• 약학회지
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• 제42권3호
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• pp.296-301
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• 1998

To investigate the effects of ginsenosides from Panax ginseng on mitogenic responses in macrophages and splenocytes from murine, we examined the effects of representative protopanaxadiol and protopanaxatriol ginsenosides ($Rb_1,\;Rb_2,\;Re\;and\;Rg_1$) on tumor necrosis factor-${\alpha}$ (TNF-(${\alpha}$) production in murine macrophage cell line (RAW264.7 cells) stimulated by lipopolysaccharide (LPS) and T cell proliferation in splenocytes stimulated by concanavalin A (Con A). Among the ginsenosides tested, protopanaxadiol ginsenosides ($Rb_1\;and\;Rb_2$) significantly inhibited TNF-${\alpha}$ production in a dose-dependent manner. However, protoppanaxatriol ginsenosides (Re and $Rg_1$) showed little inhibitory activity. The molar concentrations of $Rb_1\;and\;Rb_2$ producing 50% inhibition ($IC_{50}$) of TNF-${\alpha}$ production were $55.8{\mu}g/ml\;(48.0{\mu}M)\;and\;31.8{\mu}g/ml (27.9{\mu}M)$, respectively. As a positive control, prednisolone also exhibited inhibitory activity with an $IC_{50}$ value of $21.7{\mu}M$. In T cell proliferation, $Rg_1$, was not effective but $Rb_1$ and Re or $Rb_2$ significantly increased or inhibited at high concentration, 75 and $100{\mu}g/ml$. In contrast, prednisolone showed potent inhibitory activity with an $IC_{50}$ value of 6.1nM. These results suggest that ginsenosides may take part in the mitogen-induced signaling pathway for TNF-${\alpha}$ production and T cell proliferation from macrophages and splenocytes.

• Elastomers and Composites
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• 제47권1호
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• pp.23-29
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• 2012

실리카가 충전된 천연고무 복합소재 내에서 실란 함량의 증가가 실리카간의 구조 발달 상수 (${\alpha}_F$)에 미치는 영향을 비교하였다. 동일한 실리카양 (10, 20, 30, 40 phr)에서 실란의 함량 (2, 4, 6, 8, 10, 12%)이 증가할수록 ${\alpha}_F$값이 증가하는 경향이 나타났다. 이는 실란내 존재하는 황이 가교에 참여하였기 때문인 것으로 판단된다. 또한 실란 함량이 같은 조건에서 실리카양이 증가할수록 ${\alpha}_F$값이 증가하였는데 이는 실리카 간 상호관계가 증가하였기 때문인 것으로 판단된다.

• 대한치과기공학회지
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• 제28권1호
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• pp.27-41
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• 2006

The physical property and phase transformation in a commercial dental casting high gold alloy was investigated as a function of ageing temperature and time using microvickers hardness tester, X-ray diffraction, optical and electron microscopy and EPMA analyser. 1. With increasing ageing time, the hardness of solution-treated gold alloys increased slowly at the initial stage of ageing treatment at an ageing temperature of $300{\sim}400^{\circ}C$, and it reached a maximum value of hardness at the medium stage. Finally, it decreased gradually during further ageing. The maximum value of hardness at was similar with that of the conventional materials and suitable for using as the crown & bridge. 2. During isothermal ageing at a temperature range of $300{\sim}400^{\circ}C$, three phases consisting of the Au-rich ${\alpha}_1$phase with a face-centered cubic structure, the Pt3Zn ${\alpha}_2$phase with an ordered AuCu3(L12) type(f.c.c.) and the Pt-rich ${\alpha}_3$phase with face-centered cubic structure in solution-treated gold alloys were transformed into different three phases consisting of the ${\alpha}_1$phase, the ${\alpha}_3$phase and the PtZn $\beta$phase with an ordered AuCu I(L10) type. 3. The hardening of gold alloys was attributed to the lattice strains of the matrix resulting from the transformation of the ${\alpha}_2$phase to the $\beta$phase. 4. The softening of gold alloys during over-ageing was attributed to the coarsening of the nodules consisting of the $\beta$phase and ${\alpha}_1$matrix.

• 생약학회지
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• 제40권2호
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• pp.150-154
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• 2009

We examined ethanol extracts prepared from the Korean marine algae belonging to the Sargassaceae family for their inhibitory effects on ${\alpha}$-glucosidase activity and free radicals in vitro. Among five marine algae, the extracts of Sargassum yezoense were found to possess strongly ${\alpha}$-glucosidase inhibition and free radicals scavenging activities. Two compounds were isolated via bioactivity guided isolation and tested for their effects on ${\alpha}$-glucosidase, DPPH, $ABTS^{+}$ and $Photochem^{(R)}$ analysis. Their chemical structures were elucidated by spectral analysis and direct comparison with authentic compounds; their structures were identified as sargaquinoic acid (1) and sargahydroquinoic acid (2). The inhibitory effects of compound 1 and 2 ($IC_{50}$ value:14.2 and 12.8 ${\mu}M$, respectively) on ${\alpha}$-glucosidase were more potent that of deoxynojirimycin as a positive control ($IC_{50}$ value:18.0 ${\mu}M$). All compounds displayed antioxidative activity which was measured by DPPH, $ABTS^{+}$ and $Photochem^{(R)}$ apparatus.

• 한국수소및신에너지학회논문집
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• 제18권2호
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• pp.116-123
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• 2007

[ $La_{0.5}Ce_{0.5}Co_{1-x}Cu_xO_{3-{\alpha}}$ ](X=0, 0.1, 0.3, 0.5) perovskites were prepared by coprecipitation method at pH 7 or pH 11 and its catalytic activity of selective CO oxidation was investigated. The characteristics of these catalysts were analyzed by $N_2$ adsorption, X-ray diffraction(XRD), SEM, $O_2$-temperature programmed desorption(TPD). The pH value at a preparation step made effect on particle morphology. The smaller particle was obtained with a condition of pH 7. The better catalytic activity was observed using catalysts prepared at pH 7 than pH 11. The maximum CO conversion of 98% was observed over $La_{0.5}Ce_{0.5}Co_{0.7}Cu_{0.3}O_{3-{\alpha}}$ at $320^{\circ}C$. Below $200^{\circ}C$, the most active catalyst was $La_{0.5}Ce_{0.5}Co_{0.9}Cu_{0.1}O_{3-{\alpha}}$, of which conversion was 92% at $200^{\circ}C$. By the substitution of Cu, the evolution of ${\alpha}$-oxygen was remarkably enhanced regardless of pH value at preparation step according to $O_2$-TPD. Among the different ${\alpha}$-oxygen species, the oxygen species evolved between $400^{\circ}C$ and $500^{\circ}C$, gave the better catalytic performance for selective CO oxidation including $La_{0.5}Ce_{0.5}CoO_3$ in which Cu was absent.

• 한국식품영양과학회지
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• 제24권3호
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• pp.371-377
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• 1995

The effect of ${\alpha}$-tocopherol and ${\beta}$-carotene supplementation on reducing the oxidative damag in the liver of rats were studied. Forth-five male Sprague Dawley aged 4 weeks were randomly assigned to 9 groups of five for the 12 weeks of the study. Nine groups, sardine oil, sardine oil＋Vt E, sardine oil＋${\beta}$-carotene, soybean oil, soybean oil＋Vt E, soybean oil＋${\beta}$-carotene, lard, lard＋Vt E, lard＋${\beta}$-carotene group, were prepared. Sardine oil, soybean oil, or lard was used for dietary fat and 200% of ${\alpha}$ -tocopherol or 150% of ${\beta}$-carotene was supplemented to each diet. Each diet supplied 65% of total energy as carbohydrate, 15% as protein, and 20% as lipid. The MDA value and protein carbonyl contents of sardine oil group were significantly different(p<0.05) to those of other fat groups indicating that the most severe lipid oxidation occurred in the group fed diet containing highly polyunsaturated fatty acid. When ${\alpha}$-tocopherol or ${\beta}$ -carotene was supplemented to the sardine oil diet, MDA value(-35%, -15%, respectively) and protein carbonyl content(-44%, -32%, respectively) decreased significantly(p<0.05). Cu, Zn-superoxide dismutase(SOD) and catalase activities of three different sardine oil groups with or without antioxidants were lower than those of soybean oil or lard group. The reducing effect of ${\alpha}$-tocopherol on oxidative damage in sardine oil group supplemented with ${\alpha}$-tocopherol was noticeable(p<0.05). However the adverse effect of ${\beta}$-carotene was observed. SOD and catalase activities of ${\beta}$-carotene supplemented groups were that the lowest among the same fat groups, but the differences were not statistically significant. The possible cause of decreased enzyme activity seemed to be related to the vitamin A(Vt A) toxicity in the liver where retinol converted from dietary ${\beta}$-carotene in the intestinal mucosa was stored.

• 한국의류산업학회지
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• 제11권4호
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• pp.556-565
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• 2009

This study investigates the effect of Alpha-numeric brand name on the product suitability, brand personality, and attitude. To do that we have chosen the functional sportswear, knowing the fact that the Alpha-numeric brand names are not hard to find in this industry. The changes have been made to Alpha-numeric names, such as the usage/non-usage of number, the size of number being used, the writing method, and the different typeface to suit for the study purpose. The results indicate that the Alpha-numeric brand names do have the effect on increasing the fitness for the product's brand. The bigger number and the cursive script will improve the product's suitability. The customers form positive attitude and favorability on the Alpha-numeric brand name compared to the regular brand name in this industry. The contribution of the study is to dig out the distinction of the communicational effects on the customers when the Alpha-numeric brand names take on the different forms. Therefore the current study enlights the practical value of Alpha-numeric brand name as part of the branding strategy.

• 터널과지하공간
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• 제7권4호
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• pp.293-298
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• 1997

Permeability was not represented as a simple function of the difference between confining pressure($P_c$) and pore pressure($P_p$). The effective pressure($P_e$) for measurements of the permeability is shown to be $P_c-{\alpha}P_p$, where $\alpha$ is a coefficient of effective pressure. Local values of $\alpha$ were determined at intervals along the pressure path which range 25MPa to 55MPa. The values of $\alpha$ ranged 0.65 to 1.09 for Pocheon granite and 1.20 to 1.43 for Wonju granite. Also, the value of $\alpha$ calculated by the cross-plotting method was 0.90 for Pocheon granite, 1.59 for Wonju granite and 4.35 for jointed Pocheon granite. $\alpha$ was found to be stress-history dependent.

• 충청수학회지
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• 제21권2호
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• pp.279-285
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• 2008

This paper presents some characterizations of the Weibull distribution by the independence of record values. We prove that $X{\sim}Weibull(1,{\alpha})$, ${\alpha}>0$ if and only if $\frac{X_{U(n+1)}}{X_{U(n+1)}-X_{U(n)}}$ and $X_{U(n+1)}$ for $n{\geq}1$ are independent. We show that $X{\sim}Weibull(1,{\alpha})$, ${\alpha}>0$ if and only if $\frac{X_{U(n+1)}}{X_{U(n+1)}-X_{U(n)}}$ and $X_{U(n+1)}$ for $n{\geq}1$ are independent. And we establish that $X{\sim}Weibull(1,{\alpha})$, ${\alpha}>0$ if and only if $\frac{X_{U(n+1)}+X_{U(n)}}{X_{U(n+1)}-X_{U(n)}}$ and $X_{U(n+1)}$ for $n{\geq}1$ are independent.

• 한국식품과학회지
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• 제22권6호
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• pp.603-610
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• 1990

쌀가루로부터 추출한 냉수가용 ${\alpha}-D-glucan$의 blue value는 $0.026{\sim}0.030$, 극대흡수파장은 $518{\sim}522nm$, ${\beta}-amyolysis\;limit$는 $52.7{\sim}59.6%$ 정도의 범위를 나타내어 이들 물질은 아밀로펙틴에 유사한 성질을 지니고 있었으며, 또한 이들 ${\alpha}-D-glucan$에 가지절단효소인 pullulanase를 처리한 후 분해물의 쇄장분포를 조사한 결과 이들 ${\alpha}-D-glucan$은 쌀아밀로펙틴의 unit chain 분포와 유사하였고, 또한 이들 분해물에 대해 중합도 30 이하의 쇄장분포는 쌀가루 냉수추출 ${\alpha}-D-glucan$ 중 blade mill의 것만이 아밀로펙틴과 유사한 쇄장분포를 나타내었고 중합도 10 이하의 구성비에 있어서는 냉수추출 ${\alpha}-D-glucan$의 것이 아밀로펙틴보다 높았다.