• Title/Summary/Keyword: Absorbed dose distribution

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Geant4-DICOM Interface-based Monte Carlo Simulation to Assess Dose Distributions inside the Human Body during X-Ray Irradiation

  • Kim, Sang-Tae
    • International Journal of Contents
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    • v.8 no.2
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    • pp.52-59
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    • 2012
  • This study uses digital imaging and communications in medicine (DICOM) files acquired after CT scan to obtain the absorbed dose distribution inside the body by using the patient's actual anatomical data; uses geometry and tracking (Geant)4 as a way to obtain the accurate absorbed dose distribution inside the body. This method is easier to establish the radioprotection plan through estimating the absorbed dose distribution inside the body compared to the evaluation of absorbed dose using thermo-luminescence dosimeter (TLD) with inferior reliability and accuracy because many variables act on result values with respect to the evaluation of the patient's absorbed dose distribution in diagnostic imaging and the evaluation of absorbed dose using phantom; can contribute to improving reliability accuracy and reproducibility; it makes significance in that it can implement the actual patient's absorbed dose distribution, not just mere estimation using mathematical phantom or humanoid phantom. When comparing the absorbed dose in polymethly methacrylate (PMMA) phantom measured in metal oxide semiconductor field effect transistor (MOSFET) dosimeter for verification of Geant4 and the result of Geant4 simulation, there was $0.46{\pm}4.69%$ ($15{\times}15cm^2$), and $-0.75{\pm}5.19%$ ($20{\times}20cm^2$) difference according to the depth. This study, through the simulation by means of Geant4, suggests a new way to calculate the actual dose of radiation exposure of patients through DICOM interface.

Determination of Dose Distribution under Nonequivalent Condition by Prosthesis in Radiotherapy (방사선 치료시 인공고관절 삽입에 의한 불균질면에서의 선량분포 평가)

  • Lee, Joon-Il;Kim, Sung-Hwan
    • Journal of radiological science and technology
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    • v.21 no.2
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    • pp.43-46
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    • 1998
  • When a patient was irradiated with prosthetic hip, the dose distribution was changed according to inhomogeneous materials. The density, effective atomic number, and the composition of material had influence on absorbed dose distribution. In this study, the influence of inhomogeneous material(Ti) was measured using a polyethylene phantom, which consisted of various diameter of titanium, with film dosimetry. As a result, the backward dose showed 29.5% increas by backscattering, the forward dose showed 28% decreas by absorption, and the side dose showed 7% increas by scattering, when 25 mm diameter Ti was used. In addition forward dose was in inverse proportion to the thickness of prosthetic material. When the prosthetic hip of patient is in an irradiated field, we must carefully study the absorbed dose distribution.

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Dose Estimation Model for Terminal Buds in Radioactively Contaminated Fir Trees

  • Kawaguchi, Isao;Kido, Hiroko;Watanabe, Yoshito
    • Journal of Radiation Protection and Research
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    • v.47 no.3
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    • pp.143-151
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    • 2022
  • Background: After the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, biological alterations in the natural biota, including morphological changes of fir trees in forests surrounding the power plant, have been reported. Focusing on the terminal buds involved in the morphological formation of fir trees, this study developed a method for estimating the absorbed radiation dose rate using radionuclide distribution measurements from tree organs. Materials and Methods: A phantom composed of three-dimensional (3D) tree organs was constructed for the three upper whorls of the fir tree. A terminal bud was evaluated using Monte Carlo simulations for the absorbed dose rate of radionuclides in the tree organs of the whorls. Evaluation of the absorbed dose targeted 131I, 134Cs, and 137Cs, the main radionuclides subsequent to the FDNPP accident. The dose contribution from each tree organ was calculated separately using dose coefficients (DC), which express the ratio between the average activity concentration of a radionuclide in each tree organ and the dose rate at the terminal bud. Results and Discussion: The dose estimation indicated that the radionuclides in the terminal bud and bud scale contributed to the absorbed dose rate mainly by beta rays, whereas those in 1-year-old trunk/branches and leaves were contributed by gamma rays. However, the dose contribution from radionuclides in the lower trunk/branches and leaves was negligible. Conclusion: The fir tree model provides organ-specific DC values, which are satisfactory for the practical calculation of the absorbed dose rate of radiation from inside the tree. These calculations are based on the measurement of radionuclide concentrations in tree organs on the 1-year-old leader shoots of fir trees. With the addition of direct gamma ray measurements of the absorbed dose rate from the tree environment, the total absorbed dose rate was estimated in the terminal bud of fir trees in contaminated forests.

Absorbed Dose from Large Balloon Filled with Liquid Ho-166

  • Joh, Chul-Woo;Park, Chan H.;Lee, Myoung-Hoon;Yoon, Seok-Nam;Kim, Mi-Hwa;Jang, Ji-Sun;Park, Kyung-Bae
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.328-330
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    • 2002
  • Large balloon angio catheter is used for Percutaneous Transluminal Angioplsty(TPA) of the iliac, femoral and renal arteries as well as after Transjugular Intrahepatic portosystemic shunt(TIPS). The use of angioplasty balloon filled with liquid form of radioisotope reduces the rate of restenosis after PTA. The purpose of this study was to evaluate the absorbed dose to the target vessels from various sized large balloon filled with liquid form of Ho-166-DTPA. Four balloons of balloon dilatation catheters evaluated were 5, 6, 8 and 10 mm in diameter. GafChromic film was used for the estimation of the absorbed dose near the surface of the balloon catheters. Absorbed dose rates are plotted in units of Gy/min/GBq/ml as a function of radial distance in mm from the surface of balloon. The absorbed dose rate was 1.1, 1.6, 2.2 and 2.3 Gy/min/GBq/ml at a balloon surface, 0.3, 0.4, 0.5 and 0.6 Gy/min/GBq/ml at 1 mm depth for various balloon diameter 5, 6, 8 and 10 mm in diameter respectively. The study was conducted to estimate the absorbed doses to the vessels from various sized large balloons filled with liquid form of Ho-166-DTPA for clinical trial of radiation therapy after the PTA. The absorbed dose distribution of Ho-166 appeared to be nearly ideal for vascular irradiation since beta range is very short avoiding unnecessary radiation to surrounding normal tissues.

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A New Method for Measuring the Dose Distribution of the Radiotherapy Domain using the IP

  • Homma, Mitsuhiko;Tabushi, Katsuyoshi;Obata, Yasunori;Tamiya, Tadashi;Koyama, Shuji;Kurooka, Masahiko;Shimomura, Kouhei;Ishigaki, Takeo
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.237-240
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    • 2002
  • Knowing the dose distribution in a tissue is as important as being able to measure exposure or absorbed dose in radiotherapy. Since the Dry Imager spread, the wet type automatic processor is no longer used. Furthermore, the waste fluid after film development process brings about a serious problem for prevention of pollution. Therefore, we have developed a measurement method for the dose distribution (CR dosimetry) in the phantom based on the imaging plate (IP) of the computed radiography (CR). The IP was applied for the dose measurement as a dosimeter instead of the film used for film dosimetry. The data from the irradiated IP were processed by a personal computer with 10 bits and were depicted as absorbed dose distributions in the phantom. The image of the dose distribution was obtained from the CR system using the DICOM form. The CR dosimetry is an application of CR system currently employed in medical examinations to dosimetry in radiotherapy. A dose distribution can be easily shown by the Dose Distribution Depiction System we developed this time. Moreover, the measurement method is simpler and a result is obtained more quickly compared with film dosimetry.

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Simulation and assessment of 99mTc absorbed dose into internal organs from cardiac perfusion scan

  • Saghar Salari;Abdollah Khorshidi;Jamshid Soltani-Nabipour
    • Nuclear Engineering and Technology
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    • v.55 no.1
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    • pp.248-253
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    • 2023
  • Directly, it is not possible to measure the absorbed dose of radiopharmaceuticals in the organs of the human body. Therefore, simulation methods are utilized to estimate the dose in distinct organs. In this study, individual organs were separately considered as the source organ or target organ to calculate the mean absorption dose, which SAF and S factors were then calculated according to the target uptake via MIRD method. Here, 99mTc activity distribution within the target was analyzed using the definition and simulation of ideal organs by summing the fraction of cumulative activities of the heart as source organ. Thus, GATE code was utilized to simulate the Zubal humanoid phantom. To validate the outcomes in comparison to the similar results reported, the accumulation of activity in the main organs of the body was calculated at the moment of injection and cardiac rest condition after 60 min of injection. The results showed the highest dose absorbed into pancreas was about 21%, then gallbladder 18%, kidney 16%, spleen 15%, heart 8%, liver 8%, thyroid 7%, lungs 5% and brain 2%, respectively, after 1 h of injection. This distinct simulation model may also be used for different periods after injection and modifying the prescribed dose.

Evaluation of Absorbed Dose for the Right Lung and Surrounding Organs of the Computational Human Phantom in Brachytherapy by Monte Carlo Simulation (근접방사선치료 시 몬테카를로 전산모사를 이용한 인체전산팬텀의 우측 폐와 주변 장기 선량평가)

  • Lee, Jun-Seong;Kim, Yang-Soo;Kim, Min-Gul;Kim, Jung-Soo;Lee, Sun-Young
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.443-451
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    • 2020
  • This study is to evaluate absorbed dose from right lung for brachytherapy and to estimate the effects of tissue heterogeneities on dose distribution for Iridium-192 source using Monte Carlo simulation. The study employed Geant4 code as Monte Carlo simulation to calculate the dosimetry parameters. The dose distribution of Iridium-192 source in solid water equivalent phantom including aluminium plate or steel plate inserted was calculated and compared with the measured dose by the ion chamber at various distances. And the simulation was used to evaluate the dose of gamma radiation absorbed in the lung organ and other organs around it. The dose distribution embedded in right lung was calculated due to the presence of heart, thymus, spine, stomach as well as left lung. The geometry of the human body was made up of adult male MIRD type of the computational human phantom. The dosimetric characteristics obtained for aluminium plate inserted were in good agreement with experimental results within 4%. The simulation results of steel plate inserted agreed well with a maximum difference 2.75%. Target organ considered to receive a dose of 100%, the surrounding organs were left the left lung of 3.93%, heart of 10.04%, thymus of 11.19%, spine of 12.64% and stomach of 0.95%. When the statistical error is performed for the computational human phantom, the statistical error of value is under 1%.

Evaluation of Photoneutron Dose in Radiotherapy Room Using MCNPX (MCNPX를 이용한 방사선 치료실의 광중성자 선량 평가)

  • Park, Eun-Tae
    • The Journal of the Korea Contents Association
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    • v.15 no.6
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    • pp.283-289
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    • 2015
  • Recently, high energy photon radiotherapy is a growing trend for increasing therapy results. Commonly, if you use high energy photons above 6~8 MeV nominal accelerator voltage, It lead the photo-nuclear reaction and the generation of photo-neutron are accompanied and these problematic factors are issued in the view of radiation protection. Therefore, in this study analyzed for dose distribution of photo-neutron in radiotherapy room based on MCNPX. As a result, absorbed dose is increased sharply from 10 MV to 12 MV. It was founded that the rapid increasement of photoneutron fluence was related to the absorbed dose at above 10 MV. Also, in case of the recommendation of ICRP 103, the outcome of an exchanged equivalent dose which based on calculated an absorbed dose, showed lower equivalent dose than ICRP 60 by reflecting the contribution of secondary photon for absorbed dose of human body in the low energy band.

Measurement of Absorbed Dose for High Energy Electron using $CaSO_4:Tm$ - PTFE TLD (고에너지 전자선의 흡수선량 측정에 있어서 TLD의 유용성)

  • Park, Myeong-Hwan;Kim, Do-Sung
    • Journal of radiological science and technology
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    • v.23 no.1
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    • pp.97-101
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    • 2000
  • In this study, the highly sensitive $CaSO_4:Tm$-PTFE TLDs has been fabricated for the purpose of measurement of high energy electron. $CaSO_4:Tm$ phosphor powder was mixed with polytetrafluoroethylene(PTFE) powder and moulded in a disk type(diameter 8.5 mm. thickness $90\;mg/cm^2$) by cold pressing. The absorbed dose distribution and ranges for high energy electron were measured by using the $CaSO_4:Tm$-PTFE TLDs. The ranges determined were $R_{100}=14.5mm$, $R_{50}=24.1mm$ and $R_P=31.8mm$, respectively and the beam flatness, the variation of relative dose in 80% of the field size, was 4.5%. The fabricated $CaSO_4:Tm$-PTFE TLDs nay be utilized in radiation dosimetry for personal, absorbed dose and environmental monitoring.

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Evaluation of absorbed dose in monkey and mouse using 18F-FDG PET and CT density information

  • Kim, Wook;Lee, Yong Jin;Park, Yong Sung;Cho, Doo-Wan;Lee, Hong-Soo;Han, Su-Cheol;Kang, Joo Hyun;Woo, Sang-Keun
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.3 no.1
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    • pp.18-24
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    • 2017
  • Patient-specific image-based internal dosimetry involves using the patient's individual anatomy and spatial distribution of radioactivity over time to obtain an absorbed dose calculation. Individual absorbed dose was calculated by accumulated activity multiply S-value of each organs. The aim of this study was to calculate the S-values using Monte Carlo simulation in monkey and mouse and evaluation of absorbed dose in each organ. Self-irradiation S-value of monkey heart self-irradiation was 3.15E-03 mGy-g/MBq-s, lung self-irradiation was 8.94E-04 mGy-g/MBq-s and liver self-irradiation S-value was 2.23E-03 mGy-g/MBq-s. Mouse heart self-irradiation S-value was 1.95E-01 mGy-g/MBq-s, lung was 9.59E-02 mGy-g/MBq-s, and liver was 1.40E-03 mGy-g/MBq-s. The results of this study show that the calculation protocol of image based individual absorbed dose of each organ using Monte Carlo simulation. Therefore, this study may be applied to calculate human specific absorbed dose.