• Title/Summary/Keyword: Adult male

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Expression of Nesfatin-1/NUCB2 in Fetal, Neonatal and Adult Mice

  • Chung, Yiwa;Jung, Eunhye;Kim, Heejung;Kim, Jinhee;Yang, Hyunwon
    • Development and Reproduction
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    • v.17 no.4
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    • pp.461-467
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    • 2013
  • Nesfatin-1/NUCB2, which is associated with the control of appetite and energy metabolism, was reported for the first time to be expressed in the hypothalamus. However, recent studies have shown that nesfatin-1/NUCB2 was expressed not only in the hypothalamus, but also in various tissues including digestive and reproductive organs. We also demonstrated that nesfatin-1/NUCB2 was expressed in the reproductive organs, pituitary gland, heart, lung, and gastrointestinal tract of the adult mouse. However, little is known about nesfatin-1/NUCB2 expression in fetal and neonatal mice. Therefore, we examined here the distribution of nesfatin-1/NUCB2 in various organs of fetal and neonatal mice and compared them with the distribution in adult mice. As a result of immunohistochemical staining, nesfatin-1/NUCB2 protein was expressed relatively higher in the lung, kidney, heart, and liver compared to other organs in the fetus. Western blot results also showed that nesfatin-1/NUCB2 protein was detected in the lung, kidney, heart, and stomach. Next, we compared the expression levels of nesfatin-1/NUCB2 mRNA in the fetus and neonate with the expression levels in both male and female adult mice. The expression levels in heart, lung, stomach, and kidney were higher compared with other organs in fetal and neonatal mice and in both male and female adult mice. Interestingly, the expression of nesfatin-1/NUCB2 mRNA in the kidney was dramatically increased in male and female adult mice compared to fetal and neonatal mice. These results indicate that nesfatin-1/NUCB2 may regulate the development and physiological function of mouse organs. In the future, we need more study on the function of nesfatin-1/NUCB2, which is highly expressed in the heart, lung, and kidney during mouse development.

The Effects of Caffeine on the Long Bones and Testes in Immature and Young Adult Rats

  • Kwak, Yoojin;Choi, Hyeonhae;Roh, Jaesook
    • Toxicological Research
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    • v.33 no.2
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    • pp.157-164
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    • 2017
  • This study was to evaluate the age-dependent effects of caffeine exposure on the long bones and reproductive organs using male rats. A total of 15 immature male rats and 15 young adult male rats were allocated randomly to three groups: a control group and two groups fed caffeine with 120 and 180 mg/kg/day for 4 weeks. Exposure to caffeine at either dose significantly reduced body weight gain; a proportional reduction in muscle and fat mass in immature animals, whereas a selective reduction in fat mass with relatively preserved muscle mass in young adult animals. The long bones of immature rats exposed to caffeine were significantly shorter and lighter than those of control animals along with decreased bone minerals. However, there was no difference in the length or weight of the long bones in young adult rats exposed to caffeine. Exposure to caffeine reduced the size and absolute weight of the testes significantly in immature animals in comparison to control animals, but not in young adult animals exposed to caffeine. In contrast, the adrenal glands were significantly heavier in caffeine-fed young adult rats in comparison to control animals, but not in caffeine-fed immature rats. Our results clearly show that the negative effects of caffeine on the long bones and testes in rats are different according to the age of the rat at the time of exposure, and might therefore be caused by changes to organ sensitivity and metabolic rate at different developmental stages. Although the long bones and testes are more susceptible to caffeine during puberty, caffeine has negative effects on body fat, bone minerals and the adrenal glands when exposure occurs during young adulthood. There is a need, therefore, to educate the public the potential dangers of caffeine consumption during puberty and young adulthood.

LOCALIZATION OF MERCURY COMPOUND IN TESTIS, EFFERENT DUCTULE AND EPIDIDYMIS OF THE ADULT MOUSE

  • Cho, Hyun-Wook;Yee, Sung-Tae;Rex A. Hess
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.118-118
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    • 2001
  • To find out localization of mercury in male reproductive system, adult male mice were injected subcutaneously with methyl mercuric chloride (1mg/mouse) once per week for 20, 40 and 70 days. The experimental periods later, animals were sacrificed by transcardial perfusion and organs were removed, dehydrated, and embedded in paraffin.(omitted)

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Effects of Short-Term Treatment with Estrogen Receptor Agonist on Morphological Changes in Reproductive Organs of Adult Male Mice

  • Choi, Hayana;Mo, Yun Jeong;Lee, Mi-Kyung;Choe, Eun Sang;Yee, Sung Tae;Cho, Hyun Wook
    • Applied Microscopy
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    • v.46 no.4
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    • pp.193-200
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    • 2016
  • Male reproductive organs are strongly affected by estrogen signaling mediated via the estrogen receptor. In this study, propyl pyrazole triol (PPT), an estrogen receptor alpha agonist, was subcutaneously injected in adult male mice every 2 days for a total duration of 8, 16, or 24 days. Histological changes in the reproductive organs, including the testes, efferent ductules, and epididymides, were observed. The weight of the reproductive organs decreased in the PPT group. In addition, the diameter of the seminiferous tubules decreased in the PPT group compared with the control group. The epithelial cell height decreased in the initial segment of the epididymis, whereas the luminal diameter increased in the efferent ductules of the PPT group. PPT induced irregular morphology of stereocilia in the luminal region of the initial segment. Therefore, PPT treatment at high concentrations had inhibitory effects in the reproductive organs of adult male mice. These findings suggest that short-term treatment with estrogen receptor agonist causes histological changes in the testes, efferent ductules, and epididymis, which are similar to those caused by estrogen receptor antagonist treatment. Therefore, the estrogen receptor may have functional roles in male reproductive organs, implying that treatment with an estrogen receptor agonist can affect male fertility.

Male-Specific Protein (MSP) of Wax Moth - a New Member of JHBP Family

  • Jikhyon Han;Lee, Chang-Seok;Yun, Chi-Young;Kim, Hak-Ryul
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.04a
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    • pp.81-81
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    • 2003
  • Male-specific protein (MSP) is a soluble protein which is accumulated in high amounts In the hemolymph and other organs of adult male wax moth. The MSP was purified from adult male wax moth by gel filtration and reversed Phase column chromatography, and its amino acid sequence was determined. Three internal amino acid sequences of MSP were obtained by the in-gel digestion method using trypsin because of its blocked N-terminus. (omitted)

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The Effects of Adult Children Related Variables on Life Satisfaction among the Rural Elderly Male and Female (농촌 여성노인과 남성노인의 생활만족도에 영향을 미치는 성인자녀 관련변인에 관한 연구)

  • 김은경
    • Journal of Families and Better Life
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    • v.20 no.4
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    • pp.27-36
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    • 2002
  • This paper examines the effects of children related variables on the life satisfaction of the rural elderly. Data for this study were based on a study of 203 elderly people residing in Kyungnam, Korea. Elderly male achieved higher scores in life satisfaction than their female counterparts. Demographic variables, except for subjective financial status, failed to account for the significant variance in life satisfaction. There were gender differences on the effects of children related variables on life satisfaction. Number of children was significantly associated with the life satisfaction of the male elderly. For the female elderly, affectional solidarity and associational solidarity were significant Predictors to their life satisfaction. Associational solidarity had the strongest effect on life satisfaction of both male and female elderly. The results from this study suggest the relative importance of children related variables to the rural elderly.

A Research on Purchase Behavior and Fit of Men′s Ready-made Suit for Koran Adult Men (성인 남성의 신사복 구매행동과 맞음새에 관한 조사 연구)

  • 박진영;손희순
    • The Research Journal of the Costume Culture
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    • v.9 no.1
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    • pp.45-60
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    • 2001
  • The purpose of this research is to offer basic data for the study of men's suit by investigating purchase behavior and fit of men's ready-made suit for Koran adult men. The subjects were male who aged 25∼39 and resided in Seoul, Kyunggi and Chungnam regions. The results of the research are summarized as the following : 1. Male consumers purchase suit most frequency at department, specially stores. As the consumers grow older dependency on their spouses'opinion for purchase decision increases. The standards of purchasing are stated to e design, price and color. 2. the male consumers are generally knowledgeable about the current sizing system. Yet, the knowledge is confused with the pst and present systems. 3. When the male consumers purchase, they consider mainly for the fit of th d\\body part are shoulders for the jacket and waist, hip for the pants. 4. The attitude to toward the combination of sizes for the jacket is comparatively satisfaction than pants. Specially, most negative part of jacket is the length of sleeve.

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Microbiome of Haemaphysalis longicornis Tick in Korea

  • Kim, Myungjun;Kim, Ju Yeong;Yi, Myung-hee;Lee, In-Yong;Yong, Dongeun;Jeon, Bo-Young;Yong, Tai-Soon
    • Parasites, Hosts and Diseases
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    • v.59 no.5
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    • pp.489-496
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    • 2021
  • Ticks can transmit pathogenic bacteria, protozoa, and viruses to humans and animals. In this study, we investigated the microbiomes of Haemaphysalis longicornis according to sex and life stages. The Shannon index was significantly higher for nymphs than adult ticks. Principal coordinates analysis showed that the microbiome composition of female adult and male adult ticks were different. Notably, Coxiella-like bacterium (AB001519), known as a tick symbiont, was found in all nymphs and female adult ticks, but only one out of 4 male adult ticks had Coxiella-like bacterium (AB001519). In addition, Rickettsia rickettsii, Coxiella burnetii, and Anaplasma bovis were detected in this study.

A Study About Adult Character Portrayed in Picture Books (그림책에 그려진 성인 등장인물에 대한 연구)

  • Jang, Hae Mi;Hyun, Eun Ja
    • Korean Journal of Child Studies
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    • v.29 no.4
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    • pp.15-26
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    • 2008
  • This study analyzed the portrayal of adult characters in 176 picture books published in Korea by variables of character's external condition(sex, name, age and occupation), type(3-dimensional or flat), conflicts, and image. Standards for analysis of the picture books were devised by the researcher. Results showed that (1) adult male characters appeared much more frequently than female; they appeared most often without names and in order of older, middle aged, young adult. They appeared most often without occupations. (2) 3-dimensional characters appeared much more than flat ones. (3) Adult conflict situations were rare and were mostly interpersonal. They often resolved their conflicts by themselves. (4) The 20 kinds of images of the adult characters were mostly humorous, warm-hearted and attentive.

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A Prediction Model on the Male Nurses' Turnover Intention (남자 간호사의 이직의도 예측모형)

  • Kim, Su Ol;Kang, Younhee
    • Korean Journal of Adult Nursing
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    • v.28 no.5
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    • pp.585-594
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    • 2016
  • Purpose: The purpose of this study was to develop and test a predictive model on the male nurses' turnover intention. Methods: This study utilized the model-testing design based on the Price's causal model of turnover. This study collected data from 306 male nurses on a national scale with structured questionnaires measuring job opportunity, kinship responsibility, positive emotion, work autonomy, role conflict, work satisfaction, organizational commitment, and turnover intention. The data were analyzed using SPSS/WIN 22.0 program and AMOS 20.0 program. Results: As the outcomes satisfied the recommended level, the hypothetical model appeared to fit the data. Twenty-seven of the 38 hypotheses selected for the hypothetical model were statistically significant. 54.2% of turnover intention was explained by job opportunity, kinship responsibility, positive emotion, work autonomy, role conflict, work satisfaction and organizational commitment. Conclusion: The hypothetical model of this study was confirmed to be adequate in explaining and predicting male nurses' turnover intention. Findings from this study can be used to design appropriate strategies to decrease the male nurse's turnover intention.