• 한국언어정보학회지:언어와정보
• /
• 제5권2호
• /
• pp.57-74
• /
• 2001

In this paper, I propose syntactic, semantic and pragmatic restrictions on the distribution of the contrastive topic marker‘-(n)un’in Korean. A contrastive topic is associated with another focus. The association with focus is subject to syntactic islands. On the other hand, there is no syntactic restriction between a phrase attached with‘-(n)un’and a focused expression within the ‘-(n)un’phrase itself. In this area there is a semantic requirement that the alternatives generated by a focused expression be maintained up to the phrase attached with‘-(n)un’. Finally, when‘-(n)un’is used in an embedded clause, the whole sentence becomes natural when the contrastive topic introduced by‘-(n)un’and its alternative contrastive topic, which is presupposed by the contrastive topic marker, jointly constitute a more complex topic which is related to the whole context. And exclusiveness facilitates the formation of the whole complex context.

• Journal of Life Science
• /
• 제11권2호
• /
• pp.120-125
• /
• 2001

The pyrR gene of the pyrimidine biosynthesis (pyr) operon of the thermophile Bacillus caldolyticus, encoding a uracil phosphoribosyltransferase (UPRTase), turned to rely as a pyr operon regulator. It has been proposed that PyrR mediates transcriptional termination-antitermination at three intercistronic regions of the par operon (S.-Y Ghim and J. Neuhard, J. Bacteriol.,176, 3698-3707, 1994). In this research, a plasmid carrying the pyrR region of B. caldolyticus could restore a pyrimidine regulation in a pyrR mutant of B. subtilis. Expression of pyrR was found to increase 6-7 fold during pyrimidine starvation. Additionally, a highly conserved nucleotide sequence which may constitute the binding site for a PyrR protein (PyrR-binding loop) in transcript was staggested. Alternative antiterminator and terminator structures involving three conserved motifs in front of the pyrR, pyrP and pyrB genes, respectively, are proposed to account for the observed regulation pattern.

• Molecules and Cells
• /
• 제40권1호
• /
• pp.1-9
• /
• 2017

Serine and arginine-rich (SR) proteins are RNA-binding proteins (RBPs) known as constitutive and alternative splicing regulators. As splicing is linked to transcriptional and post-transcriptional steps, SR proteins are implicated in the regulation of multiple aspects of the gene expression program. Recent global analyses of SR-RNA interaction maps have advanced our understanding of SR-regulated gene expression. Diverse SR proteins play partially overlapping but distinct roles in transcription-coupled splicing and mRNA processing in the nucleus. In addition, shuttling SR proteins act as adaptors for mRNA export and as regulators for translation in the cytoplasm. This mini-review will summarize the roles of SR proteins as RNA binders, regulators, and connectors from transcription in the nucleus to translation in the cytoplasm.

• Computers and Concrete
• /
• 제24권4호
• /
• pp.295-302
• /
• 2019

Evolutionary algorithms based on conventional statistical methods such as regression and classification have been widely used in data mining applications. This work involves application of gene expression programming (GEP) for predicting compressive strength of fly ash geopolymer concrete, which is gaining increasing interest as an environmentally friendly alternative of Portland cement concrete. Based on 56 test results from the existing literature, a model was obtained relating the compressive strength of fly ash geopolymer concrete with the significantly influencing mix design parameters. The predictions of the model in training and validation were evaluated. The coefficient of determination ($R^2$), mean (${\mu}$) and standard deviation (${\sigma}$) were 0.89, 1.0 and 0.12 respectively, for the training set, and 0.89, 0.99 and 0.13 respectively, for the validation set. The error of prediction by the model was also evaluated and found to be very low. This indicates that the predictions of GEP model are in close agreement with the experimental results suggesting this as a promising method for compressive strength prediction of fly ash geopolymer concrete.

• Toxicological Research
• /
• 제35권1호
• /
• pp.25-35
• /
• 2019

The extracts of Plathymenia reticulata and Connarus favosus are widely used in the folk medicine. The potential protective effects of these extracts have been evaluated against cadmium in the yeast Saccharomyces cerevisiae, and against mercurial contamination in zebrafish Danio rerio. In yeast, both extracts efficiently protected the ${\Delta}ycf1$ mutant strain exposed to cadmium chloride restoring the growth, the expression of stress-response genes and decreasing the level of oxidative stress. In zebrafish, the supplementation of methylmercury-contaminated diet with both plant extracts similarly protected fish through the suppression of the methylmercury-induced lipid peroxidation, decrease of acetylcholinesterase activity, and restoring the expression levels of stress-response genes. This study particularly demonstrates the protective potential of both aqueous extracts against methylmercury, and could represent an interesting alternative for the Amazonian fish-eating communities to cope with the impact of chronic exposure to contaminated diets.

• 한국미생물·생명공학회지
• /
• 제50권2호
• /
• pp.240-244
• /
• 2022

Precisely reliable and quantitative reporters can provide phenotypes that are consistent with research goals in protein expression. Here, we developed an improved reporter mATglu III 5 by directed evolution using a versatile β-glucosidase ATglu derived from Agrobacterium tumefaciens. When expressed in hosts, a vector containing this mutant distinctly showed a colored or fluorescent phenotype, according to the supplemented substrate, without any inducer. Analysis of mATglu III 5 showed it to be fully functional in fusion state with oligomeric proteins, especially under non-induction conditions, thereby offering an alternative to conventional reporters.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2000년도 봄 학술발표회 논문집
• /
• pp.515-520
• /
• 2000

The state-of-the-practice design expressions currently used for the calculation of shear strength of concrete columns due to circular transverse hoop steel were reviewed. From this, it was found that the single valued constant effective section area of shear steel to be conservative in some degree that concrete sections built in non-seismic regions. A general expression as n alternative was suggested considering the wide range of section configurations. The theoretical prediction was validated through the experimental observations.

• 한국실내디자인학회:학술대회논문집
• /
• 한국실내디자인학회 2002년도 춘계학술발표대회 논문집
• /
• pp.125-129
• /
• 2002

Economic growth and complex urbanization due to modern rapid industrialization prompt us necessarily to require rests and civic entertainments. Various leisure activities appear to be the type of theme park which has compound natures, and now these are being developed to leisure cultures with new conception. Here, this study presents a desirable direction of new entertainment through virtual reality in the theme park type of the 21st century's alternative entertaining space that citizens are easily accessible, maximizes experiences and meets the entertainment instinct.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제12권4호
• /
• pp.1674-1692
• /
• 2018

An RFID network is a network in which a reader inquire about the identities of tags and tags respond with their identities to a reader. The diversity of RFID networks has brought about many applications including an inexpensive system where a single reader supports a small number of tags. Such a system needs a tag cognizance scheme that is able to arbitrate among contending tags as well as is simple enough. In this paper, confining our attention to a clan of simple schemes, we propose a randomized scheme with aiming at enhancing the tag cognizance rate than a conventional scheme. Then, we derive an exact expression for the cognizance rate attained by the randomized scheme. Unfortunately, the exact expression is not so tractable as to optimize the randomized scheme. As an alternative way, we develop an upper bound on the tag cognizance rate. In a closed form, we then obtain a nearly optimal value for a key design parameter, which maximizes the upper bound. Numerical examples confirm that the randomized scheme is able to dominate the conventional scheme in cognizance rate by employing a nearly optimal value. Furthermore, they reveal that the randomized scheme is robust to the fallacy that the reader believes or guesses a wrong number of neighboring tags.

• 복식
• /
• 제54권3호
• /
• pp.13-25
• /
• 2004

The purpose of this study was to show the analysis system and the expression which is applied to fashion illustration by three major components in visual sign, metaphor and metonymy. The results of this study were as follows : Firstly, metaphor in qualisign of syntactics was revealed as a color such as realistic description, a pattern such as clothing of figure. etc. Metonymy was revealed as a social and cultural background color, a concept pattern. etc. In sinsign of syntactics. metaphor was revealed as a human body, non-human body and metamorphosis human body and metonymy as a human body and non-human body. In legisign of syntactics, the metaphor by perspective was used for a fantasy of space. and the metonymy was revealed as a color perspective representation, etc. The degree of change of texture was revealed as a metaphor and metonymy of gradation. And conventional custom sign was almost revealed in metaphor. Secondly, semantics showed about fashion image as juxtaposition of two similar objects in metaphor and as real description and simplification in metonymy Alternative fashion image in semantics was presented as a object related to fashion image. Conventional symbolic sign was presented as a role to clarify a fashion message in metaphor. Thirdly, the metaphorical and metonymical expression in pragmatics were usually presented as drawing and painting.