• Title/Summary/Keyword: Activity Test

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Reliability and validity of free software for the analysis of locomotor activity in mice

  • Hong, Yoo Rha;Moon, Eunsoo
    • Journal of Yeungnam Medical Science
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    • v.35 no.1
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    • pp.63-69
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    • 2018
  • Background: Kinovea software that tracking semi-automatically the motion in video screen has been used to study motion-related tasks in several studies. However, the validation of this software in open field test to assess locomotor activity have not been studied yet. Therefore, this study aimed to examine the reliability and validity of this software in analyzing locomotor activities. Methods: Thirty male Institute Cancer Research mice were subjected in this study. The results examined by this software and the classical method were compared. Test-retest reliability and inter-rater reliability were analyzed with Pearson's correlation coefficient and intraclass correlation coefficient (ICC). The validity of this software was analyzed with Pearson's correlation coefficient. Results: This software showed good test-retest reliability (ICC=0.997, 95% confidence interval [CI]=0.975-0.994, p<0.001). This software also showed good inter-rater reliability (ICC=0.987, 95% CI=0.973-0.994, p<0.001). Furthermore, in three analyses for the validity of this software, there were significant correlations between two methods (Pearson's correlation coefficient=0.928-0.972, p<0.001). In addition, this software showed good reliability and validity in the analysis locomotor activity according to time interval. Conclusion: This study showed that this software in analyzing drug-induced locomotor activity has good reliability and validity. This software can be effectively used in animal study using the analysis of locomotor activity.

The Effects of PNF on Active Lumbar Flexion ROM and Activity of Daily Living for Adult Scoliosis with Low Back Pain (급성 요통을 동반한 성인 측만증 환자에게 적용한 고유수용성신경근촉진법이 요부 능동 굴곡 관절가동 범위 및 일상생활동작에 미치는 영향 : 증례보고)

  • Na, Eun-Jin;Shin, Seung-Sub
    • PNF and Movement
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    • v.10 no.4
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    • pp.33-40
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    • 2012
  • Purpose : The purpose of this study was to investigate the effects of PNF on active lumbar flexion ROM and difficulty of activity of daily living for adult scoliosis with low back pain. Methods : A 23-aged adult scoliosis with diagnosed herniated lumbar disc. The patient was treated by PNF for 30 minutes a day, 2 times a week during six weeks. Active lumbar flexion ROM and difficulty of activity of daily living were evaluated by the Modified-Modified Schober test and Oswestry Disability Questionnaire every week after treatment including the pretest of the first day of treatment. Results : There were a significant improvement in active lumbar flexion ROM between pretest and the last test. There were significant decreased in difficulty of activity of daily living positive between pretest and the last test. Conclusion : PNF will be useful for increasing active lumbar flexion ROM and decreasing the difficulty of activity of daily living positive for adult scoliosis with low back pain.

Evaluation of Domestic CCPs(Coal Combustion Products) Quality by API Test Method (API시험법에 의한 국내 석탄회의 품질 평가)

  • Yoo, Sung-Won;Yu, Kyung-Geun;Cho, Young-Keun
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.1 no.1
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    • pp.49-57
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    • 2013
  • Recently, recycling of industrial by-products and CO2 reduction have been important issues in the world. In this reason, applications and reuse of Fly ash as a binder for concrete, which is generated in thermoelectric power plant, have been one of the effective recycle methods. In order for Fly ash to be applied to concrete, Korean Standard(KS) has selected and managed quality such as $SiO_2$, fineness, specific gravity, ignition loss and activity index. However, there is a limits for activity index, whose test period required is at least 28 days or 91 days. Activity index is the critical indication standard to determine mechanical strength of concrete that contained Fly ash. To complement the disadvantage of test method, this research provided "API test method", which quickly measure Pozzolanic reaction of Fly ash can be considered as a alternative of activity index. Then, the adaptable API test method need to be investigated through comparative analysis with the test result of API, activity index and K-value. The test method can make evaluation of Fly ash quality faster and more accurate. As a result, most Fly ash produced in Korea has not been satisfied in the KS quality standard except water content and specific gravity, and especially fluidized bed boiler ash has its characteristics. Also, API, activity index and K-value have superior interrelationship. The interrelationship between API and activity index and K-value gets increased as the material age gets higher, so API test can be considered as very useful test method for Pozzolanic reaction evaluation of Fly ash.

Brassinosteroid-like Activity of Monoglyceride Analogues (Monoglyceride 관련물질의 Brassinosteroid-like 생물활성)

  • Park, Jong-Dae;Park, Keun-Hyung
    • Applied Biological Chemistry
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    • v.40 no.4
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    • pp.357-360
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    • 1997
  • The biological activity of monoglycerides, diglycerides, triglycerides and free fatty acids were investigated by the rice inclination test that is specific bioassay for brassinosteroids. The experimental results revealed that some diglycerides, triglycerides and free fatty acids as well as monoglycerides showed positive response. ${\alpha}-Monoolein$ and diolein as active principles showed higher activity than indole-3-acetic acid at the same concentration. From the results, it can be confirmed that the active principles are related to olein which especially have a high activity.

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Effects of Compost Tea Making from Differently Treated Compost on Plant Disease Control

  • Tateda, Masafumi;Yoneda, Daisuke;Sato, Yukio
    • Journal of Wetlands Research
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    • v.9 no.1
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    • pp.91-98
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    • 2007
  • Antifungal activity of compost teas was evaluated in vitro and in vivo experiments. In vitro test, fourteen compost teas were produced using five different composts and through six different methods for compost tea production. Eleven pathogenic fungi were used as indicators of antifungal activity of compost teas. In vivo test, one of the compost teas used in vitro test was sprayed to cucumber leaves which were infected with powdery mildew in order to evaluate antifungal activity of compost tea. From the results of the tests, it was found that all compost teas used this study showed antifungal activity and the proper application of compost teas against pathogenic fungi for obtaining optimal effects was important to know.

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Antioxidant compounds from the stem bark of Sorbus commixta

  • Na, Min-Kyun;An, Ren-Bo;Lee, Sang-Myung;Min, Byung-Sun;Kim, Young-Ho;Bae, Ki-Hwan;Kang, Sam-Sik
    • Natural Product Sciences
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    • v.8 no.1
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    • pp.26-29
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    • 2002
  • The MeOH extract of Sorbus commixta (Rosaceae) exhibited strong DPPH radical scavenging activity, and through activity-guided fractionation two antioxidant compounds were isolated and identified as $catechin-7-O-{\beta}-D-xylopyranoside$ (1) and $catechin-7-O-\;{\beta}-D-apiofuranoside$ (2) by physicochemical and spectrometric methods. To evaluate the antioxidant effect of these compounds, some in vitro tests, such as the DPPH radical scavenging activity test, the superoxide radical scavenging activity test and the lipid peroxidation inhibitory activity test, were performed. Compounds 1 and 2 showed stronger activities than both a-tocopherol and butylated hydroxy anisole (BHA) in each assay.

Antimicrobial Activity and Safety Test of Natural extract including Phellodendro namurense, Eucommia ulmides Oliv extracts (황벽나무, 두충나무 추출물 등을 포함한 천연 추출물의 항균력 및 안전성)

  • Noh, Daeyoung;Joe, Suehyeon;Yang, Hyunguk;Han, Donggyun;Kim, Jinhong;Kim, Donguk
    • Korean Chemical Engineering Research
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    • v.54 no.6
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    • pp.762-766
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    • 2016
  • In this study, natural extract including Phellodendro namurense, Eucommia ulmides Oliv and Prunus padus were tested for antimicrobial activity and safety. Antimicrobial activity was measured by using opportunistic microbes such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans. As safety test, cell viability test, single dose oral toxicity test, single dose inhalation toxicity test, repeat dose inhalation toxicity test and eye irritation test were done. From antimicrobial test, natural extract showed execellent antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli. From 5 kinds of safety tests, toxicity was not observed. From experimental results, natural extract including Phellodendro namurense, Eucommia ulmides Oliv and Prunus padus showed superb safety and antimicrobial effect.

Effect of the Non-Elastic Taping Method of Controlling Internal Hip Joint Rotation on Hip Muscle Activity: A Preliminary Study (엉덩관절 안쪽돌림 조절을 위한 비탄력 테이핑 방법이 엉덩관절 근활성도에 미치는 영향 -예비연구-)

  • Song-Ui Bae;Ju-Hyeon Jung;Dong-Chul Moon
    • PNF and Movement
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    • v.21 no.3
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    • pp.281-289
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    • 2023
  • Purpose: This study investigated the effects of the non-elastic taping method for controlling internal hip joint rotation on internal and external hip rotator muscle activity in healthy people. Methods: In this study, 18 healthy volunteers were instructed to perform the small knee bending (SKB) test. All participants completed the test following two methods (using non-elastic taping and not using taping). Muscle activation during the two methods was measured using a surface electromyography (EMG) device. Surface EMG data were collected from the gluteus medius, gluteus maximus, and tensor fasciae femoris muscles while performing the SKB test with and without non-elastic taping. Results: Muscle activity in the gluteus maximus was significantly higher during the SKB test with non-elastic taping than during the conventional SKB test with taping (p < 0.05). Tensor fasciae latae muscle activity was lower during the SKB test with non-elastic taping than during the conventional SKB test (p < 0.05). Conclusion: The findings suggest that the non-elastic taping method for controlling internal hip joint rotation effectively activates the hip's external rotator muscles and minimizes unwanted internal rotator muscle use during the SKB test. Therefore, the non-elastic taping method for controlling internal hip joint rotation could be an effective intervention for those who cannot control the internal rotation of their hips.

Usage of Enzyme Substrate to Protect the Activities of Cellulase, Protease and α-Amylase in Simulations of Monogastric Animal and Avian Sequential Total Tract Digestion

  • Wang, H.T.;Hsu, J.T.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.8
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    • pp.1164-1173
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    • 2006
  • Cellulase from Aspergillus niger, (${\alpha}$-amylase from Bacillus sp. and protease from Bacillus globigii were used as enzyme sources in this study to examine how their respective substrates protect them in two kinds of simulated gastrointestinal tract digesting processes. Avian total digest tract simulation test showed that filter paper, Avicel and cellulose resulted in 7.7, 6.4 and 7.4 times more activity than of unprotected cellulose, respectively. Protease with addition of casein, gelatin or soybean protein showed no significant protection response. Starch protected amylase to be 2.5 times activity of the unprotected one. Monogastric animal total tract digestion simulation test showed that filter paper, Avicel and cellulose resulted in 5.9, 9.0 and 8.8 times activity of unprotected cellulase, respectively. Casein, gelatin and soybean protein resulted in 1.2, 1.3 and 2.0 times activity of unprotected protease, respectively. Starch did not protect amylase activity in monogastric animal total tract simulation. Protection of mixed enzymes by substrates in two animal total tract simulation tests showed that filter paper in combination with soybean protein resulted in 1.5 times activity of unprotected cellulose, but all substrates tested showed no significant protection effect to protease. Soybean protein and starch added at the same time protected the amylase activity to be two times of the unprotected one. Test of non-purified substrate protection in two animal total digest tract simulation showed that cellulase activity increased as BSA (bovine serum albumin) concentration increased, with the highest activity to be 1.3 times of unprotected enzyme. However, BSA showed no significant protection effect to protease. Amylase activity increased to 1.5 times as BSA added more than 1.5% (w/v). Cellulase activity increased to 1.5 times as soybean hull was added higher than 1.5%. Amylase had a significant protection response only when soybean hull added up to 2%. Protease activity was not protected by soybean hull to any significant extent.

A Study on Depression and Activity of Daily Living in Patients with Rheumatoid Arthritis by Gender (성별에 따른 류마티스 관절염 환자의 우울과 일상활동정도)

  • Yoo, Kyung Hee
    • Journal of muscle and joint health
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    • v.20 no.2
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    • pp.131-140
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    • 2013
  • Purpose: The purpose of this study was to investigate depression and activity of daily living of patients with rheumatoid arthritis by their gender. Methods: The subjects for this study were 184 patients registered in S University Hospital. and the period of data collection was from May 1, 2012 to August 20, 2012. The data were analyzed with t-test, ANOVA, Mann-Whitney U test, Kruskal-Wallis H test, and Pearson's correlation. Results: For depression, there were significant differences by marriage and religion in male patients and by education in female patients. For activity of daily living, there were significant differences by marriage, age and education in female patients. Depression was negatively correlated with activity of daily living in patients with rheumatoid arthritis. Conclusion: Managing depression and activity of daily living were important for both male and female patients with rheumatoid arthritis. To promote the quality of life of patients with rheumatoid arthritis, nursing intervention strategies must be developed for decreasing depression or improving their activity of daily living.