• 대한본초학회지
• /
• 제25권4호
• /
• pp.129-135
• /
• 2010

Objectives : The present study was undertaken to determine whether the water extract of Achyranthis Radix, which is the roots of Achyranthes japonica (Achyranthis Radix, AR), is efficacious against collagen-induced arthritis (CIA) in DBA/1J mice. Methods : Mice were immunized with bovine type II collagen and orally treated with AR-W (50 and 100 mg/kg/bw) from days 21 to 42 after immunization. Arthritis was evaluated by arthritic score, histological examination of knee joint and serological markers such as TNF-${\alpha}$, $PGE_2$ and anti-type II collagen (C II)IgG. Results : The results showed that comparing with untreated CIA mice, treated with AR-W significantly suppressed the clinical score and joint tissue pathological damages, reduced the serum levels of TNF-${\alpha}$, $PGE_2$ and anti-C II IgG in CIA-mice. These results suggest that AR-W can effectively alleviate inflammatory response on CIA, and anti-inflammatoy of AR-W can be attributed, at least partially, to the inhibition of inflamamtory mediators, $PGE_2$ and TNF-${\alpha}$, in CIA. Conclusions : This study suggests that AR-W has a therapeutic potential in inflammatory joint diseases such as rheumatoid arthritis.

• 대한한방체열의학회지
• /
• 제6권1호
• /
• pp.39-48
• /
• 2008

Purpose: The purpose of this study is to report the effect of TKM to Rhumatitis Arthritis after parturition and show the importance of recuperation after parturation. Methods: The patient was a 33-year-old woman who complains arthralgia, edema and sense of coldness after her third parturation. The patient was treated by Herb medicine, Acupuncture treatment, Moxa treatment and Physical Treatment. And the progress of symtoms was evaluated by cheking the change of VAS, and inspecting the DITI. Results: The Pain and edema have declined. After discharge, she got definite diagnosis as Rhumatitis Arthritis. But We already estimated it from the results of serum test. So we had treated the patience with TKM and we could explain the prognosis. We regulated the pain and edema successfully at the acute phase. And the patient could take care of herself, she didn't play her disease down as a simple symptoms of parturation. Conclusion: TKM is expected to have positive effect on Rheumatic arthritis with quick onset after parturation.

• 한국전기전자재료학회논문지
• /
• 제23권10호
• /
• pp.820-825
• /
• 2010

In this study, we intended to design the optimal Fermi filter to apply the k-space date that is knee image of the rheumatoid arthritis patient acquired from the MRI (magnetic resonance imaging) instrument. After deciding the suitable coefficient for the Fermi filter, the results were compared with modified Fermi filter and inverse Chebyshev filter, Chebyshev filter, Elliptic filter and Butterworth filter. Firstly, in comparison to the results, the radiologist confirmed that modified Fermi filter was best decision for boundary of the rheumatoid arthritis images. The number of the black voxels of the histogram showed the quantity of the results. At the proposed filter images, numbers of the blacks voxels were statistically decreased. That meant voxels only appeared the black color were changed to others voxels color. Because the number of the total voxels was fixed, the area appeared block color could be effected to the other areas. If the modified Fermi filter were used for rheumatoid arthritis patient, the result will be better than other filters.

• 동의생리병리학회지
• /
• 제18권2호
• /
• pp.446-450
• /
• 2004

Objectives: In order to study the effects of Harpagophyti Radix in rats with arthritis induced by Freund's complete adjuvant. Methods : In this study, rats with arthritis induced by Freund's complete adjuvant were divided into four groups; Normal, Control, Sample A(Harpagophyti Radix 6mg/200g) and Sample B(Harpagophyti Radix 12mg/200g). After 1 week, separated searches were made on the change of edema rate, the count of WBC, the quantity of total protein, total bilirubin, GOT and GPT in the serum. Results: In the right plantar edema, both of Sample groups showed a decrease in comparison with Control group. In the count of WBC, the quantity of serum total protein and SGOT, Sample B showed a decrease with statistical significance in comparison with Control group. In the quantity of serum total bilirubin and SGPT, both of Sample groups did not show any harmful change in in comparison with Control group. Conclusion : Reviewing these experimental results, it appeared that Harpagophyti Radix showed the therapeutic effect of anti-inflammatation on adjuvant arthritis.

• 대한간호학회지
• /
• 제36권2호
• /
• pp.278-285
• /
• 2006

Purpose: This study was performed to verify the effect of Tai Chi exercise on patients with rheumatoid arthritis particularly their level of pain, fatigue, sense of balance and daily lift performance(ADL). Method: It employed a non-equivalent control group pre- and post-test design. The research instruments used in this study were pain, fatigue, sense of balance and ADL. Thirty-two patients in the experimental group carried out 50 minutes of Tai Chi exercise for 12 weeks, and 29 patients in the control group did not. Before and after the experiment, both groups were tested for pain, fatigue, sense of balance and ADL. Collected data were processed using the SPSS/WIN 10.0 program analyzed by the frequency, percentage, $x^2-test$, and t-test. Results: Pain and fatigue significantly decreased in the experimental group. However the improvement in ADL of the rheumatoid arthritis patients was not statistically significant but their sense of balance was enhanced significantly. Conclusion: Tai Chi exercise is an effective nursing intervention that can be used for rheumatoid arthritis patients.

• 대한본초학회지
• /
• 제27권3호
• /
• pp.1-6
• /
• 2012

Objectives : The present study was undertaken to evaluate whether Atractylodis Rhizoma Alba ethanol (ARA-E) extract, which is the pericarp of $Atractylodes$ $japonica$ Koidz. has an effect on collagen-induced arthritis (CIA) in mice. Methods : Male DBA/1J mice were induced by intradermal injection of bovine collagen-II in Freund's incomplete adjuvant (IFA). The CIA mice in the onset of arthritis were treated daily with oral administration of ARA-E extract at dose of 50 mg/kg/bw for 28 days. Arthritis index, histopathological changes and the levels of anti-type II collagen (CII) IgG and inflammatory cytokine, TNF-${\alpha}$ in sera of mice were measured to evaluate the antiarthritic effect of ARA-E. Results : ARA-E extract significantly decreased the arthritic scores and inhibited pathological changes of knee joint tissues in CIA mice. ARA-E extract also significantly decreased the serum levels of anti-CII IgG and TNF-${\alpha}$ in CIA mice. These results indicate that ARA-E extract may effectively prevent arthritic damages in CIA mice, at least partially, by inhibiting the production of autoantibodies and inflammatory cytokine. Conclusions : This studies suggest that ARA-E has a therapeutic potential in inflammatory joint diseases such as rheumatoid arthritis.

• 근관절건강학회지
• /
• 제11권1호
• /
• pp.7-17
• /
• 2004

In this paper, we checked health problems of patients who suffered from arthritis. After assessing each patients condition, in order to alleviate their sufferings, we introduced several methods of aromatherapy as a holistic approach to these health problems. Aromatherapy is used of essential oils, which are obtained from aromatic plants, can be defined as a nature-friendly complementary/alternative method, has its great merit in its each way of application. If the arthritis condition is localized, massage,compress or poultices, and hand or foot baths are most effective. Many of essential oils in the recipe have dual benefits, as anti-inflammative and analgesic agents. The Juniper and carrot seed aid in eliminating fluid and toxin accumulation in the joint and surrounding tissue. There are many different courses available and health professional should choose one that is relevant to clinical practice. Considering the future of nursing as a major contribution in the consumer-centered structure of medical health service, aromatherapy as a complementary/alternative method is expected to contribute not only to establishing more effective health service but also to resolving chronic health problems of arthritis.

• 근관절건강학회지
• /
• 제11권1호
• /
• pp.74-87
• /
• 2004

Purpose: This study aims to analyze the outcome of exercise programs for Rheumatoid Arthritis patients and its tendency with network analysis. Method: 30 articles from Medline search of foreign nursing journals(1966-2002) and 5 from three Korean nursing journals(1970-2002) were surveyed. The contents analyses were focused on outcome measures and network analysis of exercise programs. Results: Exercise programs result in improving muscle strength(91.7%), aerobic capacity(72.9%), and 50 feet walk time(57.3%). Among several exercises, water exercise, and Tai-chi are in the middle of weight-bearing exercises. In the experimental design, non-randomized control trials were 40%, and the functional status of subjects were not classified in 40% of the articles surveyed. Conclusion: Considering the results, muscle strength, aerobic capacity, and 50 feet walk time were tested as valid outcome measures. Tai-chi exercise could be recommended as proper exercise for Rheumatoid arthritis patients because of its low intensity of weight-bearing exercise. In terms of research methods, the randomized trials and functional classifications of rheumatoid arthritis should be done more strictly.

• 근관절건강학회지
• /
• 제6권2호
• /
• pp.185-196
• /
• 1999

The purpose of this study was to identify influencing factors adherence and dropout of aquatic exercise in patients who had been diagnosed chronic arthritis. Subjects were 54 patients with rheumatoid arthritis and osteoarthritis who had participated in the 6-week aquatic exercise program in Taejon metropolitan city. Data was collected from march 25 to April 25, 1999 through face to face and telephone interview. Result are as follows. Fourteen subjects(26.0%) were adherer who was keeping aquatic exercise. The reasons of aquatic exercise adherence were improvements of physical and affectional factors. And the major reasons of dropout was an environment factors(65.8%) and second reasons was physical factors(34.2%). Participants of friends(r=.34, p=.014) was significantly associated with the total duration of an aquatic exercise adherence. For these results, the nurse who care to patients with arthritis have to encourage to maintain aquatic exercise within six month after they begin aquatic exercise.

• 근관절건강학회지
• /
• 제11권2호
• /
• pp.153-164
• /
• 2004

The purpose of this study was to examine the effects of Tai-Chi for patients with chronic arthritis. This study was performed from 15th Sep. to 7th Nov. 2003, 57 arthritis patients were participated in the Tai-Chi program. Outcome measures were pain, fatigue, flexibility and balance. Data were analysed by $X^{2}-test$ and t-test. There were statistically significant in fatigue, and knee flexibility, but no significant differences were found in pain and balance. In conclusion, Tai-Chi program was proved to be an effective nursing intervention to increase the fatigue and flexibility. And the 12 forms of Tai-Chi program has been found safely applicable to the patients with chronic arthritis for 8 weeks.