• Title/Summary/Keyword: Alpha theory

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Preliminary Study to Develop the Korean Medical Pathologic Aging Scale and Korean Medical Pattern Identification for Dementia (한의학 병리적 노화 척도와 치매 한의학적 변증진단 개발 및 신뢰도 평가)

  • Lee, Go eun;Moon, Kwang Su;Kim, Nam Kwen;Chung, sun yong;Jung, In Chul;Kang, Hyung Won
    • The Journal of Korean Medicine
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    • v.38 no.3
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    • pp.111-123
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    • 2017
  • Objectives: To develop and investigate the reliability of the pathologic aging scale based on korean medical theory and korean medical pattern identification for dementia. Methods: We searched the textbook of korean neurophychiatry and Donguibogam and selected items through professional consensus. We compared between dementia(n=40) and normal elderly(n=38) and tested the reliability of two scales. Results: After professional consensus, we drafted the Korean Medical Pathologic Aging Scale(12 items, Likert 3 scale) and Korean Medical Pattern Identification for Dementia(4 patterns, 28 items, Likert 5 scale). On Korean Medical Pathologic Aging Scale, There is no significant difference between two groups. We had good internal consistency(Cronbach's alpha = 0.6) and test-retest reliability(r=0.631) but low inter-rater reliability(r=0.430). On Korean Medical Pattern Identification for Dementia, dementia patients diagnosed with Qi deficiency are significantly more than those in normal group. We had fairly good internal consistency(Cronbach's alpha = 0.574) and excellent test-retest(kappa= .800) and inter-rater reliability(kappa = .733). Conclusions: Korean Medical Pattern Identification for Dementia is appropriate for diagnosing korean medical pattern. But Korean Medical Pathologic Aging Scale isn't appropriate to discriminate dementia from normal elderly because of many subjective items. Therefore objective measurement of sensory dysfunction would be needed to measure pathologic aging based on korean medical theory.

Screening Tool for Anxiety Disorders: Development and Validation of the Korean Anxiety Screening Assessment

  • Kim, Yeseul;Park, Yeonsoo;Cho, Gyeongcheol;Park, Kiho;Kim, Shin-Hyang;Baik, Seung Yeon;Kim, Cho Long;Jung, Sooyun;Lee, Won-Hye;Choi, Younyoung;Lee, Seung-Hwan;Choi, Kee-Hong
    • Psychiatry investigation
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    • v.15 no.11
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    • pp.1053-1063
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    • 2018
  • Objective This study evaluated the psychometric properties of the Korean Anxiety Screening Assessment (K-ANX) developed for screening anxiety disorders. Methods Data from 613 participants were analyzed. The K-ANX was evaluated for reliability using Cronbach's alpha, item-total correlation, and test information curve, and for validity using focus group interviews, factor analysis, correlational analysis, and item characteristics based on item response theory (IRT). The diagnostic sensitivity and specificity of the K-ANX were compared with those of the Beck Anxiety Inventory (BAI) and Generalized Anxiety Disorder 7-item scale (GAD-7). Results The K-ANX showed excellent internal consistency (${\alpha}=0.97$) and item-total coefficients (0.92-0.97), and a one-factor structure was suggested. All items were highly correlated with the total scores of the BAI, GAD-7, and Penn State Worry Questionnaire. IRT analysis indicated the K-ANX was most informative as a screening tool for anxiety disorders at the range between 0.8 and 1.6 (i.e., top 21.2 to 5.5 percentiles). Higher sensitivity (0.795) and specificity (0.937) for identifying anxiety disorders were observed in the K-ANX compared to the BAI and GAD-7. Conclusion The K-ANX is a reliable and valid measure to screen anxiety disorders in a Korean sample, with greater sensitivity and specificity than current measures of anxiety symptoms.

Development of Preventive Self-Management Knowledge Related to Premature Labor (PSMK-PL) Scale for Women of Childbearing Age : An Item Response Theory Approach (가임 여성의 조기진통에 대한 예방적 자가관리 지식 측정 도구 개발: 문항반응이론 적용)

  • Kim, Sun-Hee;Lee, Yu-Jin
    • The Journal of the Korea Contents Association
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    • v.22 no.9
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    • pp.439-450
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    • 2022
  • Purpose: This study was to develop the Preventive Self-Management Knowledge related to Premature Labor (PSMK-PL) scale for women of childbearing age. Methods: Preliminary items were developed based on the literature and interview results of those who experienced premature labor. The online survey was conducted and the data of 250 women were analyzed using the DIMTEST and DETECT programs by applying the item response theory. Internal consistency reliability was analyzed with Cronbach's alpha (95% CI). Results: Among the 30 preliminary items, six items were deleted. The difficulty and discrimination of the 24 final three-dimensional scales were all acceptable, respectively. Cronbach's alpha (95% CI) was .89 (.87~.91). Conclusion: The PSMK-PL scale generally consisted of items with validity, and the reliability was acceptable.

Target Size of $(Na^++K^+)$-ATPase and $Na^+,\;K^+)$Pump of Human Erythrocytes (사람 적혈구막의 $(Na^++K^+)-ATPase/Na^+,\;K^+\;Pump$의 Target Size)

  • Hah, Jong-Sik;Jung, Chan Y.
    • The Korean Journal of Physiology
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    • v.19 no.1
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    • pp.15-23
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    • 1985
  • Previous biochemical studies indicate that $(Na^++K^+)-ATPase$ is composed of two subunits, ${\alpha}$ and ${\beta}$, in a form of ${\alpha}_2{\beta}_2$ with a molecular weight of approximately 300,000 daltons. There is also suggestive evidence that the $Na^+$, $K^+$ pump in human erythrocytes occurs in a complex with some glycolytic enzymes. We assessed here in situ assembly size of the $(Na^++K^+)-ATPase$ of human erythrocytes by applying classical target theory to radiation inactivation data of the ouabain-sensitive sodium flux and ATP hydrolysis of intact cells and ghosts. Cells(in the presence of cryoprotective agent) and ghosts were irradiated at $-45^{\circ}C$ to $-50^{\circ}C$ with an increasing dose of a 1.5 MeV electron beam, and after thawing, the pump and/or enzyme activities were assayed. Each activity measured was decreased as a simple exponential function of radiation dose, from which a radiation sensitive volume (target size) was calculated. When intact cells were used, the target size of both $(Na^++K^+)-ATPase$ and $Na^+$, $K^+$ pump was found to be approximately 600,000 daltons. This target size of the ATPase was reduced to approximately 325,000 daltons if the cells were pretreated with strophanthidin. When ghosts were used, the target size of the ATPase was again approximately 325,000 daltons. Our target size measurement suggests that, in intact cells, the $(Na^++K^+)-ATPase/Na^+,K^+$ pump exists either as a dimer of $(\alpha\beta)_2$ which is a functional unit or as a monomer of $(\alpha\beta)_2$ but in tight complex with other enzyme or enzymes. The results also suggest that this dimeric or heterocomplex association is dissociated during ghost preparation and strophanthidin treatment.

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Effects of the Story Sharing Activity on Conflicting Situations by Using Children's Story on the Theory of Mind and Peer Competence of Preschoolers (동화를 활용한 갈등상황 이야기나누기 활동이 유아의 마음이론과 또래유능성에 미치는 영향)

  • Lee, Mi Hee;Lee, Soon Bok
    • Human Ecology Research
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    • v.51 no.3
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    • pp.293-306
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    • 2013
  • The aim of this study is to examine the effects of the story sharing activity on-conflicting situations by the use of children's story on the theory of mind and peer competences of preschoolers so that appropriate teaching materials can be allocated for the actual preschool education site. The subjects of this study were 46 preschoolers under the age 4 at the attached kindergarten of P University in Pohang City, Gyeongbuk and in which 23 children among them were assigned to a test group and the other 23 to a control group. The collected data was analyzed by SPSS ver. 15.0 program and Cronbach's ${\alpha}$ coefficient was yielded to verify the reliability for each scale. The multivariate analysis of covariance (MANCOVA) was conducted. The analysis results are as follows. First, the story sharing activity on conflict situations by using children's story had a significant effect on the preschoolers' general appearance and actual task as sub-factors of the theory of mind, whereas no significant effects were found regarding the content change task and position change task. Second, the story sharing activity on conflict situations by using children's story had significant effect on the preschoolers' overall sensitivity, insecurity and pro-sociability as sub-factors of the peer competences, whereas no significant effects were found regarding the aggression, exclusivity and anti-sociability.

Mixed Micellar Properties of Sodium n-Octanoate(SOC) with n-Octylammonium Chloride(OAC) in Aqueous Solution (Sodium n-Octanoate(SOC)와 n-Octylammonium Chloride(OAC)의 혼합마이셀화에 관한 연구)

  • Lee, Byeong Hwan
    • Journal of the Korean Chemical Society
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    • v.46 no.6
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    • pp.495-501
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    • 2002
  • The critical micelle concentration(CMC) and the counterion binding constant(B) for the mixed micel-lization of sodium n-octanoate(SOC) with n-octylammonium chloride(OAC) were determined as a function of the overall mole fraction of $SOC({\alpha}_1).$ Various thermodynamic parameters($x_i$, $Y_i$, $C_i$, $${\alpha}_i^M$$, and $\Delta$$H_{mix}$) for the mixed micellization of the SOC/OAC systems have been calculated and analyzed by means of the equations derived from the nonideal mixed micellar model. The results show that there are great deviations from the ideal behavior for the mixed micellization of these systems. And other thermodynamic parameters(${\Delta}$$G^0_m$, ${\Delta}$$H^0_m$, and ${\Delta}$$S^0_m$) associated with the micellization of SOC,OAC, and their $mixture({\alpha}_1=0.5)$ have been also estimated from the temperature dependence of CMC and B values, and the significance of these parameters and their relation to the theory of the micelle formation have been considered and analyzed by comparing each other.

Constraints on dark radiation from cosmological probes

  • Rossi, Graziano;Yeche, Christophe;Palanque-Delabrouille, Nathalie;Lesgourgues, Julien
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.44.1-44.1
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    • 2015
  • We present joint constraints on the number of effective neutrino species $N_{eff}$ and the sum of neutrino masses ${\Sigma}m_{\nu}$, based on a technique which exploits the full information contained in the one-dimensional Lyman-${\alpha}$ forest flux power spectrum, complemented by additional cosmological probes. In particular, we obtain $N_{eff}=2.91{\pm}0.22$ (95% CL) and ${\Sigma}m_{\nu}$ < 0.15 eV (95% CL) when we combine BOSS Lyman-${\alpha}$ forest data with CMB (Planck+ACT+SPT+WMAP polarization) measurements, and $N_{eff}=2.88{\pm}0.20$ (95% CL) and ${Sigma}m_{\nu}$ < 0.14 eV (95% CL) when we further add baryon acoustic oscillations. Our results tend to favor the normal hierarchy scenario for the masses of the active neutrino species, provide strong evidence for the Cosmic Neutrino Background from $N_{eff}{\approx}3$($N_{eff}=0$ is rejected at more than $14{\sigma}$), and rule out the possibility of a sterile neutrino thermalized with active neutrinos (i.e., $N_{eff}=4$) - or more generally any decoupled relativistic relic with $${\Delta}N_{eff}{\sim_=}1$$ - at a significance of over $5{\sigma}$, the strongest bound to date, implying that there is no need for exotic neutrino physics in the concordance ${\Lambda}CDM$ model.

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Behaviors of Thick Antisymmetric Angle-Ply Laminate Using the Affine Transformation (유사 변환을 이용한 역대칭 앵글 플라이 적층 후판의 거동)

  • 이영신;양명석;나문수
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.15 no.1
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    • pp.28-40
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    • 1991
  • Affine transformation was used to analyze the bending, buckling and vibration behaviors of a thick antisymmetric angle-ply rectangular simply supported laminate. Introducing the generalized parameters, the comprehensive solutions are found. The generalized parameters are a generalized rigidity ratio ( $D^*1), a generalized Poisson's ratio (.epsilon.) and a principal rigidity ratio (.alpha.). Hence, the transverse deflection decreases, the uniaxial buckling load and the fundamental frequency increase with increasing $D^*1 and decreasing .alpha., but the effect of .epsilon. is negligible. With decreasing the thickness ratio, the results by the classical plate theory are more erroneous. The transverse deflection is minimum, the uniaxial buckling load and the fundamental frequency are maximum if the fiber angle is 45.deg., and number of plies is more than 4. The time and efforts can be saved to understand the behaviors of composite laminates because these results can be applied to another composite material easily.sily.

The Determination of Radon Progeny Concentration in Controlled Radon Environment (라돈을 제어하는 환경에서 라돈 자핵종의 농도 결정)

  • Seo, Kyung-Won;Lee, Byung-Kee
    • Journal of Radiation Protection and Research
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    • v.18 no.1
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    • pp.37-51
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    • 1993
  • A standard radon chamber and a radon generator adjusted by ventilation system which had used in this research were assumed to calculate theoretically the concentration of radon progeny using Jacobi model theory. On the one hand, the filter sampled from the radon standard chamber and the radon generator was measured and analysed by the alpha spectrometry method. It is clear that measured result shows a good agreement with theoretical result. Therefore, it is observed that this research can made a great contribution to more accurate internal dose assessment by alpha emission of radon progeny in indoor radon environment, and fast individual measurement and determination of concentration for radon progeny.

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Scaling theory to minimize the roll-off of threshold voltage for ultra fine MOSFET (미세 구조 MOSFET에서 문턱전압 변화를 최소화하기 위한 최적의 스켈링 이론)

  • 정학기;김재홍;고석웅
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.4
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    • pp.719-724
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    • 2003
  • In this paper, we have presented the simulation results about threshold voltage of nano scale lightly doped drain (LDD) MOSFET with halo doping profile. Device size is scaled down from 100nm to 40nm using generalized scaling. We have investigated the threshold voltage for constant field scaling and constant voltage scaling using the Van Dort Quantum Correction Model (QM) and direct tunneling current for each gate oxide thickness. We know that threshold voltage is decreasing in the constant field scaling and increasing in the constant voltage scaling when gate length is reducing, and direct tunneling current is increasing when gate oxide thickness is reducing. To minimize the roll off characteristics for threshold voltage of MOSFET with decreasing channel length, we know $\alpha$ value must be nearly 1 in the generalized scaling.