excluding mathematical competence. The difference recognized by cooks working in hotel was statistically significant in all 10 fields of key competencies. Second, the results of Borich's needs assessment showed that the education needs of problem solving competence were the highest, followed by interpersonal, resource management, communication, information competence. Finally, considering both Borich's needs assessment and the locus for focus analysis, cooks working in hotel restaurants recognized that educational needs of communication, interpersonal, problem-solving, information competence were the top priority, and cooks working in restaurant companies recognized that educational needs of communication, interpersonal, skill, resource management competence were the top priority. Therefore, it is necessary to develop curriculum for culinary arts specialists based on key competence of top priority.

• Parasites, Hosts and Diseases
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• 제54권1호
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• pp.39-46
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• 2016

Theileria annulata is a tick-borne intracellular protozoan parasite that causes tropical theileriosis, a fatal bovine lymphoproliferative disease. The parasite predominantly invades bovine B lymphocytes and macrophages and induces host cell transformation by a mechanism that is not fully comprehended. Analysis of signaling pathways by quantitative real-time PCR (qPCR) could be a highly efficient means to understand this transformation mechanism. However, accurate analysis of qPCR data relies on selection of appropriate reference genes for normalization, yet few papers on T. annulata contain evidence of reference gene validation. We therefore used the geNorm and NormFinder programs to evaluate the stability of 5 candidate reference genes; 18S rRNA, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), ACTB (${\beta}-actin$), PRKG1 (protein kinase cGMP-dependent, type I) and TATA box binding protein (TBP). The results showed that 18S rRNA was the reference gene most stably expressed in bovine PBMCs transformed and non-transformed with T. annulata, followed by GAPDH and TBP. While 18S rRNA and GAPDH were the best combination, these 2 genes were chosen as references to study signaling pathways involved in the transformation mechanism of T. annulata.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.2
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• pp.91-96
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• 2006

Presently, cycle-slip detection is done between adjacent two points in many cycle-slip methods. Inherently, it is simple wavelet analysis. A new idea is put forward that the number of difference point can adjust by a parameter factor; we study this method to smooth raw data and detect cycle-slip with wavelet analysis. Taking CHAMP satellite data for example, we get some significant conclusions. It is showed that it is valid to detect cycle-slip in GPS phase measurement based on this wavelet function, and it is helpful to improve the precision of GPS data pre-processing and positioning.