• Korean Journal of Construction Engineering and Management
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• v.8 no.3
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• pp.125-133
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• 2007

If project time extension were required in the construction projects, either liquidated damages or extension costs should be applied according to causation of the schedule delays. However, in actual cases it is not applied so far according to the contract conditions. The reason why this situation happened Is that function of the present planning and scheduling is not working feasibly. The CPM schedule could not provide a proper solution for apportioning responsibility for the schedule delays. This situation could be considered as breach of contract and will cause potential disputes for schedule delay. Therefore, in this research process based contract administration model for construction delay claim is proposed to prevent schedule delay and solve the claims. The model is based on pro-active management for causation of delay to provide apportionment of responsibility and written evidences.

• The Journal of Fisheries Business Administration
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• v.29 no.1
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• pp.27-63
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• 1998

This paper focuses on the history of fisheries finance in Korea, especially the role of fisheries finance after the establishments of korean fisheries cooperative. We can say that our fisheries was influenced greatly by the fisheries finance. It may be preyed by the facts that our fisheries experienced a great growth right after the input of big fisheries finance. The products of fisheries has increased from 1962 to now And the structure of the fisheries has improved. But there were unequal development in the each sectors of fisheries. Though the deep sea fishery and farming has developed faster, coastal fishing that are absorbing nearly 90% of fisheries population has stagnated. Of course it was because of unequal financial assistance by Authority. So to improve fisheries evenly, it is very important to overcome various problems that have encountered including the new circumstances like the WTO. For this, lots of steps should be taken. They can be summarized as follows. 1) It may be inevitable to see a rising costs in the deep sea fishery because of the declaration of EEZ by almost every nation. 2) So coastal fishing should be getting more important. It is necessary to improve the structure of coastal fishing and we should be ready to prepare various alternatives far self-sustained growth in coastal fishing. 3) Especially fisheries finance should play more active role. 4) Self-sustainable growth means a fishery with full compatability. For full compatability it is necessary to give financial supports far making fishing ground and equipping anti-pollution system and labour saving apparatus etc. 5) Also to raise the ratio of self-support in fisheries products it is necessary to give financial support to traditional financial system. 6) Moreover it is necessary to guide utilization of finance supplied. For this the committee that is consists of professional people in that field is strongly asked. This committee should be entitled to decide and coordinate the selection of projects, allocation of finance, method of utilization and evaluation of projects etc.

• Journal of Ginseng Research
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• v.27 no.4
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• pp.171-177
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• 2003

Previously we have reported that administration of Korean red ginseng water extract (KRG-WE) plays both preventive and therapeutic roles in testicular toxicity of guinea pigs exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Further study was carried out to verify the beneficial role of Korean red ginseng in TCDD-induced testicular toxicity with different animal species by different route of administration. Korean red ginseng crude saponin (KRG-CS) was prepared by Diaion HP-20 adsorption chromatography. One hundred twenty rats (Sprauge Dawley, 200${\pm}$10 g) were divided into 6 groups. The normal control group (NC) received vehicle (i.p.) and saline (p.o.). Predetermined dosage of TCDD (40 $\mu\textrm{g}$/kg b.w., i.p.) was administered to single TCDD-treated (TT) and test (CS) groups. KRG-CS was admin-istered (p.o.) at daily doses of 5 (CS5), 10 (CS10),20 (CS2O) and/or 40 mg/kg b.w. (CS40) for 5 weeks, starting 1 week before the TCDD-exposure. Body weight gain, organ weights, and sperm quality were investigated. Decrease in body weight gain induced by TCDD was greatly attenuated by KRG-CS in a dose-dependent manner. Testicular weight, sperm head counts and ratio of sperm with progressive movement in TT group decreased significantly but those parameters were improved by the treatment of KRG-CS in a dose-dependent manner. This result led us to conclude that crude saponin might be the active ingredient of Korean red ginseng that attenuates the testicular toxicity induced by TCDD.

• The Journal of Fisheries Business Administration
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• v.44 no.1
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• pp.91-103
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• 2013

When it comes to the development of a retail market, it has not only influenced the supply and sales of seafood, but it has also led to considerable changes in consumers' purchasing behavior and purchasing purposes. As consumers' incomes and lifestyles have improved, the tendency to purchase seafood has rapidly changed. In addition, the increase in two-income family incomes that resulted from women's active participation in society has increased the number of consumers purchasing home meal replacements (HMR) or convenience food rather than original food. With these changes in social-economic background and in consumers' needs, the purchase of seafood is gradually changing. As a result, companies are constructing diverse marketing strategies to satisfy their needs. Companies' marketing strategies have an immediate and vital effect on consumers' purchases of seafood. The most important and fundamental role is providing an opportunity for consumers to choose what to buy by being giving information and knowledge. In this paper, the purchasing behavior of consumers buying seafood will be examined with respect to their knowledge. First, which factors among a diverse range of marketing strategies exerted a significant impact on consumers' objectives and subjective knowledge was examined. Second, the study investigated which knowledge factors were important in influencing attitudes and purchasing purposes based on knowledge level. By comparing and analyzing factors related to consumers' knowledge with respect to seafood purchases, information is provided to inform companies about efficient strategies for marketing tactics.

• Informatization Policy
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• v.21 no.1
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• pp.77-98
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• 2014

The Korean government has been promoting the establishment of comprehensive information systems as one of supports for preschools' administration. This support is expected to enhance the efficiency of preschool education support systems and to improve the quality of educational services. The gap between government's expectation on an introduction of the information system and preschool educators' expectations has also been an issue in deploying this new system. This study identifies user resistance factors for comprehensive preschool administration assistance systems' deployment. We find that the performance expectancy, social influence, effort expectancy, and the psychological cost of user resistance have impacts on the user resistance. When these factors related resistance are resolved in the process of systems' deployment, active participation in these systems by preschool educators would be increased.

• Journal of Pharmacopuncture
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• v.21 no.4
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• pp.284-293
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• 2018

Objectives: Thymoquinone (TQ) is one of the active ingredients of herbal plants such as Nigella sativa L. (NS) which has beneficial effects on the body. The beneficial effects of TQ on the cardiovascular system have reported. This study aimed to investigate the effect of TQ on cardiac fibrosis and permeability, serum and tissue concentration of inflammatory markers and oxidative stress status in chronic lipopolysaccharide exposure in male rats. Methods: Seventy male Wistar rats were randomly divided into five groups as follows: (1) control; (2) LPS (1 mg/kg/day); (3-5) LPS + TQ with three doses of 2, 5 and 10 mg/kg (n=14 in each group). After 3 weeks, serum and cardiac levels of $IL-1{\beta}$, $TNF-{\alpha}$ and nitric oxide (NO) metabolites, and cardiac levels of malondialdehyde (MDA), total thiol groups, catalase (CAT) and superoxide dismutase (SOD) activities, permeability of heart tissue (evaluated by Evans blue dye method) and myocardial fibrosis were determined, histologically. Results: LPS administration induced myocardial and perivascular fibrosis and increased cardiac oxidative stress (MDA), inflammatory markers and heart permeability, while, reduced anti-oxidative enzymes (SOD and CAT) and the total thiol group. Administration of TQ significantly attenuated these observations. Conclusion: TQ improved myocardial and perivascular fibrosis through suppression of chronic inflammation and improving oxidative stress status and can be considered for attenuation of cardiac fibrosis in conditions with chronic low-grade inflammation.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.11
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• pp.1495-1504
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• 2018

The Moon administration has proposed three major directions for startup growth: the creation of a new environment, active investment, and the creation of a virtuous cycle in venture investment. The policy is progressive but not sufficient to create a startup innovation boom in the current Korean economic environment. ICT Startup support policies must pay more attention to the product release stage. For growth of startups and small businesses it is important to establish a close value chain to secure competitiveness in the global market. It is necessary to secure a bridgehead to advance into the global market, including technical cooperation with large companies and joint advancement overseas. The final goal of the startup policy should be the continuous growth of the national economy and the expansion of employment. The establishment of fair trade and the strengthening of the startup ecosystem are important to foster a startup-friendly environment. Funding programs requires a shift from general support to enhanced choice and focus.

• Journal of Ginseng Research
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• v.43 no.3
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• pp.354-360
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• 2019

Ginsenosides, the major active ingredients of ginseng and other plants of the genus Panax, have been used as natural medicines in the East for a long time; in addition, their popularity in the West has increased owing to their various beneficial pharmacological effects. There is therefore a wealth of literature regarding the pharmacological effects of ginsenosides. In contrast, there are few comprehensive studies that investigate their pharmacokinetic behaviors. This is because ginseng contains the complicated mixture of herbal materials as well as thousands of constituents with complex chemical properties, and ginsenosides undergo multiple biotransformation processes after administration. This is a significant issue as pharmacokinetic studies provide crucial data regarding the efficacy and safety of compounds. Moreover, there have been many difficulties in the development of the optimal dosage regimens of ginsenosides and the evaluation of their interactions with other drugs. Therefore, this review details the pharmacokinetic properties and profiles of ginsenosides determined in various animal models administered through different routes of administration. Such information is valuable for designing specialized delivery systems and determining optimal dosing strategies for ginsenosides.

• Mass Spectrometry Letters
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• v.10 no.2
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• pp.66-70
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• 2019

Rivaroxaban (RRN) is the first available active direct factor Xa inhibitor (anticoagulant) with oral administration. Due to its success in market, there have been efforts to develop various RRN formulations, and the development of good analytical methods for its in vivo evaluation is an essential prerequisite. Thus, here, a simple and efficient method to determine RRN in rat plasma using liquid-liquid extraction (LLE) and liquid chromatography and multiple reaction monitoring (LC-MRM) was presented. The use of ethyl acetate as the LLE solvent results appropriate extraction and purification of RRN and it also helps the significant reduction of rat plasma volume required for RRN quantitation. The developed method showed good analytical performance including specificity, linearity ($r^2{\geq}0.999$ within 0.5 - 500 ng/mL), sensitivity (the lower limit of quantitation at 0.5 ng/mL), accuracy (89.3 - 107.0%), precision (${\geq}12.7%$), and recovery (89.2 - 105.7%). Additionally, RRN in sample extracts showed good stability. Finally, the applicability of the validated method to the PK evaluation of RRN was confirmed after its oral administration to normal rats. The present method is the first analytical method employing LLE for the simple and efficient extraction and purification of RRN in rat plasma. Therefore, the present method can contribute to the development of new RRN formulations as well as to the monitoring of RRN in special clinical situations through its efficient determination in various samples with or without minor modification.

• Journal of the Korea Society of Computer and Information
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• v.26 no.9
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• pp.167-180
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• 2021

Since the mid-1990s, small and medium distribution and retail businesses have been experiencing difficulties due to the active entry of domestic and foreign distribution companies into the distribution industry. Accordingly, in 2003, the government established a small and medium distribution logistics center to secure self-sustainability and strengthen the competitiveness of small and medium distribution and retail businesses. However, in the rapidly changing distribution environment, small and medium distribution logistics centers were becoming increasingly difficult. To strengthen the management capabilities of small and medium distribution logistics centers, 4 primary factors (management operational ability, employee professional competency enhancement, product delivery, customer CS management) and 16 secondary factors were established based on literature research and FGI. We intend to derive the final weight and priority of these factors using AHP, and establish strategies to strengthen the competitiveness of small and medium distribution logistics centers.