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On the osseointegration of zirconia and titanium implants installed at defect site filled with xenograft material (이종골 이식을 동반한 지르코니아와 타이타늄 임플란트의 골유착에 관한 연구)

  • Kim, Sung-Won;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.52 no.1
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    • pp.9-17
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    • 2014
  • Purpose: The purpose of this study was to compare zirconia implants with titanium implants from the view point of biomechanical stability and histologic response on osseointegration when those were placed with xenograft materials. Materials and methods: Specimens were divided into two groups; the control group was experimented with eighteen titanium implants which had anodized surface and the experimental group was experimented with eighteen sandblasted zirconia (Y-TZP) implants. At the tibias of six pigs, implants were installed into bone defect sites prepared surgically and treated with resorbable membranes and bovine bone. Two pigs were sacrificed after 1, 4 and 12 weeks respectively. Each implant site was sampled and processed for histologic and histomorphometric analysis. The stability of implants was evaluated with a $Periotest^{(R)}$. And the interfaces between bone and the implant were observed with a scanning electron microscope. Results: In stability analysis there was no significant difference between Periotest values of the control group and the experimental group. In histologic analysis with a light microscope after 4 weeks, there was new bone formation with the resorption of bovine bone and the active synthesis of osteoblasts in both groups. In bone-implant contact percentage there was significant difference between both groups (P<.05). In bone area percentage there was no significant difference between both groups. In analysis of both groups with a scanning electron microscope there was a gap between bone and a surface at 4 weeks and it was filled up with bone formed newly at 12 weeks. Conclusion: When accompanied by xenograft using membrane, bone to implant contact percentage of zirconia implants used in this experiment was significantly less than that of the titanium implants by surface treatment of anodic oxidation. So, it is considered that the improvement of zirconia implant is needed through ongoing research on surface treatment methods for its practical use.

THE EFFECT OF ALTERED FUNCTIONAL FORCE ON THE EXPRESSION OF SPECIFIC MRNAS IN THE DEVELOPING MOUSE MANDIBLE (하악골의 발육중인 생쥐에서 기능력의 변화가 특이-유전자 발현에 미치는 영향)

  • Kim, Hyung-Tae;Park, Joo-Cheol;Lee, Chang-Seop;Park, Heon-Dong
    • Journal of the korean academy of Pediatric Dentistry
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    • v.30 no.2
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    • pp.308-319
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    • 2003
  • Mechanical forces are known to have an effect on bone formation, maintenance and remodeling, and there is evidence that the development of the mandibular condyle in the rat or mouse is influenced by altered functional force. However, studies are lacking in molecular-biologic mechanism such as the identification of differentiation factor induced from functional force. Here a mouse model was used to investigate the functional stress-responsive gene or factors which is related to the altered force by comparing the expression genes of functional state and hypo-functional state of the mouse mandible. ICR mice were provisioned with either a soft, mushy diet (soft-diet group) or hard rat pellets (hard-diet group) beginning at weaning for the alteration of functional force and subsequently sacrificed at 89 days of age. Incisor of mice in group 1 were trimmed twice a week to reduce occlusal forces. After killing the animals, mandibular bone including condyle were collected for RNA extraction, subtractive hybridization, northern blot analysis and mRNA in-situ hybridization. The results as follows; 1. A total of 39 clones were sequenced, and 11 individual sequence types were subsequently identified by subtractive hybridization, as 28 clones were represented twice in the analyzed sets. 2. Consequently four candidate clones, FS-s (functional stress-specific)2, -5, -18, and -22 were identified and characterized by homolgy search and northern analysis. Four of these clones, FS-s2, -5, -18, and -22, were shown to be expressed differentially in the hard-diet group. 3. Histologic sections showed that osteoblastic activity along the bone trabeculae and active bone remodeling were significantly lower in soft than in hard diet animals. A soft diet seems to enable a longer period of endochondral ossification in the mandibular condyle. 4. Although the mRNAs of FS-s2, -5, -18, and -22 were expressed rarely by cells of the soft-diet group, highest expression was detected in the cells of the hard-diet group. Together with the above results, it is suggested that FS-s2, -5, -18, and -22 could act as an important factors controlling the tissue changes in response to functional stress. The exact functional significance of these findings remains to be established.

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A comparison between impulse oscillometry system and spirometry for spirometry for detecting airway obstruction in children (소아의 기도 폐쇄 평가에서 impulse oscillometry system과 폐활량 측정법의 비교)

  • Hur, Hae Young;Kwak, Ji Hee;Kim, Hyoung Yun;Jung, Da Wun;Shin, Yoon Ho;Han, Man Yong
    • Clinical and Experimental Pediatrics
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    • v.51 no.8
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    • pp.842-847
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    • 2008
  • Purpose : Measurement of forced expiratory volume in 1 second ($FEV_1$) is usually difficult to obtain in children under six years of age because it requires active cooperation. This study evaluates the sensitivity of impulse oscillometry system (IOS) parameters for detecting airway obstruction in comparison with $FEV_1$. Methods : We studied 174 children who performed the lung function and methacholine challenge tests to diagnose asthma by IOS and spirometry. Children were divided into two subgroups according to their $PC_{20}$, which is a parameter for bronchial sensitivity. We compared IOS parameters with $FEV_1$ at the baseline, post-methacholine challenge, and evaluated their correlation. Results : At the baseline, reactance at 5 Hz (X5) and resistance at 5 Hz (R5) significantly differed between the $PC_{20}$ positive ($PC_{20}{\leq}16mg/mL$) group and $PC_{20}$ negative ($PC_{20}$ >16 mg/mL) group; however, $FEV_1$, $FEV_1$ % predicted, $FEV_1_-Zs$ (Z score) did not differ. $FEV_1$ is correlated with X5 (r=0.45, P<0.01) and R5 (r=-0.69, P<0.01). $FEV_1_-Zs$ is also correlated with X5_Zs (r=-0.26, P<0.01) and R5_Zs (r=-0.31, P<0.01). After the methacholine challenge test, dose-response slopes in $FEV_1$ and X5 significantly differed between the two subgroups (P<0.05). Conclusion : IOS parameters were more discriminative than $FEV_1$ for detecting decreased baseline lung function between two subgroups and have a good correlation with $FEV_1$.

Response to Specific Fertilizer on Chestnut Tree (II) -Deficiency of Insolation and Effect of the Compound Fertilizer with MgO Component- (밤나무 시비시험(施肥試驗)(II) -일조량부족(日照量不足)과 MgO의 시비효과(施肥効果)-)

  • Chung, In Koo;Kang, Sin Woo;Lee, Meong Sun
    • Journal of Korean Society of Forest Science
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    • v.58 no.1
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    • pp.17-22
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    • 1982
  • During the two-years(1979 to 1980) fertilization trial on 4-year-old chestnut tree plantations, total insolation was diminished in 1980 because of unseasonable weather. In every fertilization treatment plot, especially in the NPK-fertilized plot with magnesium, growth of trees and yield of chestnuts have been increased significantly. The results obtained are as follows: 1) The growth in the NPK-fertilized plot with boron and magnesium was 20 percent higher than in plots fertilized with NPK alone. 2) Although there was some frost damage to trees on November 14, 1979, the 1979 weather was otherwise normal and daily insolation averaged 7 hours from June through september, The 1979 fertilization indices for chesnut yield were 167 for NPK with boron and 207 for NPK with magnesium, as compared with the base index of 100 for NPK alone. 3) In 1980, the second year of the fertilization trial, unseasonable weather decreased the average daily insolation from June through September to 3.8 hours. Under such conditions, the fertilization indices for chestnut yield were 620 for NPK with boron and 741 for NPK with magnesium, and Boron, as compared to the base index of 100 for NPK alone; i.e. the yields of plots treated with NPK and magnesium were 21 percent higher than for plots with NPK and boron and 7 times the yields for plots with NPK alone, But in the trial plot of NPK, yield of chestnut in 1980 decreased compared with 1979, 4) All test plots had natural magnesium levels lower than 0.8me/100gr., and the treatments with NPK and magnesium would have been less apparent on soils with higher magnesium level. The spectacular effects of treatment with NPK and magnesium during periods of low insolation may result from increased chlorophyll production and corresponding increases in active carbon assimilation, which should play an important role in carbohydrate formation.

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Ubiquitous Sensor Network Application Strategy of Security Companies (시큐리티업체의 유비쿼터스 센서네트워크(USN) 응용전략)

  • Jang, Ye-Jin;An, Byeong-Su;Ju, Choul-Hyun
    • Korean Security Journal
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    • no.21
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    • pp.75-94
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    • 2009
  • Since mechanical security systems are mostly composed of electronic, information and communication devices, they have effects in the aspects of overall social environment and crime-oriented environment. Also, the importance is increasing for wireless recognition of RFID and tracing function, which will be usefully utilized in controlling the incomings and outgoings of people/vehicles or allowance, surveillance and control. This is resulting from the increase in the care for the elderly according to the overall social environment, namely, the aging society, and the number of women entering, as well as the increase in the number of heinous crimes. The purpose of this study is to examine the theoretical considerations on ubiquitous sensor network and present a direction for securities companies for their development by focusing on the technological and application areas. To present strategies of response to a new environment for security companies, First, a diversification strategy is needed for security companies. The survival of only high level of security companies in accordance with the principle of liberal market competition will bring forth qualitative growth and competitiveness of security market. Second, active promotion by security companies is needed. It is no exaggeration to say that we are living in the modern society in the sea of advertisements and propaganda. The promotional activities that emphasize the areas of activity or importance of security need to be actively carried out using the mass media to change the aware of people regarding security companies, and they need to come up with a plan to simultaneously carry out the promotional activities that emphasize the public aspect of security by well utilizing the recent trend that the activities of security agents are being used as a topic in movies or TV dramas. Third, technically complementary establishment of ubiquitous sensor network and electronic tag is needed. Since they are used in mobile electronic tag services such as U-Home and U-Health Care, they are used throughout our lives by forming electronic tag environment within safe ubiquitous sensor network based on the existing privacy guideline for the support of mobile electronic tag terminal commercialization, reduction in communication and information usage costs, continuous technical development and strengthening of privacy protection, and the system of cooperation of academic-industrial-research needs to be established among the academic world and private research institutes for these parts.

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A Study for Quality of Life in Musically Talented Students Using Experience Sampling Method (경험표집법(ESM)을 통해 본 음악영재의 삶의 질)

  • Lee, Hyun-Joo;Choe, In-Soo
    • Journal of Gifted/Talented Education
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    • v.21 no.1
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    • pp.57-81
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    • 2011
  • The purpose of this study was to explore the quality of life of musically talented students as measured by their external experiences (e.g., activities, companions) and internal experiences (e.g., flow, emotion). The participants in this study were 33 musically talented students (10 males, 23 females) aged 13 to 19. Study data were collected for 7 consecutive days using the Experience Sampling Method (ESM), which employs a cellular-phone as a signaling device. The results were as follows: First, in response to the 1625 random signals, musically talented students reported that 40.9% of their time was spent on productive activities. An additional 33.4% of time was used for maintenance activities and the rest of their time was spent on leisure/social activities. Also, musically talented students reported that 48.5% of their time was spent alone. When they were alone, they spent a lot of time engaging in productive activities (44.3%). Second, in order to measure the flow of their life, two methods were used. One used a 4-channel flow model (i.e. apathy, boredom, flow, anxiety) and the other used 8 dimensions and conditions of the flow experience (i.e. concentration, self-consciousness disappears, action and awareness merge, distorted sense of time, freedom from worry about failure, clear goals, immediate feedback, balance between challenges and skills). According to the former, when engaged in music-related activities, musically talented students usually reported flow (54.0%), while they felt apathy (41.3%) for daily routines activities. According to the latter method, musically talented students experienced flow for most productive activities, while they experienced flow least for maintenance activities. Emotional variables of ESF are comprised of 10 semantic scales (i.e. happy-sad, strong-weak, active-passive, sociablelonely, proud-ashamed, involved-detached, excited-bored, clear-confused, relaxed-worried, cooperative-competitive). Musically talented students reported experiencing the most positive emotion for social activities and experiencing the most negative emotion for maintenance activities. Results of this study assert that musically talented students had to trade off immediate enjoyment for developing their special gifts. They could not afford as much time for socializing with friends, and they had to spend more time alone compared to their peers without such gifts. Consequently, they were found to deprive themselves of the spontaneous good times that teenagers usually thrive on. They were helped in this respect by their autotelic personality traits, especially their strong need for achievement and endurance. The downside, however, is that the moment-to-moment quality of their moods suffered. The argument concerning musically talented students applies for all adolescents. The choices that talented students must make between immediate gratification and long-term development, and between solitude and companionship, are the same choices every young person must make, regardless of her or his level of talent. All of us have gifts that are potentially useful and worthy of being appreciated. But to develop these latent talents we must cultivate them, and this takes time and the investment of mental energy. The lifestyle that musically talented students develop can show us some of the choices all of us must make in order to cultivate our gifts.

Comparison of Non-structural Carbohydrate Concentration Between Zoysiagrass and Creeping Bentgrass During Summer Growing Season (하계 생육기 동안 Zoysiagrass와 Creeping Bentgrass의 비구조적 탄수화물 함량의 비교)

  • Kim, Dae-Hyun;Jung, Woo-Jin;Lee, Bok-Rye;Kim, Kil-Yong;Kim, Tae-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.2
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    • pp.145-152
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    • 2002
  • To compare the Carbon metabolic response to high temperature stress in Zoysiagrass [Zoysia matrella (L.) Merr.] and Creeping bentgrass (Agrostis palustris Huds) with respect to heat tolerance, C metabolites were determined from April to September. Sampling was carried out on an established golf course (Muan Country Club, Chonnam, Korea). Shoot mass(g Dry weight per hole cup) of creeping bentgrass started to decrease from June and recovered from August whereas that of zoysiagrass was less varied. Chlorophyll content in creeping bentgrass was significantly higher than zoysiagrass until July, and then decreased by 43% from July to August. Zoysiagrass contained higher soluble sugar than creeping bentgrass throughout experimental period. Soluble sugar in zoysiagrass increased about 58% from April to May, and less varied until August. Soluble sugar in creeping bentgrass slightly increased until July and sharply decreased at August. Starch concentration in zoysiagrass continuously decreased to September after a significant increase from April to May. A remarkable fluctuation in both starch and fluctuation concentration was observed between June and August showing high accumulation for June to July and high degradation for July to August. These results suggest that through creeping bentgrass suffers much severely from high temperature stress than zoysiagrass especially June to August. An active accumulation and degradation in nonstructural carbohydrate in creeping bentgrass during this period might be associated with heat stress.

Clinical Utility of Bronchial Washing PCR for IS6110 and Amplicor for the Rapid Diagnosis of Active Pulmonary Tuberculosis in Smear Negative Patients (객담도말 음성인 폐결핵환자의 기관지세척액에서 Amplicor PCR과 IS61110 PCR의 임상적 유용성에 관한 비교 연구)

  • Lee, Jun-Gu;Kim, Young-Sam;Park, Jae-Min;Ko, Won-Ki;Yang, Dong-Goo;Kim, Se-Kyu;Chang, Joon;Kim, Sung-Kyu;Choi, Jong-Rak
    • Tuberculosis and Respiratory Diseases
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    • v.50 no.2
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    • pp.213-221
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    • 2001
  • Background : There is a well recognized interlaboratory variation in the results using the polymerase chain reaction(PCR) to detect the IS6110 sequence. The clinical utility of a commercially developed PCR test(Amplicor) in bronchial washings for detecting pulmonary tuberculosis in smear negative patients was evaluated. The sensitivity and specificity of Amplicor was compared with that of an in-house PCR test used for detecting the IS6110 sequence of Mycobacterium tuberculosis(M.tbc) in the bronchial washing fluid. Methods : 66 patients whose sputum smear for M. tbc were negative or who could not produce any sputum were recruited from January 1999 to July 1999. They all had a bronchoscopy performed to determine if there were signs of hemoptysis, patients who could not cough up sputum, lung lesion that exclude pulmonary tuberculosis. Pulmonary tuberculosis was diagnosed on the basis of a positive culture or a response to anti-tuberculosis therapy. Results : 19 patients with tuberculosis were identified and samples from 16 patients were later confirmed by culture. Bronchial washing for Amplicor PCR revealed a sensitivity, specificity, positive and negative predictive values of 94.7%, 97.9%, 94.7%, 97.9%, respectively. Using IS6110 based PCR, the sensitivity, specificity, positive and negative predictive values were of 73.7%, 87.2%, 70%, 89.1% respectively. Conclusion : Bronchial washing for Amplicor PCR proved to be more useful than IS6110 based PCR in rapidly diagnosing smear negative pulmonary pulmoary tuberculosis in patients where tuberculosis was likely to be differential and rapid diagnosis was essential for optimal treatment.

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An Analysis of Elementary School Students' Interpretation of Data Characteristics by Cognitive Style (초등학생의 인지양식에 따른 자료해석 특성 분석)

  • Lim, Sung-Man;Son, Hee-Jung;Yang, Il-Ho
    • Journal of The Korean Association For Science Education
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    • v.31 no.1
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    • pp.78-98
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    • 2011
  • The purpose of this study was to analyze elementary school students' interpretation of data characteristics by cognitive style. Participants were elementary students in sixth grade who can use integrated inquiry process skills. The students were divided into two groups, analytic cognitive style and wholistic cognitive style according to their response to Cognitive Style Analysis. They performed scientific interpretation of data activity. To collect data for this study, participants recorded the result on scientific interpretation of data activity paper and researcher recorded the situation on videotape and interviewed with participants after the end of interpretation of data to get additional data. And the findings of this study were as follows: First, the study analyzed interpretation of data characteristics by the operator regarding different situations of interpreting data according to cognitive style. For example, in the intermediate state, analytic-cognitive style students showed high achievement in identifying variables, and wholistic-cognitive style students were active in using prior knowledge to interpret data. Second, the result of analysis on the direction of interpreting data and preference for data types in interpreting data activities according to cognitive style are as follows: Wholistic-cognitive style students showed relatively high perception of information through the top-down approach. On the other hand, analytic-cognitive style students usually used the bottom-up approach gradually expanding detailed information to the scientific question-related answer and showed a preference data of the table type. Through the result, this study aimed to help establish a data interpretation strategy for learners to solve problems based on understanding of interpretation of data characteristics according to learners' cognitive style, and purposed the instruction design suggesting the data requiring various data interpretation strategies to develop learners' data interpretation ability.

The Comparison of Methods Processing Cells Recovered by Bronchoalveloar Lavage (기관지폐포세척액에서 세포수 측정을 위한 처리방법의 비교)

  • Park, Jae-Seuk;Kim, Jae-Yeal;Lee, Gwi-Lae;Yoo, Chul-Gyu;Han, Sung-Koo;Shim, Young-Soo;Kim, Young-Whan
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.1
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    • pp.176-183
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    • 1998
  • Background: The total and differential cell count of bronchoalveolar lavage(BAL) fluid are useful assessing activity, prognosis and response to therapy in diffuse interstitial lung disease. But controversy exist as to the appropriate method in processing BAL fluid. Therefore we investigated the effect of gauze filtration, centrifugation and different storage time of BAL fluid on the total and differential cell count. Methods: We obtained BAL fluid from 6 persons with no active lung lesion and divided pooled BAL fluid into several siliconized glass tubes and filtered through 0, 1, 2, 4 folds of cotton guaze(pore size: 1mm), and compared total cell count using hemocytometer after trypan blue staining and differential cell count after Wright-Giemsa staining of cytocentrifuged preparations. And we also counted total and differential cell count after centrifugation(400g for 30 min) and various storage time(2hr, 24hr, and 48hr). Results: There was no difference in total and differential cell count according to folds of gauze filtraion. But without gauze filtration, mucus threads that hampered total and differential cell count were found in 2 cases (33%). Centrifugation resulted in loss of total cell count($24{\pm}18%$) without change in differential cell count. There was no change in total cell count after 2hr storage but significant cell loss was found after 24hr storage time(24hr : $28{\pm}21%$, 48hr : $41{\pm}24%$). However there was no change in differential cell count with 48hr storage time. Conclusion: Total and differential cell count of BAL fluid may be best performed after cotton gauze filtration without centrifugation and within 2 hours.

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