• Title/Summary/Keyword: Aging processes

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Superoxide Anion Radical: Principle and Application (슈퍼옥사이드 음이온 라디칼 화학과 응용)

  • Kwon, Bum Gun;Yoon, Jeyong
    • Applied Chemistry for Engineering
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    • v.20 no.6
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    • pp.593-602
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    • 2009
  • For a long time, there is much interest in the superoxide anion radical as one of reactive oxygen species (ROS) not only in the basic research field of chemistry and physics but also in the life science (or biotechnology). Recently, it is becoming ever more vital since the toxic property of nanomaterials as well as advanced oxidation processes (AOP) frequently employed for controlling pollutants are connected with the formation of superoxide anion radicals. Despite many researches on superoxide anion radical, the quantitative information of its presence and its detailed reaction mechanism in aqueous environments remains largely unclear, causing the controversy and confusion. In this review paper, we attempted to summarize the physicochemical property, mechanisms, and applications of superoxide anion radical. In addition, we briefly incorporated the important application of superoxide anion radical in AOP, nanomaterials, and life science (or biotechnology).

An Algorithm Study to Detect Mass Flow Controller Error in Plasma Deposition Equipment Using Artificial Immune System (인공면역체계를 이용한 플라즈마 증착 장비의 유량조절기 오류 검출 실험 연구)

  • You, Young Min;Jeong, Ji Yoon;Ch, Na Hyeon;Park, So Eun;Hong, Sang Jeen
    • Journal of the Semiconductor & Display Technology
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    • v.20 no.4
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    • pp.161-166
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    • 2021
  • Errors in the semiconductor process are generated by a change in the state of the equipment, and errors usually arise when the state of the equipment changes or when parts that make up the equipment have flaws. In this investigation, we anticipated that aging of the mass flow controller in the plasma enhanced chemical vapor deposition SiO2 thin film deposition method caused a minute flow rate shift. In seven cases, fourier transformation infrared film quality analysis of the deposited thin film was used to characterize normal and pathological processes. The plasma condition was monitored using optical emission spectrometry data as the flow rate changed during the procedure. Preprocessing was used to apply the collected OES data to the artificial immune system algorithm, which was then used to process diagnosis. Through comparisons between datasets, the learning algorithm compared classification accuracy and improved the method. It has been confirmed that data characterized as a normal process and abnormal processes with differing flow rates may be discriminated by themselves using the artificial immune system data mining method.

Development of Deep Learning-based Automatic Classification of Architectural Objects in Point Clouds for BIM Application in Renovating Aging Buildings (딥러닝 기반 노후 건축물 리모델링 시 BIM 적용을 위한 포인트 클라우드의 건축 객체 자동 분류 기술 개발)

  • Kim, Tae-Hoon;Gu, Hyeong-Mo;Hong, Soon-Min;Choo, Seoung-Yeon
    • Journal of KIBIM
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    • v.13 no.4
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    • pp.96-105
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    • 2023
  • This study focuses on developing a building object recognition technology for efficient use in the remodeling of buildings constructed without drawings. In the era of the 4th industrial revolution, smart technologies are being developed. This research contributes to the architectural field by introducing a deep learning-based method for automatic object classification and recognition, utilizing point cloud data. We use a TD3D network with voxels, optimizing its performance through adjustments in voxel size and number of blocks. This technology enables the classification of building objects such as walls, floors, and roofs from 3D scanning data, labeling them in polygonal forms to minimize boundary ambiguities. However, challenges in object boundary classifications were observed. The model facilitates the automatic classification of non-building objects, thereby reducing manual effort in data matching processes. It also distinguishes between elements to be demolished or retained during remodeling. The study minimized data set loss space by labeling using the extremities of the x, y, and z coordinates. The research aims to enhance the efficiency of building object classification and improve the quality of architectural plans by reducing manpower and time during remodeling. The study aligns with its goal of developing an efficient classification technology. Future work can extend to creating classified objects using parametric tools with polygon-labeled datasets, offering meaningful numerical analysis for remodeling processes. Continued research in this direction is anticipated to significantly advance the efficiency of building remodeling techniques.

Ferulate, an Active Component of Wheat Germ, Ameliorates Oxidative Stress-Induced PTK/PTP Imbalance and PP2A Inactivation

  • Koh, Eun Mi;Lee, Eun Kyeong;Song, Chi Hun;Song, Jeongah;Chung, Hae Young;Chae, Chang Hoon;Jung, Kyung Jin
    • Toxicological Research
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    • v.34 no.4
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    • pp.333-341
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    • 2018
  • Ferulate is a phenolic compound abundant in wheat germ and bran and has been investigated for its beneficial activities. The aim of the present study is to evaluate the efficacy of ferulate against the oxidative stress-induced imbalance of protein tyrosine kinases (PTKs), protein tyrosine phosphatases (PTPs), and serine/threonine protein phosphatase 2A (PP2A), in connection with our previous finding that oxidative stress-induced imbalance of PTKs and PTPs is linked with proinflammatory nuclear factor-kappa B $(NF-{\kappa}B)$ activation. To test the effects of ferulate on this process, we utilized two oxidative stress-induced inflammatory models. First, YPEN-1 cells were pretreated with ferulate for 1 hr prior to the administration of 2,2'-Azobis(2-methylpropionamidine) dihydrochloride (AAPH). Second, 20-month-old Sprague-Dawley rats were fed ferulate for 10 days. After ferulate treatment, the activities of PTKs, PTPs, and PP2A were measured because these proteins either directly or indirectly promote $NF-{\kappa}B$ activation. Our results revealed that in YPEN-1 cells, ferulate effectively suppressed AAPH-induced increases in reactive oxygen species (ROS) and $NF-{\kappa}B$ activity, as well as AAPH-induced PTK activation. Furthermore, ferulate also inhibited AAPH-induced PTP and PP2A inactivation. In the aged kidney model, ferulate suppressed aging-induced activation of PTKs and ameliorated aging-induced inactivation of PTPs and PP2A. Thus, herein we demonstrated that ferulate could modulate PTK/PTP balance against oxidative stress-induced inactivation of PTPs and PP2A, which is closely linked with $NF-{\kappa}B$ activation. Based on these results, the ability of ferulate to modulate oxidative stress-related inflammatory processes is established, which suggests that this compound could act as a novel therapeutic agent.

Inhibitory Effect of Rosa multiflora hip Extract on UVB-induced Skin Photoaging in Hs68 Fibroblasts (자외선으로 유도된 Hs68 섬유아세포의 노화 반응에 대한 영실추출물의 억제 효능)

  • Park, Ji-Eun;Kim, Hyoung Ja;Kim, Su-Nam;Kang, Seung Hyun;Kim, Youn Joon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.4
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    • pp.351-359
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    • 2015
  • Acute and chronic ultraviolet (UV) irradiation triggers severe skin photoaging processes, which directly disrupt the normal three-dimensional integrity of skin. UV light stimulates the expression of matrix metalloproteinases (MMPs) which degrade constituents of extracellular matrix (ECM) proteins. These MMPs reduce collagen synthesis and decrease skin elasticity and integrity, resulting in wrinkle formation. In this study, we identified Rosa multiflora hip extract (RME) as an effective anti-photoaging ingredient. First, cell proliferation activity of RME was verified using Hs68 human dermal fibroblast cell line. RME downregulated MMPs expression through the inhibition of activator protein (AP)-1. In addition, type I and IV collagen expressions were increased with RME treatment and UVB-induced inflammatory responses were also reduced after RME treatment. In conclusion, R. multiflora hip extract may effectively improve UVB-induced skin aging and wrinkle formation which may provide as an anti-aging, anti-wrinkle, and anti-inflammation ingredient in cosmetic industry.

Vocational Adjustment in Elderly Men Who Chose a Creative Occupation after Retirement (퇴직 후 창의적 직업을 선택한 남성 노인의 직업적응 경험)

  • Lee, Hak Seung;Jun, Hey Jung
    • 한국노년학
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    • v.39 no.2
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    • pp.261-284
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    • 2019
  • This study examines the vocational adjustment experiences of elderly men who chose a creative occupation after retirement. The aims are to understand the related meanings and to provide specific empirical data on the elderly who hope to start a creative occupation. Five men aged 65 years or older who chose a creative occupation after retirement were enrolled in the study. Data were collected through in-depth interviews with the participants. The collected data were qualitatively analyzed, and a total of 7 categories, 25 subcategories, and 132 concepts were identified. The seven categories were "challenge led by a sense of freedom," "reflection of the need for 'fun,'" "difficulties and limitations felt by a non-expert," "concerns and effort to afford the increasing expenses," "joy for accomplishment," "ways to utilize my creativity," and "reward from increased social participation." The participants felt that adjusting to a creative occupation was a process by which their potential creativity was expressed. They felt the joy of working that they had not felt before, and the series of processes by which they overcame difficulties during work and increased their social participation were in line with the goals of creative aging. In order to help older adults in Korea to choose and adjust to creative occupations in their older adulthood, there is a need for creative-occupation-related education prior to retirement and for various policies and practical efforts that consider the change of social environment. Furthermore, our findings suggest that choosing a creative occupation after retirement is an effective measure for promoting successful aging among the elderly in Korea.

Men's and women's body types in the global garment sizing systems

  • Chun, Jongsuk
    • The Research Journal of the Costume Culture
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    • v.20 no.6
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    • pp.923-936
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    • 2012
  • Apparel companies define their target customers to integrate consumers' needs into their product development processes. The sizing standards play a significant role in ready-to-wear garment business. Consumers' body build and sizes are different according to gender, age, and body type. The consumers' morphological feature of the one geographical area has changed with immigration, aging, and lifestyle change. In this study the way of defining body types in the standard garment sizing systems published in USA., UK, Germany, Japan, and Korea were compared. The results of this study show that most of the systems classified the body types by the index value. The chest-waist drop value was used for men's body type classification. Women's body types were defined by hip proportion. The hip-bust drop value was used for it. German and European garment sizing systems provide a wide range of men's body types. US men's garment sizes are developed for very conservative body type. US women's garment sizing system has had clearly defined women's body types. The Misses body types projected in the US garment sizing system had changed as women's waist girth got bigger compared to the past. In 2011 the US Misses sizes were divided into Curvy Misses size and Straight Misses size by the hip-waist drop value. The Curvy Misses sizes have smaller waist girth and larger hip girth than the Straight Misses sizes.

Reliability Evaluation and failure Analysis for High Voltage Ceramic Capacitor (고압 커패시터의 고장분석과 신뢰성 평가)

  • 김진우;송옥병;신승우;이희진;신승훈;유동수
    • Proceedings of the Korean Reliability Society Conference
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    • 2001.06a
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    • pp.337-337
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    • 2001
  • High voltage ceramic capacitors are widely applied in power electronic circuits, such as filters, snubbers, and resonant circuits, due to their excellent features of high voltage endurance and low aging. This paper presents a result of failure analysis and reliability evaluation for high voltage ceramic capacitors. The failure nodes and failure mechanisms were identified in order to understand the failure physics in a component. The causes of failure mechanisms for zero resistance phenomena under withstanding voltage test in high voltage ceramic capacitors molded by epoxy resin were studied by establishing an effective closed-loop failure analysis. Also, the condition for dielectric breakdown was investigated. Particular emphasis was placed on breakdown phenomena at the ceramic-epoxy interface. The validity of the results in this study was confirmed by the results of accelerated testing. Thermal shock test as well as pressure cooker test for high voltage ceramic capacitor mounted on a magnetron were implemented. Delamination between ceramic and epoxy, which, might cause electrical short in underlying circuitry, can occur during curing or thermal cycling. The results can be conveniently used to quickly identify defective lots, determine mean time to failure (MTTF) of each lot at the level of Inspection, and detect major changes in the vendors processes.

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Antioxidant enzymes as redox-based biomarkers: a brief review

  • Yang, Hee-Young;Lee, Tae-Hoon
    • BMB Reports
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    • v.48 no.4
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    • pp.200-208
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    • 2015
  • The field of redox proteomics focuses to a large extent on analyzing cysteine oxidation in proteins under different experimental conditions and states of diseases. The identification and localization of oxidized cysteines within the cellular milieu is critical for understanding the redox regulation of proteins under physiological and pathophysiological conditions, and it will in turn provide important information that are potentially useful for the development of novel strategies in the treatment and prevention of diseases associated with oxidative stress. Antioxidant enzymes that catalyze oxidation/reduction processes are able to serve as redox biomarkers in various human diseases, and they are key regulators controlling the redox state of functional proteins. Redox regulators with antioxidant properties related to active mediators, cellular organelles, and the surrounding environments are all connected within a network and are involved in diseases related to redox imbalance including cancer, ischemia/reperfusion injury, neurodegenerative diseases, as well as normal aging. In this review, we will briefly look at the selected aspects of oxidative thiol modification in antioxidant enzymes and thiol oxidation in proteins affected by redox control of antioxidant enzymes and their relation to disease. [BMB Reports 2015; 48(4): 200-208]

Chemical Properties of Mineral Surfaces and Metal Ion Sorption: A Review (광물표면의 화학적 특성과 금속이온 수착의 고찰: A Review)

  • Yoon, Soh-Joung
    • Economic and Environmental Geology
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    • v.45 no.2
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    • pp.205-215
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    • 2012
  • Metal ions, toxic or potentially toxic to biota and human beings, can be immobilized by sorption onto the mineral surfaces in soils and sediments. This article briefly explains theories regarding the chemical properties of mineral surfaces to sorb metal ions and processes of extended X-ray absorption fine structure (EXAFS) analysis for sorption study, and reviews atomic-scale findings on metal sorption on mineral surfaces. The theoretical understanding on the chemistry of mineral surfaces and metal sorption is fundamental to the proper analysis of the atomic-scale spectroscopy to determine the sorption phases. Atomic-scale findings on metal sorption phases discussed here include co-precipitation, ternary complexation, aging effects, and desorption possibilities, as well as outer-sphere complexation, inner-sphere complexation, and surface precipitation.