• Journal of Nutrition and Health
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• v.35 no.3
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• pp.279-290
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• 2002

This study was performed to assess age-related changes in DNA damage and antioxidative capacity in 4, 8, 12, 16, 20, and 24 months old Sprague-Dawley male rats. The following were measured the degree of oxidative DNA damage as indicated by levels of 8-hydroxy-2'-deoxyguanosine (80HdG) in the kidney ; the peroxidized lipid concentrations in the plasma and the liver, as indicated by the levels of thiobarbituric acid reactive substances (TBARS); and the levels of antioxidant enzyme activities in the erythrocytes and the liver. Both body weight (BW) and epididymal fat pad (EFP) weight per BW increased with age until 16 months, then decreased slightly from 20 to 24 months. However, the weights of the liver, kidney and spleen per BW decreased with age. Concentrations of 8-OHdG in the kidney increased with age, only slightly front 4 to 16 months, and then markedly from 16 to 24 months. TBARS concentrations in the plasma and liver were shown to increase with age, being lowest in the 4 month-old group and highest in the 24 month-old group. Superoxide dismutase (SOD) activity in the erythrocytes increased with age Catalase activity in the erythrocytes increased from 4 to 16 months, then decreased from 20 to 24 months. Glutathione peroxidase (GSH-Px) activity in the erythrocytes showed no age-related change. Liver SOD activity decreased with age, particularly from 16 to 20 months, but catalase and GSH-Px activities in the liver showed no significant changes. These results showed that during the normal aging of SD rats, DNA damage in the kidney and TBARS concentrations in the plasma and liver increased with age, particularly after 16 months, and the imbalance of antioxidative enzyme activities in the erythrocytes accelerated with age.

• The Research Journal of the Costume Culture
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• v.15 no.1 s.66
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• pp.37-57
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• 2007

The purpose of this study was to analyze the body measurements of boys and girls at puberty and to provide the fundamental data for pubescent apparel manufacturers to produce clothing that reflect their physical characteristics. A total of 549 boys and 529 girls aged between 10 and 14 were measured in the capital area from March 4 to April 3, 2004. Data were collected from 35 anthropometric items and 12 photographic items per a person. SPSS Ver. 12 program was used in data analysis including means, standard deviation, t-test and Duncan test. The main results of this study were as follows. They showed the significant difference of their growth in accordance with the increase of their ages. There were also the difference between boys and girls. As for height and length items, boys showed a slow growth at the age of $10{\sim}11\;and\;12{\sim}13$. Those at the age of $11{\sim}12\;and\;13{\sim}14$ showed rapid growth. That is, an active growth was followed by a slow growth and that phenomenon repeatedly occurred. On the other hand, girls showed remarkable growth at the age $10{\sim}11$ and the growth rate gradually slowed down afterward. Regarding circumference items, boys at the age of $11{\sim}12\;and\;13{\sim}14$ showed remarkable growth. This results showed that boys at the age of $11{\sim}12$ had vertical growth and horizontal growth at the same time and for those at the age of $13{\sim}14$, growth was more conspicuous in horizontal direction. Meanwhile, for girls, the growth rate was high at the age of $11{\sim}12$, somewhat later than the age of the growth of height and length. As for breadth-related items and depth-related items, for both sexes two items grew steadily throughout the ages, breadth-related items showed a higher growth rate than that of depth-related items. This study analyzed the body measurements of pubescent boys and girls and the results showed that, for boys, an active physical growth took place at the age of 13 according to previous studies, but the findings of this study suggested that the phenomenon now occurred at the age of $11{\sim}12$, which proved that physical growth took place earlier than before. Also, an active growth was followed by a slow growth. Girls at puberty showed remarkable growth of height at the age of $10{\sim}11$ that is consistent with previous studies and then showed horizontal growth at the age of around 12, having a voluminous body shape.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.26 no.2
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• pp.131-138
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• 2013

The high damping rubber bearings contributed to reduce a seismic force transmitted to upper structures, the material properties of rubber changes with time and the rubber with age-related degradation can affect the seismic response of structures and equipments. Therefore the seismic response of structure considering age-related degradation of isolators should be evaluated. In this paper, the stiffness and damping for isolators were defined using the aging data proposed by other researchers. The reactor containment building and the auxiliary building were selected to conduct the nonlinear analysis and the natural frequency, maximum responses, floor response spectrum(FRS) were evaluated with time using the four earthquakes with different frequency contents. According to the analysis results, the seismic responses are increased by the age-related degradation of isolators and the detail inspections should be conducted up to 20 years because it was presented that the change of FRS was high during this period.

• Korean Journal of Health Education and Promotion
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• v.5 no.2
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• pp.52-62
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• 1988

The purpose of this study was to improve the motivation for prevention of adult chronic disease through identifying the relationship between health awareness and health behavior. These data was based on the survey of 524 men, This study employed 90 questions, related to general cheracteristics, health awareness, health behavior, dietary habit, mass media utilizing health information, The data were analyzed by using t-test, ANOVA, Contingency-Coefficient, Duncan's multiple range test. The result of this study revealed the follows: 1. The contingency coefficient between health awareness and health behavior showed that total(C=0.3272), 30-39 age group(C=3949), 40-49 age group(C=0.3978), which(C.) mean higher scores, had a [used to visit whenever they were ill], that 50-59 age group(C=0.4165) demonstrate higher score concerned with [Smoking]. 2, The general dietary habit related to statistically significant difference in men's age, educational status, income, economic status, job, concern of adult chronic disease(p<0.01). 3. The general dietary habit related to statistically significant difference in cancer patients arrounding them, knowledge of diabetes, hypertensiom and cancer (p<0.01). 4, Dietary habit for preventing obesity related to statistically significant difference in men's age, income(p<0.05). 5, Dietary habit for preventing obesity related to statistically significant difference in sensitivity of diabetes, hypertension and knowledge of diabetes, cancer(p<0.01). In conclusion, health education which were emphasis of health behavior formation is reguired.

• Journal of Life Science
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• v.33 no.9
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• pp.736-745
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• 2023

Aging is a complex biological process characterized by a gradual decline in cellular and physiological functions. This natural process is associated with age-related diseases, including Alzheimer's disease, atherosclerosis, and hypogonadism, which are significant health concerns among older individuals and can significantly impact their quality of life. Researchers have found that epigenetic markers play a crucial role in regulating aging and age-related diseases. Epigenetic markers are heritable gene expression alterations that do not change in the DNA sequence. This review focuses on the involvement of various epigenetic marks, such as RNA methylation, DNA methylation, and microRNAs (miRNAs), in regulating gene expression patterns associated with age-related diseases, such as Alzheimer's disease, atherosclerosis, and hypogonadism. These epigenetic alterations can lead to the dysregulation of specific genes and signaling pathways, contributing to the development and progression of Alzheimer's disease, atherosclerosis, and hypogonadism. Understanding the molecular mechanisms behind these epigenetic modifications is essential for both the aging population and individuals seeking ways to promote overall well-being. By gaining deeper insights into how epigenetic marker alteration occurs during aging and age-related diseases, researchers can potentially develop targeted therapeutic strategies to alleviate the impact of these conditions and improve the quality of life for older individuals.

• Journal of Families and Better Life
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• v.22 no.5
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• pp.47-58
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• 2004

In this article the relations between demographics, variables related to credit card, flow and compulsive buying tendency were explored. The survey data collected from 318 university students. The results of regression analysis showed that older students were related to the greater number of card. The greater allowance and number of card were related to the greater average card expenditure per month. Female, younger and the greater average card expenditure per month were related to greater flow. And younger students tended to be more compulsive buying tendency than older students. The greater allowance and flow were related to greater compulsive buying tendency. The results of path analysis showed that the age, allowance and flow influenced on compulsive buying tendency direct. Also age and allowance influenced on compulsive buying tendency direct and indirect.

• Korean Journal of Family Social Work
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• no.59
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• pp.27-53
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• 2018

The objective of this study was to investigate the influence of family-related factors and age-friendly environment on intergenerational interaction in middle-aged group and the older adult group. Based on the results, this study is to suggest countermeasures for decreasing intergenerational interaction with the population aging. This study analyzed 260 sample participants aged from 45 to 64 and 399 sample participants aged 64 and more, categorizing them into middle-aged group and the older adult group respectively. The sample participants were taken from '2014 Survey on the Aged Society' and had at least one adult child aged over 18 at the time of participation. In order to identify the relationship between five sub-dimensions related to family, age-friendly environment and intergenerational interaction within the family in two age groups, t-test and multiple regression analysis were used. As a result, both two family-related factors had positive correlation with intergenerational interaction within the family. However, affective solidarity showed a higher significance in the middle-aged group and familism showed a higher significance in the older adult group. Among the sub-dimensions related to age-friendly environment, only personal opinion on age integration showed significance in the older adult group. This study provides several implications from the results.

• Korean Journal of Health Education and Promotion
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• v.10 no.2
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• pp.73-85
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• 1993

It is necessary to understand the relationship between socio-cultural elements and smoking, alcohol, and marijuana use behaviors in order to plan public health policy or health promotion program of Mexican Americans. Demographic, socioeconomic status, and acculturation are variables which reflect mechanisms socialization influences these behavior patterns among this population. Thus, this study investigates the prevalence of addictive behaviors and individual differences on addictive behaviors related to variables of acculturation, age, gender, education, and income. And the interrelations among addictive behaviors are also examined. The analyses used data for Mexican Americans from the U.S. Hispanic Health and Nutrition Examination Survey conducted from July 1982 through December 1984 by the National Center for Health Statistics. ANOVA and correlation coefficients were used for this study. This study found that there are gender differences among addictive behaviors in their prevalence. Both males' and females' alcohol and marijuana use behaviors are positively related to the acculturation. Females' smoking behavior is positively related to acculturation while males' smoking is negatively related to it. Income and education are negatively related to males' smoking and positively related to males' alcohol behavior. However, males' marijuana behavior is not related to income. Females' smoking behaviors is not significantly related income and education. Education and income are positively related to marijuana behavior among females. Age is related to all three addictive behaviors among both gender. Age is negatively related to both males' and females' marijuana use behavior. Interrelation between smoking and marijuana use behavior is not significant among males. However, interrelations between alcohol and marijuana use behavior and between alcohol and smoking are significant among both genders. Females' smoking and marijuana use behavior is also significantly related.

• Journal of Preventive Medicine and Public Health
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• v.45 no.2
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• pp.70-77
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• 2012

Objectives: Identify the characteristics related to the suicide rates in rural and urban areas of Korea and discover the factors that influence the suicide rate of the rural and urban areas. Methods: Using the data on causes of death from 2006 to 2008, the suicide rates were calculated and compared after age-standardization based on gender, age group and urbanicity. And, in order to understand the factors that influence suicide rate, total 10 local characteristics in four domains - public service, social integration, residential environment, and economic status - were selected for multiple regression analysis. Results: The suicide rates were higher in men than women, in rural areas than urban, and in older people than the younger. Generally, although there were variations according to age group and urbanicity, suicide rates were significantly related to residential environment and regional economic status but not related to regional welfare spending and social integration. In addition, the population over the age of 65 years, only regional economic status has significantly influence on their suicide rates. Conclusions: The influence of characteristics of regions on suicide rate is various by age-group, gender, and urbanicity. Therefore, in order to lower suicide rate and reduce the gap between regions, various approaches must be adopted by taking into account the socioeconomic characteristics of the regions.

• Journal of the Korea Convergence Society
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• v.8 no.10
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• pp.273-279
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• 2017

Purpose: This study was conducted to identify factors associated with cataract and age-related macular degeneration in elders. Methods: In total, 341,588 men(44.18%,) and women(61.887%), aged over 60, were recruited from Korean National Health Insurance Service-Senior(2002-2013). We also analysed the factors which determine the prevalence of contract (ICD-10: H25) and age-related macular degeneration(ICD-10: H353) using Cox proportional hazard regression model Results: The subjects who were women, in older age, the group of higher income level, with hypertension, with heart disease, and with diabetes, the prevalence of both contract and age-related macular were increased(p<0.0001). Conclusion: The prevalence of contract and age-related macular degeneration were higher in old age of Korean who has chronic diseases such as hypertension, heart disease, and diabetes. The management of chronic diseases are essentially required in elderly for more healthy eye in aged society.