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http://dx.doi.org/10.9713/kcer.2016.54.6.762

Antimicrobial Activity and Safety Test of Natural extract including Phellodendro namurense, Eucommia ulmides Oliv extracts  

Noh, Daeyoung (Department of Pharmaceutical Engineering, Inje University)
Joe, Suehyeon (Department of Pharmaceutical Engineering, Inje University)
Yang, Hyunguk (Department of Pharmaceutical Engineering, Inje University)
Han, Donggyun (Department of Pharmaceutical Engineering, Inje University)
Kim, Jinhong (Biometics)
Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
Publication Information
Korean Chemical Engineering Research / v.54, no.6, 2016 , pp. 762-766 More about this Journal
Abstract
In this study, natural extract including Phellodendro namurense, Eucommia ulmides Oliv and Prunus padus were tested for antimicrobial activity and safety. Antimicrobial activity was measured by using opportunistic microbes such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans. As safety test, cell viability test, single dose oral toxicity test, single dose inhalation toxicity test, repeat dose inhalation toxicity test and eye irritation test were done. From antimicrobial test, natural extract showed execellent antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli. From 5 kinds of safety tests, toxicity was not observed. From experimental results, natural extract including Phellodendro namurense, Eucommia ulmides Oliv and Prunus padus showed superb safety and antimicrobial effect.
Keywords
Phellodendro namurense; Eucommia ulmides Oliv; Antimicrobial activity; Safety; Natural extract;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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