• Development and Reproduction
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• v.22 no.2
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• pp.119-132
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• 2018

GnRH (gonadotropin-releasing hormone) is a supreme hormone regulating reproductive activity in most animals. The sequences of amino acid and nucleic acid of GnRH reported up to now are examined from the evolutionary framework of Chordata. All identified GnRH are classified into GnRH1, GnRH2, or GnRH3. In all three forms of GnRH both N-terminal and C-terminal are conserved, which allows for effective binding to their receptors. The three amino acids in the middle of GnRH1 sequence have altered diversely from the primitive Chordata, which is indicative of the adaptation process to the ambient environment. GnRH2 and GnRH3 sequences are well conserved. There are more diverse modifications in the nucleic acids than in amino acid sequence of GnRH1. These variations can result from meiosis, mutation, or epigenetics and indicate that GnRH is the product of natural selection.

• Molecules and Cells
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• v.39 no.10
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• pp.715-721
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• 2016

Plants have become physiologically adapted to a seasonally shifting environment by evolving many sensory mechanisms. Seasonal flowering is a good example of adaptation to local environmental demands and is crucial for maximizing reproductive fitness. Photoperiod and temperature are major environmental stimuli that control flowering through expression of a floral inducer, FLOWERING LOCUS T (FT) protein. Recent discoveries made using the model plant Arabidopsis thaliana have shown that the functions of photoreceptors are essential for the timing of FT gene induction, via modulation of the transcriptional activator CONSTANS (CO) at transcriptional and post-translational levels in response to seasonal variations. The activation of FT transcription by the fine-tuned CO protein enables plants to switch from vegetative growth to flowering under inductive environmental conditions. The present review briefly summarizes our current understanding of the molecular mechanisms by which the information of environmental stimuli is sensed and transduced to trigger FT induction in leaves.

• Journal of the Korea Safety Management & Science
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• v.11 no.3
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• pp.11-18
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• 2009

Unless certain limitation is increasing the number of the job type will be inevitable in the future because of development of industry, adaptation on speedy life style, and leisure oriented nuclear family style. In this paper, a prospective model of supply and demand of work force has been developed basing on various categories of industries and patterns about employees to look over efficient supply and demand of work force suiting employment of work force policies. In this paper, after Analyzing job preference, we have noticed a more stable job system and the results showed significant improvements over the existing job system.

• Journal of Species Research
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• v.10 no.2
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• pp.142-153
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• 2021

Algal genomics approaches provide a massive number of genome/transcriptome sequences and reveal the evolutionary history vis-à-vis primary and serial endosymbiosis events that contributed to the biodiversity of photosynthetic eukaryotes in the eukaryote tree of life. In particular, phylogenomic methods using several hundred or thousands of genes have provided new insights into algal taxonomy and systematics. Using this method, many novel insights into algal species diversity and systematics occurred, leading to taxonomic revisions. In addition, horizontal gene transfers (HGTs) of functional genes have been identified in algal genomes that played essential roles in environmental adaptation and genomic diversification. Finally, algal genomics data can be used to address the pangenome, including core genes shared among all isolates and partially shared strain-specific genes. However, some aspects of the pangenome concept (genome variability of intraspecies level) conflict with population genomics concepts, and the issue is closely related to defining species boundaries using genome variability. This review suggests a desirable future direction to merge algal pangenomics and population genomics beyond traditional molecular phylogeny and taxonomy.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• v.5 no.1
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• pp.28-36
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• 2024

Effect of climate change on the agricultural sector has been predicted and studied, including its effects on coffee cultivation. Climate change can directly impact coffee production or indirectly influence it through its effects on coffee pests. In Indonesia, coffee is a critical export commodity. Climate change can have a large effect on many farmers if it is not addressed appropriately. This study summarizes several studies and data on how climate change affects coffee production and the coffee berry borer (CBB; Hypothenemus hampei) pest in Indonesia. Adaptation plans that can be employed to mitigate impacts of climate change are also summarized.

• Proceedings of the Microbiological Society of Korea Conference
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• 2005.05a
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• pp.64-66
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• 2005

Photosynthetic microbes possess a wealth of photoactive proteins including chlorophyll-based pigments, phototropin-related blue light receptors, phytochromes, and cryptochromes. Surprisingly, recent genome sequencing projects discovered additional photoactive proteins, retinal-based rhodopsins, in cyanobacterial and algal genera. Most of these newly found rhodopsin genes and retinal synthase have not been expressed and their functions are unknown. Analysis of the Anabaena and Chlamyrhodopsin with retinal synthase revealed that they have sensory functions, which, based on our work with haloarchaeal rhodopsins, may use a variety of signaling mechanisms. Anabaena rhodopsin is believed to be sensory, shown to interact with a soluble transducer and the putative function is either chromatic adaptation or circadian rhythm. Chlamydomonas rhodopsins are involved in phototaxis and photophobic responses based on electrical measurements by RNAi experiment. In order to analyze the protein, we developed a sensory rhodopsin expression system in E. coli. The opsin in E. coil bound endogenous all-trans retinal to form a pigment and can be observed on the plate. Using this system we could identify retinal synthase in Anabaena PCC 7120. We conclude that Anabaena D475 dioxygenase functions as a retinal synthase to the Anabaena rhodopsin in the cell.

• Microbiology and Biotechnology Letters
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• v.48 no.4
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• pp.423-428
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• 2020

In vitro evolution is a powerful technique for the engineering of yeast strains to study cellular mechanisms associated with evolutionary adaptation; strains with desirable traits for industrial processes can also be generated. There are two distinct approaches to generate evolved strains in vitro: the sequential transfer of cells in the stationary phase into fresh medium or the continuous growth of cells in a chemostat bioreactor via the constant supply of fresh medium. In culture, evolutionary forces drive diverse adaptive mechanisms within the cell to overcome environmental or intracellular stressors. Especially, this engineering strategy has expanded to the field of human cell lines; the understanding of such adaptive mechanisms provides promising targets for the treatment of human genetic diseases and cancer. Therefore, this technology has the potential to generate numerous industrial, medical, and academic applications.

• Genomics & Informatics
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• v.21 no.2
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• pp.25.1-25.12
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• 2023

Adaptation of infections and hosts has resulted in several metabolic mechanisms adopted by intracellular pathogens to combat the defense responses and the lack of fuel during infection. Human tuberculosis caused by Mycobacterium tuberculosis (MTB) is the world's first cause of mortality tied to a single disease. This study aims to characterize and anticipate potential antigen characteristics for promising vaccine candidates for the hypothetical protein of MTB through computational strategies. The protein is associated with the catalyzation of dithiol oxidation and/or disulfide reduction because of the protein's anticipated disulfide oxidoreductase properties. This investigation analyzed the protein's physicochemical characteristics, protein-protein interactions, subcellular locations, anticipated active sites, secondary and tertiary structures, allergenicity, antigenicity, and toxicity properties. The protein has significant active amino acid residues with no allergenicity, elevated antigenicity, and no toxicity.

• Child Health Nursing Research
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• v.24 no.4
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• pp.454-464
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• 2018

Purpose: The purpose of this study was to develop an experience-based sex education program to improve adjustment to puberty in elementary school students in the upper grades and to verify its effectiveness. Methods: This study had a pretest-posttest nonequivalent control group design. The subjects of this study were a total of 95 sixth-graders in Y city (experimental group: 48, control group: 47). The measurement variables were sexual knowledge, body image, self-esteem, and satisfaction with life. Four sessions of the experience-based sex education program to improve adjustment to puberty, consisting of 40 minutes per session, were provided to the experimental group. Results: Children's sexual knowledge, self-esteem, and satisfaction with life in the experimental group, which participated in the experience-based sexual education program to improve adjustment to puberty, showed a significant increase compared to the control group. However, there was no statistically significant difference in body image. Conclusion: This study presents the development of an experience-based sex education program for adjustment to puberty to overcome the shortcomings of existing sex education programs that are limited to sexual knowledge and attitudes, and also verified that the sexual knowledge, self-esteem, and life satisfaction of the elementary school students who were provided with the program improved meaningfully.

• The Journal of the Korea Contents Association
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• v.21 no.8
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• pp.213-220
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• 2021

The purpose of this study is to pave the way to promote the institutional commitment of the students enrolled by identifying the factors that affects on their institutional commitment. The data collection was conducted starting from November 19, 2020 until November 26, 2020 by using online questionnaires and 220 participants were from C-university students in Chang-won, Kyung-nam Province. As a result of analysis, the average score for institutional commitment was 3.30, the average level of satisfaction of university life was 3.62, the cultural climate was 3.39 and the level of satisfaction for extracurricular program was 3.48, which was in high range. Institutional commitment has a positive correlation between the level of satisfaction of university life, the level of satisfaction for extracurricular programs(p<.001). The most critical factor that affects the institutional commitment was the level of satisfaction of university life and the level of satisfaction for extracurricular programs, the cultural climate in order. The result can be interpreted that institutional commitment is influenced by students' major and the level of satisfaction of university life and the level of satisfaction for extracurricular programs, and the level of satisfaction of university life has relatively high level of influence out of other factors, indicating that the effort to improve the institutional commitment of the students is needed at the collegiate level.