• 제목/요약/키워드: Activation measures

검색결과 298건 처리시간 0.021초

The enhancing effect of Acanthopanax sessiliflorus fruit extract on the antibacterial activity of porcine alveolar 3D4/31 macrophages via nuclear factor kappa B1 and lipid metabolism regulation

  • Hwang, Eunmi;Kim, Gye Won;Song, Ki Duk;Lee, Hak-Kyo;Kim, Sung-Jo
    • Asian-Australasian Journal of Animal Sciences
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    • 제32권11호
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    • pp.1776-1788
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    • 2019
  • Objective: The demands for measures to improve disease resistance and productivity of livestock are increasing, as most countries prohibit the addition of antibiotics to feed. This study therefore aimed to uncover functional feed additives to help enhance livestock immunity and disease resistance, using Acanthopanax sessiliflorus fruit extract (ASF). Methods: ASF was extracted with 70% EtOH, and total polyphenolic and catechin contents were measured by the Folin-Ciocalteu and vanillin assay, respectively. The 3D4/31 porcine macrophage cells ($M{\Phi}$) were activated by phorbol 12-myristate 13-acetate (PMA), and cell survival and growth rate were measured with or without ASF treatment. Flow-cytometric analysis determined the lysosomal activity, reactive oxygen species levels (ROS), and cell cycle distribution. Nuclear factor kappa B ($NF-{\kappa}B$) and superoxide dismutase (SOD) protein expression levels were quantified by western blotting and densitometry analysis. Quantitative polymerase chain reaction was applied to measure the lipid metabolism-related genes expression level. Lastly, the antibacterial activity of 3D4/31 $M{\Phi}$ cells was evaluated by the colony forming unit assay. Results: ASF upregulated the cell viability and growth rate of 3D4/31 $M{\Phi}$, with or without PMA activation. Moreover, lysosomal activity and intracellular ROS levels were increased after ASF exposure. In addition, the antioxidant enzyme SOD2 expression levels were proportionately increased with ROS levels. Both ASF and PMA treatment resulted in upregulation of $NF-{\kappa}B$ protein, tumor necrosis factor $(TNF){\alpha}$ mRNA expression levels, lipid synthesis, and fatty acid oxidation metabolism. Interestingly, co-treatment of ASF with PMA resulted in recovery of $NF-{\kappa}B$, $TNF{\alpha}$, and lipid metabolism levels. Finally, ASF pretreatment enhanced the in vitro bactericidal activity of 3D4/31 $M{\Phi}$ against Escherichia coli. Conclusion: This study provides a novel insight into the regulation of $NF-{\kappa}B$ activity and lipid metabolism in $M{\Phi}$, and we anticipate that ASF has the potential to be effective as a feed additive to enhance livestock immunity.

A Study on the Measures to Activate Education Field of Maker Movement in Korea (국내 메이커 운동의 교육 분야 활성화 방안 연구)

  • Oh, Soo-Jin;Baek, Yun-Cheol;Kwon, Ji-Eun
    • Journal of Digital Convergence
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    • 제17권11호
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    • pp.483-492
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    • 2019
  • The culture and education are very active with the active policy and support to form the government's Maker Movement. The purpose of this study is to grasp the current status of the education sector of the domestic maker movement, which is increasing recently, and to propose a plan for activating maker education for the development of a positive direction. To this end, first, the current status and problems of domestic maker training are derived through in-depth interviews with existing maker training operators and participants. Second, based on the contents of the interview script, keyword analysis and its characteristics through the qualitative survey analysis program (NVIVO) are identified. Third, based on the analysis results, we propose a plan and development direction for domestic maker education. Based on the educators who performed maker training and the students involved, professional maker teachers were required for the professionalism of education, and the expansion of maker channels and professional networking of participating students was required. In addition, there was a need for specialized programs and appropriate policy support that reflected the characteristics of maker training. This study aims at contributing to the activation of maker education, which is a major field of maker movement, by helping to improve concrete support methods, training related educators, and educational environment for maker education.

A Study on the Development of Storytelling for Culture and Tourism Market Development - Based on Jecheon Central Market (문화관광형시장 육성을 위한 스토리텔링개발연구 - 제천중앙시장을 중심으로)

  • Park, Jin-Soo
    • Journal of Convergence for Information Technology
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    • 제8권6호
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    • pp.367-374
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    • 2018
  • The purpose of this research is to promote traditional markets, which are part of urban regeneration project, and to promote cultural and tourism market by applying characteristics and differentiated elements through story development through market-related resources in order to secure identity of the JeCheon Central market that lost function of the traditional market and regional aging of the traditional market. To this end, the basic survey and analysis of the Jecheon area and the current situation of the Jecheon Central Market were conducted to diagnose problems and to analyze keywords through surveys by local merchants and visitors. By drawing up measures to vitalize the Jecheon Central Market by floor and space, the Jecheon Central Market's design story is developed and applied so that it can restore the image of the local traditional market through regional and cultural elements and become a center of space and culture that can become a landmark for the region in the future. The storytelling designed for this purpose shall be linked to the spatial planning of each floor as well as the C.I. and exterior of the C.I. and the building of the Jecheon Central Market, and the identity of the Jecheon Central Market can be reestablishe.

Economic Analysis of Intelligent Security Service for Crime Prevention :Focused on Anyang City Security Demonstration District Project (범죄예방을 위한 지능형 방범 서비스 도입에 따른 경제성 분석 연구 :안양시 방범 실증지구 사업을 중심으로)

  • Yu, In-Jae;Han, Sun-Hee;Shin, Young-Seob;Lee, Jae-Yong
    • The Journal of the Korea Contents Association
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    • 제19권8호
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    • pp.667-676
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    • 2019
  • In recent years, the occurrence of life and violent crime in the city centered on crime-prone areas has become a big issue, raising the public interest in safety from crime has been higher than ever. As the initial response to crime and the importance of crime prevention are emerging, the government is preparing various measures such as crime prevention service using advanced technology. This project is a demonstration project to select specific target sites and apply that on a trial basis with the main purpose of commercialization of intelligent crime prevention technologies and services. In order to spread the business through the demonstration project, it is expected that the practical economic evaluation as well as the academic and practical value of the project will have a great significance. In this study, the purpose of this research is to derive economic feasibility through technologies and services to be implemented in Indokwon district of Anyang city, which is selected demonstration site of the intelligent security, to promote the spread of business and contribute to the policy activation.

A Study on Activation Plan of the Perception Survey Foundation for Specialized Library Librarian (특화도서관 사서의 인식조사 기반 활성화 방안 연구)

  • Noh, Younghee;Shin, Youngji;Kwak, Woojung
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • 제29권4호
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    • pp.91-111
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    • 2018
  • This study was carried out on specialized library librarians to investigate the status and overall satisfaction of specialized services and to compare the degree of importance and satisfaction of specialized subject data, specialized service places, specialization programs, specialized subject area facilities and environment based on ISA technique in order to derive problems and improvement measures for the operation of specialized libraries. As results, first, it was found that a specialized library subject should be selected based on the characteristics, history, and resources of the library location as well as based on the demand survey of the local residents and users. Second, based on the appropriate program type of specialized subject and the results from users' demand surveys, specialized libraries should develop different types of experience-type, lecture-type, view-type and the likes. Third, specialized library space types can be divided into integrated type, independent-in-integration type, and independent type. Even though it is most ideal to provide independently specialized space, the space must be constructed considering the circumstances and subject of specialization of each library. Fourth, specialized libraries should have at least one dedicated specialist in the corresponding subject. Dedicated specialists should provide lending and reference services related to the specialization such as tidying, browsing, reading and operating specialized programs. And a dedicated specialist must be an expert in the specialized subject and also a librarian who is responsible of the general library operation.

A Study on the Activation Measures of Library's Online Services to Overcome COVID-19 (코로나 19 극복을 위한 도서관 온라인서비스 활성화 방안에 관한 연구)

  • Noh, Younghee;Kang, Pil Soo;Kim, Yoon-Jeong
    • Journal of Korean Library and Information Science Society
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    • 제51권4호
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    • pp.185-210
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    • 2020
  • The library faced an unexpected crisis of COVID-19, and as a countermeasure strategy, non-face-to-face online service has been reinforced. Therefore, this study attempted to present a plan to overcome the challenges arising from rapidly changing external environment and current crisis. To this end, data search, electronic library, library service, cultural event and open space management status of 288 public libraries serviced as an integrated site were investigated. Based on this, the meaning of online services in the post-COVID-19 era and the implication of it were examined. As a result, first, the increase in the use rate of online data search services with the spread of non-face-to-face culture, second, the expansion of the services of the electronic library, third, the diversification of non-face-to-face, online services, fourth, expansion of online cultural event services, fifth, the diversification of open space services were proposed, sixth, Introduced an artificial intelligence system for unattended loan return based on access and the Seventh, expansion of experiential cultural support services and educational contents through VR, AR and MR. It is deemed necessary for the research on the future direction of the library's non-face-to-face services to be conducted by investigating the current status of online services in various types of libraries and the types and case studies of library services in the era of COVID-19.

Study on Damage Information Management Plan for Maintenance and Operation of River Facilities (하천시설 유지운영을 위한 손상정보 관리방안 연구)

  • Joo, Jae-Ha;Nam, Jeung-Yong;Kim, Tae-Hyung
    • Journal of the Computational Structural Engineering Institute of Korea
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    • 제34권1호
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    • pp.9-18
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    • 2021
  • Recently, the rapid proliferation, introduction, and application of the fourth industrial revolution technology has emerged as a trend in the construction market. Building Information Model (BIM) technology is a multidimensional information system that forms the basis of the fourth industrial revolution technology. The river sector utilizing this information-based system is also being actively reviewed, for example, the current measures for maintenance. In recent years, active research and current work should be done to reflect the need for river experts to introduce BIM into the river field. In addition, the development of tools and support software for establishing various information systems is essential for the activation of facility maintenance information systems reflecting advanced technology and to establish and operate management plans. A study on the maintenance of river facilities involves using existing drawings to build a three-dimensional (3D) information model, check the damage utilizing it, and inform it, and utilize it as the data for maintenance reinforcement. This study involved determining a method to build a river facility without the existing information system and using the property maintenance information with 3D modeling to provide a more effective and highly utilized management plan to check maintenance operations and manage damages.

Activation plan for the edible insect industry by improving perception (인식개선을 통한 식용곤충 산업의 활성화 방안)

  • Hwang, Dooseon;Lim, Chae-Hwan;Lee, Seung Hun;Yun, Eun-Young
    • Food Science and Industry
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    • 제55권2호
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    • pp.128-139
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    • 2022
  • Although edible insects are attracting attention as future alternative food because of their nutritional, eco-friendly, and economic advantages and functionality, consumption is low, so measures to promote consumption are needed. The problems in edible insect consumption were identified as the aversion to the edible insects, lack of publicity for edible insects newly registered in the Food Code, and difficulties in continuously supplying high-quality edible insects and selling products. To solve these problems, it is necessary to establish effective public relations plans for new edible insects and develop processing methods for improving their taste and flavor, education content about edible insects, and products interesting to the target age. In addition, it is necessary to establish a one-stop cluster that can perform quality control of harmful substances and nutrients, purchase raw materials, sell products, educate, and publicize.

Current Status and Improvement Measures for the Port State Control of Foreign Vessels in Domestic Port Calls (국내 기항 외국적 외항선 항만국통제 현황 및 개선방안)

  • Jeong, Kyu-Min;Hwang, Je-Ho;Kim, Si-Hyun
    • Journal of Navigation and Port Research
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    • 제46권4호
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    • pp.338-343
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    • 2022
  • As the revitalization of the global maritime industry continues, the number of foreign ships navigating the maritime territories of maritime neighboring countries has rapidly increased. However, large-scale marine accidents have occurred, caused by the insufficient establishment of a system for management and operation relative to vessels' safety-condition. To address that, the IMO has granted the right to exercise port state control, especially for foreign vessels, to countries with jurisdiction over maritime territories with strengthening regulations and guidelines. In particular, the Republic of Korea, as a member of the TOKYO MOU, is conducting PSC, but as of 2020, the proportion of foreign ships was three times higher than that of national ships that called in domestic ports. However, the inspection rate was low at 9% which has not met the recommended level by the TOKYO MOU. Thus, this study conducted an IPA analysis as well as content analysis, by collecting the practical opinions and views of PSCO through objective questionnaires and written expert interviews, for improving the efficiency and effectiveness of domestic PSC. As a result, it was derived that the importance and performance related to human factors such as life on board, working environment, and response to safety accidents should be improved in to raise the quality of PSC inspection. Additionally, the work environment and performance of PSC in domestic ports for foreign vessels could be improved, if multifaceted support bases are established, for administrative unification of related tests for PSC, recruitment of PSCO, activation of the defection-reporting system, reorganization of the PSC execution group, etc.

A Study on Critical Success Factors of Off-Site Construction - By Importance Performance Analysis - (IPA를 통한 OSC 핵심성공요인에 관한 연구 - 국내 PC기반 OSC를 중심으로 -)

  • Jung, Seoyoung;Yu, Jungho
    • Korean Journal of Construction Engineering and Management
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    • 제24권2호
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    • pp.24-36
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    • 2023
  • OSC is drawing attention to supplement limitations such as productivity problems and on-site safety and quality problems of existing on-site labor-oriented construction production methods. In order to activate the introduction and use of OSC in the domestic construction market, it is important to innovate the technology applied to each stage of OSC process (design and engineering, factory manufacturing, site assembly, and maintenance), but it is also necessary to develop a project management method suitable for OSC method. However, research related to OSC currently being conducted in Korea is mainly in terms of related technology development, and research on deriving project management measures for the success of OSC projects is insufficient. Therefore, it is time for research on deriving a project management plan based on the core success factors of the OSC project. Therefore, by conducting importance-performance analysis on 69 OSC critical success factors derived from the previous study, the study was conducted to derive key improvement factors for OSC introduction and utilization improvement and to provide implications for this. The results of this study are expected to have useful implications for the R&D planning and policy-making process for OSC activation in the future.