• 동의생리병리학회지
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• 제17권3호
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• pp.777-779
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• 2003

Among extracts prepared from Alstonia scholaris, Phyllostachys pubescens and Bambusa veitchii, methanol fraction of Alstonia scholaris was found to have antiplasmodial effect by inhibiting growth of the chloroquine-resistant Plasmodium falciparum strain FCR-3 with less than 14 μg/ml of EC50 values. Methanol fraction 2 of Alstonia scholaris revealed the strongest anti plasmodial effect with 40 μg/ml of EC50 value. Especially, this fraction showed higher than 3-folds selective toxicity on a Plasmodium as the EC value was 116 μg/ml on the host FM3A cell. This is the first report on which an extract compound from Alstonia scholaris showed antimalarial effect.

• Advances in Traditional Medicine
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• 제7권3호
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• pp.254-260
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• 2007

Alstonia scholaris (Family: Apocynaceae) has been indicated for the treatment of various diseases, one among which is wound healing. The purpose of this study is to investigate the wound healing effect and antioxidant role of Alstonia scholaris leaves in animal models. The ethanol and aqueous extracts of Alstonia scholaris (EEAS, AEAS respectively) were tested against excision, incision and dead space wound models to evaluate the wound healing activity. In excision wound model, treatment was continued till the complete healing of wound, in incision and dead space wound models, the treatment was continued for 10 days. For topical application, 5% w/w ointment of EEAS and AEAS were prepared in 2% sodium alginate. For oral administration, EEAS was suspended in distilled water using Tween 80 and AEAS was dissolved in distilled water. The wound healing was assessed by the rate of wound contraction, period of epithelialisation, skin breaking strength, granulation strength, dry granulation tissue weight, hydroxyproline, collagen and histopathology of granulation tissue. Malondialdehyde level was also estimated to evaluate the extent of lipid peroxidation. AEAS and EEAS significantly promoted wound healing activity in all the wound models studied. Increase in the rate of wound contraction, skin breaking strength, granulation strength, dry granulation tissue weight, hydroxyproline and collagen, decrease in the period for epithelialisation and increased collagenation in histopathological section were observed with EEAS and AEAS treated groups. EEAS and AEAS also significantly decreased the levels of lipid peroxidation. The present study is suggestive that EEAS and AEAS promote wound healing activity.

• Natural Product Sciences
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• 제12권4호
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• pp.241-246
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• 2006

Alstonia scholaris is known as 'Saptaparna' in Ayurvedic System of Medicines and the bark is used for the treatment of various diseases. It has various ethnomedicinal values as different traditional communities find diverse medicinal properties. The present communication deals with the seasonal variation studies of the stem bark of this plant. The bark was collected in the month of January, July and November. There is no macro-microscopical changes in all the three seasons but the ash values showed significant differences. Crude fibre content showed sharp decline from January to July to November. Total tannin percentage was found maximum in January and minimum in June. TLC finger print profile showed more concentration of constituents in January as compared to June and November. Hence, the bark may show more efficacy when collected in January.

• Advances in nano research
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• 제4권4호
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• pp.281-294
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• 2016

The advantages of nano-scale materials (size 1-99 nm in at least in one dimension) could be realized with their potential applications in diversified avenues. Herein, we report for the first time on the successful synthesis of homogeneous epoxy coatings containing phytogenic silver nanoparticles (Ag) on PVC and glass substrates by room-temperature curing of fully mixed epoxy slurry diluted by acetone. Alstonia scholaris bark extract was used to reduce and stabilize the silver ions. The surface morphology and mechanical properties of these coatings were characterized using the techniques like, UV-Vis (UV-Visible) spectrophotometry, X-ray diffraction (XRD), Fourier transform infrared spectrophotometry (FT-IR), Epifluorescence microscopy and scanning electron microscopy (SEM). The effect of incorporating Ag nanoparticles on the biofilm (scale) resistant epoxy-coated PVC was investigated by total viable counts ($CFU/cm^2$) from epoxy coating from (Initial) $1^{st}$ day to $25^{th}$ days. The phytogenic Ag nanoparticles were found to be significantly improving the microstructure of the coating matrix and thus enhanced the anti-biofilm performance of the epoxy coating. In addition, the antimicrobial mechanism of Ag nanoparticles played an important role in improving the anti-biofilm performance of these epoxy coatings.

• Asian Journal of Atmospheric Environment
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• 제10권3호
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• pp.162-167
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• 2016

This study was conducted in an industrial city (Bilaspur) representative of subtropical area in central India. In order to assess the metal deposition on plant, concentrations of six target metals (i.e., Fe, Mn, Pb, Cu, Cd, and Cr) in both plant leaf and dust (deposited on its surface) samples were measured from six different sites. Metal concentrations in dust samples were found on the order of Fe>Mn> Cr>Pb>Cu>Cd. In contrast, the concentration of metals in plant leaves were seen on the order of Fe>Mn>Cr>Cd>Cu>Pb. As such, Cd showed significantly high concentration in leaves relative to their corresponding dust samples. A high accumulation potential for Fe and Cd was seen from Butea monosperma, while Mn and Pb were accumulated noticeably in Pongamia pinnata and Butea monosperma. Likewise, Cr and Cu were enriched in Calotropis procera, Alstonia scholaris, and Butea monosperma. The overall results of our study suggest that the foliar uptake pattern should vary considerably by an interactive role between plant and metal types.

• The Plant Pathology Journal
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• 제38권2호
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• pp.131-145
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• 2022

Ceratocystis wilt disease has caused significant mortality in duku (Lansium domesticum) since 2014 and has now spread to all districts in South Sumatra, Indonesia. Recently, 16 isolates from duku representing populations from various districts in South Sumatra were isolated. Analysis for the morphological characteristic of the isolate showed that the population has a uniform morphology. Genetic analysis based on internal transcribed spacer (ITS) and β-tubulin sequences verified that the population has being dominated by the ITS5 haplotype of Ceratocystis fimbriata and a new ITS group, the ITS7b haplotype that was localized in Musi Banyuasin. Both haplotypes were highly pathogenic to duku. Inoculation tests on various forest and agroforestry plant hosts showed that both haplotypes were highly pathogenic to Acacia mangium, moderately pathogenic to Acacia carsicarpa, Eucalyptus urophylla, and Melaleuca cajuputi, but weakly pathogenic to Dyera costulata, Hevea brasiliensis, and Alstonia scholaris. Therefore, this pathogen becomes a serious threat to Indonesia's biodiversity due to its ability to infect forest and agroforestry plants, especially the indigenous ones.

• Journal of Forest and Environmental Science
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• 제25권3호
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• pp.167-175
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• 2009

An exploratory study was conducted in Juri Forest Range-2, a proposed biodiversity conservation area of Bangladesh to explore the present growing stock of tree, regeneration condition and status of non-timber forest products (NTFPs). This conservation area contains both natural and artificial plantation was selected by using multistage random sampling method. For determination of plot size and sampling methods, the quadrate size ($10m{\times}10m$) for tree stock measurement, ($2m{\times}2m$) for regeneration survey, ($20m{\times}20m$) for NTFPs survey was determined. Regarding tree stock survey, 14 species under eight families were found where Tectona grandis shows average number of stem/ha was 624 and basal area/ha was (10.36 $m^2/ha$) followed by Acacia auriculiformis (0.2 $m^2/ha$ and 637 stem/ha), Gmelina arborea (0.2 $m^2/ha$ and 600 stem/ha). In regeneration survey, 14 species were found belonging to 9 families where Alstonia scholaris shows highest (3,750) seedling per hectare. Regarding NTFPs, bamboo and cane are the most common resources. In last ten years, the total timber output was 1,28,596.14 cubic feet and total amount of revenue was 4,64,434 US$. The vacant area is 1,335.5 acre which contains 14% of total area. If this vacant area is planted with suitable species and take proper steps for appropriate management of this species it will be a good biologically diversified area.