• Convergence Security Journal
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• v.14 no.3_2
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• pp.93-98
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• 2014

In a recent survey conducted among Seoul citizens, the demand for crime prevention in addition to settlement of environmental problem and traffic system improvement turned out to be the highest. In particular, the demand for prevention of crimes in residential areas was higher than any other items. The crime rates are especially high in deteriorated residential districts, which indicates the relation between crimes and physical environmental factors. In other words, proper measures for surroundings can prevent crimes. While there may be various ways to keep the residents from crimes safely, CPTED, a crime preventive method in a way of improving the physical surroundings is one of the most noteworthy solutions. The principles of CPTED involves the basic principles such as Natural Surveillance, access control, and securing of territoriality and additional principles of strengthening of Activity Support and Maintenance & Management. This study aims to present a method to lower and prevent crime occurrences by applying the principles of CPTED in deteriorated Apartment Housing in the middle of a city.

• Korean Journal of Occupational Health Nursing
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• v.10 no.2
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• pp.153-163
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• 2001

Purpose of the study was to identify the relationship between job stress and health promoting behavior(HPB) among nurses. Samples were 426 nurses working in some university hospitals which were chosen by convenient sampling. Data was collected by using constructed questionnaires from March 28th to April 7th 2001. The instruments used for in the study were 'The Health Promotion Behavior' which was developed by Park(1995) and 'The Job Stress' modified by Kim(1998). The data was analyzed by mean, standard deviation, t-test, ANOVA, Duncan test and Pearson's correlation coefficient in the SPSS program. The results were as follows : 1. The mean score of job stress was 3.51 which is meant to be 'more than moderate' level of stress. 2. The total mean score of health promoting behavior was 2.44; 'Management of Sanitary life' 3.12, 'Harmonious relation-ships' 2.95, 'Emotional support' 2.71, 'Diet control' 2.59, 'Self-achievement' 2.57, 'Self-control' 2.31, 'Healthy diet' 2.29, 'Rest and sleep' 2.26, 'Exercise and activity' 2.12, 'Regular diet' 1.91 and 'Professional health maintenance' 1.61 were shown in each HPB category. 3. There were not any statistical differences between job stress and general characteristics of nurses. 4. The health promoting behavior was significantly influenced by factors of age, marital status, education level, religion, position, career and family income of nurses. 5. There was not any correlations between job stress and health promoting behavior.

• Human Ecology Research
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• v.58 no.1
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• pp.105-120
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• 2020

This study helps infant teachers practice a constructivism-based teacher education program that supports infant mathematical inquiry activities and examines improvements in mathematical teaching knowledge, mathematical teaching initiatives, mathematical interaction, constructivism belief and mathematical teaching efficacy. Twenty two experiment group infant teachers and twenty two comparison group infant teachers were chosen at two workforce educare centers. The experiment group infant teachers participated in 18 sessions of a constructivism teacher training program for 8 weeks, but the comparison group infant teachers did not take part in the program. Pretest and post-tests were implemented for the mathematical teaching knowledge, mathematical teaching initiatives, mathematical interactions, constructivism belief and mathematical teaching efficacy in the experiment group. Independent sample t-test and ANCOVA were tested using Windows SPSS statistics 21.0. The homogeneity test for the experiment and comparison group revealed significant differences. ANCOVA was carried out after the pretest score was controlled as a co-variance. Significant differences were indicated in mathematical teaching knowledge, mathematical teaching initiative, mathematical interaction, constructivism belief and mathematical teaching efficacy. The results indicated that a constructivism-based teacher education program to support infant mathematical inquiry activities influenced improvements in mathematical teaching knowledge, mathematical teaching initiative, mathematical interaction, constructivism belief and mathematical teaching efficacy. This study proved the effects of the program based on constructivism theory content for the knowledge, skills and attitude about infant teaching of mathematical initiatives and practiced a program of exploration, investigation, application and assessment for infant teachers. The results can help infant teachers teach mathematical exploration activities and help activate infant mathematical exploration activities.

• Architectural research
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• v.15 no.2
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• pp.77-86
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• 2013

Cohousing is based on collaborative network, or fictive kin in the community. It could facilitate the goal of self-sufficiency. This research aims to investigate the motivation of move to cohousing communities in Sweden, and to find out if there are any significant differences according to two different cohousing types; between the +40 cohousing and the mixed-age cohousing. The +40 cohousing is a kind of senior cohousing in which residents are supposed to be aged over 40. Questionnaire survey was applied and 242 collected data were analyzed by SPSS statistical program. Notable differences in demographic and dwelling variables are found between the 2 groups. There are more women, singles, academics, and small dwellings in the +40 cohousing than in the mixed-age cohousing. Referring motivation of move, "sharing common activity" and "idea of cohousing" are commonly noticed as the main reasons why people move to cohousing communities. Major difference between the 2 groups is that residents of the +40 cohousing tend to stress more on social interaction with neighbors than practical merit. On the contrary, ones of the mixed-age cohousing focus more on practical advantage than social interaction. As a conclusion, it is evident that motivation of move to cohousing communities is different by cohousing types, which have different residents' characteristics. Cohousing could contribute to elevate marginal group's quality of life as an alternative living environment. Therefore, cohousing design has to be tailored to adapt residents' specific needs of different life-stages. In order to implement cohousing model into other countries, for instance into Korea, it needs to experiment with the notion of transplanting selected cohousing principles to a public housing development. In the mixed-age cohousing where more dual income families with young children than conventional housing developments reside, residents would need more practical advantage than emotional support in the community, while as residents in the senior cohousing need vice versa.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8617-8622
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• 2014

The goal of this study was to establish paclitaxel resistant MCF-7 cells, as in vitro model, to identify the molecular mechanisms leading to acquired chemoresistance in breast cancer cells. Resistant cells were developed by stepwise increasing exposure to paclitaxel. Gene expression levels of Bax and Bcl-2 along with protein levels of caspase-8 and caspase-9 were evaluated in two resistant cell lines (MCF-7/Pac64 and MCF-7/Pac5 nM). Morphological modifications in paclitaxel resistance cells were examined by light microscopy and fluorescence activated cell sorting (FACS). As an important indicator of resistance to chemotheraputic agents, the Bcl-2/Bax ratio showed a significant increase in both MCF-7/Pac5nM and MCF-7/Pac 64nM cells (p<0.001), while caspase-9 levels were decreased (p<0.001) and caspase-8 was increased (p<0.001). FACS analysis demonstrated that MCF-7/Pac64 cells were smaller than MCF-7 cells with no difference in their granularity. Our results support the idea that paclitaxel induces apoptosis in a mitochondrial-dependent manner. Identifying breast cancer patients with a higher Bcl-2/Bax ratio and caspase 9 level and then inhibiting the activity of these proteins may improve the efficacy of chemotheraputic agents.

• Biomedical Science Letters
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• v.11 no.3
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• pp.327-332
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• 2005

Sf21 cells become popular as the host permissive cell line to support the baculovirus AcNPV replication and protein synthesis. The cells grow well on TC-100 medium that contains $0.1\%$ D-glucose as the major carbon source, strongly suggesting the presence of endogenous glucose transporters. However, unlike human glucose transporters, very little is known about the characteristics of the endogenoussugar transporter(s) in Sf21 cells. Thus, some kinetic properties of the sugar transport system were investigated, involving the uptake of 2-deoxy-D-glucose (2dG1c). In order to obtain a true measure of the initial rate of uptake, the uptake of $[^3H]2dGlc$ from both low $(100{\mu}M)$ and high (10 mM) extracellular concentrations was measured over periods ranging from 30 sec to30 min. The data obtained indicated that the uptake was linear for at least 2 min at both concentrations, suggesting that measurements made over a 1min time course would reflect initial rates of the jexpse uptake. To determine $K_m\;and\;V_{max}$ of the endogenous glucose transporter(s) in Sf21 cells, the uptake of 2dG1c was measured over a range of substrate concentrations $(50{\mu}M\~10mM)$ 2dG1c uptake by the Sf21 cells appeared to involve both saturable and non-saturable (or very low affinity) components. A saturable transport system for 2dG1c was relatively high, the $K_m$ value for uptake being < 0.45 mM. The $V_{max}$ value obtained for 2dG1c transport in the Sf21 cells was about 9.7-folds higher than that reported for Chinese hamster ovary cells, which contain a GLUT1 homologue. Thus, it appeared that the transport activity of the Sf21 cells was very high. In addition, the Sf21 glucose transporter was found to have very low affinity for cytochalasin B, a potent inhibitor of human erythrocyte glucose transporter

• BMB Reports
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• v.37 no.5
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• pp.618-624
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• 2004

All members of R. glutinosa show the unique characteristic of intrinsic tolerance to paraquat (PQ). Antioxidant enzymes have been proposed to be the primary mechanism of PQ resistance in several plant species. Therefore, the antioxidant enzyme systems of R. glutinosa were evaluated by comparatively analyzing cellular antioxidant enzyme levels, and their responses of oxidative stresses and hormones. The levels of ascorbate peroxidase (APX), glutathione reductase (GR), non-specific peroxidase (POX), and superoxide dismutase (SOD) were 7.3-, 4.9-, 2.7- and 1.6-fold higher in PQ-tolerant R. glutinosa than in PQ-susceptible soybeans. However, the activity of catalase (CAT) was about 12-fold higher in the soybeans. The activities of antioxidant enzymes reduced after PQ treatment in the two species, with the exception of POX and SOD in R. glutinosa, which increased by about 40%. Interestingly, the activities of APX, SOD and POX in R. glutinosa, relative to those in soybeans, were further increased by 49, 67 and 93% after PQ treatment. The considerably higher intrinsic levels, and increases in the relative activities of antioxidant enzymes in R. glutinosa under oxidative stress support the possible role of these enzymes in the PQ tolerance of R. glutinosa. However, the relatively lower levels of SOD versus PQ tolerance, and the mixed responses of antioxidant enzymes to stresses and hormones, suggest a possible alternative mechanism(s) for PQ tolerance in R. glutinosa.

• Journal of the Korean Society of Costume
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• v.66 no.7
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• pp.192-208
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• 2016

Due to the paradigm shift in fashion industry, its contribution to social activities and social enterprises' practice of ethical fashion has been on the rise lately. The surveillance and regulations of international community have increased in light of the betterment of working conditions and protection of the rights, and corporate social responsibility has been emphasized through consumers' interest in ethical consumption. In this regard, the fashion social enterprises' responsible and ethical management can both boost the trust in business and value-added. The study aims to propose feasible methods by exploring ways to induce support from central and local governments, which will lead to the activation of future fashion social enterprises and paradigms shift of consumers's perception and value. The sustainability of social enterprises requires management line or policies that consider social, environmental, economic, and political aspects of virtuous cycle, differentiated internally or externally. Fashion social enterprises also need ethic management and social responsibility management that are distinctive from general fashion enterprises. Thus, they will not be sustainable or differentiated unless entrepreneurial faith and role is not clear. Education and continuous promotion including upcycling are critical to build consumer base as they can make consumers spend ethically and recognize social enterprises. In addition, social education and public relations need to take place in order to internalize consumer pattern. The goal of sustainable corporate social activity is to change the awareness and become social investment that returns some profits to the society as members in line with reviewing corporate image. This can lead to establishing the foundation of securing a big comsumer market and winning the trust of the consumer's through corporate social responsibility and investment.

• The Korean Journal of Community Living Science
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• v.26 no.3
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• pp.457-469
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• 2015

This study examines the effects of health-promoting behaviors of grandmothers participating in their infant grandchildren's nurture and provides data for enhancing the quality of their lives. The sample included 218 consenting subjects who understood the purpose of the study. These subjects resided in three cities in Jeollanam-do, Korea, and were grandmothers entrusted by their adult children with a considerable amount of nurturing for their preschool-aged grandchildren under the age of six. First, the subjects scored an average of 3.05 for health-promoting behaviors and 2.42 for entrapment. Second, the entrapment measurement based on general characteristics showed a higher level of entrapment for those with better health, a lower education level, no religion, male grandchildren to nurture, and unsatisfactory compensation. Third, health-promoting behaviors and entrapment (r=-.304) were negatively correlated. Fourth, the analysis results for effects of health-promoting behaviors of grandmothers on entrapment based on general characteristics of grandmothers as a control variable reveal a significant effect of health-promoting behaviors on entrapment. In other words, the greater the employment of health-promoting behaviors, the less likely the entrapment was to be perceived. Fifth, the results for effects of subcriteria for health-promoting behaviors on entrapment reveal a decrease in entrapment when the subjects engaged in an appropriate level of physical activity with a relaxed state of mind. These results suggest that health-promoting behaviors of grandmothers participating in their infant grandchildren's nurture are likely to influence entrapment and thus that grandmothers should make efforts to actively engage in health-promoting behaviors to reduce any maladaptive effects on nurturing. Social support and related programs should be fostered to enable grandmothers to better practice health-promoting behaviors while nurturing their grandchildren.

• CELLMED
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• v.2 no.1
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• pp.9.1-9.13
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• 2012

Jeechool-Whan (JW) is a prescription of Ponciri Fructus Immaturus and Atractylodis Rhizoma Alba and improves the functions of the stomach and the spleen. Although it is said in Korean Medicine that the spleen and the stomach are the roots of the body's resistance, the meaning of 'improving the spleen and the stomach' is very comprehensive. Moreover, there are lots of drugs that are said to improve the spleen and the stomach, and the number of prescriptions using these drugs is huge. In this study, we focused on the new effect and mechanism of the JW on the ovalbumin (OVA)-induced allergic rhinitis (AR) model. The increased number of rubs and the increased levels of IgE and histamine in the OVA-sensitized mice were inhibited by JW administration. The balance of Th1/Th2 cytokine level was regulated by JW administration. The levels inflammatory proteins were decreased by JW administration in the nasal mucosa of the OVA-sensitized mice. Eosinophils and mast cells infiltration increased by OVA-sensitization was also decreased in the JW-administered mice. In addition, JW inhibited caspase-1 activity in the same nasal mucosa tissue. In activated human mast cells, JW inhibited the receptor interacting protein-2, I${\kappa}$B kinase-${\beta}$, nuclear factor-${\kappa}$B/Rel A, and caspase-1 activation. In conclusion, this study will be support the clear understanding of the concept of the spleen and the stomach in traditional Korean medicine as well as for a possibility of finding a cure for this AR in traditional medical treatments.